Clinical Trials Sponsored by Istari Oncology, Inc.

Total 1026 results

Clovis Oncology, Inc.

Terminated

A Study to Assess the Safety and Efficacy of the VEGFR-FGFR-PDGFR Inhibitor, Lucitanib, Given to Patients With Metastatic Breast Cancer

Breast Cancer | Metastatic Breast Cancer | Estrogen Receptor Positive | Triple Negative | HER2 | HER2 Positive | MBC | ER

United States
Taiho Oncology, Inc.

Terminated

Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Taiho Oncology, Inc.

Terminated

An Investigation of TAS-119 Monotherapy

Advanced Solid Tumors

Italy, Spain, United States, Netherlands, United Kingdom
Taiho Oncology, Inc.

Completed

A Trial of TAS-114 in Combination With S-1

Advanced Solid Tumors

France, Belgium, Italy, Switzerland
Taiho Oncology, Inc.

Completed

A Study of TAS-116 in Patients With Solid Tumors

Advanced Solid Tumors

United States, United Kingdom, Italy
Clovis Oncology, Inc.

Completed

Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma

Metastatic Pancreatic Adenocarcinoma

United States
Sierra Oncology, Inc.

Terminated

Momelotinib Combined With Capecitabine and Oxaliplatin in Adults With Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma

Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma

United States
Sierra Oncology, Inc.

Terminated

Erlotinib and Momelotinib for the Treatment of Epidermal Growth Factor Receptor (EGFR) Mutated EGFR Tyrosine Kinase Inhibitor (TKI) Naive Metastatic Non-Small Cell Lung Cancer (NSCLC)

EGFR Mutated EGFR TKI Naive Metastatic NSCLC

United States
Sierra Oncology, Inc.

Completed

Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, Canada, Australia
Clovis Oncology, Inc.

No longer available

Rociletinib (CO-1686) USA Expanded Access Program

Non-small Cell Lung Cancer

United States
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.

Advanced Gastrointestinal Tumors

United States
Taiho Oncology, Inc.

Completed

Study to Evaluate the Cardiac Safety of TAS-102 in Patients With Advanced Solid Tumors

Advanced Solid Tumors (Excluding Breast Cancer)

United States
OvaGene Oncology, Inc.

Unknown

DNA Single Nucleotide Polymorphisms as Predictors of Toxicity

Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms

United States
Clovis Oncology, Inc.

Terminated

A Dose Ascending Study of Gemcitabine Elaidate (CO-101) in Combination With Cisplatin

Lung Cancer | Solid Tumor | Non-small-cell Lung Cancer

United States, United Kingdom
Taiho Oncology, Inc.

Completed

A Phase 1, Open-Label, Randomized, Cross-Over, Pharmacokinetic Study Evaluating the Effect of S-1 on Advanced Solid Tumors

Tumors

United States
Taiho Oncology, Inc.

Completed

Evaluating Patients With Impaired Hepatic Function

Impaired Hepatic Function

United States
Taiho Oncology, Inc.
Quintiles, Inc.

Terminated

Phase 2 Study of TAC-101 Combined With Transcatheter Arterial Chemoembolization (TACE) Versus TACE Alone in Japanese Patients With Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

Japan
Star Scientific, Inc

Completed

A Pilot Study to Evaluate the Efficacy and Safety of Ariva® Silver Wintergreen in Healthy Smokers

Smoking | Tobacco Use Disorder

United States
Taiho Oncology, Inc.
Quintiles, Inc.

Completed

Phase 2 Study of S-1 as 2nd Line Therapy in Metastatic Pancreatic Cancer

Secondary Malignant Neoplasm of Pancreas
Taiho Oncology, Inc.
Quintiles, Inc.

Terminated

Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy

Hepatocellular Carcinoma

Italy
Taiho Oncology, Inc.
Quintiles, Inc.

Completed

A Safety and Efficacy Study in Patients With Gastric Cancer

Gastric Cancer

United States, Canada
Clovis Oncology, Inc.
Genentech, Inc.

Terminated

A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC

Non-small Cell Lung Cancer

United States
Taiho Oncology, Inc.
Quintiles, Inc.

Completed

A Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With Capecitabine in Patients With Advanced Solid Tumors

Neoplasms

United States
Star Scientific, Inc

Completed

A Pilot Study to Evaluate the Efficacy of Ariva® Silver Wintergreen, a Smoking Aversive Lozenge

Smoking | Tobacco Use Disorder

United States
Star Scientific, Inc

Completed

Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers

Smoking | Tobacco Use Disorder

United States
PrimeVax Immuno-Oncology Inc.

Not yet recruiting

Arm 1: Lysate Pulsed Dendritic Cells (PV-001-DC) in Patients With Melanoma

Metastatic Melanoma
Prostate Oncology Specialists, Inc.

Completed

Sipuleucel-T and Ipilimumab for Advanced Prostate Cancer

Prostate Cancer | Castrate Resistant Prostate Cancer

United States
Vector Oncology
Eisai Inc.

Terminated

Study of Neoadjuvant Carboplatin, Eribulin and Trastuzumab for Operable HER2 Positive Breast Cancer

HER-2 Positive Breast Cancer

United States
Kura Oncology, Inc.
Mirati Therapeutics Inc.

Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors (FIT-001)

Non Small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC) | Clear Cell Renal Cell Carcinoma (ccRCC) | Solid Tumors With HRAS Alterations

United States
General Oncology, Inc.
Myriad Genetics, Inc.

