Clinical Trials Sponsored by Adagene Inc

Total 35603 results

Novan, Inc.
Synteract, Inc.

Completed

A Phase 3 Efficacy & Safety of SB206 & Vehicle Gel for the Treatment of MC (B-SIMPLE2)

Molluscum Contagiosum

United States
Genentech, Inc.
Seagen Inc.

Completed

A Study of the Safety and Pharmacology of SGN-40 Administered in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma
Mylan Inc.

Completed

Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain

Pain | Postoperative Pain | Pain, Acute

United States
Versartis Inc.

Terminated

Versartis Trial in Pre-pubertal Japanese Children With Growth Hormone Deficiency (GHD) to Assess Long-Acting Growth Hormone (Somavaratan, VRS-317)

Growth Disorders | Pediatric Growth Hormone Deficiency

Japan
Mylan Inc.

Completed

A Survey on Efficacy and Safety in Patients With Endometriosis

Endometriosis

Japan
Mylan Inc.

Completed

Special Investigation of LipaCreon on Long-term Use in Patients With Pancreatic Exocrine Insufficiency

Digestive System Diseases | Pancreatic Diseases | Exocrine Pancreatic Insufficiency

Japan
Mylan Inc.

Completed

Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Pancreatic Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Japan
Xoft, Inc.
Icad, Inc.

Completed

Feasibility Study of the Xoft® Axxent® Electronic Brachytherapy System for the Treatment of Cervical Cancer

Cervical Cancer

United States
TriHealth Inc.
Orthosensor, Inc.

Unknown

Making Sense Out of Total Knee Sensor Assisted Technology: A Randomized Control Trial

Arthroplasty, Replacement, Knee

United States
MolecuLight Inc.
SerenaGroup, Inc.

Unknown

Evaluation of MolecuLight i:X as an Adjunctive Fluorescence Imaging Tool to Clinical Signs and Symptoms for the Identification of Bacteria-containing Wounds

Wound

United States
Imara, Inc.
Quintiles, Inc.

Completed

A Study of IMR-687 in Healthy Adult Volunteers

Sickle Cell Disease | Sickle Beta 0 Thalassemia | Sickle-Cell; Hb-SC

United States
Eisai Inc.
Quintiles, Inc.

Completed

E7080 (Lenvatinib) in Combination With Dacarbazine Versus Dacarbazine Alone as First Line Therapy in Patients With Stage IV Melanoma

Stage IV Melanoma

United Kingdom, United States, Spain, Germany, Italy
Genentech, Inc.
23andMe, Inc.

Completed

An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)

Breast Cancer | Glioblastoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Renal Cell Cancer

United States
Centocor, Inc.
Quintiles, Inc.

Completed

A Study to Test the Design, Functionality, and Ergonomic Features of the Autoinjector

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Ankylosing Spondylitis

United States
Seagen Inc.
Genentech, Inc.

Terminated

A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL

Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin

United States, France, Spain, Belgium, Australia, Germany, Poland, Italy, Czech Republic, Hungary
Ocusoft, Inc.
ORA, Inc.

Completed

A Phase 4 Study Investigating the Efficacy of Retaine™ in Managing Signs and Symptoms Associated With Dry Eye Syndrome

Keratoconjunctivitis Sicca

United States
Pamlab, Inc.
InfoMedics, Inc.

Completed

Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support)

Major Depressive Disorder

United States
Genentech, Inc.
Seagen Inc.

Completed

A Study of SGN-40 in Combination With Rituximab in Patients With CD20-Positive, Follicular and Marginal Zone B-Cell Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma
Pamlab, Inc.
InfoMedics, Inc.

Terminated

Néevo®/NéevoDHA® P.L.U.S. Program (Progress Through Learning, Understand & Support)

Pregnancy

United States
Santen Inc.
MacuSight, Inc.

Completed

A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model

Dry Eye

United States
Santen Inc.
MacuSight, Inc.

Terminated

Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration

Age-related Macular Degeneration | Choroidal Neovascularization

United States
Santen Inc.
MacuSight, Inc.

Terminated

Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration (EMERALD)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
CrystalGenomics, Inc.
Quintiles, Inc.

Unknown

Phase II Study of CG100649 for Primary Osteoarthritis in Male Subjects

Osteoarthritis, Knee | Osteoarthritis, Hip

Germany
Aerovance, Inc.
Quintiles, Inc.

Completed

A Phase IIa Study of Subcutaneous AER 001 on Antigen Challenge In Atopic Asthmatic Subjects (28 Day Study)

Allergic Asthma

United Kingdom
Mylan Technologies Inc.
Mylan Inc.

Active, not recruiting

Study of the Safety and Efficacy of MR-100A-01 in Approximately 1200 Healthy Women for up to 13 Cycles

Contraception

United States, Canada, Puerto Rico
Santen Inc.
ActualEyes Inc.

Active, not recruiting

A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD) (PHANTOM)

Fuchs Endothelial Corneal Dystrophy

United States, France, India
SerenaGroup, Inc.
DrySee, Inc

Completed

A Comparison Between Two Post-operative Dressings (DrySee)

Surgical Incision

United States
Eisai Inc.
Quintiles, Inc.

