Clinical Trials Sponsored by ICON plc

Total 11517 results

MorphoSys AG
ICON Clinical Research

Active, not recruiting

A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) (B-MIND)

Diffuse Large B-cell Lymphoma

United States, Hungary, Italy, Poland, Spain, Czechia, Germany, Australia, Austria, Canada, Croatia, Finland, France, Israel, Korea, Republic of, New Zealand, Portugal, Romania, Serbia, Singapore, Taiwan, Turkey, United Kingdom
Actinogen Medical
ICON Clinical Research

Completed

A Phase II Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in Subjects With Mild Dementia Due to AD (XanADu) (XanADu)

Dementia, Alzheimer Type

United States, Australia, United Kingdom
Arrowhead Pharmaceuticals
ICON Clinical Research

Terminated

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Hong Kong
GE Healthcare
ICON Clinical Research

Completed

Evaluate Effect of Optison on Pulmonary Artery Systolic Pressure (PASP) and Pulmonary Vascular Resistance (PVR).

Pulmonary Hypertension

United States
Cassiopea SpA
ICON Clinical Research; Canfield Scientific Inc.; Ergomed PLC; Pharmapace Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP2) (SCALP2)

Alopecia, Androgenetic

Germany, United States, Poland
Cassiopea SpA
ICON Clinical Research; Canfield Scientific Inc.; Ergomed PLC; Pharmapace Inc

Recruiting

A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP1)

Alopecia, Androgenetic

United States, Georgia
Ixchelsis Limited
HealthCore-NERI; Novotech (Australia) Pty Limited; ICON plc; PHT Corporation

Completed

IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT) and Patient Reported Outcomes in Men With Premature Ejaculation (PE)

Premature Ejaculation

United States, Australia
ICOS Corporation

Completed

A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis

Pneumonia | Sepsis

United States
Xencor, Inc.
ICON Clinical Research

Completed

PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies

Acute Myelogenous Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | B-cell Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia, Blast Crisis

United States
DiaSorin Inc.
ICON Clinical Research

Completed

Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects

Nausea | Abdominal Pain | Weight Loss | Helicobacter Pylori Infection | Gastric Ulcer | Stomach Ulcer | Loss of Appetite | Bloating

United States, Italy
Tsumura USA
ICON Clinical Research

Completed

A Safety and Efficacy Study of Daikenchuto (TU-100) to Relieve Abdominal Bloating in Female Subjects With Irritable Bowel Syndrome

Irritable Bowel Syndrome in Females

United States
Noscira SA
ICON Clinical Research

Completed

Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients (ARGO)

Alzheimer's Disease

Belgium, Finland, France, Germany, Spain, United Kingdom
AC Immune SA
ICON Clinical Research

Recruiting

A Study to Evaluate the Effects of ACI-7104.056 Vaccination in Patients With Early Stages of Parkinson's Disease (VacSYn)

Parkinson Disease | Parkinson Disease 6, Early-Onset

United Kingdom, Spain, Germany
Helsinn Healthcare SA
ICON Clinical Research

Recruiting

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities ((MARGARET))

RET-altered Solid Tumors | RET-altered Non Small Cell Lung Cancer

United States, Japan
Stealth BioTherapeutics Inc.
ICON Clinical Research

Completed

Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events (EMBRACE)

Reperfusion Injury | STEMI

United States, Hungary, Germany, Poland
Biomedical Advanced Research and Development Authority
Rho Federal Systems Division, Inc.; ICON plc

Recruiting

Anthrax AV7909 Boost Evaluation Study (ABESt)

Anthrax

United States
Elahi, Dariush, PhD
Massachusetts General Hospital; National Institute on Aging (NIA); ICON plc

Unknown

The Effect of VTC-G15 (a Pentapeptide Cleavage Product og GLP-1) on Whole Body Glucose Metabolism in Man (LVKGR)

Insulin Resistance

United States
ICOS Corporation

Completed

Interstitial Cystitis

Interstitial Cystitis

United States
Akros Pharma Inc.
ICON Clinical Research

Recruiting

Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction (POWER-HF)

Chronic Heart Failure

United States
Icon Genetics GmbH
University Hospital, Ghent

Completed

Recombinant, Bivalent, Norovirus Vaccine Study

Norovirus

Belgium
Bristol-Myers Squibb
ICON Clinical Research

Completed

Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting (SIMPLICITY)

Chronic Myeloid Leukemia

Germany, United States, Italy, Spain, France, Netherlands, Puerto Rico, Russian Federation
Boston Scientific Corporation
ICON Clinical Research

Completed

Heart Failure and Sudden Cardiac Death Japan Registry (HINODE)

Heart Failure | Arrhythmias, Cardiac | Sudden Cardiac Death

Japan
Golden Biotechnology Corporation
ICON Clinical Research

Completed

Efficacy, Safety and Pharmacokinetics Study of Antroquinonol to Treat NSCLC

Non-small Cell Lung Cancer Stage IV

United States, Taiwan
Bühlmann Laboratories AG
ICON Clinical Research

Completed

BÜHLMANN fCAL™ ELISA - Aid in Differentiation of IBD From IBS

Irritable Bowel Syndrome | Inflammatory Bowel Disease

United States
Celgene Corporation
ICON Clinical Research

Completed

Lenalidomide Versus Placebo in Myelodysplastic Syndromes With a Deletion 5q[31] Abnormality

