Clinical Trials Sponsored by CHILD-BRIGHT Network

Total 153 results

Andrea Gropman
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Longitudinal Study of Urea Cycle Disorders

Brain Diseases, Metabolic, Inborn | Amino Acid Metabolism, Inborn Errors | Urea Cycle Disorders

United States, Canada, Germany, Switzerland
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Microbicide/PrEP Acceptability Among Mothers and Male Partners in Africa (MAMMA)

HIV Prevention

Malawi, Zimbabwe, South Africa, Uganda
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT)

Infant, Newborn, Diseases | Premature Birth | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Other Preterm Infants | Infant, Small for Gestational Age

United States
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Rectal Microbicide Acceptability, Tolerability and Adherence

HIV Prevention

United States, Malawi, Peru, South Africa, Thailand
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Observational Study of HIV Infected Women Previously Enrolled in Other Microbicide Trials

HIV Infections

Malawi, Zimbabwe, Uganda, South Africa, Zambia
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Couple User Preferences in Dual Purpose Prevention Products (CUPID)

HIV Prevention | Contraception Behavior

Uganda, Zimbabwe
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Assessment of ASPIRE and HOPE Adherence

HIV Prevention

Zimbabwe, Malawi, South Africa, Uganda
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

An Exploratory Study of Potential Sources of Efficacy Dilution in the VOICE Trial (MTN-003)

HIV Prevention

Uganda, South Africa, Zimbabwe
Icahn School of Medicine at Mount Sinai
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Natural History of Apparent Mineralocorticoid Excess Syndrome

Apparent Mineralocorticoid Excess Syndrome

United States, Brazil, France
eSight Corporation
Johns Hopkins University; University Health Network, Toronto; University of Michigan and other collaborators

Completed

eSight Eyewear Quality of Life and Efficacy Study (eQUEST)

Vision, Low

Canada, United States
Advanced Tactile Imaging, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Cervix Monitor for Detection Conditions Leading to Spontaneous Preterm Delivery (CM)

Preterm Birth

United States
Boston Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Improving Preterm Outcomes by Safeguarding Maternal Mental Health

Depression | Child Development

United States
Women's College Hospital
University Health Network, Toronto; Sunnybrook Health Sciences Centre; Brigham... and other collaborators

Unknown

A Multi-centered Feedback and Education Intervention Designed to Reduce Inappropriate Transthoracic Echocardiograms

CARDIOVASCULAR DISEASES

Canada, United States
Ateneo de Manila University
University of Oxford; University of Cape Town; Bangor University; UNICEF; Philippine... and other collaborators

Completed

Parenting for Lifelong Health (PLH) - Masayang Pamilya (MaPa) Evaluation Study (PLH-MaPa)

Child Maltreatment

Philippines
Tufts Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

Obesity | Lifestyle-related Condition | Macrosomia, Fetal

United States
Tufts Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Salivary Profiling in Infants Treated for Suspected Sepsis: The SPITSS Study (SPITSS)

Infection; Newborn

United States
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial (OPUS)

Pelvic Organ Prolapse

United States
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM); University of Washington; Ankara University and other collaborators

Recruiting

A Hybrid Effectiveness/Implementation Trial of the International Guide for Monitoring Child Development

Child Development

Guatemala, India
Temple University
Albert Einstein Healthcare Network; Eunice Kennedy Shriver National Institute... and other collaborators

Recruiting

Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

Spinal Cord Injuries

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Hydrocortisone for BPD

Bronchopulmonary Dysplasia | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant, Premature | Infant, Newborn

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Systems Analysis and Improvement to Optimize pMTCT

HIV

Côte D'Ivoire, Kenya, Mozambique
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women

HIV Infections

United States, Malawi, South Africa, Zambia, Zimbabwe
Brigham and Women's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Genomic Sequencing for Childhood Risk and Newborn Illness

Genetic Predisposition to Disease | Hereditary Disease

United States
NICHD Neonatal Research Network
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

The Maternal Lifestyle Study (MLS) (MLS)

Pregnancy | Pregnant Women | Substance Abuse | Infant, Newborn | Prenatal Care | Cocaine

United States
NICHD Pelvic Floor Disorders Network
Johns Hopkins University; Eunice Kennedy Shriver National Institute of Child... and other collaborators

Terminated

Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse (E-CARE)

Urinary Incontinence | Prolapse

United States
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Prospective Evaluation of Infants With Spinal Muscular Atrophy: (SPOTSMA)

Spinal Muscular Atrophy

United States
University of Chicago
University of California, Los Angeles; Oak Foundation; UBS Optimus Foundation; Trickle... and other collaborators

Completed

Child Protective Outcomes Among Ultra-poor Families in Burkina Faso

Child Abuse | Child Maltreatment

Burkina Faso
University of Alabama at Birmingham
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Natural History of Rett Syndrome & Related Disorders

Rett Syndrome | CDKL5 Disorder | MECP2 Duplication dIsorder | FOXG1 Syndrome

United States
Aga Khan University
Aga Khan Health Services; Aga Khan Foundation, Pakistan; Centre for Global Child... and other collaborators

Terminated

Linking Facility-based Mortality Audits With Community Engagement in Gilgit-Baltistan, Pakistan

External Causes of Morbidity and Mortality | Stillbirth | Neonatal Death

Pakistan
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Training for Urinary Leakage Improvement After Pregnancy (TULIP)

Urinary Incontinence | Delivery Complication

United States
NICHD Global Network for Women's and Children's...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Global Network Implementation of Helping Babies Breathe (HBB)

Perinatal Mortality

Kenya, India
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
Memorial Sloan Kettering Cancer Center
Brigham and Women's Hospital; Weill Medical College of Cornell University; The... and other collaborators

Completed

Cognitive Changes Associated With Breast Cancer Treatment

Breast Cancer | Cognitive Side Effects of Cancer Treatments | Stage I, II and III A Breast Cancer

United States
Children's Hospital of Eastern Ontario
The Hospital for Sick Children; McGill University; Ottawa Hospital Research Institute and other collaborators

Unknown

Caring for Babies: A Study of Ontario Maternal-Newborn Hospitals on the Implementation of Parent-targeted Education (ONesiE)

Pain

Canada
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Refractory Overactive Bladder: Sacral NEuromodulation v. BoTulinum Toxin Assessment (ROSETTA) (ROSETTA)

Urinary Incontinence, Urge

United States
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Sling vs Botox for Mixed Incontinence (MUSA)

Urinary Incontinence, Stress | Urinary Incontinence, Urge

United States
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Neuromodulation for Accidental Bowel Leakage (NOTABLe)

Fecal Incontinence | Bowel Incontinence

United States
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Combined Treatment for Mixed Incontinence (ESTEEM)

Urinary Incontinence, Stress | Urinary Incontinence, Urge

United States
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe) (CAPABLe)

Fecal Incontinence

United States
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design (ASPIRe)

Visceral Prolapse

United States
University of Alabama at Birmingham
University of Colorado, Denver; Eunice Kennedy Shriver National Institute of... and other collaborators

Completed

Genetic and Physical Characteristics of Rett Syndrome

Rett Syndrome | MECP2 Duplication Disorder | Rett-related Disorder

United States
Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program (ScreenPlus)

Mucopolysaccharidosis II | Fabry Disease | Niemann-Pick Disease, Type C | Mucopolysaccharidosis VI | Lysosomal Acid Lipase Deficiency | Metachromatic Leukodystrophy | Gaucher Disease | Cerebrotendinous Xanthomatosis | Mucopolysaccharidosis IV A | GM1 Gangliosidosis | Mucopolysaccharidosis VII | Acid Sphingomyelinase... and other conditions

United States
Paris Translational Research Center for Organ Transplantation
Agence de La Biomédecine; Eurotransplant; United Network for Organ Sharing; Deutsche... and other collaborators

Unknown

COVID-19 Pandemic and Worldwide Organ Procurement (COVID)

COVID-19

France
Brigham and Women's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants

Genetic Predisposition to Disease | Hereditary Diseases

United States
Frank G. Holz
Radboud University Medical Center; Bayer; Hoffmann-La Roche; Novartis Pharmaceuticals and other collaborators

Active, not recruiting

Development of Novel Clinical Endpoints in Intermediate AMD (MACUSTAR)

Age Related Macular Degeneration (AMD)

Germany, Italy, Netherlands, United Kingdom, France, Portugal, Denmark
Dignity Health Medical Foundation
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital; St. Luke's... and other collaborators

Active, not recruiting

Left Atrial Posterior Wall and PV Isolation Using Cryoballoon for Treatment of Persistent AF (PIVoTAL-IDE)

Persistent Atrial Fibrillation

United States
Public Health Foundation Enterprises, Inc.
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

Comparison of Men's Prevention Apps to Research Efficacy (COMPARE)

Sexually Transmitted Diseases | HIV/AIDS | Risk Reduction | Pre-exposure Prophylaxis

United States
Memorial Sloan Kettering Cancer Center
University of California, Los Angeles; Ferring Pharmaceuticals; Wayne State University and other collaborators

Completed

3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy

Prostate Cancer

United States
University of Massachusetts, Worcester
Massachusetts General Hospital; Washington University School of Medicine; Yale... and other collaborators

Completed

REASON 1 Trial: Sonography in Cardiac Arrest

Cardiac Arrest | Pulseless Electrical Activity | Asystole

United States, Canada

Clinical Trials Sponsored by CHILD-BRIGHT Network

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations