Clinical Trials Sponsored by ICONA Cohort

Total 238 results

Amsterdam Molecular Therapeutics
ICON plc

Terminated

Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies

Hyperlipoproteinemia Type I

Canada
Vifor Pharma
ICON Clinical Research

Completed

A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency (CONFIRM-HF)

Chronic Heart Failure | Iron Deficiency

Poland, Russian Federation
PENTA Foundation
Karolinska Institutet; Centre Hospitalier Universitaire Saint Pierre; Centro... and other collaborators

Active, not recruiting

European Pregnancy and Paediatric Infections Cohort Collaboration: Paediatric Protocol (EPPICC)

HIV Infections | Covid19 | Hepatitis C | Tuberculosis Infection
Chiesi Farmaceutici S.p.A.
ICON plc

Not yet recruiting

A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease (FLY)

Fabry Disease
Immorna Biotherapeutics, Inc.
ICON plc

Recruiting

A Phase 1/2 Study to Assess the Safety and Immunogenicity of JCXH-221, an mRNA-based Broadly Protective COVID-19 Vaccine

COVID-19 | Infectious Disease

United States
Immorna Biotherapeutics, Inc.
ICON plc

Active, not recruiting

A First-in-Human Study to Evaluate JCXH-105, an srRNA-based Herpes Zoster Vaccine (JCXH-105)

Infectious Disease | Shingles | Herpes Zoster (HZ)

United States
Adient Medical
ICON plc; Avania

Active, not recruiting

US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism

Pulmonary Embolism

United States
Xencor, Inc.
ICON Clinical Research

Completed

PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies

Acute Myelogenous Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | B-cell Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia, Blast Crisis

United States
DiaSorin Inc.
ICON Clinical Research

Completed

Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects

Nausea | Abdominal Pain | Weight Loss | Helicobacter Pylori Infection | Gastric Ulcer | Stomach Ulcer | Loss of Appetite | Bloating

United States, Italy
Xencor, Inc.
PPD; ICON plc

Completed

A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Carnegie Mellon University
ICON plc

Completed

Informed Consent Formats by Information Preference and Priority

Asthma | Consent Forms

United States
Tsumura USA
ICON Clinical Research

Completed

A Safety and Efficacy Study of Daikenchuto (TU-100) to Relieve Abdominal Bloating in Female Subjects With Irritable Bowel Syndrome

Irritable Bowel Syndrome in Females

United States
Noscira SA
ICON Clinical Research

Completed

Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients (ARGO)

Alzheimer's Disease

Belgium, Finland, France, Germany, Spain, United Kingdom
The HIV Netherlands Australia Thailand Research...
National Health Security Office, Thailand; Swiss HIV Cohort Study

Completed

Second-line Therapy Antiretroviral in Patients Who Failed Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) - Based Regimens

HIV Infections

Thailand
AC Immune SA
ICON Clinical Research

Recruiting

A Study to Evaluate the Effects of ACI-7104.056 Vaccination in Patients With Early Stages of Parkinson's Disease (VacSYn)

Parkinson Disease | Parkinson Disease 6, Early-Onset

United Kingdom, Spain, Germany
Helsinn Healthcare SA
ICON Clinical Research

Recruiting

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities ((MARGARET))

RET-altered Solid Tumors | RET-altered Non Small Cell Lung Cancer

United States, Japan
HighLife SAS
MedPass International; ICON plc

Active, not recruiting

HighLife™ Transcatheter Mitral Valve Replacement System Study

Mitral Valve Insufficiency | Mitral Valve Regurgitation

France, Germany
Omron Healthcare Co., Ltd.
ICON plc

Completed

Evaluation of Blood Pressure Monitor With AFib Screening Feature

Atrial Fibrillation

United States
BeyondSpring Pharmaceuticals Inc.
Covance; ICON plc

Completed

Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 3 (Protective-1)

Chemotherapy-induced Neutropenia

China, Russian Federation, United States, Ukraine
Stealth BioTherapeutics Inc.
ICON Clinical Research

Completed

Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events (EMBRACE)

Reperfusion Injury | STEMI

United States, Hungary, Germany, Poland
Hospital Sultanah Aminah Johor Bahru

Completed

Optimal Relaxation Technique for Laparotomies With Rocuronium Infusion Followed by Sugammadex Reversal (ProjectO5Rs)

Underdosing of Skeletal Muscle Relaxants for Laparotomy | Reversal of Skeletal Muscle Relaxant

Malaysia
Hospital Sultanah Aminah Johor Bahru

Unknown

Vigileo FloTrac vs Pulmonary Artery Catheter

Ischemic Heart Disease | Valvular Heart Disease

Malaysia
National Cancer Institute (NCI)
Multicenter Hemophilia Cohort Study

Completed

The Second Multicenter Hemophilia Cohort Study

Hepatocellular Carcinoma | Non-Hodgkin Lymphoma | Liver Decompensation

United States, Germany, Italy, Brazil, Canada, France, Greece, Sweden
Boston Children's Hospital
Boston Children's Hospital - Children's Rare Disease Cohorts Initiative

Recruiting

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Movement Disorders | Neurodegenerative Diseases | Motor Neuron Disease | Spasticity, Muscle | Pediatric Disorder | Hereditary Spastic Paraplegia

United States
Steba Biotech S.A.
PrimeVigilance; ICON plc

Recruiting

ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study (UCM301)

Transitional Cell Cancer of Renal Pelvis and Ureter

United States, Israel, Spain, Italy, France, Germany, Austria
Effector Therapeutics
Medpace, Inc.; ICON plc

Active, not recruiting

Tomivosertib Combined With Pembrolizumab in Subjects With PD-L1 Positive NSCLC (KICKSTART) (KICKSTART)

Non-small Cell Lung Cancer

United States, Australia, Georgia
Westfälische Wilhelms-Universität Münster
ICON plc

Unknown

Natural History of GACI With or Without ARHR2 or PXE

Pseudoxanthoma Elasticum | Generalized Arterial Calcification in Infancy | Autosomal Recessive Hypophosphatemic Rickets

Germany
Lytix Biopharma AS
ICON plc; Theradex

Completed

LTX-315 in Patients With Transdermally Accessible Tumours as Monotherapy or Combination With Ipilimumab or Pembrolizumab

Melanoma | Lymphoma | Cancer | Breast Cancer | Head and Neck Cancer | Triple-Negative Breast Cancer

United Kingdom, France, Norway, Belgium, Italy
University Hospital, Bonn
King's College London; Hospital General Universitario Gregorio Marañon; University... and other collaborators

Recruiting

HDV-Europe: Prevalence and Outcome of HDV in HIV/HBV Coinfection

Hepatitis D

Germany
Centre Hospitalier Universitaire de Nīmes
Annie Bauer Confort

Withdrawn

Comparison of 2 Mattresses for the Prevention of Bedsores by Measuring Skin Pressure in the Sacral Area (SPA2-ARSFT-DUO)

Pressure Ulcer

France
National Cancer Institute (NCI)
Multicenter AIDS Cohort Study (MACS)

Completed

Genetics of Progressive Multifocal Leukoencephalopathy and Acquired Immunodeficiency Syndrome

AIDS | PML

United States
Akros Pharma Inc.
ICON Clinical Research

Recruiting

Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction (POWER-HF)

Chronic Heart Failure

United States
Thermo Fisher Scientific Oy
ICON plc

Completed

Stability of Tacrolimus, Cyclosporine A, Everolimus and Sirolimus in Whole Blood Patient Samples

Transplantation Drugs Stability

Italy
Icon Genetics GmbH
University Hospital, Ghent

Completed

Recombinant, Bivalent, Norovirus Vaccine Study

Norovirus

Belgium
H. Lundbeck A/S
ICON plc

Completed

Vortioxetine in Patients With Depression and Early Dementia (MEMORY)

Dementia | Major Depressive Disorder

Korea, Republic of, Spain, Poland, Estonia, France, Italy
Bristol-Myers Squibb
ICON Clinical Research

Completed

Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting (SIMPLICITY)

Chronic Myeloid Leukemia

Germany, United States, Italy, Spain, France, Netherlands, Puerto Rico, Russian Federation
Boston Scientific Corporation
ICON Clinical Research

Completed

Heart Failure and Sudden Cardiac Death Japan Registry (HINODE)

Heart Failure | Arrhythmias, Cardiac | Sudden Cardiac Death

Japan
Danisco
ICON plc; 4Pharma Ltd.; Daacro

Completed

A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress

Healthy | Stress, Psychological

Ireland, United Kingdom
Golden Biotechnology Corporation
ICON Clinical Research

Completed

Efficacy, Safety and Pharmacokinetics Study of Antroquinonol to Treat NSCLC

Non-small Cell Lung Cancer Stage IV

United States, Taiwan
Bühlmann Laboratories AG
ICON Clinical Research

Completed

BÜHLMANN fCAL™ ELISA - Aid in Differentiation of IBD From IBS

Irritable Bowel Syndrome | Inflammatory Bowel Disease

United States
AstraZeneca
Covance; ICON plc; PHT Corporation

Terminated

Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Celgene Corporation
ICON Clinical Research

Completed

Lenalidomide Versus Placebo in Myelodysplastic Syndromes With a Deletion 5q[31] Abnormality

Myelodysplastic Syndromes

Germany, Israel, United Kingdom, Spain, Belgium, Italy, France, Netherlands, Sweden
MedRegen LLC
Johns Hopkins University; ICON plc

Recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients

COVID-19 | ARDS, Human | Regeneration | Stem Cells

United States
Resverlogix Corp
PPD; ICON plc; Medidata Solutions

Completed

Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD (BETonMACE)

Coronary Artery Disease | Diabetes Mellitus, Type 2

Netherlands, Taiwan, Argentina, Israel, Poland, Russian Federation, Australia, Belgium, Serbia, Bulgaria, Hungary, Slovakia, Mexico, Croatia, Germany
Newron Sweden AB
Medtronic; ICON Clinical Research

Completed

A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Belgium
PROspective Renal Cancer Cohort Foundation
Bristol-Myers Squibb; Merck Sharp & Dohme LLC; Ipsen; Comprehensive Cancer Centre...

Recruiting

National PROspective Infrastructure for Renal Cell Carcinoma (PRO-RCC) (PRO-RCC)

Renal Cell Carcinoma | Renal Cancer | Renal Cell Cancer Metastatic

Netherlands
Conor Kerley

Completed

Trial of Vitamin D3 Supplementation in Paediatric Asthma (NCHVitDAst)

Asthma
Ilona C Narayen, MD pHD

Not yet recruiting

Baby Sickness Evaluation (BeSurE)

Infant, Newborn, Diseases
Vaxess Technologies
ICON plc; Q2 Solutions; Centricity Research

Completed

Phase 1 Evaluation of H1 Influenza Vaccine Delivered by MIMIX MAP

Influenza

Canada
RAI Services Company
ICON Clinical Research Limited

Completed

CSD1805: Study to Assess Nicotine Uptake and Product Use Behavior in Moist Snuff Consumers Using Two Moist Snuff Products

Tobacco Use

United States

Clinical Trials Sponsored by ICONA Cohort

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hong Kong

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations