Clinical Trials Sponsored by Genetics Institute

Total 75020 results

Genetic Disease Investigators

Completed

Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life

Venous Insufficiency | Postural Orthostatic Tachycardia Syndrome | Dysautonomia | Ehlers Danlos Syndrome | External Hydrocephalus

United States
Greenwood Genetic Center

Completed

Longitudinal Studies of the Glycoproteinoses

Galactosialidosis | Sialidosis | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Beta Mannosidosis | Mucolipidosis II | Mucolipidosis III | Schindler Disease

United States
Bionano Genomics
Columbia University; University of Iowa; Medical College of Wisconsin; Augusta... and other collaborators

Recruiting

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Intellectual Disability | Autism Spectrum Disorder | Fragile X Syndrome | Developmental Disability | Congenital Anomaly | Facioscapulohumeral Muscular Dystrophy 1

United States
NewLink Genetics Corporation
National Cancer Institute (NCI)

Completed

Vaccine Treatment for Advanced Non-Small Cell Lung Cancer

Lung Neoplasms | Adenocarcinoma of Lung | Non-small Cell Carcinoma | Squamous Cell Carcinoma | Large Cell Carcinoma

United States
Baylor Research Institute
Translational Genomics Research Institute

Recruiting

The TIOB - Collection of Patients' Biospecimens for Analysis of Immunological and Molecular Biomarkers. (TIOB)

Cancer

United States
Baylor Research Institute
Translational Genomics Research Institute

Unknown

Early Onset Alzheimer's Disease Genomic Study (TGen)

Alzheimer Disease

United States
Verge Genomics

Recruiting

A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Canada, Netherlands
Helio Genomics

Recruiting

Multi-analyte Blood Test Clinical Trial (LIVER-1)

Liver Cirrhosis | HCC | Hepatocellular Carcinoma | Liver Cancer

United States
Spinal Kinetics

Unknown

Restore CLINICAL TRIAL

Degenerative Disc Disease | Cervical Radiculopathy
Pathway Genomics

Completed

Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy

Colon Cancer | Colon Adenomas | Colon Polyps

United States
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

An Adaptive Clinical Trial of BeginNGS Newborn Screening for Hundreds of Genetic Diseases by Genome Sequencing (BeginNGS)

Genetic Disease

United States
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

Multiomic Diagnostics in Youth With Psychosis

Psychosis

United States
Scottsdale Healthcare
Translational Genomics Research Institute

Completed

Molecular Profiling Protocol (SCRI-CA-001)

Refractory Cancer

United States
Helsinki University Central Hospital
deCODE genetics

Active, not recruiting

Biomarkers of Neuropathic Pain in Women Treated for Breast Cancer

Breast Cancer | Neuropathic Pain

Finland
Hellenic Cooperative Oncology Group
NIPD Genetics

Completed

Tumor Molecular Profiling in Patients With Prostate Cancer

Prostate Cancer | Metastatic Prostate Adenocarcinoma

Greece
Icon Genetics GmbH
University Hospital, Ghent

Completed

Recombinant, Bivalent, Norovirus Vaccine Study

Norovirus

Belgium
British Columbia Cancer Agency
Insight Genetics

Completed

Comparison of qPCR to IHC and FISH for Detection of ALK Fusion Mutations in FFPE Tissue From NSCLC Patients (PCRTALK)

Nonsmall Cell Lung Cancer

Canada
University of Kiel
Interleukin Genetics, Inc.

Unknown

Genetics of Periodontal Diseases in European Caucasians

Periodontitis
Verge Genomics

Recruiting

A Study of VRG50635 in Healthy Volunteers

Healthy Volunteers

United States
Helio Genomics

Active, not recruiting

Clinical Trial Multi-analyte Blood Test (CLiMB)

Liver Cirrhosis

United States
Pathway Genomics

Terminated

ctDNA in Patients With Thyroid Nodules

Thyroid Cancer | Thyroiditis | Thyroid Adenoma | Thyroid Nodules

United States
Dana-Farber Cancer Institute
Nest Genomics

Recruiting

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Genetic Predisposition to Disease | Genetic Predisposition

United States
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

Rady Children's Institute Genomic Biorepository

Genetic Diseases

United States
Gattaca Genomics

Recruiting

Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing

Infertility | Aneuploidy | Infertility, Female | Infertility, Male | IVF

United States
Helio Genomics

Recruiting

Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer (ELITE)

Liver Cirrhosis | Diabetes | Cancer | Hepatitis B | Hepatitis C | COPD | Chronic Hepatitis

United States
Cadex Genomics

Completed

Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Non-Small Cell Lung Carcinoma

United States, Canada
Spinal Kinetics

Enrolling by invitation

M6-C Post Approval Study (PAS)

Long Term Follow-up

United States
Pathway Genomics

Completed

Utility of Plasma Circulating Tumor DNA (ctDNA) in Asymptomatic Subjects for the Detection of Neoplastic Disease (H1000)

Neoplasms | Mutation

United States
Pathway Genomics

Terminated

Circulating Tumor DNA in Patients at High Risk for Lung Cancer

Lung Neoplasms | Lung Cancer | Adenocarcinoma of the Lung | Cancer of the Lung | Small Cell Carcinoma of the Lung | Non Small Cell Carcinoma of the Lung

United States
Applied Genetic Technologies Corp

Completed

Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)

X-linked Retinoschisis

United States
Myriad Genetic Laboratories, Inc.

