Search clinical trials for: BRAF Inhibitor
Total 68211 results
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M.D. Anderson Cancer CenterGenentech, Inc.Active, not recruiting
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National Cancer Institute (NCI)Active, not recruitingGlioblastoma | Malignant Glioma | Anaplastic AstrocytomaUnited States, Canada, Puerto Rico, Australia, New Zealand
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMetastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Refractory Melanoma | BRAF V600 Wild Type | Intracranial MelanomaUnited States
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PfizerMerck Sharp & Dohme LLCActive, not recruitingMelanomaFrance, United States, Hungary, Italy, Spain, Czechia, Belgium, Germany, New Zealand, Canada, Austria, Israel, Poland, Russian Federation, Turkey, Switzerland, South Africa, Slovakia, United Kingdom, Ukraine, Brazil, Argentina, Bulg... and more
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Novartis PharmaceuticalsTerminatedMelanoma | Non-Small Cell Lung CancerItaly, Australia, Belgium, Germany, Spain, Korea, Republic of, Israel, France, United States, Sweden, Poland
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National Cancer Institute (NCI)Active, not recruitingSoft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Malignant Glioma | Ependymoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Rhabdomyosarcoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Refractory Non-Hodgkin Lymphoma and other conditionsUnited States, Puerto Rico
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National Cancer Institute (NCI)Active, not recruitingMalignant Solid Neoplasm | Metastatic Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8United States
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UNC Lineberger Comprehensive Cancer CenterBristol-Myers Squibb; AmgenActive, not recruitingColon CancerUnited States
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PfizerCompleted
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National Cancer Institute (NCI)Active, not recruitingHematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple MyelomaUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingPoorly Differentiated Thyroid Gland Carcinoma | Thyroid Gland Anaplastic Carcinoma | Unresectable Thyroid Gland Carcinoma | Metastatic Thyroid Gland Carcinoma | Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8 | Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8 | Stage IVA Thyroid Gland...United States
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PfizerActive, not recruitingMelanomaCanada, United States, Spain, Germany, Korea, Republic of, Australia, Czechia, Netherlands, France, Hungary, United Kingdom, Switzerland, Singapore, Russian Federation, Italy, Japan, Israel, Brazil, Portugal, Mexico, Greece, Argen... and more
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National Cancer Institute (NCI)Active, not recruitingUnresectable Thyroid Gland Carcinoma | Metastatic Thyroid Gland CarcinomaUnited States
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PfizerActive, not recruitingNon-small Cell Lung CancerUnited States, Spain, Netherlands, Korea, Republic of, Italy
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Hoffmann-La RocheCompletedMetastatic MelanomaFrance, Italy, Spain, Brazil, Latvia, Germany, Hungary, Switzerland
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Taizhou Mabtech Pharmaceutical Co.,LtdActive, not recruitingMetastatic Colorectal CancerChina
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PfizerActive, not recruitingCarcinoma, Non-Small-Cell LungUnited States, Belgium, Taiwan, Australia, United Kingdom
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Saint Petersburg State University, RussiaWithdrawnThyroid Gland Anaplastic CarcinomaRussian Federation
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Hoffmann-La RocheActive, not recruitingMelanomaUnited States, Korea, Republic of, United Kingdom, Australia, France, Belgium, Italy, Portugal, Spain, Brazil, Canada, Russian Federation, Germany, New Zealand, Israel, Poland, Greece, Austria, Hungary, Netherlands
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Genentech, Inc.Active, not recruitingStage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | BRAF NP_004324.2:p.V600X | KRAS wt AlleleUnited States
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University of Southern CaliforniaNational Cancer Institute (NCI)Active, not recruitingStage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | Metastatic Head and Neck... and other conditionsUnited States
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Daiichi SankyoAstraZenecaActive, not recruitingAdvanced Colorectal CancerKorea, Republic of, United States, Taiwan, Belgium, Spain, Japan, United Kingdom, France, Italy, Australia
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingStage IV Bladder Cancer AJCC v8 | Stage IVA Bladder Cancer AJCC v8 | Stage IVB Bladder Cancer AJCC v8 | Bladder Urothelial CarcinomaUnited States
