Clinical Trials Sponsored by Paion UK Ltd.

Total 191 results

Alimentary Health Ltd
Whately-Smith Ltd, King's Langley,UK

Completed

Study in Patients With Mild to Moderate Psoriasis (AH-PSR-01)

Psoriasis

Ireland
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Multiple Myeloma | Chronic Lymphocytic Leukaemia | B-cell Non-Hodgkin's Lymphoma

United Kingdom
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Parkinson's Disease

United Kingdom
Medical Ethics UK Ltd
ProTherax Ltd; Welsh Wound Innovation Centre Ltd

Unknown

Single-centre Study to Investigate Safety and Efficacy of Tri-Solfen in Wound Debridement

Anesthesia, Local | Wounds Injuries

United Kingdom
Imperial College London
Incyte Biosciences UK Ltd

Active, not recruiting

Itacitinib in Advanced Hepatocellular Carcinoma (JAKaL)

Advanced Hepatocellular Carcinoma

United Kingdom
Universitaire Ziekenhuizen KU Leuven
Biocompatibles UK Ltd

Withdrawn

Chemoembolisation With CPT11 Loaded DC Bead With Cetuximab and 5FU/LV in First Line in Patients With KRAS Wildtype mCRC

Colorectal Cancer | Liver Metastases
Biocon Biologics UK Ltd
Biotrial

Completed

Comparison of Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Bmab 1000 and Prolia® in Normal Healthy Volunteers: DENARIUS: DENosumab Pharmacokinetic equivAlence tRIal in Healthy volUnteerS (DENARIUS)

Healthy Volunteers

United States
Generic Devices Consulting, Inc.
Biocompatibles UK Ltd

Terminated

Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal Cancer (PARAGON)

Unresectable Metastatic Colo-rectal Cancer

United States
British Columbia Cancer Agency
Biocompatibles UK Ltd

Completed

Ability of a New Design of Iodine 125 Seed to Maintain Intended Position When Implanted in the Prostate (FAST)

Prostate Cancer

Canada
University of Exeter
Innovate UK; Mitocholine Ltd

Recruiting

The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function (MCh1)

Cognitive Function | Exercise Performance

United Kingdom
CSL Behring
UBC Late Stage (UK) Ltd.

Completed

Assess Burden of Disease Among Kidney Transplant Recipients With Chronic Active Antibody Mediated Rejection

Antibody-mediated Rejection in Kidney Transplant

United States
Daiichi Sankyo, Inc.
Daiichi Sankyo UK Ltd.

Terminated

A Study of DS-2248 in Participants With Advanced Solid Tumors

Non-small Cell Lung Carcinoma | Solid Tumors

United States
Pharmacosmos UK Ltd
BioStata

Completed

Time to Relapse of Iron Deficiency Anaemia After Standard Treatment With The Intravenous Iron (Monofer®)

Iron Deficiency Anaemia

United Kingdom
University of Nottingham
Arthritis Research UK Pain Centre; Nottingham University Hospitals Charity

Completed

Ibuprofen Gel or Capsaicin Cream for my Painful Knee Osteoarthritis?

Osteoarthritis, Knee

United Kingdom
Nutricia UK Ltd
National Health Service, United Kingdom

Completed

High Energy High Protein Peptide Feed Study

Malnutrition | Malabsorption

United Kingdom
MeiraGTx UK II Ltd
Janssen Research & Development, LLC

Completed

Gene Therapy for Achromatopsia (CNGA3) (CNGA3)

Achromatopsia

United Kingdom, United States
Federation Francophone de Cancerologie Digestive
Biocompatibles UK Ltd

Completed

Intra-arterial Hepatic Beads Loaded With Irinotecan With Concomitant Chemotherapy With FOLFOX in Patients With Colorectal Cancer With Unresectable Liver Metastases: a Phase II Multicenter Study

Colorectal Cancer With Non Resectable Hepatic Metastasis

France
Kyowa Hakko Kirin UK, Ltd.

Completed

A Study of KW-3357 in Congenital Antithrombin Deficiency

Congenital Antithrombin Deficiency

France, Germany, Italy, Sweden, United Kingdom
The Christie NHS Foundation Trust
Terumo UK Ltd.

Not yet recruiting

Radial Artery Access (RADIAL)

Radiology, Interventional
MeiraGTx UK II Ltd
Syne Qua Non Limited

Completed

Long-Term Follow-Up Gene Therapy Study for Leber Congenital Amaurosis OPTIRPE65 (Retinal Dystrophy Associated With Defects in RPE65)

Eye Diseases | Retinal Diseases | Eye Diseases, Hereditary | Leber Congenital Amaurosis (LCA)

United States, United Kingdom
Mologic Ltd
University College London Hospitals; Innovate UK

Unknown

The Performance of the Mologic Biomarker Panel in Infection

Sepsis | Infection

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited
Alba Science Ltd

Completed

A 24 Hour Occlusive Single Patch Test to Assess Acute Tolerance of Pre Lubricated Condom on a Panel of Healthy Adult Subjects

Healthy

United Kingdom
Medical University of Graz
Neoss Ltd., Harrogate, UK

Completed

Two Interforaminal Implants in an Immediate or Delayed Loading Protocol for the Elderly

Edentulous Jaw

Austria
M.D. Anderson Cancer Center
Daiichi Sankyo UK Ltd.

