Search clinical trials for: Bi-specific T-cell engager

Total 1655 results

Onxeo
Spectrum Pharmaceuticals, Inc

Completed

Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma

Lymphoma | Solid Tumor

United States, Denmark, United Kingdom
Onxeo

Completed

A Study of APO866 for the Treatment of Cutaneous T-cell Lymphoma

Cutaneous T-cell Lymphoma

Austria, France, Germany, Switzerland
National Cancer Institute (NCI)

Completed

Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma and other conditions

United States
Centre Leon Berard
The Biostatistics and Therapy Evaluation Unit; BEC (Department of Clinical...

Completed

Prognostic Value of Divpenia and CD4 Count in Relapsed Breast or Lung Cancer Patients (LYMPHOS1)

Breast Cancer | Lung Cancer

France
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms | Viral Infection

United States
Stefan Schieke MD

Withdrawn

Therapeutic Efficacy of Topical Sirolimus in Early Stage Cutaneous T-cell Lymphoma (CTCL)

Cutaneous T-cell Lymphoma (CTCL)

United States
Ontario Clinical Oncology Group (OCOG)
Sunnybrook Health Sciences Centre; Genzyme, a Sanofi Company

Completed

Alemtuzumab and CHOP Chemotherapy for Aggressive Histological Peripheral T-Cell Lymphomas (ACCAPELA)

Peripheral T-cell Lymphomas

Canada
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Withdrawn

Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers

Depression | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic...
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Resicard
union nationale de formation et d'evaluation en medecine cardio-vasculaire

Completed

Platform Therapeutic Education in Heart Failure and Coronary Disease (METISCARDIO)

Heart Failure | Acute Coronary Syndrome | Coronary Bypass Graft Stenosis of Native Artery Graft

France
University of Chicago

Terminated

Cord Blood Transplantation for Patients With Cancer

Hematological Disease

United States
National Cancer Institute (NCI)

Completed

Analysis of Genes Present in Cutaneous T-cell Lymphoma Cells

Lymphoma

United States
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia

Leukemia

United States
Merck Sharp & Dohme LLC

Completed

Vorinostat (MK-0683) Phase I Study in Cutaneous T-Cell Lymphoma (CTCL) Patients (MK-0683-089 EXT1)

Lymphoma
Hadassah Medical Organization

Terminated

A Study to Evaluate the Effect of ATG-F on Engraftment, Graft Versus Host Disease (GVHD) and Graft Versus Leukemia (GVL) Effect in Haplo-identical SCT

Graft Versus Host Disease | Allogeneic Haplo-Stem Cell Transplatation (SCT)

Israel
Merck Sharp & Dohme LLC

Terminated

An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED)

Lymphoma
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Previously Treated Non-Hodgkin's Lymphoma or Hodgkin's Disease

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic... and other conditions

United States
University of Pittsburgh

Completed

Immunization Against Tumor Cells in Sezary Syndrome

Sezary Syndrome | Cutaneous T-cell Lymphoma

United States
University of Pittsburgh

Completed

Effect of Denileukin Diftitox on Immune System in CTCL Patients

Mycosis Fungoides | Sezary Syndrome | Cutaneous T-cell Lymphoma

United States
Roger Williams Medical Center

Terminated

Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors

Neoplasms | Metastatic Cancer | Solid Tumors | Tumors

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Leukemia

United States
Helsinki University Central Hospital
Oulu University Hospital; Kuopio University Hospital; Tampere University Hospital and other collaborators

Completed

Oral Desensitization to Wheat in School Aged Children

Wheat Allergy

Finland
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

S9007, Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States
MedImmune LLC

Completed

A Study to Evaluate the Safety and Tolerability of MEDI-565 in Adults With Gastrointestinal Adenocarcinomas

Gastrointestinal Adenocarcinomas

United States
Samsung Medical Center
National Cancer Center, Korea; Asan Medical Center; Yonsei University; Korea Cancer...

Completed

RAD001 Combined With CHOP in Newly Diagnosed Peripheral T-cell Lymphomas (RADCHOP)

Cutaneous T Cell Lymphoma | Anaplastic Large Cell Lymphoma, ALK-negative | Angioimmunoblastic T Cell Lymphoma | Peripheral T Cell Lymphoma Unspecified

Korea, Republic of
Samsung Medical Center
Asan Medical Center; Yonsei University; Seoul National University; Chonnam National...

Completed

Concomitant Chemo-radiotherapy Followed by MIDLE Chemotherapy in Stage I/II Extranodal NK/T-cell Lymphoma

Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type

Korea, Republic of
Yale University
Eisai Inc.