Myelodysplastic Syndromes

Germany, Israel, United Kingdom, Spain, Belgium, Italy, France, Netherlands, Sweden
Newron Sweden AB
Medtronic; ICON Clinical Research

Completed

A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Belgium
ICOS-Texas Biotechnology
ICOS Corporation; Texas Biotechnology Corporation

Unknown

Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States, Canada
MEDA Pharma GmbH & Co. KG
ICON plc; Clinipace Worldwide; Trium Analysis Online GmbH

Terminated

Tepilta® Versus Oxetacaine, Antacids and Placebo

Radiation-induced Oesophagitis

Germany, Austria
Ocon Medical Ltd.

Recruiting

IUB SEAD RED (Revolutionary Endometrial Ablation Device Study) (HMB)

Heavy Menstrual Bleeding

Israel
Ocon Medical Ltd.

Completed

A Study to Evaluate the Safety and Initial Efficacy of a Novel Intrauterine Device

Contraception

Hungary
Ocon Medical Ltd.

Withdrawn

A Study on the Safety and Efficacy of the SCu300A IUB Compared to the TCu380 Copper IUD

Reversible Prevention of Pregnancy

Israel
Biotest
Accovion GmbH; ICON plc; SYNLAB Analytics and Services Germany GmbH; Phoenix Clinical... and other collaborators

Completed

Pharmacokinetic, Efficacy and Safety of BT524 in Patients With Congenital Fibrinogen Deficiency

Congenital Afibrinogenemia | Congenital Hypofibrinogenemia

Bulgaria, Egypt, Germany, Lebanon, Tunisia
EVP Eye Care
Alcon Research; Icon Eye Care

Terminated

Visual Outcomes After Vivity Toric IOL Implantation

Refractive Assessment

United States
Vifor Pharma
ICON Clinical Research; American Regent, Inc.

Completed

Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD) (FIND-CKD)

Chronic Kidney Disease | Iron Deficiency Anaemia

United Kingdom, United States, Australia, Austria, Belgium, Czech Republic, Denmark, France, Germany, Greece, Italy, Netherlands, Norway, Poland, Portugal, Romania, Spain, Sweden, Turkey
RAI Services Company
ICON Clinical Research Limited

Completed

CSD1805: Study to Assess Nicotine Uptake and Product Use Behavior in Moist Snuff Consumers Using Two Moist Snuff Products

Tobacco Use

United States
Newron Sweden AB
Medtronic; ICON Clinical Research

Terminated

An Open Label, Safety and Tolerability Continuation Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Belgium
Ocon Medical Ltd.

Recruiting

IUB SEAD RED (Revolutionary Endometrial Ablation Device Study (HMB)

Heavy Menstrual Bleeding

Israel, Georgia
Ocon Medical Ltd.

Completed

Study to Assess the Safety and Efficacy of the IUB SEAD™ Device (AUB)

Abnormal Uterine Bleeding

Bulgaria
Ocon Medical Ltd.

Completed

IUB(TM) SCu300B - Post Marketing Performance Study in Austria

Contraception
Ocon Medical Ltd.

Completed

Multivariate Assessment of the IUB Intrauterine Device Compared With a T380A IUD

To Assess the Safety, Effectiveness and User Experience of the Scu 300A IUB

Bulgaria, Romania
IBON JAUNARENA

Completed

Efficacy of a Fibrin Sealant for the Prevention of Lymphocele After Lymphadenectomy

Lymphocele
ICOS Corporation
Suntory Pharmaceutical

Terminated

Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis

Sepsis

United States
Green Cross Corporation
ICON Clinical Research

Terminated

Safety Study of MG1102 in Patients With Solid Tumors

Solid Tumors

Korea, Republic of
Emalex Biosciences Inc.
ICON Early Phase Services; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport

Drug Interaction

United States
Enanta Pharmaceuticals, Inc
ICON Clinical Research; Triangle Biostatistics

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis

Non-Alcoholic Steatohepatitis

United States, United Kingdom, New Zealand, Canada, France, Puerto Rico
University of Illinois at Chicago
ICON Bioscience Inc

Completed

20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) (20089/Combo)

Age-Related Macular Degeneration | Choroidal Neovascularization

United States
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
iCo Therapeutics Inc.

Completed

Safety Study of iCo-007 Intravitreal Injection to Treat Diabetic Macular Edema

Diffuse Diabetic Macular Edema

United States
Iron Horse Diagnostics, Inc.

Unknown

A Study to Evaluate the Performance of a Diagnostic Test in ALS

Amyotrophic Lateral Sclerosis (ALS)

United States
Pine Trees, Inc.
Piedmont Healthcare; ICON plc; MRI Global; ASCLEPES Research Center; Eastside Research... and other collaborators

Completed

A Clinical Evaluation of Pine Trees Health Test System Including the Pine Trees Health Reader and COVID-19 Test for Point-of-Care

Covid19 | SARS (Severe Acute Respiratory Syndrome)

United States

Clinical Trials Sponsored by ICON plc

Sponsors and Collaborators

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