Completed

A Study Comparing the Combination of the Best Supportive Care Plus E7080 Versus Best Supportive Care Alone, in Patients With Advanced Lung Cancer or Lung Cancer That Has Spread, Who Have Been Previously Treated, Unsuccessfully, With at Least 2 Different Treatments

Non-Small Cell Lung Cancer

Belgium, Korea, Republic of, Italy, United States, Hungary, United Kingdom, Czechia
Athersys, Inc
Medpace, Inc.

Completed

Study to Examine the Effects of MultiStem in Ischemic Stroke

Ischemic Stroke

United States, United Kingdom
Seagen Inc.
Genentech, Inc.

Completed

Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL

Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin

United States
Sequella, Inc.
Quintiles, Inc.

Completed

Escalating Single-dose Safety, Tolerability, and Pharmacokinetics of SQ109 in Healthy Volunteers

Tuberculosis

United States
Zogenix, Inc.
Synteract, Inc.

Completed

Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine

Migraine

United States
UNC Lineberger Comprehensive Cancer Center
AstraZeneca; Rgenix, Inc.

Recruiting

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

Non-Small Cell Lung Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Terminated

A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas

Follicular Lymphoma | Burkitt Lymphoma | Diffuse Large B-cell Lymphoma

United States
UNC Lineberger Comprehensive Cancer Center
G1 Therapeutics, Inc.

Recruiting

Study of Trilaciclib and Lurbinectidin

Lung Cancer | Small-cell Lung Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Cerulean Pharma Inc.

Terminated

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

Rectal Cancer

United States
Mylan Pharmaceuticals Inc
Momenta Pharmaceuticals, Inc.

Completed

Extension Study of MYL-1701P-3001 for Safety and Efficacy

Diabetic Macular Edema

India
Verrica Pharmaceuticals Inc.
BioClinica, Inc.; Paidion Research, Inc.; Instat Consulting, Inc.

Completed

A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts (CARE-1)

Skin Diseases | Sexually Transmitted Diseases, Viral | Sexually Transmitted Diseases | Skin Diseases, Infectious | Warts | Papillomavirus Infections | Skin Diseases, Viral | Condylomata Acuminata

United States
Genentech, Inc.
Flatiron Health, Inc.; Foundation Medicine, Inc.

Completed

Prospective Clinicogenomic Program (PCG)

Non-Small Cell Lung Cancer (NSCLC) | Small-Cell Lung Cancer (SCLC)

United States
Mylan Pharmaceuticals Inc
Momenta Pharmaceuticals, Inc.

Completed

Comparative Study to Evaluate the Efficacy and Safety of MYL-1701P and Eylea® in Subjects With Diabetic Macular Edema (DME) (DME)

Diabetic Macular Edema

Japan, United States, Czechia, Germany, Hungary, India, Latvia, Poland, Russian Federation
HeartBeam, Inc.
Meditrial USA Inc.

Not yet recruiting

AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection (VALID-ECG)

Atrial Fibrillation | Arrhythmias, Cardiac | Bradycardia | Tachycardia | Atrial Flutter

United States
GB002, Inc.

Recruiting

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Pulmonary Arterial Hypertension

United States, Spain, Israel, Korea, Republic of, Netherlands, France, Singapore, United Kingdom, Lithuania, Australia, Latvia, Argentina, Portugal, Greece, Czechia, Puerto Rico, Belgium, Italy, Poland, Romania, Serbia, Austria, Chile, Denma... and more
Combangio, Inc
Kala Pharmaceuticals, Inc.

Recruiting

Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED (CHASE)

Persistent Corneal Epithelial Defect

United States
Vivani Medical, Inc
Medpace, Inc.

Not yet recruiting

Assessment of Safety, Tolerability and Drug Levels of NPM-119 in Participants With Type 2 Diabetes (LIBERATE-1)

Type 2 Diabetes
Verastem, Inc.
Mirati Therapeutics Inc.

Recruiting

Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients (RAMP204)

Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung | Malignant Neoplastic Disease | KRAS Activating Mutation

United States
Criterium, Inc.
Novartis; Seagen Inc.

Recruiting

Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.

HER2-positive Metastatic Breast Cancer

United States
HBI Solutions Inc.
mProbe Inc.

Not yet recruiting

Development and Validation of a Multi-target, Blood-based NAFLD Diagnosis Test

NAFLD | NASH - Nonalcoholic Steatohepatitis
Neovasc Inc.
Shockwave Medical, Inc.

Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II (COSIRA-II)

Refractory Angina

United States, Canada
Cofactor Genomics, Inc.
Curebase Inc.

Recruiting

A Multicenter Cancer Biospecimen Collection Study

Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Cancer of Head and Neck | Lung Cancer, Nonsmall Cell | Gastroesophageal Junction Adenocarcinoma

United States
AVM Biotechnology Inc
Medpace, Inc.

Not yet recruiting

Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS (AVM0703)

Covid19 | Influenza, Human | ARDS

Clinical Trials Sponsored by Adagene Inc

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