Search clinical trials for: Pharmacokinetic medeling

Total 12726 results

Pfizer

Completed

A Phase I Study to Evaluate the Pharmacokinetics of Multiple Doses of Varenicline in Healthy Adolescent Smokers

Smoking Cessation

United States, United Kingdom
Pfizer

Completed

Drug Interaction Study Between Raltegravir And UK-453,061

Healthy Volunteers

United States
Aerovance, Inc.

Completed

A Phase 1 Safety and Pharmacokinetics Study of AER 001 Administered as a Dry Powder in Asthmatic Subjects

Asthma

United Kingdom
AstraZeneca

Completed

To Evaluate the Effect of Food on the Pharmacokinetics (PK) of AZD0328

Healthy

Sweden
AstraZeneca

Completed

Safety, Tolerability & PK of AZD0328 in Caucasian & Japanese

Healthy Volunteers

United Kingdom
IRCCS Policlinico S. Matteo

Unknown

Pharmacokinetics and Pharmacodynamics of MPA in Stable Renal Transplant Patients

Kidney Transplantation

Italy
Pfizer
Vicuron Pharmaceuticals

Completed

Safety, Tolerance and Pharmacokinetics of Anidulafungin in Immunocompromised Children Ages 2-17

Neutropenia

United States
S.L.A. Pharma AG

Completed

Evaluation of the Pharmacokinetics of Metronidazole 10% Ointment Applied Peri Anally in Healthy Volunteers and Patients With Perianal Crohn's Disease

Perianal Crohns'

United Kingdom
GlaxoSmithKline

Completed

Dose-Escalation Study Of SB-485232 Administered As Daily Subcutaneous Injections In Adults With Solid Tumors

Solid Tumor Cancer

United States
GlaxoSmithKline

Completed

Pharmacokinetic Study Of EPZICOM Tablet

HIV Infection

Japan
GlaxoSmithKline

Completed

A Study To Investigate The Effect Of Solabegron (GW427353) On Gastrointestinal Transit In Healthy Volunteers

Irritable Bowel Syndrome (IBS)

United States
GlaxoSmithKline

Completed

Dose-Escalating Study Of SB-485232 Administered Intravenously Every 28 Days To Adults With Solid Tumors Or Lymphomas

Lymphoma | Solid Tumor Cancer

United States
Biosynexus Incorporated

Completed

Safety and Pharmacokinetics Study in Adults for the Prevention of S. Epidermidis Infection in Low Birth Weight Infants

Staphylococcal Sepsis

United States
Inje University

Completed

The Effect of CYP3A Genetic Polymorphism on the Pharmacokinetics of Phosphodiesterase type5 Inhibitors in Male Subjects (CYP3APDE5I)

Healthy Subjects | Pharmacokinetics of Three PDE5Is | Genetic Polymorphic CYP3A5
Pfizer

Terminated

An Open-Label Study To Assess The Pharmacokinetics, Safety And Toleration Of Vfend®; Following Multiple Dosing With Vfend

Kidney Failure

United States
Eunice Kennedy Shriver National Institute of Child...
Children's Hospital of Michigan; Pediatric Pharmacology Research Units Network

Completed

An Open Label Evaluation of the Pharmacokinetics and Safety of Single Dose Intravenous Azithromycin in Preterm Neonates

Bacterial Infection | Ureaplasma

United States
Metronome Therapeutics

Unknown

Safety Study of Oral Vinorelbine in Subjects With Non-Hematologic Malignancies

Nonhematologic Malignancies

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone

Contraception | Hypogonadism

United States
Abbott

Completed

Study of a 6-Month Sustained-Release Formulation of Leuprolide Acetate in Prostate Cancer

Prostatic Neoplasms

United States
University of Southern Denmark
H. Lundbeck A/S

Completed

The Effect of Escitalopram on the Pharmacokinetics and Pharmacodynamics of Tramadol in Healthy Subjects

Healthy

Denmark
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Potential Pharmacokinetic (PK) Interaction Between Lecozotan and Digoxin

Alzheimer Disease
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

To Determine if There Are Pharmacokinetic Interactions at Plasma or Intracellular Level Between Nucleosides and Tenofovir

