Clinical Trials Sponsored by Scripps Translational Science Institute

Total 349 results

Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Completed

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage I Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
University of Florida
University of Florida Clinical and Translational Science Institute (CTSI)

Completed

Blood Flow Restriction Exercise Study (BFR)

Osteoarthritis, Knee

United States
West Virginia University
NovoCure Ltd.; West Virginia Clinical and Translational Science Institute

Withdrawn

Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells

Glioblastoma | Glioblastoma Multiforme

United States
University of Colorado, Denver
National Cancer Institute (NCI); Colorado Clinical & Translational Sciences...

Terminated

Combined Modality Exercise and Appetite in Breast Cancer Survivors (CARE)

Overweight and Obesity | Breast Cancer Female

United States
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Recruiting

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Recurrent Colorectal Carcinoma | Locally Advanced Colorectal Carcinoma | Stage III Colorectal Cancer

United States
Washington University School of Medicine
Institute of Clinical and Translational Sciences

Withdrawn

In-Home Sensor Monitoring of Older Adults With Cancer

Cancer
University of Washington
University of Washington Institute for Translational Health Science (KL2)

Completed

Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease

Diabetes Mellitus | Diabetic Kidney Disease | Chronic Kidney Disease

United States
University of California, San Diego
Duke University; University of California, San Francisco; Harvard University; Mount... and other collaborators

Completed

Self-Directed Biological Transformation Initiative (SBTI)

Healthy

United States
Oregon Health and Science University
National Institutes of Health (NIH); Oregon Clinical and Translational Research...

Completed

Oral Contraceptive Efficacy and Body Weight

Body Weight | Contraception

United States
UNC Lineberger Comprehensive Cancer Center
North Carolina Translational and Clinical Sciences Institute

Completed

Feasibility of an 8-week Tai Chi Chuan Intervention for Breast Cancer Survivors

Cognitive Impairment | Cancer, Breast

United States
University of Colorado, Denver
Cystic Fibrosis Foundation; Colorado Clinical & Translational Sciences Institute

Completed

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

Cystic Fibrosis

United States
University of Washington
University of Washington Institute for Translational Health Science (UL1...

Completed

Thermotape High-adhesion Medical Tape Comparison Study

Skin Injury

United States
Todd Schroeder
Southern California Clinical and Translational Science Institute

Completed

Resistance Training and Neuroimaging (RTNI)

Cognitive Decline | Cerebrovascular Function

United States
Medical College of Wisconsin
Mallinckrodt; Versiti; Clinical & Translational Science Institute of Southeast...

Completed

Nitric Oxide Administration During Pediatric Cardiopulmonary Bypass Surgery to Prevent Platelet Activation

Inflammation | Platelet Dysfunction

United States
Michael Kyle Ritchie
West Virginia Clinical and Translational Science Institute

Completed

Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)

Cardiac Arrest | Circulatory Failure

United States
Indiana University
National Institutes of Health (NIH); National Center for Advancing Translational... and other collaborators

Enrolling by invitation

Adapting an Adolescent Friendly PrEP Program for Uasin Gishu County-Kenya

Stigma, Social | HIV Pre-exposure Prophylaxis

Kenya
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Active, not recruiting

MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus (MERMAID-T1D)

Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Diabetes Mellitus Complication | Metabolic Disease | Type1 Diabetes Mellitus | Autoimmune Diabetes | Juvenile Diabetes

United States
Indiana University
Indiana Clinical and Translational Sciences Institute; Purdue University; Moi...

Completed

Diagnosis of Gestational Diabetes in Eldoret, Kenya

Diabetes, Gestational
University of Maryland, Baltimore
National Center for Advancing Translational Sciences (NCATS); University of...

Completed

Adjunct VR Pain Management in Acute Brain Injury

Trauma | Traumatic Brain Injury | Pain, Acute | Headaches Posttraumatic

United States
University of Iowa
Osseointegration Foundation; University of Iowa Institute of Clinical and Translational...

Completed

The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study

Obesity | Peri-implant Inflammation | Peri-implantitis

United States
Oregon Health and Science University
Oregon Clinical and Translational Research Institute; Pulsion Medical Systems

Completed

Hemodynamics and Extravascular Lung Water in Acute Lung Injury (HEAL)

Acute Lung Injury

United States
Susan J. Hayflick
Oregon Health and Science University; Oregon Clinical and Translational Research...

Completed

Brain Perfusion in Pantothenate Kinase-associated Neurodegeneration (PKAN)

Pantothenate Kinase-associated Neurodegeneration (PKAN)

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Recruiting

The Validation Study of Bioelectronics

Healthy | Health Behavior

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Pilot Study on Training Emerging Adults Skills in Navigating College (SINC)

Alcohol Abuse | Cognitive Deficit in Attention

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Love Infection: A Dramatized Story Intervention (Telenovela/Soap Opera) for HIV Prevention (IA)

HIV Infections

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

COVID-19 Household Transmission Study (CO-HOST)

COVID-19

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Impact of Sugar-Sweetened Beverage Health Warnings

Dietary Habits

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

4-week Mindfulness Program for Adults With Chronic Pain

Chronic Pain

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Active and Passive Music Therapy Interventions

Autonomic Nervous System Imbalance | Hypothalamic Pituitary Adrenal Axis Suppression

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Multidrug Resistant Gram-negative Bacilli Colonization and Infection in Burn

Multi-drug Resistant Gram-negative Bacilli Colonization

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Determining Relationships Among Maternity Stress & Sleep (DREAMSS)

Depression | Postpartum Depression

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Recruiting

Detection of Brown Adipose Tissue by Magnetic Resonance Imaging (BAT_PET/MRI)

Obesity

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Evaluation of an Interdisciplinary Decision Guide for Infant Feeding Assessment

Premature Birth | Feeding and Eating Disorders of Childhood

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Wrist Fracture Evaluation With a Desktop Orthopedic Tomosynthesis System

Fracture

United States
Washington University School of Medicine
Washington University Institute of Clinical and Translational Sciences

Completed

Determining Effectiveness of an mHealth Intervention to Provide Adolescent CBT

Anxiety Disorders | Adolescent Depression

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls (EVOLVE)

Stress | Emotional Disturbances | Adolescent Development

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

A Study of the Feasibility of Prehospital Remote Ischemic Conditioning

Chest Pain

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder

Autism Spectrum Disorder | Autistic Disorder | Neurodevelopmental Disorder | Childhood Developmental Disorders, Pervasive

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Pharmacokinetics of Apixaban in Nephrotic Syndrome

Proteinuria | Nephrotic Syndrome

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Tracking Outcomes in Pain Patients Using Fitness Devices

Back Pain | Chronic Pain

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

An Open Label Trial of Bupropion and Naltrexone for Binge Drinking

Binge Drinking

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Phase I Study of Nicotinamide for Early Onset Preeclampsia

Hypertension | Pregnancy Induced Hypertension | Superimposed Preeclampsia

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Walk With Ease Program For Patients With Systemic Lupus Erythematosus (Walk SLE)

Systemic Lupus Erythematosus

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Terminated

Feasibility of Heart Rate Variability Biofeedback With In-patient Pregnant Women

Maternal Health Services | Maternal Anxiety | Maternal Stress

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Improving Diabetes Outcomes for Persons With Severe Mental Illness

Diabetes

United States
Franziska Wachter
Harvard Clinical and Translational Science Center (Harvard Catalyst)

Recruiting

A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies (MORE)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | MDS | Aml | Myeloid Neoplasm | Myeloid Malignancies | Inherited Bone Marrow Failure Syndrome

United States
University of Florida
American Psychological Foundation; Clinical & Translational Science Institute; American Psychological Association (APA)

Completed

The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury

Brain Concussion

United States
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill; National Center for Advancing Translational... and other collaborators

Recruiting

Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study

Lynch Syndrome

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

Safety, Tolerability, and Biosignature of Humanized Prebiotics in Healthy Adults

Intestinal Health

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Recruiting

Precision Medicine and Physical Function (HMB)

Frailty | Multiple Chronic Conditions | Weakness, Muscle

United States

Clinical Trials Sponsored by Scripps Translational Science Institute

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