Clinical Trials Sponsored by Johannes Gutenberg University Mainz

Total 229 results

Johannes Gutenberg University Mainz

Unknown

Regional Cerebral Hemodynamics Related to Global Hemodynamics

Critically Ill Patients

Germany
Johannes Gutenberg University Mainz

Completed

Study to Evaluate Anxiety Sensitivity and Somatic Symptoms as Risk Factors for PONV (somPONV)

Postoperative Nausea and Vomiting

Germany
Johannes Gutenberg University Mainz

Completed

Fluid Management Study to Evaluate Changes in Intravascular Volume After Applying Various Pressure Levels on the Caval Vein

Intravascular Volume | Respiratory Changes

Germany
Johannes Gutenberg University Mainz

Completed

Perfusion Index (PI) and Pleth Variability Index (PVI) in Patients With Interscalene Blocks in Orthopedic Surgery (PI-PVI)

Orthopedic Surgery | Perfusion Index and Pleth Variability Index | Interscalene Blocks

Germany
Johannes Gutenberg University Mainz

Completed

Efficacy of Irinotecan and Capecitabine Versus(vs) Cisplatin and Capecitabine in Patients With Esophago-Gastric Cancer

Gastric Cancer

Germany
Johannes Gutenberg University Mainz
Novartis

Completed

Functional and Structural Outcomes in Neovascular Age-related Macular Degeneration (CAPTAIN)

Neovascular Age-related Macular Degeneration

Germany
Median
Johannes Gutenberg University Mainz

Completed

Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery

Lumbar Pain Syndrome

Germany
Johannes Gutenberg University Mainz
AstraZeneca

Completed

Change of Inspiratory Peak Flow in COPD

Chronic Obstructive Pulmonary Disease

Germany
Median
Johannes Gutenberg University Mainz

Recruiting

Passive Microprocessor-controlled Knees vs. Active Microprocessor-controlled Knees After Transfemoral Amputation

Amputation

Germany
Johannes Gutenberg University Mainz
GlaxoSmithKline

Terminated

Effects of Mepolizumab Compared to Placebo on Airway Physiology in Patients With Eosinophilic Asthma: MEMORY Study (MEMORY)

Asthma

Germany
Johannes Gutenberg University Mainz
Pfizer

Completed

Efficacy and Safety of Sunitinib in Metastatic Gastric Cancer

Gastric Adenocarcinoma | Barrett Esophagus

Germany
Johannes Gutenberg University Mainz
Pfizer

Unknown

Varenicline for Alcohol Dependence

Alcohol Dependence

Germany
Johannes Gutenberg University Mainz
Linkoeping University

Completed

Comparison of an Internet-based Guided Self-help and a Group Therapy for Chronic Tinnitus (MINT)

Tinnitus

Germany
Johannes Gutenberg University Mainz
Linkoeping University

Completed

Internet-based Guided Self-help for Chronic Tinnitus (TITUS)

Tinnitus

Sweden
Katrin Lorenz

Completed

COSOPT-S® Treatment Versus Acetazolamide Before Trabeculectomy

Glaucoma

Germany
K. Lieb

Completed

Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players (CHESS)

Cognitively Healthy Subjects Influenced by Psychoactive Drugs

Germany
Tommaso Gori

Recruiting

Treatment of Coronary Bifurcation Lesions: Comparing Reverse T and Protrusion Versus Double-kissing and Crush Stenting (TIPTAP-I)

Coronary Artery Disease

Germany
Tommaso Gori

Completed

EffectivenesS of Additional X-ray PRotection dEviceS in Reducing Scattered Radiation in Radial interventiOn (ESPRESSO)

Exposure of Member of Staff to Medical Diagnostic X-Ray

Germany
University Medical Center Mainz
Johannes Gutenberg University Mainz

Completed

Systemic Lupus Erythematosus Exercise Program (SLEEP)

Systemic Lupus Erythematosus

Germany
Johannes Gutenberg University Mainz
Goethe University

Completed

Role of a Wheat Containing Diet on Non-alcoholic Steatohepatitis (NASH-ATI)

Diabetes Mellitus, Type 2 | Hyperlipidemias | NASH - Nonalcoholic Steatohepatitis

Germany
Johannes Gutenberg University Mainz
Neovasc Inc.

Recruiting

COSIMA: COronary SInus Reducer for the Treatment of Refractory Microvascular Angina (COSIMA)

Refractory Angina | Coronary Microvascular Disease

Germany
Johannes Gutenberg University Mainz
Boehringer Ingelheim

Completed

Effects of Empagliflozin on Left Ventricular Diastolic Function Compared to Usual Care in Type 2 Diabetics (EmDia)

Diabetes Mellitus, Type 2 | Diastolic Dysfunction

Germany
Prof. Huss

Terminated

Adherence to Stimulant Treatment in Attention-Deficit Hyperactivity Disorder (ADHD) Patients (ASTA) (ASTA)

ADHD

Germany
Sensate LLC
Johannes Gutenberg University Mainz

Completed

METHOD (Minimally Invasive, Endoscopically-delivered, Tolerable by Human Individuals, Non-morbid Obesity Device) Study (SENSATE)

Obesity, Non-morbid

Germany
University of Leipzig
Johannes Gutenberg University Mainz

Recruiting

Intensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study (Find-AF2)

Ischemic Stroke | Atrial Fibrillation

Germany
Johannes Gutenberg University Mainz
University of Zurich

Completed

Coronavirus Disease (COvid-)19 REgistry on THROMBOSIS Complications (CORE-THROMB)

Covid19

Ireland, Germany, Italy, Brazil, Denmark, Mexico, Spain, Turkey
Johannes Gutenberg University Mainz
University of Potsdam

Completed

Competence-feedback and Therapy Outcome

Depression

Germany
Johannes Gutenberg University Mainz
University of Cologne

Unknown

An Examination of the Effects of Health-related Internet Use in Individuals With Pathological Health Anxiety Using Ambulatory Assessment

Health Anxiety
Johannes Gutenberg University Mainz
University of Oxford

Unknown

Simulation Efficacy in Neurosurgical Education (SENSE)

Simulation | Intraventricular Hemorrhage | Hydrocephalus | Educational

Germany
Johannes Gutenberg University Mainz
Leap Therapeutics, Inc.

