Search clinical trials for: Evaluation of QT Interval

Total 432455 results

Connect Biopharma Australia Pty Ltd

Completed

A Study to Investigate the Effects of CBP-307 on the Heart Rate-corrected QT Interval (QTc) in Healthy Subjects

Autoimmune Diseases

Australia, United States
Daiichi Sankyo Co., Ltd.
AstraZeneca

Completed

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer

Malignant Neoplasm of Breast

Japan
Pfizer

Completed

Evaluating QTc, PK, Safety of Gemtuzumab Ozogamicin (GO) in Patients With CD33+ R/R AML

Pharmacokinetics | Safety | ECG

Canada, Spain, United States, Hungary, Poland, United Kingdom
Concert Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers

Healthy Volunteers

United States
University Hospital, Bordeaux

Completed

Evaluation of Non-invasive Measurement of Electrophysiological "HV" Interval Using a High-density and High-fidelity Signal Averaging ECG Device (BIOSEMI-HV)

Electrocardiogram | Cardiac Electrophysiology

France
Children's Hospital of Fudan University

Completed

The Setting and Effect Evaluation of QT in NICU

Very Low Birth Weight Infant

China
University of Sunderland
Sheffield Hallam University; Newcastle University; Teesside University

Suspended

Exercise Induced QT Interval Changes in Response to Intermittent and Continuous Graded Exercise Tests

Qt Interval, Variation in

United Kingdom
LG Chem

Completed

Thorough QT (TQT) Study to Evaluate the Effect of LC350189 on Cardiac Repolarization in Healthy Male and Female Subjects

Hyperuricemia | Gout | Qt Interval, Variation in

United States
Alexion Pharmaceuticals
Celerion

Completed

A Study of the Cardiac Effects of ALXN2050 in Healthy Adults

Healthy

United States
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy Adults

QT Intervals Changes | QTc Intervals Changes

United Kingdom
Yonsei University

Completed

The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Living Donor Liver Transplantation Under Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial

Liver Cirrhosis(Who Will Undergo Planed Liver Transplantation)

Korea, Republic of
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of the Cardiac Effects of Danicopan in Healthy Adults

Healthy

United States
Odonate Therapeutics, Inc.

Terminated

The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
BioMarin Pharmaceutical

Completed

A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects

Phenylketonuria

United States
University Hospital, Bordeaux

Completed

Study of Arrhythmia and ECG Abnormalities in Patients With COVID-19 (RYTHMO-COV)

Arrhythmia | SARS-CoV-2 Infection

France
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Completed

5-HT3 Antagonists (Antiemetics) and Cardiac Safety

Adverse Reaction to Other Drugs and Medicines

Canada
Richmond Research Institute
Richmond Pharmacology Limited

Completed

Effect of Glucose on QTc Interval in Type 1 Diabetes

Diabetes

United Kingdom
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of ACP-196 on the Heart Rate-corrected QT Interval in Healthy Adult Participants

Healthy Volunteers

United States
QT Ultrasound LLC

Completed

Case Collection Study in the Evaluation of Doubling Time Rates in Non-Suspicious Breast Masses Using QT Ultrasound Technology (EVALUATE)

Breast Fibroadenoma

United States
Nantes University Hospital

Completed

CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death (IQARE-SCD)

Sudden Cardiac Death

France
I.M. Sechenov First Moscow State Medical University

Completed

Evaluation of the Effect of IHHT on Vascular Stiffness and Elasticity of the Liver Tissue in Patients With MS.

Metabolic Syndrome | Vascular Stiffness | Liver Fibroses | Trimethylamine N-oxyde | Toll-like Receptors

Russian Federation
Gilead Sciences

Completed

Study to Evaluate the Effect of Eleclazine on QT, Safety, and Tolerability in Participants With Long QT2 Syndrome

LQT2 Syndrome

United States
Nowodworskie Centrum Medyczne
Medical University of Warsaw

Completed

Obstructive Sleep Apnea Destabilizes Myocardial Repolarization Homogeneity

Obstructive Sleep Apnea | Obesity, Abdominal | Heart Rhythm Disorder
Yonsei University

Completed

The Association of Cardiac Ion Channel Related Gene Polymorphism and Prolonged QTc Interval After Endotracheal Intubation

Emergence Delirium

Korea, Republic of
Yonsei University

Completed

Effect of Ramosetron on Heart Rate-corrected QT Interval During Robot-assisted Laparoscopic Prostatectomy With Steep Trendelenburg Position

Prostate Cancer

Korea, Republic of
Rabin Medical Center

Unknown

Voriconazole-Induced QT Interval Prolongation: A Prospective Study

Voriconazole Induced QT Interval Prolongation

Israel
Aziende Chimiche Riunite Angelini Francesco S.p.A
Cross Research S.A.; eResearch Technology, Inc.