Completed

A Pilot Study to Determine the Safety of the Combination of Ontak in Combination With CHOP in Peripheral T-Cell Lymphoma

Peripheral T-Cell Lymphoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
Bentong Yu
The Third Affiliated Hospital of Nanchang University

Completed

A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal Defect

Heart Septal Defects, Ventricular | Double Outlet Right Ventricle, Noncommitted VSD | Double Outlet Right Ventricle, Subaortic VSD | Double Outlet Right Ventricle, Subpulmonary VSD | Supracristal Ventricular Septal Defect

China
Bavarian Nordic

Completed

Safety and Immunogenicity Study of Recombinant Modified Vaccinia Virus Ankara (MVA) Virus to Treat HIV Infection

HIV Infections

Germany
Amgen Research (Munich) GmbH

Completed

Safety Study of the Bispecific T-cell Engager Blinatumomab (MT103) in Patients With Relapsed NHL

Non-Hodgkin's Lymphoma, Relapsed

Germany
NYU Langone Health
Memorial Sloan Kettering Cancer Center; National Institute of Arthritis and...

Completed

Role of Oral and Intestinal Microbiota in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis | Psoriatic Arthritis | Periodontal Disease

United States
Amgen Research (Munich) GmbH

Completed

Phase I Study of MT110 in Lung Cancer (Adenocarcinoma and Small Cell), Gastric Cancer or Adenocarcinoma of the Gastro-Esophageal Junction, Colorectal Cancer, Breast Cancer, Hormone-Refractory Prostate Cancer, and Ovarian Cancer (MT110-101)

Solid Tumors

Germany
Seagen Inc.
Genentech, Inc.

Completed

Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL

Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin

United States
Indiana University
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Determine the Effects of Gene Differences and Voriconazole on Enzyme CYP2B6 Activity in the Liver in Healthy Volunteers

Efavirenz, Metabolism and Pharmacokinetics Changes

United States
University College, London

Completed

Gemcitabine and Bexarotene in Treating Patients With Progressive or Refractory Stage IB, Stage II, Stage III, or Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma (GemBex)

Lymphoma

United Kingdom
Shanghai General Hospital, Shanghai Jiao Tong University...
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Unknown

ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors (HSCT)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma

China
Zenith Epigenetics

Withdrawn

Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML

Acute Myeloid Leukemia | Lymphoproliferative Malignancies

United States
National Cancer Institute (NCI)

Completed

RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States, Canada
National Cancer Institute (NCI)

Terminated

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Recurrent Childhood Acute Lymphoblastic Leukemia | T-cell Large Granular Lymphocyte Leukemia | T-cell Childhood Acute Lymphoblastic... and other conditions

United States, Canada
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0350 Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma

Lymphoma

United States
Sun Yat-sen University

Unknown

Mild-dose IMRT for Early-staged Extranodal Nasal-type NK/T-cell Lymphoma With CR Tumor After GELOX Chemotherapy

Lymphoma, | Non-Hodgkin Lymphoma, | Extranodal NK/T-cell Lymphoma,Nasal-type,

China
Indiana University School of Medicine
National Cancer Institute (NCI)

Completed

EMD 121974 in Treating Patients With Locally Advanced or Metastatic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
Red Cross Hospital, Hangzhou, China
First People's Hospital of Hangzhou; Sir Run Run Shaw Hospital; Zhejiang Provincial... and other collaborators

Unknown

Voriconazole for IPA in Chinese Patients With COPD (VIA-COPD)

COPD | Invasive Pulmonary Aspergillosis

China
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

SAHA + CHOP in Untreated T-cell Non-Hodgkin's Lymphoma

Lymphoma

United States
Solasia Pharma K.K.
Synex Consulting Korea Ltd.

Completed

A Phase 1 Study of SP-02L in Relapsed or Refractory Patients With Peripheral T-cell Lymphoma (PTCL) in Korea

Peripheral T-cell Lymphoma

Korea, Republic of
USDA, Western Human Nutrition Research Center
International Centre for Diarrhoeal Disease Research, Bangladesh; World Health...

Completed

Efficacy of Newborn Vitamin A Supplementation in Improving Immune Function

Vitamin A Deficiency

Bangladesh
Bayer

Completed

Compare Pharmacokinetic (PK) Profiles of Naproxen Sodium, Diphenhydramine Hydrochloride, and Naproxen Sodium and Diphenhydramine Hydrochloride Combination (Morpheus PK)

Therapeutic Equivalence

United States
University of Florida
Kellogg's Corporate Citizens Fund

Completed

Wheat Bioactives and Immune Function

Endocrine, Nutritional, Metabolic and Immunity Disorders

United States
Far Eastern Memorial Hospital

Unknown

Helical Irradiation of Total Skin (HITS) for T Cell Lymphoma

T-cell Lymphoma

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