Clinical Trials Sponsored by Burroughs Wellcome

Total 444 results

Glaxo Wellcome

Completed

Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors

HIV Infections

United States
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
Glaxo Wellcome

Completed

A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

HIV Infections | Lymphoma, Non-Hodgkin

United States
Glaxo Wellcome

Completed

A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination With Two Other Anti-HIV Drugs

HIV Infections

United States
Glaxo Wellcome

Completed

The Efficacy and Safety of Retrovir in Patients Infected With HIV Who Are Asymptomatic (CDC Group II) or Have Persistent Generalized Lymphadenopathy (CDC Group III)

HIV Infections | Lymphatic Disease

United States
Glaxo Wellcome

Unknown

Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy

HIV Infections

United States
Glaxo Wellcome

Unknown

Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)

HIV Infections

United States
Glaxo Wellcome

Completed

A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients

HIV Infections | Herpes Simplex

United States
Glaxo Wellcome

Completed

A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Retrovir in HIV-Infected Patients Who Have Problems Related to the Nervous System

HIV Infections

United States
Glaxo Wellcome

Completed

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of 524W91

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
University of North Carolina, Chapel Hill
Wellcome Trust

Completed

Impact of Environmental Nudges on Dietary Quality

Healthy Diet

United States
Bill & Melinda Gates Medical Research Institute
Wellcome Trust

Completed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV (MESA-TB)

Human Immunodeficiency Virus

South Africa
University of Oxford
Medical Research Council; Wellcome Trust

Terminated

Tofacitinib in Depression (TIDE) (TIDE)

Depression | Inflammation

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust

Unknown

Mitochondrial Donation: An 18 Month Outcome Study.

Mitochondrial Diseases

United Kingdom
University of Birmingham
Wellcome Trust; University Hospital Birmingham

Completed

Gellan Contact Study (GCS)

Thermal Injury | Skin Burn

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust

Completed

Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship (VAPRapid-2)

Ventilator-associated Pneumonia

United Kingdom
Professor Lorraine Harper
Wellcome Trust

Unknown

CMV Modulation of the Immune System in ANCA-associated Vasculitis (CANVAS)

ANCA Associated Vasculitis | CMV Infection

United Kingdom
Imperial College London
Medical Research Council; Wellcome Trust

Completed

Investigating Immunisation Strategies of DNA, MVA and CN54rgp140 Adjuvanted With GLA-AF to Maximise Antibody Responses (UKHVCSpoke003)

HIV

United Kingdom
American University of Beirut Medical Center
Wellcome Trust

Completed

Postpartum Support: Can we Facilitate the Transition to Motherhood?

Stress

Lebanon
American University of Beirut Medical Center
Wellcome Trust

Completed

Cocoa Butter for Prevention of Stretch Marks

Pregnancy | Striae Gravidarum

Lebanon
Glaxo Wellcome

Completed

A Comparison of Lamivudine and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Not Used Zidovudine in the Past

HIV Infections

United States, Canada, Puerto Rico
Glaxo Wellcome

Completed

The Safety and Effectiveness of Zidovudine Plus Acyclovir in Patients With Early HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases

HIV Infections | Neuromuscular Diseases | AIDS Dementia Complex

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of 935U83 in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in HIV-Infected Adults

HIV Infections

United States
Glaxo Wellcome

Completed

The Effect of Teaching HIV-Infected Patients About HIV and Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

A Pilot Randomized, Double-Blind, Placebo-Controlled, Parallel Design, Multicenter Trial to Evaluate the Effect of Ranitidine on Immunologic Indicators in Asymptomatic HIV-1 Infected Subjects With a CD4 Cell Count Between 400-700 Cells/mm3

HIV Infections

United States
Glaxo Wellcome

Completed

A Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Unknown

A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients

HIV Infections | Herpes Simplex | Herpes Genitalis

United States, Canada
Glaxo Wellcome

Completed

Treatment and Suppression of Hairy Leukoplakia in ARC Patients With Oral Acyclovir (ACV)

HIV Infections | Leukoplakia, Hairy

United States
Glaxo Wellcome

Completed

3TC (Lamivudine; GR109714X) Open-Label Program

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Two Anti-HIV Drug Combinations

HIV Infections

United States, Puerto Rico
Glaxo Wellcome

Completed

A Study of Retrovir in the Treatment of Psoriasis in HIV-Positive Patients

HIV Infections | Psoriasis

United States
Glaxo Wellcome

Completed

A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Study of 141W94 in Combination With Other Anti-HIV Drugs

HIV Infections

United States
Glaxo Wellcome

Completed

A Phase III Randomized Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of 3TC/ZDV/1592U89 and 3TC/ZDV/IDV in HIV-1 Infected Antiretroviral Therapy-Naive Subjects.

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

HIV Infections

United States
Glaxo Wellcome

Completed

The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus Disease

HIV Infections

United States, Puerto Rico, Australia
Glaxo Wellcome

Completed

Retrovir Capsules in the Treatment of HIV-Infected Patients in Renal Failure

HIV Infections | Kidney Failure, Chronic

United States
Glaxo Wellcome

Completed

A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

HIV Infections | Herpes Simplex

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of 1592U89 Plus 141W94 Plus DMP 266 in Patients With HIV Who Developed a Resistance to Protease Inhibitors

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of a Combination of Four Drugs in Patients With Recent HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT

HIV Infections

United States, Canada, Puerto Rico
Glaxo Wellcome

Completed

A Study of 1592U89 and Ethanol When Given Together to HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Canada, Puerto Rico

3

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