Clinical Trials Sponsored by National Institutes of Health Clinical Center (CC)

Total 8096 results

National Cancer Institute (NCI)

Recruiting

The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)

Melanoma

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer

Gastroesophageal Junction (GEJ) Cancers | Advanced HNSCC

United States
National Cancer Institute (NCI)

Recruiting

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

Ovarian Cancer | Gastrointestinal Cancer | Peritoneal Carcinomatosis | Peritoneal Mesothelioma | Appendiceal Cancer

United States
National Cancer Institute (NCI)

Recruiting

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

Olfactory Neuroblastoma | Esthesioneuroblastoma

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Docetaxel in Adults With Metastatic Castration Sensitive and Castration Resistant Prostate Cancer

Cancer Of Prostate | Prostate Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Connect for Cancer Prevention Study (Connect)

Cancer | General Research Use

United States
National Cancer Institute (NCI)

Recruiting

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients

Anxiety

United States
National Cancer Institute (NCI)

Recruiting

Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease

Chronic GVHD

United States
National Cancer Institute (NCI)

Recruiting

Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Urogenital Neoplasms | Bladder Cancer | Urothelial Cancer | Genitourinary Cancer | Urogenital Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumors | Von Hippel-Lindau Disease | VHL Pancreatic Neuroendocrine Tumors

United States
National Cancer Institute (NCI)

Recruiting

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Non-Hodgkin's Lymphoma | NHL | DLBCL

United States
National Cancer Institute (NCI)

Recruiting

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Glioma | High Grade Glioma | Malignant Glioma | Gliomas | Low Grade Glioma

United States
National Cancer Institute (NCI)

Recruiting

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Hepatocellular Carcinoma | Hepatocellular Cancer | Metastatic Hepatocellular Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Immune System Diseases | Lymphoproliferative Disorders | Peripheral T-cell Lymphomas

United States
National Cancer Institute (NCI)

Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

Gastric Cancer | Pancreatic Cancer | Rectal Cancer | Colon Cancer | Gastrointestinal Cancer

United States
National Cancer Institute (NCI)

Recruiting

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

Lymphoma, Non-Hodgkin | Acute Lymphoblastic Leukemia | Acute Lymphocytic Leukemia | Acute Lymphoid Leukemia | B-Cell Leukemia | Leukemia, Lymphocytic, B Cell | B-Cell Lymphoma | B-All | B-NHL | B-Non Hodgkin Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

Prostatic Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Sample Collection and Tracking for the Developmental Therapeutics Clinic

Neoplasms | Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Lymphoma | Diffuse Large B-Cell Lymphoma | Burkitt Lymphoma | Non-Hodgkin Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

Gastric Cancer | Pancreatic Cancer | Rectal Cancer | Colon Cancer | Gastrointestinal Cancer

United States
National Cancer Institute (NCI)

Recruiting

Clonal Evolution in Follicular Lymphoma

Follicular Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Thymic Carcinoma | Thymoma

United States
National Cancer Institute (NCI)

Recruiting

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Stomach Neoplasms | Stomach Cancer | Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS) | Hereditary Diffuse Gastric Cancer (HDGC) | Familial Diffuse Gastric Cancer

United States
National Cancer Institute (NCI)

Recruiting

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Tissue Donors

United States
National Cancer Institute (NCI)

Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Non-Small Cell Lung Cancer | Leukemia-Lymphoma, Adult T-Cell

United States
National Cancer Institute (NCI)

Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome | Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
National Cancer Institute (NCI)

Recruiting

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Neurofibromatosis 1 | Plexiform Neurofibromas

United States
National Cancer Institute (NCI)

Recruiting

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

Solid Tumors

United States
National Cancer Institute (NCI)

Recruiting

Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Leukemia | Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma

Primary Central Nervous System Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

Brain Tumor

United States
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

Adenocarcinoma | Advanced Non-Small Cell Lung Cancer | Squamous Cell Carcinoma | Advanced NSCLC | Adenosquamous Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

Cancer | HIV | Chronic Granulomatous Disease | Dock 8 Deficiency

United States
National Cancer Institute (NCI)

Recruiting

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

Stomach Neoplasms | Pancreatic Neoplasms | Thymoma | Mesothelioma | Biliary Tract Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

Colorectal Neoplasms | Cholangiocarcinoma | Bile Duct Cancer | Pancreas Cancer | Gastric Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

MDS | Immunodeficiency | GATA2

United States
National Cancer Institute (NCI)

Recruiting

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

Prostatic Neoplasms | Prostate Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Children and Adults With Medullary Thyroid Cancer

Medullary Thyroid Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | KSHV | HHV-8

United States
National Cancer Institute (NCI)

Recruiting

Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer

Gastrointestinal Cancer | Cancer of Gastrointestinal Tract | Non-GI Cancers

United States
National Cancer Institute (NCI)

Recruiting

Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes

Genes | Sporadic Chordoma

United States
National Cancer Institute (NCI)

Recruiting

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

Breast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Liver Cancer

United States
National Cancer Institute (NCI)

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Malignant Pleural Mesotheliomas NOS | Esophageal Cancers NOS | Lung Cancer NOS | Thoracic Cancers | Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

Chronic Graft vs. Host Disease

United States
National Cancer Institute (NCI)

Recruiting

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Kidney Cancer | Renal Tumor Histology | Cutaneous Leiomyoma

United States
National Cancer Institute (NCI)

Recruiting

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Kidney Cancer | Kidney Neoplasms | Pneumothorax | FLCN Protein, Human

United States
National Cancer Institute (NCI)

Recruiting

Collection of Blood, Bone Marrow, Tumor, or Tissue Samples From Patients With Cancer to Study Drug Resistance

Renal Cell Carcinoma | Cervical Carcinoma | Lung Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

Pediatric Cancer

United States
National Cancer Institute (NCI)

Completed

Removal of the Ovaries/Fallopian Tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk

Breast Cancer | Ovarian Cancer

United States

Clinical Trials Sponsored by National Institutes of Health Clinical Center (CC)

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CROs in Philippines

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