Search clinical trials for: FLT3 Mutations

Total 1346 results

Cytonet GmbH & Co. KG
CRS Clinical Research Services Mannheim GmbH

Completed

Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function

Urea Cycle Disorders

Germany
Iceland Genomics Corporation
National Cancer Institute (NCI)

Completed

Studying Genes to Identify Melanoma in Patients in Iceland and Their Family Members

Melanoma (Skin)

Iceland
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
University of Copenhagen
Rhythm Pharmaceuticals, Inc.

Completed

Melanocortin 4 Receptor Mutations and Obesity-associated Diseases (Mc4Obes)

Obesity

Denmark
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Dose Escalation Study of ARQ 736 in Adult Subjects With Advanced Solid Tumors Harboring BRAF and/or NRAS Mutations

Solid Tumor

United States, Italy
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Withdrawn

Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer

Liver Cancer
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

DNA Analysis of Tissue Samples From Patients With Head and Neck Cancer

Head and Neck Cancer
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Studying Common Genetic Mutations Related to Mucositis in Patients With Multiple Myeloma Receiving High-Dose Melphalan

Mucositis | Multiple Myeloma and Plasma Cell Neoplasm

United States
Università Vita-Salute San Raffaele
IRCCS San Raffaele; Merck Sharp & Dohme LLC

Unknown

GePheRal: Clinical Validation of the Genotypic Diagnosis of Hiv-1 Resistance to Raltegravir by Parallel Analysis of the Genotype and Phenotype Profiles of Resistance

HIV-1 Infected Patients | Fold-change Resistance | Resistance Mutations

Italy
Cukurova University

Completed

MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Behçet's Disease

Turkey
Samsung Medical Center
AstraZeneca

Unknown

Evaluation of EGFR TKI Resistance Mechanism Using Plasma DNA Analysis

EGFR Mutation Positive Non-small Cell Lung Cancer

Korea, Republic of
Catholic University of the Sacred Heart

Unknown

Study With Trabectedin in BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Ovarian Cancer (MITO15)

BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype

Italy
AbbVie (prior sponsor, Abbott)

Completed

Kaletra: Therapy With Double Protease Inhibitors

Human Immunodeficiency Virus

Germany
AstraZeneca

Completed

Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec

Colorectal Cancer

United States
Chinese Society of Lung Cancer

Completed

Study of Pemetrexed Versus Gefitinib in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer Who Have Previously Received Platinum-Based Chemotherapy Without Epidermal Growth Factor Receptor (EGFR) Mutations

Non Small Cell Lung Cancer

China
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy and Safety Study of Sulfonylureas in Neonatal Diabetes Mellitus (GLIDKIR6-2)

Diabetes Mellitus

France
Spanish Lung Cancer Group
Merck Sharp & Dohme LLC

Terminated

Phase I/II of Oral Vorinostat Combination With Erlotinib in NSCLC Patients With EGFR Mutations With DP After Erlotinib.

Non-small Cell Lung Cancer

Spain
Korea University
GlaxoSmithKline

Completed

Adding Adefovir Dipivoxil Versus Switching to Entecavir in Patients With Lamivudine-resistant Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
Institut National de la Santé Et de la Recherche...

Unknown

Clinical, Molecular and by Neuroimaging of LRRK2 Mutations (LRRK2)

Parkinson's Disease

France
Memorial Sloan Kettering Cancer Center
Memorial Health University Medical Center

Completed

BRCA1 Haploinsufficiency and Gene Expression

BRCA1 Mutations

United States
AstraZeneca

Completed

Observational Study on the Management of Patients With Non Small Cell Lung Cancer Adenocarcinoma (MUTACT)

Non Small Cell Lung Cancer

France
Assistance Publique - Hôpitaux de Paris

Completed

Immunological Consequences of CARD15/NOD2 Mutations in Crohn's Disease (PLAC)

Crohn's Disease

France
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Dasatinib and Vorinostat in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Acute Lymphoblastic Leukemia

Leukemia

United States
University of Washington

Completed

AMD 3100 for Treatment of Myelokathexis

Neutropenia

United States
Vejle Hospital

Completed

Irinotecan and Panitumumab as 3rd Line Treatment for mCRC Without KRAS Mutations

Metastatic Colorectal Cancer

Denmark
University of North Carolina, Chapel Hill
Elizabeth Glaser Pediatric AIDS Foundation

Completed

Maternal TDF and FTC to Reduce NNRTI Resistance Mutations After Intrapartum NVP (TD-2)

Pregnancy | HIV

Zambia
National Cancer Institute (NCI)

Withdrawn

HLA-B35 Alleles and AIDS

HIV-1 | AIDS

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
University of California, Davis
National Cancer Institute (NCI)

Completed

Lapatinib and Vinorelbine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Vejle Hospital

Terminated

Pemetrexed and Gemcitabine for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations (PG)

