Clinical Trials Sponsored by Edwards Lifesciences

Total 743 results

Edwards Lifesciences

Completed

Pulmonic Valve REplacement Multi-discIpline EMEA Registry (PREMIER)

Pulmonary Regurgitation | Pulmonary Insufficiency | Pulmonary Stenosis

Germany, Ireland, Belgium, Israel, United Kingdom, Italy, Poland, Saudi Arabia, Turkey
Edwards Lifesciences

Withdrawn

Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)

Cardiovascular Disease | Heart Disease | Heart Valve Disease | Mitral Insufficiency
Edwards Lifesciences

Terminated

V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet Prolapse

Mitral Leaflet Prolapse

Italy
Edwards Lifesciences

Completed

Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensive Care Unit Who Are Hemodynamically Unstable

Cardiac Output, Low | Cardiac Output, High

Switzerland, Finland
Optimapharm
Edwards Lifesciences

Active, not recruiting

RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis) (RHEIA)

Aortic Valve Stenosis | Heart Valve Diseases

United Kingdom, Italy, Germany, France, Austria, Switzerland, Finland, Czechia, Belgium, Netherlands, Cyprus, Ireland
Gérond'if
Edwards Lifesciences

Not yet recruiting

Evaluation of the Impact of Tricuspid Regurgitation on Patients Lives. Exploration of Experience and Impact on a Daily Basis. (EVOQUE)

Severe Tricuspid Regurgitation Medically Treated and Not Operated (Without Valve Replacement or Repair)
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
University of Giessen
Edwards Lifesciences

Active, not recruiting

Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery

Acute Kidney Injury | Hypotension | Anesthesia | ENT Disease

Germany
Montreal Heart Institute
Edwards Lifesciences

Completed

Paceport Swan-Ganz Data Collection Study

Congestive Heart Failure | Right Ventricular Dysfunction | Right Heart Failure

Canada
University of Zurich
Edwards Lifesciences

Unknown

Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation

Severe Degenerative Mitral Regurgitation

Switzerland
Massachusetts General Hospital
Edwards Lifesciences

Recruiting

Electronic Physician Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: The DETECT AS Trial (DETECT AS)

Aortic Stenosis

United States
Loma Linda University
Edwards Lifesciences

Completed

Prospective Data Analysis of a Quality Improvement Initiative in High Risk Cardiac Surgery Patients

Coronary Artery Bypass Graft

United States
Erasme University Hospital
Edwards Lifesciences

Completed

Effects of GlucoClear CGM System on the Performance of Insulin Therapy in Critically Ill Patients (GlucoClearIT)

Metabolic Stress Hyperglycemia
University of Giessen
Edwards Lifesciences

Not yet recruiting

Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension (Clearsight)

Acute Kidney Injury | Intraoperative Hypotension | Myocardial Injury After Non-cardiac Surgery
Montreal Heart Institute
Edwards Lifesciences

Recruiting

Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery (PACEPORT)

Congestive Heart Failure | Right Ventricular Dysfunction | Right Heart Failure

Canada
University Hospital, Montpellier
Edwards Lifesciences

Completed

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3 (DIRECTAVI)

Aortic Valve Stenosis

France
Baylor Research Institute
Edwards Lifesciences

Completed

Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study (SITRAL)

Mitral Annular Calcification

United States
University of Giessen
Edwards Lifesciences

Completed

The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery

Myocardial Injury | Renal Failure | Hypotension | Anesthesia | Hemodynamic Instability

Germany
Loma Linda University
Edwards Lifesciences

Terminated

Evaluation of Clinical Impact of Non-Invasive Hemodynamic Monitoring to Optimize Perioperative Care

Hemodynamic Monitoring

United States
Region MidtJylland Denmark
Edwards Lifesciences

Completed

Passive Leg Raising - an Important Diagnostic Manoeuvre (PLR-ANS)

Cardiovascular Insufficiency

Denmark
CAMC Health System
Edwards Lifesciences

Unknown

Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST) (FROST)

Critical Illness | Trauma

United States
Radboud University Medical Center
Edwards Lifesciences

Not yet recruiting

Post Anaesthesia Care Hypotension Prevention (PACH-1)

Hypotension During Surgery
Heinrich-Heine University, Duesseldorf
Edwards Lifesciences

Recruiting

VRAP-Heart - Virtual Reality Assisted Patient Empowerment for Interventions in Structural Heart Disease (VRAP-Heart)

Severe Aortic Valve Stenosis

Germany
University of Maryland, Baltimore
Edwards Lifesciences

Completed

Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation

Cardiac Surgery | Tricuspid Valve Regurgitation

United States
Shared Decision Making Resources
Edwards Lifesciences

Completed

Understanding Patient Goals and Preferences to Facilitate Shared Decision Making for Symptomatic Aortic Stenosis

Aortic Stenosis Symptomatic

United States
Edwards Lifesciences
Pacific Clinical Research Group

Completed

The SOLACE-AU Clinical Trial (SOLACE-AU)