Completed

Effects of Three Single Oral Doses of Trazodone on the QTc Interval Duration in Healthy Volunteers

Healthy

Switzerland
Hoffmann-La Roche

Completed

Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects

Healthy Volunteers

United States
Beni-Suef University

Completed

Effect of Ciprofloxacin Versus Levofloxacin on QTc-interval and Dysglycemia

QTc Prolongation, Hyperglycemia, Hypoglycemia

Egypt
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of GMI-1070 on Qtc Intervals in Healthy African-American Adult Subjects

Healthy

United States
Hospital Clinic of Barcelona
University Hospital, Antwerp; Academisch Medisch Centrum - Universiteit van... and other collaborators

Unknown

COVIDAR - Arrhythmias in COVID-19 (COVIDAR)

Atrial Fibrillation | Arrhythmia | COVID | Atrioventricular Block | Ventricular Arrythmia | Qt Interval, Variation in | Bradyarrhythmia | Torsades de Pointe Caused by Drug

Spain, Belgium, Italy, Netherlands, United Kingdom
Matilde Zaballos

Unknown

Effects on the Qt Interval of COVID-19 Coronavirus Infection (QT-COVID-19)

Coronavirus Infection | Intensive Care Patients

Spain
Assistance Publique Hopitaux De Marseille

Completed

QT-Logs : Artificial Intelligence for QT Interval Analysis of ECG From Smartwatches in Patient Receiving Treatment for Covid-19 (QT-Logs)

COVID-19

France
Bangladesh Medical Research Council (BMRC)

Unknown

Performance Evaluation of RealDetect™ COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus

High Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR Kit

Bangladesh
Zydus Therapeutics Inc.

Completed

A Study to Evaluate the Effect of Saroglitazar Magnesium on the QTc Interval in Healthy Volunteers

Healthy

India
Bayer
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

Coronary Artery Disease

Germany, Moldova, Republic of, Netherlands
Northeast Iowa Medical Education Foundation

Completed

Pharmacist Use of ECG to Inform Drug Therapy Decisions for Patients Receiving QT Prolonging Medications

Torsades de Pointes | Qt Interval, Variation in | Torsades de Pointe Caused by Drug (Disorder)

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)

Healthy

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
AstraZeneca
Parexel

Completed

A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers

Solid Tumors

United States
Andre Barreto Pereira
Novartis

Completed

Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant

Immunosuppression | Renal Transplant Rejection

Brazil
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

CiPA Phase 1 ECG Biomarker Validation Study

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation

United States
Duke University
Bristol-Myers Squibb

Terminated

INTERVAL: Ipilimumab and Nivolumab Combination Therapy: A Study of a Supervised or Semi-Supervised Exercise InteRVention or Usual Care With Functional Capacity and Quality of Life Evaluations in Subjects With Advanced or Metastatic RenAL Cell Carcinoma (INTERVAL)

Metastatic Renal Cell Carcinoma

United States
William S. Middleton Memorial Veterans Hospital
University of Wisconsin, Madison

Completed

Prospective Evaluation of an Extended Interval of INR Follow-up in a VA Anticoagulation Service

Anticoagulation
PharmaMar

Completed

Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid Tumors

Solid Tumors

Spain, United States
NorthSea Therapeutics B.V.

Completed

A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval

Dyslipidemias

United Kingdom
Celgene

Completed

A Phase I Study to Assess the Safety, Pharmacokinetics, and Potential Effects of Amrubicin on the QT/QTc Interval in Cancer Patients With Advanced Solid Tumors.

Advanced Solid Tumors

United States
Pfizer

Completed

A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin

Healthy Volunteers

Belgium
University of the Pacific

Completed

The Effect of Energy Drink on Cardiovascular Variables: A Randomized Controlled Trial

Cardiovascular Diseases

United States
NorthShore University HealthSystem

Unknown

Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

EKG-QT Prolongation

United States

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