Completed

Combined Breast Cancer Risk Study

Hereditary Cancer

United States
Myriad Genetic Laboratories, Inc.

Terminated

Registry Measuring the Impact of Adding RNA Expression Testing on Referral Decisions in Early Stage Lung Cancer Patients and Assessing the Disease-free Survival With Long-term Follow-up (ONC003)

NSCLC | Lung Cancer | Lung Adenocarcinoma

United States
Iverson Genetic Diagnostics, Inc.

Suspended

Warfarin Adverse Event Reduction For Adults Receiving Genetic Testing at Therapy INitiation (WARFARIN) (WARFARIN)

Atrial Fibrillation | Pulmonary Embolism | DVT | Prosthetic Replacement of Mitral Valve | Anti-coagulation Therapy | Joint Surgery Multiple

United States
Myriad Genetic Laboratories, Inc.

Completed

Open Registry Measuring Impact of Genomic Testing on Treatment of Prostate Cancer Patients

Prostate Cancer

United States
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

Mental Health Crises in Youth With IDDs

Intellectual Disability

United States
Rady Pediatric Genomics & Systems Medicine Institute

Active, not recruiting

Newborn Genomic Sequencing Pilot Study

Genetic Disease

United States
Rady Pediatric Genomics & Systems Medicine Institute

Enrolling by invitation

Rapid Whole Genome Sequencing Study (rWGS)

Genetic Diseases | Genetic Syndrome

United States
Cyprus University of Technology
Cyprus Institute of Neurology and Genetics

Completed

The Effects of In-phase Bilateral Exercise in People With Progressive Multiple Sclerosis

Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

Cyprus
Centre Hospitalier Universitaire de Nīmes
Institute of Human Genetics, Montpellier

Active, not recruiting

Immunological Profiling of Patients With COVID-19 in Respiratory Distress (ACTICOV-2)

Covid-19 | SARS-CoV-2

France
Applied Genetic Technologies Corp
National Eye Institute (NEI)

Completed

Clinical and Genetic Characterization of Individuals With Achromatopsia

Achromatopsia

United States
General Oncology, Inc.
Myriad Genetics, Inc.

Recruiting

SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | BRCA1 Mutation | BRCA2 Mutation | Pancreatic Acinar Cell Carcinoma | Metastatic Pancreatic Cancer | Breast Cancer Metastatic | HER2-negative Breast Cancer | Metastatic Pancreatic Ductal Adenocarcinoma and other conditions

United States
Kaohsiung Medical University
Interleukin Genetics, Inc.

Unknown

Genetics of Periodontal Diseases in Chinese (Taiwan)

Periodontal Disease
Ochsner Health System
NewLink Genetics Corporation

Unknown

A Phase II Study of an Anti-Tumor Immunotherapy Regimen Comprised of Pegylated Interferon-Alpha 2b and HyperAcute Melanoma Vaccine for Subjects With Advanced Melanoma

Melanoma

United States
Targeted Genetics Corporation
Cystic Fibrosis Foundation

Terminated

Safety and Efficacy of Recombinant Adeno-Associated Virus Containing the CFTR Gene in the Treatment of Cystic Fibrosis

Cystic Fibrosis

United States
Myriad Genetic Laboratories, Inc.

Recruiting

Long-Term Prospective Registry in Prostate Cancer Patients From Diverse Urology Practice Settings Following Prolaris® Testing

Prostate Cancer

United States
Myriad Genetic Laboratories, Inc.

Terminated

Study Comparing Optimized 5-FU Dosing and Standard Dosing in Metastatic Colorectal Cancer Patients Treated With mFOLFOX6 (PROFUSE)

Colorectal Cancer, Metastatic

United States
Applied Genetic Technologies Corp

Completed

Clinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP)

X-Linked Retinitis Pigmentosa

United States
Myriad Genetic Laboratories, Inc.

Completed

Clinical Outcomes in Men With Prostate Cancer Who Selected Active Surveillance Using Prolaris® Testing (URO-009Low)

Prostate Cancer

United States
Myriad Genetic Laboratories, Inc.

Terminated

Registry Measuring Impact of RNA Expression Testing on Treatment Decisions in Early Stage Lung Cancer and Assessing the Disease-free Survival With Long-term Follow-up (ONC006) (ONC006)

NSCLC | Lung Cancer | NSCLC Adenocarcinoma

United States
Myriad Genetic Laboratories, Inc.

Withdrawn

Endometriosis Biomarker Discovery Study (EMBARK)

Endometriosis | Chronic Pelvic Pain

Clinical Trials Sponsored by Genetics Institute

Sponsors and Collaborators

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