Search clinical trials for: Deficient mismatch repair

Total 4251 results

National Cancer Institute (NCI)

Completed

Olaparib in People With Malignant Mesothelioma

Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Testing Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subprotocol Z1D)

Hematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Plasma Cell Myeloma

United States
Royal Cornwall Hospitals Trust

Completed

A Retrospective Validations Microsatellite Instability (MSI) Testing v Mismatch Repair (MMR) in Gastric Adenocarcinoma

Gastric Cancer

United Kingdom
RWJ Barnabas Health at Jersey City Medical Center

Unknown

Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation

Lynch Syndrome | Endometrial Cancer | Somatic Mutation | Cancer Gene Mutation

United States
Sun Yat-sen University
The Second Affiliated Hospital of Kunming Medical University

Completed

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Colorectal Cancer Metastatic | Microsatellite Instability High | Mismatch Repair Deficiency

China
Royal Marsden NHS Foundation Trust

Unknown

SS-GCC1- Screening Study of Genetic Changes in Colorectal Cancer

Colorectal Cancer

United Kingdom
University Hospital, Montpellier

Completed

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests (PSICOM)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer
Daiichi Sankyo, Inc.
Bristol-Myers Squibb

Terminated

Antibody DS-8273a Administered in Combination With Nivolumab in Subjects With Advanced Colorectal Cancer

Colorectal Neoplasm

United States
Medical University Innsbruck

Unknown

Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation (CMMRD in NF1)

Neurofibromatosis Type 1
Lei Li

Unknown

Study of Universal Screening for Lynch Syndrome in Chinese Patients of Endometrial Cancer

Colorectal Neoplasms, Hereditary Nonpolyposis | Endometrial Neoplasms

China
Comitato Etico di Area Vasta Sud Est
Carla Caffarelli

Completed

Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study

Hypercholesterolemia
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair (HERNIIA-2)

Inguinal Hernia

Netherlands
Assaf-Harofeh Medical Center

Not yet recruiting

Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery

Scoliosis

Israel
Medtronic - MITG

Not yet recruiting

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia (RECOVER)

Hernia | Hernia, Abdominal | Hernia, Ventral | Hernia Abdominal Wall
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
Bilecik Seyh Edebali Universitesi

Not yet recruiting

The Effect of Mindfulness Training on Postoperative Pain - A Solomon Four Group Design

Postoperative Pain | Mindfulness Training | Inguinal Hernia Repair

Turkey
Muş Alparlan University

Not yet recruiting

Effectiveness of Mindfulness-based Stress Reduction Program

Stress
D. Bradley Welling, MD, PhD
Nobelpharma

Not yet recruiting

In-office Repair of Chronic Tympanic Membrane Perforations

Chronic Tympanic Membrane Perforation

United States
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

SMARCB1-Deficient Malignancies

United States
Weill Medical College of Cornell University
Intuitive Surgical

Not yet recruiting

Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair

Hiatal Hernia

United States
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment

Diffuse Large B Cell Lymphoma

Spain
National Taiwan University Hospital

Recruiting

Reinterventions of Thoracic Endovascular Aortic Repair: a Retrospective Multicenter Cohort Study

Thoracic Endovascular Aortic Repair

Taiwan
The Second Hospital of Nanjing Medical University

Recruiting

Impact of RIVP on GI Function in Patients Undergoing Surgical Repair for ATAAD

Type A Aortic Dissection

China
University of Thessaly

Not yet recruiting

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair (CoFA-TAAA)

Platelet Activation | Thoraco-abdominal Aortic Aneurysm Repair | Coagulation Factors Alterations

Greece
Zhongda Hospital

Recruiting

Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability

Respiratory Distress Syndrome | Mechanical Ventilation | Positive-Pressure Respiration

China
Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Prolgolimab Monotherapy in Locally Advanced MMR-deficient Colorectal Cancer

Colorectal Cancer

Russian Federation
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

PeLear CCC: Proyecto Latino Contra Cancer Colorectal (PeLear CCC)

Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Colon Adenocarcinoma | Colon Rectal Cancer | Hereditary Nonpolyposis Colon Cancer