Severe, Symptomatic Aortic Stenosis

Australia
Vanderbilt University Medical Center
Edwards Lifesciences

Completed

Enhanced Recovery After Surgery in Colorectal Surgery: A Large-Scale Quality Improvement Project (ERAS)

Colorectal Surgery | Perioperative Care | Quality Improvement | ERAS

United States
University Hospital Inselspital, Berne
Edwards Lifesciences

Completed

Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone

Vasodilation | Vasoconstriction | Hemodynamics | Cardiac Output, Low | Cardiac Output, High

Switzerland
University of British Columbia
Edwards Lifesciences

Recruiting

Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)

Aortic Stenosis | Aortic Valve Stenosis

United States, Canada
Edwards Lifesciences
American College of Cardiology

Completed

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII B (PARTNERII B)

Calcific Aortic Stenosis | Severe | Symptomatic

United States
University of British Columbia
Edwards Lifesciences

Completed

Cardiovascular Effects of Carbetocin Given During Elective Cesarean

Pregnancy | Effect of Carbetocin on Cardiovascular System

Canada
Baylor College of Medicine
Edwards Lifesciences

Recruiting

Outcomes of Pulmonary Valve Replacement With the INSPIRIS (Model 11500A) Valve

Heart Valve Prosthesis

United States
Vanderbilt University Medical Center
Edwards Lifesciences

Completed

A pragmatiC sTrategy to Promote actIVity and Enhance Quality of Life AFTER Transcatheter Aortic Valve Replacement

Aortic Valve Stenosis

United States
Charite University, Berlin, Germany
Edwards Lifesciences

Unknown

HIP Surgery - Hemodynamic Optimization Project (HipHop)

Redo Hip Surgery

Germany
Charite University, Berlin, Germany
Edwards Lifesciences

Terminated

Treatment of Severe Secondary TRIcuspid Regurgitation in Patients With Advance Heart Failure With CAval Vein Implantation of the Edwards Sapien XT VALve (TRICAVAL)

Severe Tricuspid Regurgitation

Germany
M.D. Anderson Cancer Center
Edwards Lifesciences

Completed

Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy

Liver Diseases | Gastrointestinal Diseases | Kidney Diseases | Esophageal Diseases | Prostate Cancer | Pancreatic Diseases | Gynecologic Diseases | Spinal Disease | Disorder of the Genitourinary System

United States
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Instituto Dante Pazzanese de Cardiologia
Edwards Lifesciences

Recruiting

Randomized Trial of Transcatheter Valve-in-Valve vs Redo Surgery for Bioprosthetic Mitral Dysfunction

Mitral Prosthetic Valve Stenosis and Regurgitation

Brazil
Edwards (Shanghai) Lifesciences Medical Supplies...

Completed

A Retrospective Study to Collect the Data From the Patients Who Had the Perimount Heart Valve Replacement Surgery in China During 2001 to 2007

Mitral Valve or Aortic Valve Replacement

China
Ottawa Heart Institute Research Corporation
Edwards Lifesciences

Completed

Transcranial Doppler (TCD) Assessment During Early Anti-thrombotic Therapy After Bioprosthetic Aortic Valve Replacement (Tissue-Valve)

Aortic Valve Disease

Canada
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Active, not recruiting

SAVR: IMPACT of Pre-existing Comorbidities on Patient Outcomes and Prosthetic Valve Performance in a Real-world Setting. (IMPACT)

Cardiovascular Diseases

Germany, Austria, Netherlands, Switzerland
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Active, not recruiting

Inspiris Resilia Durability Registry (INDURE)

Aortic Valve Stenosis

Austria, Belgium, France, Netherlands, United Kingdom, Germany, Italy, Canada, Spain
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Early Detection of Aortic Stenosis in the Community During Flu Vaccination (FluClinic)

Aortic Stenosis

United Kingdom
Edwards Lifesciences
DexCom, Inc.; Medical Device Consultants, Inc.

Completed

Clinical Study of the Intravenous Blood Glucose System in Hospitalized Adult Elective or Non-Emergent Surgery and Medical/Surgical Intensive Care Unit Patients

Blood Glucose

United States
Hamilton Health Sciences Corporation
McMaster University; Edwards Lifesciences

Recruiting

The JUMPSTART Program: Encouraging Early Mobilization and Optimizing Recovery of TAVR Patients' Post-hospital Discharge

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement

Canada
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

Circle Method Observational Project - Non-interventional, Retrospective, Multicenter International Data Collection

Aortic Stenosis With Bicuspid Valve

Italy
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, Switzerland, France, Italy, Germany, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Prospective Arm of Conduct - Edwards SAPIEN3 PPI Registry (Conduct-pro)

Aortic Valve Stenosis | Bundle-Branch Block | AV Block

Netherlands, Germany, Sweden
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Registry to Evaluate the Impact of a Valve Coordinator on Aortic Stenosis / TAVI Outcome - (German Pilot) (Coordinate)

Aortic Valve Stenosis

Germany
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Feasibility And Safety of Early Discharge After Transfemoral Transcatheter Aortic Valve Implantation (FAST-TAVI)

Aortic Stenosis

United Kingdom, Italy, Netherlands

Clinical Trials Sponsored by Edwards Lifesciences

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