Search clinical trials for: Elderly subject

Total 23509 results

Celgene

Completed

A Study Being Conducted at Multiple Locations to Compare Safety and Efficacy of Three Different Regimens; (1) High-Dose Lenalidomide; (2) Lenalidomide + Azacitidine; or (3) Azacitidine in Subjects ≥ 65 Years With Newly-Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States, Canada
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Risk Factors for Cut-out After Internal Fixation of Trochanteric Fractures in Elderly Subjects.

Proximal Femoral Fracture
AstraZeneca

Completed

SAD/MAD Study to Assess Safety, Tolerability, PK & PD of MEDI1814 in Subjects With Mild-Moderate Alzheimer's Disease.

Healthy Elderly | Mild-Moderate Alzheimer's Disease

United States
Hospices Civils de Lyon

Completed

Implication of Metabolic and Genomic Modifications in Elderly Subjects (COMPALICLAMP)

Aging | Insulin Sensitivity

France
Norwegian University of Science and Technology
St. Olavs Hospital

Terminated

Exercise-induced Changes in DNA-methylation

Healthy

Norway
Seoul National University Bundang Hospital

Completed

Effectiveness of Computerized Cognitive Training in the Elderly With Cognitive Impairment (CoCoTA)

Mild Cognitive Impairment
GlaxoSmithKline

Completed

Study of Danirixin in Japanese Healthy Elderly Male Subjects

Pulmonary Disease, Chronic Obstructive

Japan
Astellas Pharma Inc

Completed

ASP8302 Single and Multiple Ascending Oral Dose Study in Non-elderly Healthy Japanese Subjects

Healthy Subjects

Japan
GlaxoSmithKline

Completed

Safety and Immunogenicity of the Zoster Vaccine GSK1437173A in Elderly Subjects

Herpes Zoster

Germany, Czechia, Sweden, Netherlands
Novartis Vaccines
Department of Health and Human Services

Completed

Safety and Immunogenicity of Two Doses of H5N1 Influenza Vaccine in Elderly Subjects

Pandemic H5N1 Influenza

United States, Australia, New Zealand, Thailand
Green Cross Corporation

Completed

A Study to Evaluate the Safety and Efficacy(Immunogenicity) of GC3114 in Elderly Healthy Subjects

Influenza, Human

Korea, Republic of
Pfizer

Completed

Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.

Healthy Subjects

Belgium
Eisai Inc.
Purdue Pharma LP

Completed

Study to Evaluate the Effect of Lemborexant Versus Placebo on Driving Performance in Healthy Adult and Elderly Subjects

Healthy Participants

Netherlands
GE Healthcare
Medpace, Inc.; Biomedical Systems; i3 Statprobe; Rules-Based Medicine, Inc.

Completed

Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure

Diabete Mellitus | Congestive Heart Failure | Chronic Renal Insufficiency

United States
Centre Hospitalier Universitaire, Amiens

Completed

The State of Play in Picardy of the Knowledge of the Elderly at Risk of Falling at Home in Terms of Prevention and Evaluation. (Epic-SaPE)

Elderly | Knowledge, Attitudes, Practice

France
GlaxoSmithKline

Completed

A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole

Pulmonary Disease, Chronic Obstructive

United States
Centre Hospitalier Universitaire de Besancon

Unknown

Subjective Factors of Polymedication in the Elderly: a Qualitative Study of the Perceptions of Patients, Relatives and Referent Physicians.(DOSAGE) (DOSAGE)

Frail Elderly Syndrome

France
Adimmune Corporation

Completed

Immunogenicity and Safety of a Trivalent Inactivated Influenza Vaccine, Formulation 2010-2011, in Non-Elderly Adult and Elderly Subjects

Influenza
Adimmune Corporation

Completed

A Trial to Assess the Immunogenicity and Safety of the Trivalent Virosomal Influenza Vaccine, Formulation of 2012-2013, in Non-Elderly Adults and Elderly Subjects

Influenza

Taiwan
National Polytechnic Institute, Mexico

Completed

Effects of COcoa Supplement in FRail Elderly Subjects (COFRE) (COFRE)

Frail Elderly Syndrome | Sarcopenia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP7713 in Healthy Non-Japanese Adult and Elderly Subjects and Healthy Japanese Adult Subjects

Healthy Volunteers

United Kingdom
University of British Columbia
Novo Nordisk A/S

Completed

Effect of GlucoNorm vs Glyburide on Post-Prandial Hyperglycemia in Elderly Subjects With Type 2 Diabetes

Type 2 Diabetes

Canada
The Hospital for Sick Children

Completed

Determination of Protein Requirement in Elderly Male Subjects >75 Yrs Old

Healthy

Canada
The Hospital for Sick Children

Completed

Determination of Protein Requirement in Elderly Male Subjects 65-75 Yrs Old.

