Clinical Trials Sponsored by ANRS, Emerging Infectious Diseases

Total 262 results

ANRS, Emerging Infectious Diseases
MCM Vaccines B.V.

Completed

Trial Comparing Two Strategies of Vaccination Against Hepatitis B in HIV-infected Patients Non Responding to Primary Immunization (B-BOOST) (B-BOOST)

HIV Infection | Hepatitis B

France
ANRS, Emerging Infectious Diseases
Bristol-Myers Squibb

Completed

Therapy With Asunaprevir, Daclatasvir, Ribavirin and Pegylated Interferon Alpha-2a in HCV Genotype 4-infected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin (ANRS HC32 QUATTRO)

Hepatitis C Virus Genotype 4 Infection

France
ANRS, Emerging Infectious Diseases
Janssen-Cilag Ltd.

Terminated

Management of Participants With Low-level Persistent Viremia (ANRS 161 L-VIR)

Viremia | HIV-1 Infection | Treatment Resistant Disorders

France
ANRS, Emerging Infectious Diseases
MCM Vaccines B.V.

Completed

Trial Comparing Three Strategies of Vaccination Against the Virus of Hepatitis B in HIV Infected Patients (VIHVAC-B)

HIV Infections

France
ANRS, Emerging Infectious Diseases
Roche Pharma AG

Unknown

A Randomized Study to Assess the Loss of HbsAg After a 48-week Treatment Period With Pegylated Interferon Alpha 2a in Patients With Chronic Hepatitis B (PEGAN)

Chronic Hepatitis B | AgHbs Negativation

France
ANRS, Emerging Infectious Diseases
Roche Pharma AG

Completed

ANRS HC20 Effectiveness of an Optimized Anti HCV PegIFN-alpha2a + Ribavirin on Sustained Virological Response in Patients With HCV Genotype 1 and 4 Non Responders and Co-infected With HIV (ETOC)

Hepatitis

France
ANRS, Emerging Infectious Diseases
Institut Pasteur; Rockefeller University

Recruiting

Phase II Trial of ART + Dual bNAbs vs. ART + Placebo During Primary HIV-1 Infection-impact on Post-ART Control (RHIVIERA-02)

HIV/AIDS and Infections

France
ANRS, Emerging Infectious Diseases
Université Montpellier; Centre Muraz

Active, not recruiting

Cross Sectional Survey on the Burden, Impacts and Causes of Hepatitis C Virus (HCV) Outbreak in South West Region in Burkina Faso (REVERSO)

Chronic Hepatitis c | Hepatitis C Virus Infection, Past or Present

Burkina Faso
ANRS, Emerging Infectious Diseases
Gilead Sciences; Janssen Pharmaceutica

Completed

Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé) (2LADY)

HIV Infections | HIV

Burkina Faso, Cameroon, Senegal
ANRS, Emerging Infectious Diseases
EUCLID Clinical Trial Platform

Recruiting

ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation (IP-CURE-B)

Hepatitis B, Chronic

France, Germany, Italy, Spain
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC

Completed

Prevalence, Characteristics and Risk Factors of HIV-Associated Neurocognitive Disorders in Subjects Between the Ages of 55 and 70 Years: An Exposed/Unexposed Cross Sectional Study (HAND55-70)

HIV-1 Infection

France
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC

Completed

Renal Transplantation and Raltegravir in HIV-Infected Patients (ANRS153TREVE)

HIV-1 Infection | Chronic Renal Insufficiency

France
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC

Completed

Raltegravir in Patients With End Stage Liver Disease and in Transplant Recipients (LIVERAL)

Liver Failure | HIV Infection | Evidence of Liver Transplantation

France
National Institute of Allergy and Infectious Diseases...
ANRS, Emerging Infectious Diseases

Completed

A Study of LIPO-5 and ALVAC-HIV (vCP1452) as Possible HIV Vaccines

HIV Infections

United States
Imperial College London
ANRS, Emerging Infectious Diseases; Minka Therapeutics

Completed

3Sm Challenge Model Protocol

Healthy

United Kingdom
ANRS, Emerging Infectious Diseases
Bicetre Hospital; Pitié-Salpêtrière Hospital

Unknown

ANRS CO24 OncoVIHAC (Onco VIH Anti Checkpoint) (OncoVIHAC)

HIV Infected Patients With Cancer Treated by ICPi

France
Assistance Publique - Hôpitaux de Paris
ANRS, Emerging Infectious Diseases

Terminated

Primary Prevention Hepatocellular Carcinoma by Metformin (METFOVIR)

