Clinical Trials Sponsored by Horng Chen

Total 4731 results

LG Chem

Completed

A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia

Hyperuricemia | Gout

United States
LG Chem

Completed

Thorough QT (TQT) Study to Evaluate the Effect of LC350189 on Cardiac Repolarization in Healthy Male and Female Subjects

Hyperuricemia | Gout | Qt Interval, Variation in

United States
LG Chem

Completed

Relative Bioavailability Study to Assess an LC350189 Tablet Compared to an LC350189 Capsule in Healthy Adults

Hyperuricemia | Gout

United States
LG Chem

Active, not recruiting

A Phase I Clinical Trial to Investigate the Safety, Tolerability, and Pharmacokinetic Characteristics of TT-01025-CL in Healthy Subjects

Healthy

United States
LG Chem

Withdrawn

Efficacy and Safety of LC51-0255 in Subjects With Ulcerative Colitis

Ulcerative Colitis
LG Chem

Completed

Bioequivalence Study for Fixed Dose Combination Zemimet® SR Tab. 50/1000 and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

Type 2 Diabetes

Thailand
LG Chem

Completed

Compare the Pharmacokinetics, Pharmacodynamics and Safety/Tolerability of LC51-0255 Film-coated Tablet (SG85) With LC51-0255 Uncoated Tablet (SG82) in Healthy Subjects

Ulcerative Colitis

Korea, Republic of
LG Chem

Completed

An Ascending Dose, Single/Multiple Dosing, Food Effect Clinical Trial to Evaluate Pharmacokinetics, Safety and Tolerability in Healthy Subjects After Oral Administration of Gemigliptin (Phase I)

Type 2 Diabetes Mellitus

China
LG Chem

Unknown

A Study to Evaluate the Efficacy and Safety of Dual add-on Therapy With Gemigliptin 50 mg and Dapagliflozin 10 mg Added to Metformin Who Have Inadequate Glycemic Control on Metformin Alone

Diabetes Mellitus, Type 2
LG Chem

Unknown

Safety and Immunogenicity of Hexavalent Vaccine(DTwP-HepB-IPV-Hib) in Healthy Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type b Infection
LG Chem

Unknown

A Phase IV Study to Assess the Safety of EupentaTM Inj

Hepatitis B | Pertussis | Tetanus | Diphtheria | Haemophilus Influenzae Type B Infection
LG Chem

Unknown

BE Study of Bilayer Combination of Gemigliptin/Rosuvastatin 50/20mg in Comparison to Monolayer Combination.

Diabetes Mellitus, Type 2 | Dyslipidemias
LG Chem

Unknown

Relative Bioavailability Among Different Eutropin Formulations

Relative Bioavailability

Korea, Republic of
Lin Chen

Recruiting

Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric Cancer

Efficacy | Safety | HER2 Negative | Locally Advanced Gastric Carcinoma

China
Xiaoxiang Chen

Not yet recruiting

Homologous Recombination Deficiency in Chinese Ovarian Cancer Patients (HOPEI)

Ovarian Cancer | HRD | PARP Inhibitor

China
Lin Chen

Completed

Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes

Sepsis | Cytokine Storm | Sympathetic Nervous System Diseases | Catecholamine; Overproduction | Immunologic Paralysis | Lymphocyte Disorder T | Beta-Blocker

China
Jiaxiang Chen

Enrolling by invitation

The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery (PEEP)

Surgery | Anesthesia

China
Wen-huo Chen

Completed

Endovascular Treatment for AIS in Chinese Municipal and County Hospitals： A "Real World" Study-ETERNITY Registry

Endovascular Treatment

China
Lin Chen

Completed

Prospectively Predict the Immunotherapy Response of Gastric Cancer Based on Circulating Exosomal LncRNA-GC1 Biopsy

Immunotherapy | Advanced Gastric Carcinoma

China
Xiaoxiang Chen

Unknown

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer (AVANIRA3)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Endocrine System Diseases | Ovarian Diseases | Adnexal Diseases | Gonadal Disorders | Endocrine Gland Neoplasms | Ovarian Neoplasms | Fallopian Tube Neoplasms and other conditions

China
Jiarong Chen, MD

Unknown

The Association of hsCRP and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma

Head and Neck Cancer | Nasopharyngeal Carcinoma | Toxicity Due to Radiotherapy
Chen Chunlin

Unknown

Nerve Sparing Radical Hysterectomy VS Radical Hysterectomy: Safety and Clinical Efficacy

Cervical Cancer

China
Xiaolin Chen, MD

Recruiting

Shuxuening Injection for the Prevention of CVS in Patients With aSAH(SXN-CVS) (SXN-CVS)

Subarachnoid Hemorrhage, Aneurysmal

China
Chuangzhen Chen

Recruiting

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid Tumors (ILDRV1)

Radiotherapy | Immune Checkpoint Blockade | Metastatic Extracranial Malignant Solid Neoplasm | Resistance to Immunotherapy

