Search clinical trials for: Escalation of Care

Total 436592 results

Pharmacosmos A/S

Completed

Dose-escalation Trial of the Safety, Pharmacokinetics, and Pharmacodynamics of Iron Isomaltoside (Monofer®)

Anemia | Iron Metabolism Disorders | Deficiency Diseases | Anemia, Iron Deficiency | Hematologic Disease

Japan
Columbia University
Cumberland Pharmaceuticals

Terminated

Aggressive Fever Control With Intravenous Ibuprofen After Non-traumatic Brain Hemorrhage

Fever

United States
SCRI Development Innovations, LLC
Millennium Pharmaceuticals, Inc.; Cephalon

Completed

Study to Evaluate the Combination of Bendamustine, Bortezomib and Dexamethasone (BBD) in the First-Line Treatment of Patients With Multiple Myeloma Who Are Not Candidates for High Dose Chemotherapy

Multiple Myeloma

United States
Cornerstone Pharmaceuticals

Terminated

A Phase I/II Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Gemcitabine in Cancer Patients

Cancer | Pancreatic Cancer | Pancreatic Carcinoma

United States
Millennium Pharmaceuticals, Inc.

Completed

Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer

Metastatic Solid Tumors

United States, Spain, United Kingdom
Galera Therapeutics, Inc.

Completed

A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck

Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx

United States
SCRI Development Innovations, LLC
Millennium Pharmaceuticals, Inc.; Cephalon

Completed

Trial of Bendamustine, Bortezomib, and Rituximab in Patients With Previously Untreated Low Grade Lymphoma

Lymphoma

United States
Threshold Pharmaceuticals

Unknown

Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Saint Francis Care

Terminated

Intravenous Acetaminophen Use With Bariatric Surgery on Morbidly Obese Patients

Pain | Obesity

United States
Bastyr University
University of Washington; Fred Hutchinson Cancer Center

Withdrawn

A Phase 1b Dose Escalation Trial of PSK®/Placebo With Docetaxel to Treat Metastatic Castration-resistant Prostate Cancer

Prostatic Neoplasms

United States
AstraZeneca
Nektar Therapeutics

Completed

A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)

Opioid Induced Constipation (OIC)

United States
Neuralstem Inc.

Unknown

Dose Escalation and Safety Study of Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States
Sangamo Therapeutics

Completed

Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients

HIV Infections | HIV Infection

United States
National Cancer Institute (NCI)

Terminated

Bortezomib, Liposomal Doxorubicin Hydrochloride, Dexamethasone, and Cyclophosphamide in Treating Patients With Multiple Myeloma That Relapsed After Autologous Stem Cell Transplant

Refractory Multiple Myeloma

United States
Seagen Inc.

Completed

A Phase 1 Dose-escalation Trial of SGN-75 in CD70-positive Non-Hodgkin Lymphoma or Renal Cell Carcinoma

Lymphoma, Non-Hodgkin | Carcinoma, Renal Cell

United States
Winthrop University Hospital

Completed

Use Of Procalcitonin Level For Guidance of The Treatment of Suspected Community Acquired Pneumonia

Pneumonia | Radiographic Lung Infiltrates

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

IV Busulfan Plus Bortezomib Conditioning Regimen for Second Autologous Stem Cell Transplant in Multiple Myeloma Patients

Multiple Myeloma

United States, Canada
Threshold Pharmaceuticals

Unknown

Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors (TH-CR-410)

Gastrointestinal Stromal Tumors | Advanced Renal Cell Carcinoma | Pancreatic Neuroendocrine Tumors

United States
Gilead Sciences

Completed

A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients

HIV Infections

United States
Asan Medical Center

Unknown

Strategy to Improve Adherence of Roflumilast

Chronic Obstructive Pulmonary Disease

Korea, Republic of
Seagen Inc.
Agensys, Inc.

Completed

A Phase 1 Dose Escalation Trial of ASG-5ME in Pancreatic or Gastric Adenocarcinoma

Pancreatic Neoplasms | Gastric Neoplasms

United States
Accelerated Community Oncology Research Network
Bayer

Terminated

Randomized Study of Sorafenib Dose Escalation in Patients With Previously Untreated Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma

United States
Western Sydney Local Health District
St George Hospital, Australia

Completed

Study of Tamoxifen Dose Escalation in Breast Cancer Patients With CYP2D6 Polymorphisms (TADE)

Breast Cancer | CYP2D6 Polymorphism

Australia
QLT Inc.

Completed

Dose Escalation Study With QLT0074 for Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

United States, Canada
Bristol-Myers Squibb

Completed

A Study of Tanespimycin (KOS-953) in Patients With Multiple Myeloma in First Relapse (BMS TIME-1)

Multiple Myeloma

United States, Canada
Westat
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type I (NPTUNE 02)

Spinal Muscular Atrophy Type I

United States
Westat
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Types II or III (NPTUNE01)

Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type III

United States
Bristol-Myers Squibb

Completed

A Dose-Escalation Study of MDX-1100 in Patients With Active Ulcerative Colitis

Ulcerative Colitis

United States
Ionis Pharmaceuticals, Inc.

Completed

Placebo Controlled, Dose Escalation Study in Subjects With Type 2 Diabetes Mellitus Being Treated With Sulfonylurea

Type 2 Diabetes Mellitus

Poland, Romania, Russian Federation
Cell Genesys

Completed

Dose Escalation and Efficacy Trial of GVAX® Prostate Cancer Vaccine

Prostate Cancer

United States
Elizabeth Austen Lawson

Not yet recruiting

Identifying Oxytocin Deficiency in Adults With Pituitary Disease

Oxytocin Deficiency | Arginine Vasopressin Deficiency
University of Kansas Medical Center
National Institute of Nursing Research (NINR); National Institutes of Health...

Not yet recruiting

Health Equity and Rural Education (HERE!) Clinical Trial (HERE)

Behavioral Symptoms | Educational Problems | Social Determinants of Health | Community Health Workers

United States
Mingfu Wu
Peking Union Medical College Hospital; Peking University Third Hospital; Southwest... and other collaborators

Recruiting

Pelvic Floor Rehabilitation of Female Pelvic Floor Dysfunction

Pelvic Organ Prolapse | Pelvic Floor Disorders

China
University of Illinois at Chicago
Rocky Mountain Human Services

Not yet recruiting

Exploratory Trial of a Pediatric Web-Based Care Planning Guide (PROSPECT+)

Developmental Disabilities | Developmental Delay
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR)

Recruiting

Feasibility of CALM in Patients With Ovarian Cancer

Ovarian Cancer | Patient Satisfaction

Canada
Aveiro University
Fundação para a Ciência e a Tecnologia

Not yet recruiting

Shedding Light on a Forgotten Workforce: Loved Ones of People With Chronic Respiratory Diseases

Chronic Respiratory Disease

Portugal
Universität des Saarlandes

Recruiting

Adherence to Medication in Patients With Acute Decompensated Heart Failure (ADHF-ED)

Acute Decompensated Heart Failure

Germany
Hospices Civils de Lyon

Not yet recruiting

The Prevalence of the Aortic to Radial Pressure Gradient in States of Shock, Outside the Context of Cardiac Surgery, a Prospective Study (PARECHOC)

Shock

France
Helse Møre og Romsdal HF

Not yet recruiting

ATTR Cardiac Amyloidosis in a Selected Population

Carpal Tunnel Syndrome | Cardiac Amyloidosis | ATTR Amyloidosis Wild Type | ATTR Gene Mutation
German University in Cairo
Prof. Mohamed Hassan Solayman, Clinical pharmacy Department, German University... and other collaborators

Not yet recruiting

Effect of Vitamin D Supplementation on Mental Health: An Exploratory Study on A University Students Suffering From Vitamin D Deficiency

Psychiatric Disorder
University of Parma
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Federico II University; University... and other collaborators

Recruiting

Use of miRNAs in Growth Hormone Deficiency (GHD) (GH-miRNA2)

Growth Hormone Deficiency

Italy
NYU Langone Health
Massachusetts General Hospital; University of Pennsylvania; OhioHealth

Not yet recruiting

Multi-Center Project: Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)

Heart Failure

United States
Burdur Mehmet Akif Ersoy University

Not yet recruiting

Knowledge Levels and Experiences of Intensive Care Nurses on the Prevention of Pressure Sores: Mixed Method

Critical Care | Pressure Ulcer | Nurses
Seoul St. Mary's Hospital

Not yet recruiting

Comparison of Clinical Outcomes According to High-protein Provision in Critically Ill Patients After Abdominal Surgery

Protein Malnutrition

Korea, Republic of
Port Said University

Recruiting

Determining the Prevalence of Primary and Secondary Central Line Associated Blood Stream Infection (CLABSI) at the Tertiary Care Hospital (Microbiology)

Central Line-associated Bloodstream Infection (CLABSI)

Egypt
Kenyatta National Hospital
National Institute of Mental Health (NIMH)

Not yet recruiting

Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics (IPMH)

Depression, Anxiety | Antenatal Depression | Postnatal Depression

Kenya
Guiding Right, Inc.
University of California, San Diego

Recruiting

LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence (LPP Plus)

HIV/AIDS | Mental Health Issue

United States
University of Manchester
Northern Care Alliance NHS Foundation Trust; Manchester University NHS Foundation...

Not yet recruiting

Piloting the Attention Training Technique for Post-Stroke Emotionalism

Stroke | Crying | Pseudobulbar Affect | Emotionality | Lability Emotional

United Kingdom
Vanderbilt University Medical Center
National Institute of Mental Health (NIMH)

Not yet recruiting

Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency (iPEACE)

Parents | Self Efficacy | Psychiatric Emergency | Mental Health Literacy

Search clinical trials for: Escalation of Care

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