Hepatocellular Carcinoma | Hepatitis C, Chronic | Cirrhosis

France
Assistance Publique - Hôpitaux de Paris
ANRS, Emerging Infectious Diseases

Completed

Targeted Nurse-driven HIV Screening in Emergency Departments (DICI-VIH)

Targeted HIV Screening, Emergency Departments

France
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Unknown

BREATHER (PENTA 16) Short-Cycle Therapy (SCT) (5 Days on/2 Days Off) in Young People With Chronic HIV-infection (BREATHER)

HIV

United Kingdom, Uganda, Ireland, United States, France, Germany, Thailand, Ukraine
ANRS, Emerging Infectious Diseases
NEAT - European AIDS Treatment Network

Completed

Study of Darunavir/r + Tenofovir/Emtricitabine vs. Darunavir/r + Raltegravir in HIV-infected Antiretroviral naïve Subjects (ANRS 143)

HIV Infections

Ireland, United Kingdom, Netherlands, France, Spain, Greece, Belgium, Germany, Denmark, Sweden, Italy, Portugal, Austria, Hungary, Poland
Assistance Publique - Hôpitaux de Paris
ANRS, Emerging Infectious Diseases

Not yet recruiting

Education of Medical Staff to Post Acute Covid susTained sYmptoms (EMPATY)

Post-acute COVID-19 Syndrome

France
Intergroupe Francophone de Cancerologie Thoracique
ANRS, Emerging Infectious Diseases

Completed

Immunotherapy by Nivolumab for HIV+ Patients (CHIVA2)

HIV/AIDS | Non Small Cell Lung Cancer Stage IIIB | Non Small Cell Lung Cancer Metastatic

France
ANRS, Emerging Infectious Diseases
University of Bordeaux; PACCI Program

Unknown

Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase Randomized IIb Trial (INTENSE-COV)

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2 | COVID-19 Drug Treatment

Côte D'Ivoire
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Completed

KONCERT A Kaletra ONCE Daily Randomised Trial of the Pharmacokinetics, Safety and Efficacy of Twice-daily Versus Once-daily Lopinavir/Ritonavir Tablets Dosed by Weight as Part of Combination Antiretroviral Therapy in Human Immunodeficiency Virus-1 (HIV-1) Infected Children (PENTA 18) (KONCERT)

Antiretroviral Therapy in HIV-1 Infected Children

Netherlands, Germany, United Kingdom, Ireland, Thailand
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; ViiV Healthcare

Terminated

Evaluation of Raltegravir Plus Maraviroc Therapy in Controlled HIV Patients Presenting With Lipohypertrophy (ROCnRAL)

Human Immunodeficiency Virus | Lipohypertrophy

France
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis

HIV Infections | Tuberculosis

France, Brazil
ANRS, Emerging Infectious Diseases
National Institute on Drug Abuse (NIDA)

Completed

Feasibility of Interventions on People Who Inject Drugs in Vietnam (DRIVE-IN)

HIV | Substance Abuse | Hepatitis Virus

Vietnam
ANRS, Emerging Infectious Diseases
LinKinVax; Vaccine Research Institute (VRI), France

Recruiting

Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers.

COVID-19

France
ANRS, Emerging Infectious Diseases
Institute of Research for Development, France

Completed

Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B in the Rural Area of Niakhar, Senegal (AMBASS)

Chronic Hepatitis b

Senegal
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

Trial Evaluating a First Line Combination Therapy With Raltegravir, Emtricitabine and Tenofovir in HIV-2 Infected Patients (VIH-2)

HIV-2 Infection

France
ANRS, Emerging Infectious Diseases
UNITAID; Institut de Recherche pour le Developpement

Completed

Efficacy and Safety of a Dolutegravir-based Regimen for the Initial Management of HIV Infected Adults in Resource-limited Settings (NAMSAL)

HIV-1 Infection

Cameroon
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Janssen-Cilag Ltd.

Completed

Capacity of the Dual Combination Raltegravir/Etravirine to Maintain Virological Success in HIV-1 Infected Patients of at Least 45 Years of Age- ANRS 163 ETRAL

HIV-1 Infection

Spain, France
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Rennes University Hospital

Completed

Interest of Ribavirin in the Maintenance Treatment of Liver Fibrosis Using Low Dose Pegylated Interferon alpha2b in Patients With Chronic Hepatitis C Non Responders to Previous Antiviral Therapy.