Recruiting

SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | BRCA1 Mutation | BRCA2 Mutation | Pancreatic Acinar Cell Carcinoma | Metastatic Pancreatic Cancer | Breast Cancer Metastatic | HER2-negative Breast Cancer | Metastatic Pancreatic Ductal Adenocarcinoma and other conditions

United States
F-star Therapeutics, Inc.

Completed

A Study Evaluating the Safety, Pharmacokinetics, and Antiviral Efficacy of SB 9200 in Subjects Infected With Chronic HBV (ACHIEVE)

Hepatitis B | Hepatitis, Viral

Canada, Hong Kong, Korea, Republic of, Taiwan
Brown University
Taiho Oncology, Inc.

Recruiting

TAS-116 Plus Palbociclib in Breast and Rb-null Cancer

Soft Tissue Sarcoma | Advanced Breast Cancer | SCLC | Bladder Cancer | Endometrial Cancer | Treatment-Refractory Solid Tumors | Retinoblastoma Deficiency

United States
Jazz Pharmaceuticals
ALX Oncology Inc.

Active, not recruiting

A Study of Zanidatamab (ZW25) With Evorpacept (ALX148) in Patients With Advanced HER2-expressing Cancer

HER2-expressing Cancers

United States
Clovis Oncology, Inc.
Novartis Pharmaceuticals

Terminated

Phase 1/2 Study of the Safety and Efficacy of Rociletinib in Combination With Trametinib in Patients With mEGFR-positive Advanced or Metastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

United States
Gynecologic Oncology Associates
Genentech, Inc.

Completed

Pilot Study of Taxol, Carboplatin, and Bevacizumab in Advanced Stage Ovarian Carcinoma Patients

Ovarian Neoplasms

United States
Preventive Oncology International, Inc.
Imalux

Completed

Study of the Diagnostic Efficacy of "Real Time" Niris 1300e Optical Coherence Tomography (OCT) Imaging System in the Management of Pre-invasive and Invasive Neoplasia of the Uterine Cervix (PUSHOCTII)

Cervical Intraepithelial Neoplasia | Cervix Cancer | CIN | Human Papillomavirus | Cervical Dysplasia

China
Cullinan Oncology Inc.
Harbour BioMed US, Inc.

Recruiting

CLN-418 Study on Subjects With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
Institut Curie
Rain Oncology Inc

Terminated

Milademetan and Fulvestrant in GATA3-mutant, ER+HER- Advanced or Metastatic Breast Cancer (DEMETER)

Advanced or Metastatic Breast Cancer

France
US Oncology Research
Genentech, Inc.

Terminated

Phase 2 Study of Standard Chemotherapy With Trastuzumab, Plus or Minus Pertuzumab, for Pre-treated Metastatic Breast Cancer

Breast Neoplasms | Malignant Tumor of the Breast

United States
Tesaro, Inc.
Gynecologic Oncology Group

Terminated

Study to Evaluate the Efficacy and Safety of the Combination of Niraparib and Dostarlimab (TSR-042) in Participants With Platinum Resistant Ovarian Cancer (MOONSTONE)

Ovarian Neoplasms

United States
AbbVie
Sumitomo Pharma Oncology, Inc.

Completed

A Study of Venetoclax and Alvocidib in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

United States, Germany, United Kingdom
ImmunoGen, Inc.
Gynecologic Oncology Group

Completed

A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Women With Folate Receptor (FR) Alpha Positive Advanced Epithelial Ovarian Cancer (EOC), Primary Peritoneal or Fallopian Tube Cancer (FORWARD I)

Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States, France, Canada, Spain, Switzerland, Belgium, Italy, United Kingdom, Ireland, Russian Federation, Bosnia and Herzegovina, Czechia, Serbia
Concure Oncology-Breast Microseed Inc.

Recruiting

A Registry Study of Breast Microseed Treatment

Breast Neoplasms

United States
Advaxis, Inc.
Gynecologic Oncology Group

Terminated

Study of ADXS11-001 in Participants With High Risk Locally Advanced Cervical Cancer (AIM2CERV)

High Risk Cervical Cancer | Advanced Cervical Cancer

United States, Argentina, Brazil, Canada, Chile, Korea, Republic of, Malaysia, Mexico, Poland, Russian Federation, Serbia, Spain, Taiwan, Ukraine
Eisai Inc.
Children's Oncology Group

Completed

This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumors (Excluding [Central Nervous System] CNS), Including Lymphomas (BOLD 113)

Solid Tumors | Pediatrics

United States
US Oncology Research
Quintiles, Inc.

Completed

Biomarker Analysis for Patients With Metastatic Colorectal Cancer (MCC)

Colorectal Neoplasms | Advanced Metastatic Colorectal Cancer

United States
Taiho Oncology, Inc.
Quintiles, Inc.; United BioSource, LLC

Completed

Phase 2 Study of S-1 as 2nd Line Therapy in Advanced Non-Small Cell Lung Cancer

Advanced Non-Small Cell Lung Cancer
Coherus Biosciences, Inc.
Arcus Biosciences, Inc.; Surface Oncology

Terminated

Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer

United States, Canada
Taiho Oncology, Inc.
Quintiles, Inc.; United BioSource, LLC

Completed

Phase 2 Study of S-1 in Advanced or Metastatic Pancreatic Cancer

Locally Advanced or Metastatic Pancreatic Cancer
NSABP Foundation Inc
Genentech, Inc.; US Oncology Research

Completed

A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer

Breast Cancer

United States, Ireland

Clinical Trials Sponsored by Istari Oncology, Inc.

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