Search clinical trials for: Calcineurine inhibitor

Total 68041 results

Beijing Mabworks Biotech Co., Ltd.

Recruiting

A Clinical Study of MIL62 in Primary Membranous Nephropathy

Primary Membranous Nephropathy

China
University Hospital, Tours

Not yet recruiting

Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies (INSTEAD)

Renal Transplant Rejection | Induction Therapy
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

Acute Myeloid Leukemia | Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Secondary Myelofibrosis

United States
HK inno.N Corporation

Not yet recruiting

A Study to Evaluate Effect of IN-A001 on Pharmacokinetics of Tacrolimus in Healthy Volunteers

Healthy

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Recruiting

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus (DIVERT)

Systemic Lupus Erythematosus

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma

Neuroblastoma

China
Aurinia Pharmaceuticals Inc.
Labcorp Drug Development Inc

Recruiting

Voclosporin in Adolescents With Lupus Nephritis (VOCAL)

Adolescent Lupus Nephritis

United States
Johns Hopkins University

Recruiting

Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis (INTRO)

Post-ERCP Acute Pancreatitis

United States, Singapore, India
Taejoon Pharmaceutical Co., Ltd.

Recruiting

Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients

Dry Eye Syndrome

Korea, Republic of
University of Alberta

Recruiting

Extended-Release Tacrolimus Following Liver Transplantation

Cardiovascular Diseases | Renal Insufficiency | Metabolic Syndrome | Liver Transplant; Complications | Immunosuppressant Adverse Reaction

Canada
Leiden University Medical Center

Recruiting

Tacrolimus Versus Mycophenolate for Autoimmune Hepatitis Patients With Incomplete Response on First Line Therapy (TAILOR)

Autoimmune Hepatitis

Netherlands
Sanofi

Recruiting

BIVV020 (SAR445088) n Prevention and Treatment of Antibody-mediated Rejection (AMR)

Transplant Rejection

Germany, Italy, Spain, United States, Canada, France, Sweden
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Recruiting

Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes (DF-IL2-REP)

Type 1 Diabetes

France
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; Shenzhen People... and other collaborators

Recruiting

Sitagliptin for Prevention of aGVHD After Alternative Donor Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation | Acute-graft-versus-host Disease

China
Université de Sherbrooke
McMaster University

Recruiting

Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY) (CINERGY)

Ischemic Reperfusion Injury | Brain Death | Organ Transplant Failure or Rejection

Canada
Zhongshan Ophthalmic Center, Sun Yat-sen University

Recruiting

Microvascular and Inflammatory Responses of 0.05 Cyclosporine Eye Drop (II) in Treatment of Dry Eye

Dry Eye

China
Sun Yat-sen University

Recruiting

Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH

Vogt Koyanagi Harada Disease (VKH)

China
M.D. Anderson Cancer Center

Recruiting

Off-the-shelf NK Cells + SCT for Myeloid Malignancies

Acute Myeloid Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Myeloid Malignancies

United States
Postgraduate Institute of Medical Education and...
All India Institute of Medical Sciences, New Delhi

Not yet recruiting

Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative Colitis (TOCASU)

Ulcerative Colitis
University of British Columbia
Paladin Labs Inc.

Recruiting

Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations (LCP-TAC)

Liver Transplantation | Neurotoxicity | Tremor | Tacrolimus | Immunosuppression

Canada
Stanford University
Orca Biosystems, Inc.

Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | Chronic Myelogenous Leukemia | Allogeneic Hematopoietic Cell Transplantation (HCT) | Advanced Hematologic Malignancies

United States
Assiut University

Recruiting

Second-line Treatment of Primary Autoimmune Hemolytic Anemia

Primary Autoimmune Hemolytic Anemia

Egypt
Thomas Jefferson University

Recruiting

Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma and other conditions

United States
Heleen Grootjans
Chiesi Farmaceutici S.p.A.

Recruiting

Trial Comparing Immediate Versus Extended Release Tacrolimus; Reducing Calcineurin Inhibitor Related Toxicity in Lung Transplantation Patients (REVOLUTION)

Lung Transplant; Complications

Netherlands
ExCellThera inc.
Memorial Sloan Kettering Cancer Center

Recruiting

US Study of ECT-001-CB in Pediatric and Young Adult Patients With High-Risk Myeloid Malignancies

Cord Blood Transplant | High Risk Myeloid Malignancies

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Congenital Amegakaryocytic Thrombocytopenia | Paroxysmal Nocturnal Hemoglobinuria | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome | Bone Marrow Failure Syndrome | Hereditary Sideroblastic Anemia | Hematologic Neoplasm With Germline GATA2 Mutation | Hematologic Neoplasm With Germline SAMD9... and other conditions