Hepatitis C, Chronic | Liver Fibrosis

France, Belgium
ANRS, Emerging Infectious Diseases
UMR 1252 SESSTIM; ARCAD Santé PLUS; SEREFO

Unknown

ANRS 12392 Sanu Gundo (SANU GUNDO)

HIV Infections

Mali
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Rennes University Hospital

Completed

Boceprevir in HIV-HCV Coinfected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin (BocepreVIH)

HIV-1 Infection | HCV Coinfection

France
Rennes University Hospital
Ministry of Health, France; ANRS, Emerging Infectious Diseases

Completed

Treatment of Recurrent Hepatitis C After Liver Transplantation (TRANSPEG)

Liver Transplantation | Hepatitis C

France
ANRS, Emerging Infectious Diseases
St George's, University of London; Yaounde Central Hospital

Unknown

Pre-Antiretroviral Therapy (ART) Cryptococcal Antigen Screening in AIDS (PreCASA)

Cryptococcal Meningitis

Cameroon
ANRS, Emerging Infectious Diseases
Hopital Paul Brousse; University of Health Sciences, Cambodia

Unknown

HIV and HCV Infections in 2 Communes From the Battambang Province, Cambodia: Prevalence Rates, Viral Strains, and Unsafe Injection Practices (12352 ANRS ROK INVEST)

HIV Seropositivity | HCV Infection

Cambodia
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Ministry of Health, Brazil

Completed

Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis (REFLATE TB2)

Tuberculosis | HIV-1 Infection

France, Vietnam, Brazil, Côte D'Ivoire, Mozambique
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP)

Unknown

Evaluation of an Innovative Tuberculosis Diagnostic Test (PROMISE-TB)

HIV | Tuberculosis

Zambia
ANRS, Emerging Infectious Diseases
Institut Pasteur; National Hepatology & Tropical Medicine Research Institute

Withdrawn

Evaluation of the National Treatment Program of Hepatitis C in Egypt (eNTC)

Chronic Hepatitis C

Egypt
Calmy Alexandra
Oswaldo Cruz Foundation; ANRS, Emerging Infectious Diseases

Recruiting

Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease (UNITY)

Monkeypox | Mpox

Switzerland, Brazil, Argentina
ANRS, Emerging Infectious Diseases
Saint-Louis Hospital, Paris, France; Hôpital Cochin; Bichat Hospital

Not yet recruiting

Immunity to Yellow Fever in HIV-infected Patients 10 Years After a Primary Anti-yellow Fever Vaccination

HIV Infections | Yellow Fever
ANRS, Emerging Infectious Diseases
Programme PAC-CI; Centre Population et Développement (CEPED/IRD)

Recruiting

Feasibility and Effectiveness of a Pilot Program of Physical Activity to Improve HIV Related Functional Limitations and Disability in Adults Aged 40 and Older From Côte d'Ivoire (VIRAGE+)

HIV Infections

Côte D'Ivoire
Institut Pasteur
National Institute of Hygiene and Epidemiology, Vietnam; ANRS, Emerging Infectious...

Not yet recruiting

Evaluation of HCV Care and Treatment for HIV-HCV Co-infected Patients in Decentralised Areas in Vietnam (MOVIDA-Hep2)

HIV Infection | Hepatitis C Infection

Vietnam
Institut de Médecine et d'Epidémiologie Appliquée...
ANRS, Emerging Infectious Diseases

Recruiting

Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST) (NGS-IST)

Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Neisseria Gonorrhoeae Infection | Sexually Transmitted Infections (Not HIV or Hepatitis)

France
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP); European...

Recruiting

Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression (DATURA)

Tuberculosis | HIV-1-infection | Immuno-Deficiency

Uganda, Cambodia, Cameroon, Guinea, Vietnam, Zambia
French National Agency for Research on AIDS and...

Completed

Incidence of H1N1v Influenza-like Illness and Risk Factors for Serious Influenza Forms in HIV Infected Patients (ANRS 2H)

HIV Infections | Influenza

France
French National Agency for Research on AIDS and...

Terminated

Pioglitazone vs. Placebo in Association With Pegylated Interferon and Ribavirin in HCV Patients With Insulin Resistance (PEGLIST C)

Insulin Resistance | Chronic Hepatitis C

France
French National Agency for Research on AIDS and...

Completed

Patients Infected With HIV Since More Than 10 Years With a Plasma Viral RNA <400 Copies / mL in the Absence of Any Treatment: Study Mechanisms Involved in Controlling the Infection (ANRS CO18)

HIV Infection

France

Clinical Trials Sponsored by ANRS, Emerging Infectious Diseases

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