Terminated

Ascending Dose and Exploratory Expansion Study of DS-3032b, an Oral MDM2 Inhibitor, in Subjects With Relapsed and/or Refractory Multiple Myeloma

Myeloma

United States
ClinSearch
Biocompatibles UK Ltd; European Georges Pompidou Hospital

Unknown

Prostate Embolization for Acute Urinary Retention Study (PARIS1)

Prostatic Hypertrophy, Benign

France
Kyowa Kirin, Inc.
Kyowa Hakko Kirin UK, Ltd.

Completed

An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018

Parkinson's Disease

United States
dorsaVi Ltd
International Spine, Pain and Performance Center

Suspended

dorsaVi Back Pain and Movement Registry (BPAM)

Low Back Pain

United States
Vaccitech (UK) Limited
Clinical Network Services (CNS) Pty Ltd

Terminated

Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults

Influenza

Australia
B. Braun Medical UK Ltd.

Completed

Acceptability Study on Oral Nutrition Supplement (ONS)

Oral Nutritional Supplementation

United Kingdom
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
Vitaccess Ltd
Royal Marsden NHS Foundation Trust; Melanoma UK

Completed

The Impact of Melanoma and Drug Treatment in the Real World

Melanoma

United Kingdom
Centessa Pharmaceuticals (UK) Limited
LockBody Therapeutics Ltd

Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of LB101 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

United States, France
MeiraGTx UK II Ltd
Syne Qua Non Limited; EMAS Pharma

Completed

Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3

Achromatopsia

United Kingdom, United States
MeiraGTx UK II Ltd
Syne Qua Non Limited; Bionical Emas

Completed

Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)

X-Linked Retinitis Pigmentosa

United Kingdom, United States
Oviva UK Ltd
Guy's and St Thomas' NHS Foundation Trust

Active, not recruiting

The Transform Type 2 Diabetes Study (Transform)

Type2diabetes

United Kingdom
UCB Biopharma S.P.R.L.
Pharm Research Associates (UK) Ltd.

Completed

Study to Look at How Effective Briviact is as add-on Treatment for Patients With Epilepsy With Partial Onset Seizures (BASE)

Epilepsy With POS With or Without Secondary Generalization

Denmark, Germany, Hungary, Ireland, Italy, Netherlands, Norway, Spain, United Kingdom
MeiraGTx UK II Ltd
Syne Qua Non Limited; EMAS Pharma

Completed

Gene Therapy for Achromatopsia (CNGB3) (CNGB3)

Achromatopsia

United Kingdom, United States
Guy's and St Thomas' NHS Foundation Trust
Volition Diagnostics UK Ltd

Recruiting

ObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients With Sepsis to Facilitate Early Diagnosis and Prognostication. (EPICETUS) (EPICETUS)

Sepsis

United Kingdom
Queen Mary University of London
Innovate UK; Closed Loop Medicine Ltd

Completed

Personalised Electronic Record Supported Optimisation When Alone for Patients With Hypertension (PERSONALCovdBP)

Hypertension

United Kingdom
Owlstone Ltd
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK

Completed

PAN-study: Pan-Cancer Early Detection Study (PAN)

Gastric Cancer | Esophageal Cancer | Liver Cancer

United Kingdom
Imperial College London
Biocompatibles UK Ltd, a BT International group company

Recruiting

TheraSphere Selective Internal Radiation Therapy (SIRT) as Treatment for Neuroendocrine Tumours With Liver Mets (ArTisaN)

Neuroendocrine Tumors | Liver Metastases

United Kingdom
Worthington-Kirsch, Robert L., M.D.
Terumo Medical Corporation; Biocompatibles UK Ltd

Completed

Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlock™ Embolic Agent

Uterine Neoplasms | Leiomyoma | Leiomyomatosis

United States
King's College Hospital NHS Trust
Ampersand Health Ltd; Neuroendocrine Cancer UK

Recruiting

Mobile Application to Collect PRO Data in NET Patients

Neuroendocrine Neoplasms (Tumours)

United Kingdom
Daiichi Sankyo UK Ltd, a Daiichi Sankyo Company

Completed

Study to Evaluate the Use of Direct Oral Anticoagulants in UK Clinical Practice For Patients With a First Stroke Attributable to Nonvalvular Atrial Fibrillation

Atrial Fibrillation

United Kingdom
University of Nottingham
Mediplus Ltd UK; Enteric healthcare technology Co-operative

Completed

Evaluation of 'Melody' Paracentesis Device for Ascites Therapy (EMPATHY)

Ascites Hepatic | Cirrhosis and Chronic Liver Disease

United Kingdom
King's College London
University of Oxford; QinetiQ Ltd; UK Space Agency

Completed

Advanced Gravitational Physiology the Lung Under High-G Acceleration

Respiratory Physiology

United Kingdom
Oxford University Hospitals NHS Trust
The Dystonia Society of the United Kingdom; Globsource UK; Statsconsultancy Ltd...

Completed

A Mechanical Device for Blepharospasm

Blepharospasm
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 2 Project (StOIC-2)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
Oviva UK Ltd
University College, London; Hull University Teaching Hospitals NHS Trust

Recruiting

SAFE-LCD Trial, for Insulin-treated Adults Living With Type 2 Diabetes

Type 2 Diabetes Treated With Insulin | Diet Habit

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Nutricia UK Ltd

Completed

Investigating the Energy Expenditure of Acute Spinal Cord Injured Patients

Spinal Cord Injury, Acute

United Kingdom

Clinical Trials Sponsored by Paion UK Ltd.

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