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Erasca, Inc.Active, not recruitingMetastatic Colorectal Cancer | Metastatic Pancreatic Ductal AdenocarcinomaUnited States
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OHSU Knight Cancer InstituteOregon Health and Science UniversityTerminatedPrimary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditionsUnited States
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M.D. Anderson Cancer CenterCompletedPathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8United States
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Memorial Sloan Kettering Cancer CenterCompletedThyroid Cancer, Papillary | Thyroid Cancer, Follicular | Thyroid Carcinoma | Thyroid Cancer | Thyroid Cancer (Follicular Cell) | BRAF V600E Mutation PositiveUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingStage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7United States
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Memorial Sloan Kettering Cancer CenterMassachusetts General Hospital; Weill Medical College of Cornell UniversityActive, not recruiting
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Novartis PharmaceuticalsAvailable
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Novartis PharmaceuticalsAvailable
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditionsUnited States
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University of VirginiaActive, not recruitingReal-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies (Lung001)Lung Cancer | ALK Gene Mutation | MET Gene Mutation | KRAS Mutation-Related Tumors | RET Gene Mutation | EGFR Gene Mutation | EGFR | ROS1 Gene Mutation | BRAFUnited States
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JS InnoPharm, LLCSuspended
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Memorial Sloan Kettering Cancer CenterYale University; Dana-Farber Cancer InstituteActive, not recruitingLeukemia | Leukemia, Hairy Cell | Hairy Cell LeukemiaUnited States
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Novartis PharmaceuticalsActive, not recruitingEGFR-mutant Non-small Cell Lung CancerTaiwan, Germany, Canada, Italy, Singapore, Hong Kong
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Fondazione Melanoma OnlusClinical Research Technology S.r.l.Active, not recruiting
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Day One Biopharmaceuticals, Inc.Available
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Anita TurkEli Lilly and CompanyTerminatedCancer | Cancer Metastatic | BRAF V600E | MEK1 Gene Mutation | MEK2 Gene Mutation | ERK Mutation | RAF1 Gene MutationUnited States
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Stanford UniversityNovartis PharmaceuticalsCompletedAmeloblastoma | BRAF Gene MutationUnited States
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H. Lee Moffitt Cancer Center and Research InstituteGenentech, Inc.; ExelixisActive, not recruitingMelanoma | Skin CancerUnited States
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OHSU Knight Cancer InstituteGenentech, Inc.; Oregon Health and Science UniversityWithdrawnAnatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent... and other conditionsUnited States
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University of California, San FranciscoGenentech, Inc.Active, not recruitingPediatric Recurrent/Refractory BRAFV600E-mutant GliomasUnited States, Canada
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PfizerMerck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. Ltd; Pierre Fabre MedicamentCompletedBRAF V600E-mutant Metastatic Colorectal CancerUnited States, Spain, Korea, Republic of, United Kingdom, Australia, Czechia, Taiwan, Belgium, France, Hungary, Canada, Japan, Russian Federation, Netherlands, Israel, Germany, Turkey, Austria, Brazil, Poland, Italy, Argentina, Chile, Denmar... and more
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Novartis PharmaceuticalsCompletedGlioblastoma | Astrocytoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Pleomorphic Xanthoastrocytoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Gangliocytoma | Central Neurocytoma | Oligodendroglioma, Childhood and other conditionsUnited States, Italy, Japan, Germany, Spain, France, Canada, Australia, Brazil, Israel, Russian Federation, Argentina, United Kingdom, Finland, Belgium, Denmark, Czechia, Sweden, Switzerland, Netherlands
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Craig L Slingluff, JrNational Cancer Institute (NCI)Terminated
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University College, LondonHoffmann-La RocheActive, not recruitingNon-small Cell Lung CancerUnited Kingdom
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Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Active, not recruiting
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St. Justine's HospitalCHU de Quebec-Universite Laval; Montreal Children's Hospital of the MUHCActive, not recruitingLow-grade Glioma | Plexiform Neurofibroma | Central Nervous System GliomaCanada
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University of LouisvilleJames Graham Brown Cancer CenterWithdrawn