Unknown

DKN-01 Inhibition in Advanced Liver Cancer

Hepatocellular Carcinoma

Germany
Rheinhessen-Fachklinik Alzey
Johannes Gutenberg University Mainz

Unknown

A Validation Study of the German Autobiographical Memory Interview

Retrograde Amnesia

Germany
Johannes Gutenberg University Mainz
Roche Pharma AG

Completed

Peg-interferon ADDed to an Ongoing Nucleos(t)Ide Based Treatment in Patients With Chronic Hepatitis B to Induce Decrease of HBs-Antigen (PADD-ON)

Chronic Hepatitis B

Germany
Dr. Carl Schimanski

Unknown

FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema (DERMATUX)

Colorectal Cancer Metastatic

Germany
Johannes Gutenberg University Mainz
UCB Pharma GmbH

Completed

Study on the Treatment of Elderly Patients With Older and Newer Antiepileptic Drugs (STEP-ONE)

Focal Epilepsy

Germany
Johannes Gutenberg University Mainz
Dentsply Sirona Implants

Unknown

PEERS Multicenter Osseospeed TM TX Profile Implant: German Astra Soft Tissue (GAST) Maintenance Study (GAST)

Inclined Atrophy of the Distal Mandible | Socket Like Atrophy of the Aesthetic Zone

Germany
Kranus Health GmbH
Johannes Gutenberg University Mainz

Not yet recruiting

RCT on Multimodal Self-treatment for Women With Incontinence Using a Digital Health Application (DINKS)

Urinary Incontinence | Urinary Incontinence, Urge | Overactive Bladder Syndrome | Urinary Incontinence,Stress | Female Urinary Stress Incontinence

Germany
Michael Hopp
AstraZeneca

Recruiting

Efficacy and Safety of Standard of Care Plus Durvalumab in Patients With Limited Disease Small Cell Lung Cancer (DOLPHIN)

Small Cell Lung Cancer Limited Stage

Germany
Dr. Serge Thal

Active, not recruiting

Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate (NICA)

Cardiopulmonary Arrest With Successful Resuscitation | Cardiac Arrest | Cerebral Oxygenation

Germany
Johannes Gutenberg University Mainz
Rhön-Klinikum AG

Completed

Enhancing Inpatient Psychotherapeutic Treatment With Online Self-help : Acceptance and Efficacy

Depression

Germany
PENTAX Europe GmbH
Johannes Gutenberg University Mainz

Terminated

Endomicroscopy in Ulcerative Colitis

Ulcerative Colitis

Germany, Italy
University of Zurich
Johannes Gutenberg University Mainz

Withdrawn

Comparison of Surgical Treatment Options for Primary Congenital and Developmental Glaucomas (STOP-Glaucoma)

Primary Congenital Glaucoma | Developmental Glaucoma
Johannes Gutenberg University Mainz
University of Jena

Completed

Nutritional Counseling vs. Nutritional Supplements for NASH - a Randomized Prospective, Open Label Pilot Study (NucesNASH)

Non-alcoholic Fatty Liver Disease | Fatty Liver, Nonalcoholic

Germany
Johannes Gutenberg University Mainz
University of Cologne

Unknown

An Examination of the Effects of Health-related Internet Use in Individuals With Pathological Health Anxiety

Hypochondriasis
Johann Wolfgang Goethe University Hospital
Johannes Gutenberg University Mainz; Kerckhoff Klinik

Recruiting

International T1 Multicenter Outcome Study (T1Outcome-DE)

Coronary Artery Disease | Heart Failure | Chronic Kidney Diseases | Cardiomyopathies | Inflammatory Disease

Germany
Johannes Gutenberg University Mainz
AIO-Studien-gGmbH

Completed

Efficacy of Cetuximab in Combination With Irinotecan and 5- FU/FA in Treatment of Metastatic Gastric Cancer (GC-CIF-2005)

Adenocarcinoma of Stomach or Esophagogastric Junction

Germany
Johannes Gutenberg University Mainz
Leiden University Medical Center

Recruiting

Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life (SERENITY)

Terminal Cancer

Germany, Netherlands, United Kingdom, Spain, Denmark, France, Italy, Poland
Charite University, Berlin, Germany
Johannes Gutenberg University Mainz

Completed

Observational Study of Endothelial Dysfunction in Phenylketonuria

Phenylketonuria | Endothelial Dysfunction
Johannes Gutenberg University Mainz
Engelhard Arzneimittel GmbH & Co.KG

Terminated

Efficacy Study of Polyunsaturated Fatty Acids in Children and Adolescents With Attention Deficit/ Hyperactivity Disorder (PAD)

ADHD

Germany
Shaare Zedek Medical Center
Johannes Gutenberg University Mainz

Completed

Relation Between Polymorphism in Genes Related to Kidney Disease and Renal Manifistations in Fabry Disease

Renal Disease | Fabry
Johannes Gutenberg University Mainz
Merck KGaA, Darmstadt, Germany

Completed

Avelumab Treatment in Patients With Neuroendocrine Carcinomas (NEC G3) Progressive After Chemotherapy (AveNEC)

Cancer

Germany

Clinical Trials Sponsored by Johannes Gutenberg University Mainz

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