Clinical Trials Sponsored by Indiana Clinical and Translational Sciences Institute

Total 795 results

Oregon Health and Science University
Oregon Clinical and Translational Research Institute; Pulsion Medical Systems

Completed

Hemodynamics and Extravascular Lung Water in Acute Lung Injury (HEAL)

Acute Lung Injury

United States
Susan J. Hayflick
Oregon Health and Science University; Oregon Clinical and Translational Research...

Completed

Brain Perfusion in Pantothenate Kinase-associated Neurodegeneration (PKAN)

Pantothenate Kinase-associated Neurodegeneration (PKAN)

United States
Oregon Health and Science University
University of California, Davis; National Center for Advancing Translational... and other collaborators

Not yet recruiting

Efficacy of a Multimodal Brain Health Intervention for Older African Americans (SHARP)

Cognitive Decline | Cognitive Impairment, Mild
Pennington Biomedical Research Center
Louisiana Clinical and Translational Science Center

Terminated

The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause (RESUME)

Adiposity | Menopause Surgical | Estrogen Deficiency

United States
Mayo Clinic
Mayo Clinic Clinic Center for Innovation; Mayo Clinic Center for Clinical and...

Completed

Cardiovascular Health Promotion Among African-Americans by FAITH! (FAITH!)

Cardiovascular Diseases | Smoking Cessation | Hypertension | Obesity | Diabetes | Physical Activity | Diet Modification | Pre Diabetes | Prevention | High Cholesterol
University of Colorado, Denver
National Cancer Institute (NCI); National Center for Advancing Translational... and other collaborators

Completed

Appetite and Exercise in Breast Cancer Survivors (EARNESt)

Obesity | Breast Cancer | Overweight

United States
Todd Schroeder
Southern California Clinical and Translational Science Institute

Completed

Resistance Training and Neuroimaging (RTNI)

Cognitive Decline | Cerebrovascular Function

United States
UNC Lineberger Comprehensive Cancer Center
UNC Translational and Clinical Sciences (Tracs)

Completed

Retinal Oxygen Function After Radiation Therapy

A History of Radiation Therapy for a Tumor in the Vicinity of the Retina(s)

United States
Michael Kyle Ritchie
West Virginia Clinical and Translational Science Institute

Completed

Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)

Cardiac Arrest | Circulatory Failure

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Active, not recruiting

MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus (MERMAID-T1D)

Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Diabetes Mellitus Complication | Metabolic Disease | Type1 Diabetes Mellitus | Autoimmune Diabetes | Juvenile Diabetes

United States
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); Oregon Clinical and Translational...

Completed

Spironolactone in Adult Congenital Heart Disease

Heart Failure | Congenital Heart Disease | Endomyocardial Fibrosis

United States
University of Colorado, Denver
National Cancer Institute (NCI); Colorado Clinical & Translational Sciences...

Terminated

Combined Modality Exercise and Appetite in Breast Cancer Survivors (CARE)

Overweight and Obesity | Breast Cancer Female

United States
University of Iowa
Osseointegration Foundation; University of Iowa Institute of Clinical and Translational...

Completed

The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study

Obesity | Peri-implant Inflammation | Peri-implantitis

United States
Medical College of Wisconsin
Clinical & Translational Science Institute of Southeast Wisconsin

Completed

Effect of Curcumin on Gut Microbiota in IBS

Irritable Bowel Syndrome

United States
Franziska Wachter
Harvard Clinical and Translational Science Center (Harvard Catalyst)

Recruiting

A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies (MORE)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | MDS | Aml | Myeloid Neoplasm | Myeloid Malignancies | Inherited Bone Marrow Failure Syndrome

United States
Tulane University
Louisiana Clinical and Translational Science (LA CaTS) Center Clinical Research...

Completed

Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial Fibrillation Patients and Controls

Atrial Fibrillation | Arrhythmia

United States
University of North Carolina, Chapel Hill
Metagenics, Inc.; North Carolina Translational and Clinical Sciences Institute

Completed

Bioavailability of SPMs in Obese Humans

Obesity Adult Onset

United States
University of North Carolina, Chapel Hill
RTI International; North Carolina Translational and Clinical Sciences Institute

Completed

Patient and Family Partners in Heart Failure Care: Pilot Test of a Pre-visit Question Prompt List to Enhance Engagement During Medical Visits

Heart Failure

United States
University of North Carolina, Chapel Hill
Vanderbilt University; North Carolina Translational and Clinical Sciences Institute

Completed

Contrast-enhanced Ultrasound of the Kidney (CEUS-CKD)

Chronic Kidney Disease | Cystic Kidney Disease

United States
Indian Institute of Science
Wellcome Trust; PATH; University of Liverpool; National Institute of Mental Health...

Completed

A Prospective, Open Label Study of Human T Cell Responses to Live Attenuated Japanese Encephalitis Vaccine SA14-14-2

Japanese Encephalitis | Japanese Encephalitis Vaccine

India
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute; XinVivo, Inc.

