Clinical Trials Sponsored by Cambridge Heart Inc.

Total 309 results

Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation (REAL-AF)

Paroxysmal Atrial Fibrillation | Persistent Atrial Fibrillation

United States
Saint Luke's Health System
Piedmont Heart Institute, Inc., Atlanta, GA

Active, not recruiting

Outcomes of Surgically Ineligible Patients With Multivessel CAD (OPTIMUM)

Coronary Artery Disease

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)

Intensive Care

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Cardiac Output Measurement at the Conclusion of Cardiopulmonary Bypass

Cardiac Output

United States
Menssana Research, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Unknown

Heartsbreath Test for Heart Transplant Rejection (Heartsbreath)

Heart Transplant Rejection

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Accurate Measurement of Cardiac Output Using the Ultrasound Dilution Technique (BCM)

Cardiac Output

United States
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers

Anemia, Sickle Cell

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Measurement of Cardiac Output Before and After Cardiopulmonary Bypass.

Cardiac Output

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Cardiac Output Measured by Ultrasound Dilution Method and Pulmonary Artery Thermodilution Technique

Cardiac Disease | Post Surgery Patients

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Measurement of Recirculation During Venovenous Extracorporeal Membrane Oxygenation (VV ECMO)

Venovenous Extracorporeal Membrane Oxygenation | Recirculation

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Estimation of Cardiac Output in Neonatal ICU Using an Ultrasound Dilution Technique (CH)

Neonatal Intensive Care

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients (GCH)

Cardiac Output

United States
Transonic Systems Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Measurement of Cardiac Output and Blood Volumes (WSU)

Cardiac Output

United States
ISA Associates, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Unknown

COPing With Shift Work - Web Based Program for Police Officers

Stress | Sleep Disorders

United States
Menssana Research, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Breath Test for Early Detection of Lung Cancer

Lung Neoplasms

United States
Radboud University Medical Center
Dutch Heart Foundation; Synvista Therapeutics, Inc

Completed

Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function

Cardiovascular Disease | Physical Activity | Aging | Endothelial Dysfunction

Netherlands
Cambridge University Hospitals NHS Foundation Trust
University of Pennsylvania; Roche Pharma AG; Genentech, Inc.; Arthritis Research...

Completed

Rituximab Vasculitis Maintenance Study (RITAZAREM)

Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Wegener Granulomatosis

United States, Canada, United Kingdom, Sweden, New Zealand, Ireland, Australia, Italy, Czechia, Japan
Shanghai Bio-heart Biological Technology Co., Ltd.
CCRF Inc., Beijing, China

Not yet recruiting

A Registry Trial of The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System

Coronary Artery Disease

China
Kaiser Permanente
National Heart, Lung, and Blood Institute (NHLBI); OCHIN, Inc.

Completed

SPREAD-NET: PRactices Enabling Adapting and Disseminating in the Safety NET (SPREAD-NET)

Cardiovascular Disease | Diabetes Mellitus

United States
Intermountain Health Care, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome

Lung Diseases | Acute Respiratory Distress Syndrome
Liverpool Heart and Chest Hospital NHS Foundation...
Biosense Webster, Inc.

Unknown

Pulmonary Vein Reconnection Following Ablation Index-guided Ablation: a Success Evaluation (PRAISE)

Atrial Fibrillation

United Kingdom, Italy
Liverpool Heart and Chest Hospital NHS Foundation...
Biosense Webster, Inc.

Completed

The Effect of Early Repeat Atrial Fibrillation (AF) Ablation on AF Recurrence (PRESSURE)

Atrial Fibrillation

United Kingdom
Shape Medical Systems, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Assessing the Utility of Submaximal CPET in Treatment Management of PAH

Pulmonary Arterial Hypertension

United States
Avidhrt Inc.
Michigan State University; ASCENSION SACRED HEART; Spring Arbor University

Not yet recruiting

Avidhrt Clinical Equivalence Study

Equivalence of ECG Electrode Type Signal Quality for AF and Non AF Users
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.

Terminated

Evaluating the Effectiveness of Adding Rituximab to Standard Treatment for Thrombotic Thrombocytopenic Purpura (TTP) (STAR)

Thrombotic Thrombocytopenic Purpura

United States
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.

Completed

Rituximab to Treat Severe Hemophilia A (RICH)

Hemophilia A

United States
Intermountain Health Care, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Risk Burden of Lipoprotein Metabolic Gene Haplotypes

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis
Montreal Heart Institute
Hopital du Sacre-Coeur de Montreal; ClearFlow, Inc.

Completed

Active Clearance of Chest Tubes After Cardiac Surgery: A Prospective Randomized Controlled Study (ACT-POAF)

Hemothorax | Atrial Fibrillation | Pleural Effusion | Cardiac Tamponade | Pericardial Effusion

Canada
Shanghai Bio-heart Biological Technology Co., Ltd.
CCRF Inc., Beijing, China

Active, not recruiting

Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study

Coronary Artery Disease | Antineoplastic Agents

China
Icahn School of Medicine at Mount Sinai
Heart Test Laboratories, Inc.

Completed

Analysis of Surface EKG Signals to Identify Myocardial Dysfunction in Patients at Risk for Coronary Artery Disease

Coronary Artery Disease

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI); Nuwellis, Inc.

Completed

Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study) (CARRESS)

Heart Failure

United States, Canada
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.; RTI International and other collaborators

Withdrawn

Pediatric High-Risk Deep Venous Thrombosis Lytic Outcomes Trial (PHLO)

Venous Thrombosis | Deep Vein Thrombosis | Post-Thrombotic Syndrome
Montreal Heart Institute
The Montreal Health Innovations Coordinating Center (MHICC); Ceapro Inc.

Completed

Compare the Efficacy and Safety of Beta-Glucan as Add-On to Statin in Subjects With Hyperlipidemia. (BetAvena)

Hyperlipidemias

Canada
CardioDx
Cardiovascular Research Foundation, New York; Piedmont Heart Institute, Inc...

Completed

Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES) (COMPASS)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); Healthways, Inc.

Completed

Evaluating Weight Loss Programs for Obese People at Risk for Heart Disease (The POWER Study) (POWER)

Obesity

United States
University of Rochester
National Heart, Lung, and Blood Institute (NHLBI); Eisai Inc.

Terminated

A Study of Dalteparin Prophylaxis in High-Risk Ambulatory Cancer Patients (PHACS)

Venous Thromboembolism | Pulmonary Embolism

United States, Canada
Montreal Heart Institute
The Montreal Health Innovations Coordinating Center (MHICC); Ceapro Inc.

Recruiting

Single and Multiple Ascending Oral Doses of Avenanthramide (AvenActive)

Inflammation

Canada
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); Aires Pharmaceuticals, Inc.

Completed

Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction

Heart Failure

United States
I.C. Van Gelder
Netherlands Heart Foundation

Active, not recruiting

Risk Profile for Patients With Atrial Fibrillation

Atrial Fibrillation

Netherlands
Duke University
National Heart, Lung, and Blood Institute (NHLBI); CAS Medical Systems, Inc.

Completed

Lidocaine For Neuroprotection During Cardiac Surgery

Cognitive Decline

United States
Innovaderm Research Inc.
Icahn School of Medicine at Mount Sinai; Montreal Heart Institute

Completed

Trial on Vascular Inflammation in Atopic Dermatitis

Atopic Dermatitis | Coronary Atherosclerosis | Vascular Inflammation

Canada
Kangdong Sacred Heart Hospital
Astellas Pharma Korea, Inc.; The Catholic University of Korea

Completed

Ramosetron, Aprepitant, and Dexamethasone Versus Palonosetron, Aprepitant, and Dexamethasone (RAPA)

Cancer | Tumors

Korea, Republic of
Oregon Center for Applied Science, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Interactive Web Program and Health Coaching for Prehypertensive Adults (Prehype)

Blood Pressure | Weight

United States
Linshom Medical, Inc.
National Heart, Lung, and Blood Institute (NHLBI); Ohio State University

Recruiting

Advanced Prediction of Respiratory Depression Episode With the Linshom Continuous Predictive Respiratory Sensor

Respiratory Complication | Post Surgical Respiratory Failure

United States
Aventyn, Inc.
Arizona State University; Intel Corporation; TwinEpidemic; Heart Health Organization...

Recruiting

Care Coordination to Assess Improvement in Outcomes in Hospital Readmissions (COMPASSION)

Heart Failure | ADHF | Acute MI

United States
NHS National Waiting Times Centre Board
British Heart Foundation; Siemens Healthcare Diagnostics Inc

Active, not recruiting

Detection and Significance of Heart Injury in ST Elevation Myocardial Infarction. (BHF MR-MI)

Acute ST-elevation Myocardial Infarction

United Kingdom
Vixiar Medical, Inc.
Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI)

Unknown

Heart Failure Event Advance Detection Trial (HEADstart)

Heart Failure | Congestive Heart Failure | Decompensated Heart Failure

United States
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.

Completed

Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure (GRAIL)

Respiratory Failure | Acute Respiratory Distress Syndrome | Acute Lung Injury

United States
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); Arizona Pharmaceuticals...

Completed

Effects of Niacin On Fatty Acid Trapping (NOFAT)

Dyslipidemia

United States
Dipan Shah
Piedmont Heart Institute, Inc., Atlanta, GA

Unknown

Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study (MITRA-REV)

Mitral Regurgitation

United States

Clinical Trials Sponsored by Cambridge Heart Inc.

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