United States
University of Hail

Recruiting

Controlled Active Motion vs Early Passive Mobilization for Flexor Tendons Repair

Flexor Tendon Rupture

Saudi Arabia
Top Health S.A.P.I DE C.V.
CLINICAL RESEARCH PS MEXICO

Not yet recruiting

Study to Evaluate the Effectivity and Safety of BIOSCAFF®H Compared to DuraGen®, in Patients Undergoing Dural Repair

Cerebrospinal Fluid Leakage
Cairo University

Not yet recruiting

Attitude And Practice of Egyptian Dental Practitioners Regarding Restoration Repair

Attitude | Practice | Dental Restoration Repair
University of Nove de Julho

Not yet recruiting

Action of Photodynamic Therapy on Wound Quality and Tissue Repair in the Diabetic Foot

Diabetic Foot Ulcer

Brazil
Mehmet Eşref Ulutaş
Van Training and Research Hospital

Recruiting

Comparison of Laparoscopic and Open Inguinal Hernia Repair in Elderly Patients

Pain | Postoperative Complications | Urinary Retention | Relapse

Turkey
Jonathan Bath
University of Missouri-Columbia

Not yet recruiting

Laser In Situ Fenestration Study (LIFE)

Aortic Aneurysm | Endovascular Aneurysm Repair
Assiut University

Not yet recruiting

Comparison Between External Oblique Intercostal Plane Block and the Transversus Abdominis Plane Block in Paraumbilical Hernia Repair as Analgesia for Intraoperative and Postoperative Pain.

Paraumbilical Hernia
Pirogov Russian National Research Medical University

Recruiting

The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP) (ERA-TAPP)

Primary Inguinal Hernia

Russian Federation
The Bionics Institute of Australia

Not yet recruiting

EarGenie MVP Performance Evaluation

Hearing Impaired Children

Australia
Uskudar University

Not yet recruiting

The Effect of LI4 Acupressure on Perineal Pain and Postpartum Comfort During Episiotomy Repair

Labor Pain | Perineal Pain | Postpartum Comfort
Beni-Suef University

Recruiting

Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair

Post Operative Pain

Egypt
Sohag University

Recruiting

Snodgrass Versus Grafted Snodgrass Repair in Narrow Urethral Plate in Distal Penile Hypospadias

Hypospadias

Egypt
Horsens Hospital
University of Aarhus

Recruiting

Hip Abductor Tendon Repair Versus Sham Surgery

Rupture of Hip Abductor Tendon (Disorder)

Denmark
Benha University

Recruiting

Sevoflurane and Intravenous Anesthesia in Hypospadias Repair

Emergence Delirium | Sevoflurane | Intravenous Anesthesia

Egypt
Imperial College London
University College, London; University of Southern Denmark; University of Leicester and other collaborators

Not yet recruiting

Early Endovascular Repair Versus Surveillance for Women With Small Abdominal Aortic Aneurysm (WARRIORS)

Abdominal Aortic Aneurysm
Centre Leon Berard
Groupe Français de Pneumo-Cancérologie

Not yet recruiting

FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum (FIRST-NEC)

Large Cell Neuroendocrine Carcinoma of the Lung

France
Hatice Tukenmez Kurnaz

Not yet recruiting

Effect of Local Estriol Treatment Before Vaginal Repair Surgery

Pelvic Organ Prolapse | Menopause | Vaginal Atrophy | Pelvic Floor Disorders

Turkey
Qian Qin
Janssen, LP; UT Southwestern Comprehensive Cancer Center

Not yet recruiting

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations (HARMONY)

BRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
Cairo University

Not yet recruiting

Composite Repair Using Silane Coupling Agent

Hypersensitivity | Tooth Discoloration | Dental Restoration Failure of Marginal Integrity | Tooth Fracture
Mahidol University

Not yet recruiting

Combination of Vitamin C and N-Acetylcysteine to Improve Functional Outcome After Rotator Cuff Repair

Rotator Cuff Tears
University of Roma La Sapienza

Recruiting

Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study

Inguinal Hernia | Post Operative Pain

Italy
University Hospital Muenster

Not yet recruiting

Semibranch Registry - Retrospective

Aortic Aneurysm | Endovascular Aortic Repair | Stent-Graft Endoleak

Germany
Hebei Medical University Fourth Hospital

Recruiting

Durvalumab Combined With Chemoradiotherapy for Limited Stage Small Cell Lung Cancer (Camel-01)

SCLC, Limited Stage

China

Search clinical trials for: Deficient mismatch repair

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