Metastatic Colorectal Cancer

Denmark
Ionis Pharmaceuticals, Inc.
ALS Association; Muscular Dystrophy Association

Completed

Safety, Tolerability, and Activity Study of ISIS SOD1Rx to Treat Familial Amyotrophic Lateral Sclerosis (ALS) Caused by SOD1 Gene Mutations (SOD-1)

Familial Amyotrophic Lateral Sclerosis

United States
NYU Langone Health

Withdrawn

3.0 Tesla Magnetic Resonance Imaging for Breast Cancer Detection in High Risk Women

Breast Cancer | BRCA1 Mutation | BRCA2 Mutation

United States
Institut National de la Santé Et de la Recherche...
National Research Agency, France; Institut des Maladies Rares

Unknown

SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias (Spatax)

Cerebellar Ataxias | Spastic Paraplegias

Netherlands, France, Serbia, Belgium, Algeria, Denmark, Israel, Italy, Lebanon, Morocco, Norway, Portugal, Saudi Arabia, Tunisia, United Kingdom
Nationwide Children's Hospital
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Completed

Six Month Study of Gentamicin in Duchenne Muscular Dystrophy With Stop Codons

Duchenne Muscular Dystrophy

United States
Herlev Hospital
Odense University Hospital; Aalborg University Hospital

Completed

Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal Cancer (ICE)

Metastatic Colorectal Cancer

Denmark
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome

Kidney Cancer | Von Hippel-lindau Syndrome

United States
Fatebenefratelli and Ophthalmic Hospital
Niguarda Hospital; Mario Negri Institute for Pharmacological Research

Unknown

Tarceva Italian Lung Optimization tRial (TAILOR)

Non Small Cell Lung Cancer (NSCLC)

Italy
University Hospital, Antwerp
AstraZeneca; Universiteit Antwerpen

Completed

Study in NSCLC: is Timely Analysis of EGFR-mutation Status Feasible in Region Antwerp, Belgium. (HERMES)

Non Small Cell Lung Cancer

Belgium
Guangxi Medical University

Completed

Study on the Evolution of Genes Mutation Related With Gastrointestinal Stromal Tumors

Full Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing Approach | Investigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
Institut de Recherche pour le Developpement

Completed

One Month Dual Antiretroviral Prophylaxis to Prevent Resistance Mutations in Mothers Exposed to Single Dose Nevirapine

HIV Infections

Thailand
Chinese Lung Cancer Surgical Group
Zhejiang Cancer Hospital; Sun Yat-sen University; Fudan University; Chinese PLA... and other collaborators

Unknown

Erlotinib Versus Vinorelbine/Cisplatin as Adjuvant Treatment in Stage IIIA NSCLC Patients With EGFR Mutations

Non-small Cell Lung Cancer Stage IIIA

China
Bezmialem Vakif University

Unknown

BRAF V600E Mutations In Papillary Thyroid Carcinoma

Papillary Thyroid Carcinoma

Turkey
Abbott

Completed

Evaluation of Kaletra Therapy Over the Long-term

Human Immunodeficiency Virus

Germany
AstraZeneca

Completed

To Study the Changes in Protein in Lung Cells of Asian Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (PIONEER)

Non Small Cell Lung Cancer

Vietnam, Philippines, China, Hong Kong, Taiwan, Thailand, India
University Health Network, Toronto

Terminated

An Evaluation of the Development of Nevirapine Induced Mutations in HIV Patients Initiating or Discontinuing Combination Antiretroviral Therapy

Drug Resistance

Canada
ZhuGuangYing
Zhejiang Cancer Hospital; 307 Hospital of PLA; Fudan University; Cancer Institute... and other collaborators

Unknown

Radiotherapy Combined With Iressa for EGFR Mutation Positive Patients With Locally Advanced Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

China
IRCCS Policlinico S. Matteo
GlaxoSmithKline; University of Pavia; Azienda Ospedaliera di Padova; Azienda Ospedaliera... and other collaborators

Completed

Efficacy of Eltrombopag to Improve Thrombocytopenia of MYH9-related Disease

Blood Platelet Disorders

Italy
Clinical Research Center for Solid Tumor, Korea
Seoul National University Hospital; Korean Cancer Study Group

Terminated

A Study to Assess the Efficacy of Erlotinib for Leptomeningeal Carcinomatosis in EGFR Mutation Positive Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Leptomeningeal Carcinomatosis

Korea, Republic of
Provitro GmbH
Charite University, Berlin, Germany; AstraZeneca

Completed

Pathomolecular Analysis of Rare EGFR Mutations in Advanced NSCLC

Mutations in Exons 18 to 21

Germany
Illumina, Inc.

Completed

Detection of Factor V Leiden G1691A and Factor II (Prothrombin) G20210A Point Mutations in DNA

Detection and Genotyping of Factor V and Factor II Point Mutations

Search clinical trials for: FLT3 Mutations

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