Completed

Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study

Dental Caries

United States
University of Colorado, Denver
Cystic Fibrosis Foundation; Colorado Clinical & Translational Sciences Institute

Completed

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

Cystic Fibrosis

United States
Clinical and Translational Genome Research Institute...
Children's Specialized Hospital

Terminated

Pharmacogenomics for Improving Pediatric ADHD Treatment

Attention Deficit Disorders With Hyperactivity

United States
Boston Medical Center
National Institute of Allergy and Infectious Diseases (NIAID); BU Clinical...

Completed

Coaching for HCV and HIV

HIV Infections | Hepatitis C | Opioid-use Disorder

United States
University of North Carolina, Chapel Hill
National Institutes of Health (NIH); North Carolina Translational and Clinical...

Completed

Cranial Laser Reflex Technique for Hamstring Function (CLRTHam)

Muscle Pain | Muscle Weakness | Muscle Tone Increased | Hamstring Injury

United States
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill; National Center for Advancing Translational... and other collaborators

Recruiting

Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study

Lynch Syndrome

United States
Washington University School of Medicine
Barnes-Jewish Hospital; Washington University Institute of Clinical and Translational...

Completed

Novel Approach To Improving Lactation Support With Mobile Health Technology

Feeding Behavior | Breastfeeding

United States
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function

Alcoholic Hepatitis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Incidence & Predictive Factors of Recompensation in Children With Decompensated Cirrhosis as Per the Baveno VII Criteria

Decompensated Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Effect of Consumption of Millet Diet in Patients With NAFLD

NAFLD

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF Patients

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Evaluation of Low-dose Albumin and Midodrine Versus Midodrine Alone in Outcome of Recurrent Ascites in Patients With Decompensated Cirrhosis.

Decompensated Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy and Safety of SBRT Combined With Atezolizumab Plus Bevacizumab vs Atezolizumab Plus Bevacizumab in Treating Unresectable Advance Hepatocellular Carcinoma.

Advanced Hepatocellular Carcinoma

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Rifaximin vs Norfloxacin for Secondary Prophylaxis of SBP (NORRIF Trial)

Spontaneous Bacterial Peritonitis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of 5% Albumin v/s Plasmalyte in Combination With 20% Albumin for Fluid Resuscitation in Cirrhosis With Sepsis Induced Hypotension

Liver Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Spleen Stiffness as a Measure to Assess the REsponse to β Blocker Therapy (SPARE-B)

High Risk Esophageal Varices

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Pentoxifylline Plus Carvedilol vs Carvedilol Monotherapy in Preventing New Decompensation in Stable Cirrhotic Patients With Prior Decompensation

Liver Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of High Dose Albumin Therapy in Improving Liver Transplant-free Survival in Patients With Acute Decompensation of Cirrhosis

Decompensated Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Recruiting

Acute Hemodynamic Response to Carvedilol in Children With Clinically Significant Portal Hypertension.

Portal Hypertension

India
Institute of Liver and Biliary Sciences, India

Recruiting

To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure Patients

Liver Cirrhosis | Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Recruiting

Platelet Augmentation Using C. Papaya Leaf Extract in Live Donor Liver Transplantation

Thrombocytopenia

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy and Safety of Vasopressin Versus Terlipressin as a Second Vasopressor in Critically Ill Cirrhotics With Septic Shock- the VITEL-C Trial

Septic Shock | Cirrhosis, Liver

India
Institute of Liver and Biliary Sciences, India

Recruiting

Fecal Microbiota Therapy in Steroid Ineligible Alcoholic Hepatitis

Alcoholic Hepatitis

India
Institute of Liver and Biliary Sciences, India

Recruiting

TAF (Tenofovir Alafenamide) for Preventing Progression of Liver Disease in Non-cirrhotic Chronic HBV Infection With Normal ALT and Low Viral Load.

Non-cirrhotic, Chronic Hepatitis B

India
Institute of Liver and Biliary Sciences, India

Recruiting

To Study the Safety and Efficacy of Simvastatin in Patients With Hepatopulmonary Syndrome in Cirrhosis.

Liver Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Comparative Efficacy of Various Non-invasive Methods in Assessing Response to Beta-blockers as Secondary Prophylaxis for Acute Variceal Bleed.

Acute Variceal Bleed

India
Institute of Liver and Biliary Sciences, India

Recruiting

Preoperative Sepsis Timeline, Profile and Its Association With Recipient Outcome Following Live Donor Liver Transplant

Sepsis | Liver Transplant; Complications

India
Institute of Liver and Biliary Sciences, India

Recruiting

Efficacy and Safety of Carvedilol in Cirrhosis Patients With Uncomplicated Ascites Without High Risk Esophageal Varices

Liver Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Evaluate the Safety and Efficacy of Preemptive Administration of Continuous Renal Replacement Therapy in Patients With Acute Liver Failure With Cerebral Edema

Acute Liver Failure

India

Clinical Trials Sponsored by Indiana Clinical and Translational Sciences Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Egypt

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations