Search clinical trials for: Anti-Retroviral Agents

Total 188622 results

ViiV Healthcare

Recruiting

A Study Evaluating Implementation Strategies for the Delivery of APRETUDE for Black cis-and Transgender Women in United States EHE Territories (EBONI)

HIV Infections

United States
Peking University

Recruiting

Plerixafor for Poorly Mobilized Lymphoma

Lymphoma

China
Fore Biotherapeutics

Recruiting

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Cancer Harboring BRAF Alterations

United States, Germany, Spain, United Kingdom, France, Korea, Republic of, Italy, Sweden, Canada
German Cancer Research Center
University Hospital Heidelberg

Recruiting

A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients With Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma (IntenSify)

Pancreatic Cancer | Pancreatic Adenocarcinoma | CYP3A Inhibitor | Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic Neoplasm

Germany
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity

Acquired Immunodeficiency Syndrome
Emory University
National Cancer Institute (NCI)

Recruiting

Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8

United States
Christian Hinrichs
National Cancer Institute (NCI); Cancer Immunology and Metabolism Center of...

Recruiting

KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer

Cervical Cancer | Breast Cancer | Gastric Cancer | Lung Cancer

United States
Centre Hospitalier St Anne
For Drug Consulting

Recruiting

Therapeutic Evaluation of Low-dose IL-2-based Immunomodulatory Approach in Patients With Early AD (IL-2-AD)

Alzheimer Disease

France
National Taiwan University Hospital
PharmaEssentia

Not yet recruiting

A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection

Hepatitis D

Taiwan
East Carolina University
Janssen Scientific Affairs, LLC

Recruiting

Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain

HIV Infections | Obesity

United States
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study of QLS1128 and in Combination With Ritonavir in Healthy Participants

COVID-19

China
ViiV Healthcare

Recruiting

A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants

HIV Infections

United States
Taichung Veterans General Hospital
Institute of Adherence to Medication

Recruiting

Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection

Safety Issues

Taiwan
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

HIV

United States, Brazil, Puerto Rico, South Africa, Thailand
University of Pennsylvania

Recruiting

Utilization of Hepatitis B Virus NAT+ Donors for Hepatitis B Vaccinated Lung Transplant Candidates (INHIBITOR)

Hepatitis B | Lung Transplant

United States
ANRS, Emerging Infectious Diseases

Not yet recruiting

Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant Women (TOPCHIB)

Hepatitis B Virus - Chronic Active
Theratechnologies
ICON Clinical Research; Excelsus Statistics Inc.; Health Psychology Research...

Recruiting

A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab (PROMISE-US)

HIV Infections | Multi-Antiviral Resistance

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19

COVID-19

United States
Sun Yat-sen University

Recruiting

Antiviral Therapy for Patients With Chronic Hepatitis B Infection

Chronic Hepatitis B Virus Infection

China
Brigham and Women's Hospital
Gilead Sciences; The Fenway Institute

Recruiting

SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder (SmartSteps)

HIV Infections | Substance Use | Adherence, Medication | Adherence, Treatment

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Evaluation of SSD8432 and Ritonavir in Adult Subjects With COVID-19 Clinical Study

COVID-19
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

To Evaluate SSD8432/Ritonavir in Adults With COVID-19

COVID-19
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Sickle Cell Anemia | Beta Thalassemia

United States
University of California, San Francisco
University of Miami

Recruiting

PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men (PrEP2-BAY)

Risk Reduction

United States
Hugh Taylor

Recruiting

Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium

Asherman Syndrome | Recurrent Implantation Failure | Atrophic Endometrium

United States
Liu Tian

Recruiting

Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study of SSD8432 in Healthy Adult Subjects

Healthy Participants

China
University of Wisconsin, Madison
Wisconsin Partnership Program

Recruiting

Lopinavir/Ritonavir in PLWH With High-Grade AIN

High-Grade Anal Intraepithelial Neoplasia

United States
Peking Union Medical College Hospital

Not yet recruiting

A Real-world Study of Lamivudine and Dotiravir Sodium Tablets in the Treatment-naïve HIV-1 Infected Patients

HIV-1-infection
Ascletis Pharmaceuticals Co., Ltd.

Recruiting

Study to Evaluate Safety, Tolerance and Efficacy of ASC22 Combined With ART in Subjects With HIV

HIV Infections | HIV-1-infection | PD-L1 Gene Mutation

China
ImCheck Therapeutics
ILife Consulting; Exystat

Recruiting

Phase 1/2a Study of ICT01 Plus Low Dose SC IL-2 in Patients With Advanced Solid Tumors (EVICTION-2)

Solid Tumor, Adult

France
Hadassah Medical Organization

Recruiting

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Sarcoma, Synovial | Ovary Cancer | Sarcoma,Soft Tissue | Melanoma Stage IV | Bladder Urothelial Carcinoma | Neuroblastoma, Metastatic

Israel
Aulos Bioscience, Inc.

Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Solid Tumor

Australia, United States
Peking University People's Hospital

Recruiting

Efficacy and Immunological Evaluation of Belimumab Plus Low Dose IL-2 in the Treatment of Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

China
Pfizer

Recruiting

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

COVID-19

United States, United Kingdom, Mexico, South Africa, Japan, Bulgaria, Hungary, Puerto Rico
Shanghai HEP Pharmaceutical Co., Ltd.
Shanghai Tong Ren Hospital; Shanghai East Hospital

Recruiting

A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients

Chronic Hepatitis B

China
Orlando Immunology Center
ViiV Healthcare

Recruiting

Changes in Immunologic Parameters Following the Addition of Fostemsavir in Virologically Suppressed Immunologic Non-responders Living With HIV-the RECOVER Study

HIV-1-infection

United States
Institute of Liver and Biliary Sciences, India

Recruiting

TAF (Tenofovir Alafenamide) for Preventing Progression of Liver Disease in Non-cirrhotic Chronic HBV Infection With Normal ALT and Low Viral Load.

Non-cirrhotic, Chronic Hepatitis B

India
Macquarie University, Australia
King's College London; Stichting TRICALS Foundation

Recruiting

Triumeq in Amyotrophic Lateral Sclerosis (LIGHTHOUSE II)

Amyotrophic Lateral Sclerosis

Spain, Australia, United Kingdom, New Zealand, Netherlands, Ireland, Slovenia, Sweden
Nanfang Hospital of Southern Medical University
Gilead Sciences; Tigermed Consulting Co., Ltd

Recruiting

Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF)

Hepatitis B, Chronic | Mother to Child Transmission

China
The Affiliated Hospital of Qingdao University

Recruiting

Bioequivalence of Dotilavir Sodium Tablets in Healthy Subjects in the Fasting and Fed State

Healthy Volunteers

China
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Advanced Locoregional Melanoma | Clear Cell Histology

United States
DualityBio Inc.

Recruiting

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

HER2-positive Advanced Solid Tumor

China, United States, Australia, Puerto Rico
Vall d'Hebron Institute of Oncology
Banc de Sang i Teixits

Recruiting

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors (NEXTGENTIL-ACT)

Epithelial Tumors, Malignant | Malignant Solid Tumor

Spain
Florida International University
National Institute of Mental Health (NIMH)

Recruiting

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT) (TRIDENT)

Depression | Inflammation | HIV-1-infection

United States
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) (DOLPHIN KIDS)

HIV | Tuberculosis

South Africa
Merck Sharp & Dohme LLC

Not yet recruiting

Radiopaque Matrix MK-8591 Implant in Participants at Low-Risk for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591-043)

HIV | Human Immunodeficiency Virus
Stanford University
Orca Biosystems, Inc.

Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | Chronic Myelogenous Leukemia | Allogeneic Hematopoietic Cell Transplantation (HCT) | Advanced Hematologic Malignancies

United States
Radboud University Medical Center

Recruiting

Pharmacokinetic Boosting of Olaparib to Improve Exposure, Tolerance and Cost-effectiveness (PROACTIVE)

Cancer

Netherlands
University of Alabama at Birmingham
National Institute of Allergy and Infectious Diseases (NIAID); Indiana University and other collaborators

Recruiting

Kuwa Free! - Live Free!

HIV Infections | Contraception | Drug-drug Interaction

Kenya

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