HIV

Spain
St Stephens Aids Trust

Completed

TMC 125 Blood Levels Study

HIV Infections

United Kingdom
Bionovo

Terminated

Phase I Study to Evaluate the Safety and Efficacy of MF101 as Well as the Pharmacokinetics of Its Key Active Components

Healthy

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb

Completed

A Phase I Safety and Pharmacokinetics Study of 2',3'-Dideoxyinosine (ddI) Administered Twice Daily to Infants and Children With AIDS or Symptomatic HIV Infection

HIV Infections

United States
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 26 PK: Rifapentine Pharmacokinetics in Children During Treatment of Latent TB Infection

Tuberculosis

United States, Canada, Brazil, Spain
EKR Therapeutics, Inc
Pacira Pharmaceuticals, Inc

Completed

A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery

Postoperative Pain
Assaf-Harofeh Medical Center

Unknown

Ocsaar and CYP2C9 Ploymorphism, Is There a Connection Between Pharmacokinetics, Pharmacodynamics and Pharmacogenetics?

Hypertension
National Institute of Allergy and Infectious Diseases...

Completed

A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin

HIV Infections | Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4-Immunoglobulin G (rCD4-IgG) Administered by Intravenous Bolus Injection in Combination With Oral Zidovudine in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
HemaQuest Pharmaceuticals Inc.

Completed

A Phase 1, Single-Dose Safety and Pharmacokinetic Study of Sodium ST20 in Healthy Volunteers

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Pharmacokinetics of Zidovudine and Oxazepam Alone and in Combination in the HIV-Infected Patient

HIV Infections

United States
ParaPRO LLC

Completed

A Pharmacokinetic (PK) Study of NatrOVA Topical Creme (1%) in Pediatric Subjects 6 to 24 Months of Age

Pediculosis Capitis (Head Lice)

United States
Bristol-Myers Squibb

Completed

Pharmacokinetics and Metabolism of Radiolabeled BMS-690514 in Healthy Male Subjects

Cancer

Switzerland
Boehringer Ingelheim

Completed

An Open-Label, Staggered Rising Dose Cohort Study Assessing the Pharmacokinetics, Safety, and Tolerance of BI-RG-587 in Combination With Zidovudine in Patients With HIV Infection (CD4+ Cell Count < 400/mm3)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Valproic Acid on Zidovudine Glucuronidation and Pharmacokinetics in HIV-Infected Patients.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Demonstrate That Anti-HIV Drug Therapy Can be Stopped Without Causing Viral Resistance, and to Characterize Drug Elimination From the Body

HIV Infections

United States
Merck Sharp & Dohme LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Pharmacokinetic Study of L-697,661 Alone and in Combination With Zidovudine

HIV Infections

United States
MediGene

Completed

Phase-I Study Evaluating the Pharmacokinetic Profile of RhuDex®

Pharmacokinetics

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Safety, Tolerability, Pharmacokinetics and 5 HT1A Receptor Occupancy

Alzheimer's Disease

Sweden
YM BioSciences

Completed

Study of Single and Multiple Doses of Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Healthy Subjects (LEF-2495)

Healthy

Canada
YM BioSciences

Completed

Study Evaluating Inhaled AeroLEF (Liposome-Encapsulated Fentanyl)in Normal Healthy Subjects

Healthy

Canada
French Innovative Leukemia Organisation

Completed

Liposomal Anthracyclin in the Treatment of Elderly ALL

Acute Lymphoblastic Leukemia

France
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Pharmacokinetics of a Single Ascending Dose of AZD1704

Pain

United Kingdom
Novartis

Completed

Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy Subjects.

Healthy

United States
Acrux DDS Pty Ltd

Completed

Pharmacokinetics of Testosterone Lotion in the Treatment of Hypogonadal Males

Hypogonadism

United States
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Healthy

United States
AstraZeneca

Completed

Pharmacokinetic Study of Esomeprazole Magnesium in Patients 1 to 11 Years-Old With Endoscopically-Proven Gastroesophageal Reflux Disease (GERD)

Reflux | Endoscopically-Proven GERD
Novartis

Completed

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Hepatic Insufficiency

United States
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study With Repeated Doses of Stalevo

Pharmacokinetics

Finland

3

Subscribe