United States
The First Affiliated Hospital of Soochow University

Not yet recruiting

Outcomes of Patients After Allo-HSCT With Decitabine and NAC

GVHD | Relapse | Engraft Failure
Fundación Canaria de Investigación Sanitaria

Recruiting

Treatment of Early Borderline Lesions in Low Immunological Risk Kidney Transplant Patients (TRAINING)

Kidney Transplant Failure and Rejection

Spain
Loyola University
Veloxis Pharmaceuticals

Recruiting

Renal Tubular Injury and Transplant Outcomes in Cardiac Recipients Converting From IR Tacrolimus to XR Tacrolimus

Chronic Kidney Diseases | Heart Transplant

United States
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)

Lymphoma | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Mixed Phenotype Acute Leukemia

United States
National Medical Research Center for Children's...

Not yet recruiting

Evaluation of the Effectiveness and Safety of Immunosuppressive and Biological Therapy of Atopic Dermatitis in Childhood

Atopic Dermatitis

Russian Federation
University of Birmingham
IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)

Recruiting

Methods of T Cell Depletion Trial (MoTD) (MoTD)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma | Chronic Myelogenous Leukemia

United Kingdom
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

NMF-CsA-Dupi Trial

Dermatitis, Atopic

Netherlands
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Renal Allograft Recipients

France, Germany, Spain, United Kingdom, Italy, Netherlands, Belgium, United States
Zhejiang University

Recruiting

Ruxolitinib With Calcineurin and Methotrexate vs. Calcineurin Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation

Graft Versus Host Disease

China
Vanderbilt University Medical Center
Veloxis Pharmaceuticals

Recruiting

Cognitive Outcomes in Stable Renal Transplant Patients Switched fromTacrolimus to Envarsus XR™ (OPERATOR)

Renal Transplant

United States
Tel-Aviv Sourasky Medical Center
Weizmann Institute of Science

Recruiting

Cyclosporine in Combination With Carfilzomib and Dexamethasone in Relapsed Multiple Myeloma Refractory to Carfilzomib and High Expression of PPIA Gene in Myeloma Cells

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

Israel
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Cyclosporine on Day Zero as Prophylaxis for Cytokine Release Syndrome

Cytokine Release Syndrome | Stem Cell Transplant Complications

Mexico
Yonsei University

Recruiting

A Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING)

Moderate to Severe Dry Eye

Korea, Republic of
University of Southern California
Veloxis Pharmaceuticals

Recruiting

Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR (SIMPLE)

Kidney Transplantation | Kidney Transplant Rejection

United States
Da, Yuwei, M.D.

Recruiting

Tacrolimus Combined With Low-dose Prednisone for Treatment of Myasthenia Gravis

Myasthenia Gravis

China
Peking University People's Hospital
Beijing Friendship Hospital; Beijing Hospital; The First Affiliated Hospital... and other collaborators

Recruiting

The Combination of Tacrolimus and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia

Immune Thrombocytopenia | ITP

China
Peking Union Medical College Hospital
Beijing Tongren Hospital; Shanghai Fosun Pharmaceutical Industrial Development... and other collaborators

Recruiting

Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN

Idiopathic Membranous Nephropathy

China
Beth Israel Deaconess Medical Center
Veloxis Pharmaceuticals

Not yet recruiting

Efficacy of Envarsus XR and Digital Health Technology in Reducing Tacrolimus Fluctuation and Frequency of Dose Changes

Medication Adherence | Renal Transplant
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Xinqiao Hospital...

Recruiting

MSC for Treatment of cGVHD After Allo-HSCT

Chronic Graft-versus-host Disease

China
Yi Luo

Recruiting

A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.

Leukemia | Graft-versus-host-disease

China
National Science Centre, Poland
Medical University of Warsaw

Recruiting

The New LC-MS/MS Method for Determination of Unbound Tacrolimus in Plasma (FreeTAC)

Kidney Transplant Rejection | Liver Transplant; Complications | Immunosuppression | Metabolism Medication Toxicity | Genetic Predisposition | Kidney Transplant; Complications | Liver Transplant Rejection

Poland
Memorial Sloan Kettering Cancer Center

Recruiting

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Hemoglobinopathies | AML | MDS | Bone Marrow Failure | ALL | Inherited Metabolic Disorders | HLH | MPD Withou Myelofibrosis | NHL or HL

United States
Peking University

Recruiting

The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

Posner Schlossman Syndrome

China
Shaymaa Mohammed El-Awady

Recruiting

Evaluation of the Clinical Outcome of Cyclosporine Short Infusion Versus Continuous Infusion Post Allogenic Stem Cell Transplantation

Allogenic Bone Marrow Transplantation

Egypt

Search clinical trials for: Calcineurine inhibitor

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