Healthy Males 65-75 Yrs Old

Canada
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR)

Completed

Determination of Protein Requirements in Elderly Female Subjects >75 Yrs Old

Healthy Females | Protein Requirement

Canada
Trius Therapeutics LLC

Completed

Pharmacokinetics, Safety, and Tolerability of TR-701 Free Acid (FA) in Elderly Subjects

Healthy Subjects

United States
Chang Gung Memorial Hospital

Completed

Positron-Emission Tomography With Vesicular Monoamine Transporter Ligand ([18F]-DTBZ) In Healthy Elderly And Young Subjects

Healthy
Istituto Ortopedico Galeazzi

Unknown

Classification of the Sagittal Profile of the Spine in Asymptomatic Elderly Subjects (EOS60)

Aged | Asymptomatic Condition

Italy
GlaxoSmithKline

Completed

Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Four Part Study to Investigate Relative Bioavailability, Safety and Tolerability of up to 5 Oral Formulation of GSK2251052 in Order to Identify a Formulation for Further Evaluation in a Future Later Phase Study (Relative Bio)

Community-acquired Infection

Australia
GlaxoSmithKline

Completed

A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

A Clinical Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral SRT2104 Capsules Administered to Healthy Elderly Subjects for 28 Days

Atrophy, Muscular

United Kingdom
GlaxoSmithKline

Completed

Pharmacokinetics and Safety of GSK1325756 in Elderly Subjects and Adult Subjects of in the Fed and Fasted States and in the Presence of a Proton Pump Inhibitors

Nutritional Status

United States
GlaxoSmithKline

Terminated

GSK2647544 RD, DDI in Healthy Young and Elderly Volunteers

Alzheimer's Disease

United Kingdom
GlaxoSmithKline

Completed

A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of GSK2256294 in Healthy Young Males and Elderly Subjects

Pulmonary Disease, Chronic Obstructive

United States
GlaxoSmithKline

Completed

Study to Evaluate the Safety and Immunogenicity of an Investigational Pneumococcal Vaccine in the Elderly Population

Infections, Streptococcal

Belgium, Sweden, Finland
University of Guelph

Unknown

Fish Oil Supplementation, Resting Energy Expenditure, Skeletal Muscle Membrane Composition and Metabolism in Elderly Subjects.

Whole Body and Skeletal Muscle Energy Metabolism

Canada
Galapagos NV

Completed

This is a Study to Evaluate the Effect of Aging of Multiple Doses of GLPG1205 in Healthy Subjects

Healthy | Elderly

Belgium
Bial - Portela C S.A.

Completed

Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects

Parkinson Disease

Germany
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of Influenza Vaccine (Surface Antigen, Inactivated) [Ph.Eur], Formulation 2009-2010, When Administered to Non-Elderly Adult and Elderly Subjects

Influenza | Seasonal Influenza

United Kingdom
Janssen Research & Development, LLC

Completed

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly Japanese, and Healthy Younger Adult Japanese Subjects

Healthy

United States
Eisai Inc.

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics of E2027 in Healthy Adult and Elderly Subjects, and the Pharmacodynamics in Healthy Adult Subjects

Healthy Participants

United States
Novo Nordisk A/S

Completed

A Trial Investigating the Exposure of NN5401 in Young Adults and Elderly Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Austria
GlaxoSmithKline

Completed

Exploratory Study in Healthy Elderly Subjects to Collect Urine for Development of Assays to Detect S. Pneumoniae

Infections, Streptococcal
Heptares Therapeutics Limited
P1vital Limited

Completed

Phase 1 Study Investigating Effects of HTL0009936 on Cognition and BOLD fMRI Signals in Healthy Elderly Subjects

Alzheimer's Disease

United Kingdom
Novo Nordisk A/S

Completed

A Trial Investigating the Effect of NN1250 in Young and Elderly Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Austria
Tetra Discovery Partners

Completed

A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects

Alzheimer's Disease

United States
Celgene Corporation

Completed

A Study to Compare MPR With MP in Newly Diagnosed Multiple Myeloma Subjects 65 Years Old or Older.

Newly Diagnosed Multiple Myeloma

Spain, Netherlands, Austria, Australia, Italy, Russian Federation, United Kingdom, Israel, Belgium, Greece, Germany, Poland, Turkey, France, Denmark, Czech Republic, Belarus, Georgia, Ireland, Sweden, Switzerland, Ukraine
Massachusetts General Hospital

Completed

Study to Evaluate the Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Elderly Subjects

Healthy | Elderly

United States

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