China
Chuangzhen Chen

Recruiting

Study of Neoadjuvant Chemotherapy Versus Definite Concurrent Chemoradiotherapy for Locally Advanced Bulk Cervical Cancer

Cervical Cancer | Neoadjuvant Chemotherapy

China
Xiaoxiang Chen

Not yet recruiting

Variance of HRD From Paired Ovarian Cancer (HOPEII)

Ovarian Cancer | HRD | Platinum-sensitive Ovarian Cancer

China
Xiaoxiang Chen

Recruiting

The Clinical Markers for PARP Inhibitors-related Efficacy in Ovarian Cancer (ROMP)

Ovarian Cancer | PARP Inhibitor | Clinical Marker

China
Xiaoxiang Chen

Recruiting

Anlotinib Combined With Dose-reduced Olaparib in Patients With Platinum-Sensitive Recurrent Ovarian Cancer (ANLOLA)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Ovarian Diseases | Adnexal Diseases | Carcinoma, Ovarian Epithelial | Ovarian Cancer | Angiogenesis | Genital Diseases, Female | Antineoplastic Agents | BRCA1... and other conditions

China
Lin Chen

Completed

Risk of Aspergillus Infection in Patients With Chronic Lung Disease

Fungal Infection Lungs

China
Chen Ying

Enrolling by invitation

Efficacy of Anisodamine Hydrobromide Combined With Low-molecular-weight Heparin in the Treatment of Patients With Sepsis

Sepsis

China
Jiaxiang Chen

Active, not recruiting

Effect of Different Administrations of Propofol on Emergence Agitation in Preschool Children Undergoing Ambulatory Surgery

Surgery | Anesthesia

China
Jiarong Chen, MD

Unknown

Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients

Pain | Head and Neck Cancer | Nasopharyngeal Carcinoma | Radiation Induced Oral Mucositis
San Ni Chen

Completed

Internal Limiting Membrane Flap in the Management of Retinal Detachment Due to Paracentral Retinal Breaks

Surgery | Retinal Detachment
Chen Li Tien

Completed

Effect of Tai Chi on Functional Fitness of Elderly Patients With Degenerative Arthritis

Exercise Training

Taiwan
Sung-Chen Liu
Mackay Memorial Hospital

Completed

Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea (JAS)

Type 2 Diabetes

Taiwan
LG Chem

Not yet recruiting

Study to Evaluate LB-LR1109 for the Treatment of Solid Tumors (LB-LR1109)

Urothelial Carcinoma | Malignant Melanoma | Non-small Cell Lung Cancer(NSCLC) | Head and Neck Squamous Cell Carcinoma(HNSCC) | Renal Cell Carcinoma(RCC)
LG Chem

Recruiting

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients (EURELIA2)

Hyperuricemia | Gout | Gout Flare | Tophi

United States
LG Chem

Not yet recruiting

Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series

Hepatitis B | Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type B Infection
LG Chem

Not yet recruiting

Food-effect Bioavailability of Gemigliptin and Dapagliflozin 50/10 mg

Healthy Volunteers
LG Chem

Completed

A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of LG00034053 in Patients With Knee OA

Osteoarthritis, Knee

Korea, Republic of, Australia
LG Chem

Completed

A Study of LC542019 in Healthy Subjects and Subjects With T2DM

Healthy | Diabetes Mellitus, Type 2

United States
LG Chem

Completed

A Randomized, Multicenter, Evaluator-Blinded, Active-Controlled, Parallel-Group Investigation to Evaluate the Performance and Safety of YVOIRE® Classic Plus Versus Comparator for Temporary Correction of Nasolabial Folds

Correction of Nasolabial Folds

Germany
LG Chem

Completed

To Assess the Safety and Effectiveness of Hyruan ONE Versus a Comparator for the Treatment of Knee Osteoarthritis in Europe

Osteoarthritis (OA) of the Knee

Poland
LG Chem

Active, not recruiting

To Evaluate the Performance and Safety of YVOIRE Volume Plus for Improvement of Mid-face Volume

Midface Volume Deficit

Germany
LG Chem

Completed

Renal PK Study of LC350189

Hyperuricemia | Gout

United States
LG Chem

Unknown

Clinical Trial to Compare the PK of the Fixed-dose Combinations and Each Component of Gemigliptin/Dapagliflozin 50/10 mg

T2DM
LG Chem

Completed

Mass Balance Study of [14C]LC350189 in Healthy Volunteers

Hyperuricemia | Gout

United States
LG Chem

Completed

A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults

Hepatitis B | Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type b Infection

Korea, Republic of
LG Chem

Unknown

Food-effect Bioavailability of Fixed Dose Combination Zemimet® SR Tab. 50/1000 mg Under Fed and Fasting Conditions

Type2 Diabetes
LG Chem

Unknown

Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

Type2 Diabetes

3

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