Search clinical trials for: metformin (Glucophage®)

Total 15758 results

Yale University
National Institutes of Health (NIH)

Completed

Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance

Insulin Resistance | Pediatric Obesity | Hyperinsulinemia

United States
AstraZeneca
Biocard

Completed

An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed Conditions

Diabetes Mellitus, Type 2

Russian Federation
Gianna Wilkie

Not yet recruiting

Metformin Versus Standard of Care Treatment in Pregnant Women With Prediabetes

Prediabetes; Complicating Pregnancy

United States
Centre Hospitalier Universitaire, Amiens

Withdrawn

Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study (METsuiviIRC)

Renal Insufficiency, Chronic

France
Matthew Galsky

Completed

Metformin for Rising PSA Remote Trial (M-RePoRT)

Prostate Cancer

United States
University of California, San Francisco

Completed

Genetic Basis for Variation in the Renal Elimination of Metformin

Other Conditions That May Be A Focus of Clinical Attention

United States
University Health Network, Toronto

Completed

Phase II Lung Metcore - Preoperative Metformin for Lung Cancer (Metcore)

Lung Cancer | Non Small Cell Lung Cancer

Canada
West Virginia University
West Virginia Clinical and Translational Science Institute

Terminated

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

Cancer of Head and Neck

United States
Jewish General Hospital

Withdrawn

Endometrial Cancer Biomarker Changes Following Exposure to Metformin

Endometrial Cancer

Canada
The Baruch Padeh Medical Center, Poriya

Unknown

The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows

Infertility Female
University of California, San Francisco

Completed

Effect of Genetic Variants in MATE1 and OCT3 on the Pharmacodynamics of Metformin in African Americans (#6113)

Healthy | Type 2 Diabetes Mellitus

United States
University of California, San Francisco

Completed

Effect of Genetic Variation in the Transporter OCT2, MATE1 and MATE2-K on the PKPD of Metformin (#6112)

Healthy
Shahid Beheshti University of Medical Sciences

Completed

Safety of Continuing Metformin in Diabetic Patients With Normal Kidney Function Receiving Contrast Media

Diabetes Mellitus | Lactic Acidosis

Iran, Islamic Republic of
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Myocardial Perfusion in Type 2 Diabetes

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)

Type 2 Diabetes
Dana-Farber Cancer Institute

Completed

Exercise and Metformin in Colorectal and Breast Cancer Survivors

Breast Cancer | Colorectal Cancer

United States
Indiana Hemophilia &Thrombosis Center, Inc.

Active, not recruiting

Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency

Plasminogen Activator Inhibitor-1 Deficiency | Cardiac Fibrosis

United States
Sanofi

Completed

Phenotype Evaluation in Insulin Naive Patients Using Lantus (Insulin Glargine) (GALATEE)

Type 2 Diabetes

France
Geropharm

Completed

Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects

Bioequivalence

Russian Federation
Chinese University of Hong Kong

Recruiting

Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)

PsA (Psoriatic Arthritis)

Hong Kong
German University in Cairo

Recruiting

Clinical Evaluation of the Effect of Metformin in Sepsis

Sepsis

Egypt
University of Michigan Rogel Cancer Center

Active, not recruiting

A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL

Relapsed Chronic Lymphocytic Leukemia

United States
Centre Hospitalier Universitaire, Amiens

Completed

Efficacity and Safety of Metformin XR in CKD Stage 1 to 3 (METXR/CKD)

Renal Insufficiency, Chronic

France
Université de Sherbrooke
FRAXA Research Foundation

Completed

Metformin in Children and Adults With Fragile X Syndrome

Fragile X Syndrome

Canada
RenJi Hospital

Unknown

Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients

Polycystic Ovary Syndrome | Laparoscopic Sleeve Gastrectomy | Severe Obesity

China
Ahmed Maged

Completed

The Effect of Metformin on Different Hormones in PCOS Patients

Polycystic Ovarian Syndrome
VA Office of Research and Development
Northwestern University; University of Pittsburgh; San Francisco Veterans Affairs...

Recruiting

MetfOrmin BenefIts Lower Extremities With Intermittent Claudication (MOBILE IC)

Intermittent Claudication

United States
Anna Maria Storniolo
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer

Obesity | Breast Cancer

United States
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Recurrent Prostate Cancer | Stage I Prostate Cancer | Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
New York Medical College
Albert Einstein College of Medicine; University of Tennessee

Completed

EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance (EMPOWIR)

Obesity | Insulin Resistance | Hyperinsulinemia

United States
GlaxoSmithKline

Completed

BE STUDY OF METFORMIN GSK 1000mg (BA/BE 199/11)

Diabetic Foot
LG Chem

Unknown

Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

Type2 Diabetes
University of California, San Francisco
National Institute of General Medical Sciences (NIGMS)

Completed

Drug-Drug Interaction Study With Metformin and Nizatidine

Healthy

United States
NYU Langone Health

Completed

Metformin Prostate Cancer Adjuvant Trial

Prostate Cancer | Prostate Cancer Recurrent

United States
Cairo University

Unknown

Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

Oral Cancer

Egypt
Ain Shams University

Unknown

Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions

Oral Cancer

Egypt
Sandoz

Completed

A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions

Type 2 Diabetes
University of North Carolina, Chapel Hill
Foundation of Hope, North Carolina

Completed

Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth (PREVENT)

Weight Gain

United States
Columbia University
National Institute on Aging (NIA); Institute for the Study of Aging (ISOA)

Completed

Metformin in Amnestic Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment

United States
Radboud University Medical Center

Completed

The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) Trial (MetCAB)

Cardiovascular Disease | Ischemic Heart Disease

Netherlands
University of California, San Francisco

Completed

Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy Subjects

Other Conditions That May Be A Focus of Clinical Attention

United States
Glaser Pediatric Research Network
Elizabeth Glaser Pediatric AIDS Foundation

Unknown

Glaser Obesity Study

Obesity

United States
University of Colorado, Denver
US Department of Veterans Affairs

Completed

Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes (MeT1)

Type 1 Diabetes

United States
St. Louis University
Washington University School of Medicine

Completed

Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I

Diabetes Mellitus, Type 2 | Metformin Adverse Reaction

United States
Johns Hopkins University

Terminated

Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)

Obesity | Diabetes | Pre-diabetes

United States
University of Padova

Completed

Metformin and Longevity Genes in Prediabetes

Inflammation | Insulin Resistance | Aging | Prediabetes

Italy
Diabetes Frail Ltd
Merck Sharp & Dohme LLC; University of Campania "Luigi Vanvitelli"

Withdrawn

DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study) (DiaFrail)

Diabetes Mellitus
National Hepatology & Tropical Medicine Research...

Not yet recruiting

Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Egypt
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery

Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer
LG Chem

Completed

Bioequivalence Study for Fixed Dose Combination Zemimet® SR Tab. 50/1000 and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

Type 2 Diabetes

Thailand

Search clinical trials for: metformin (Glucophage®)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Netherlands

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations