Search clinical trials for: First in Man

Total 467634 results

Elsan

Not yet recruiting

Unexpected Positive Cultures in Rotator Cuff Revision Surgery (POCICO)

Rotator Cuff Repair

France
China Medical University, China

Not yet recruiting

Durvalumab Combined With Surufatinib as Maintenance Therapy in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer

China
Ping Li,MD

Not yet recruiting

Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Non-Alcoholic Fatty Liver Disease
Peking University First Hospital
Peking University

Recruiting

Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival

Delirium | Hypothermia | Long-term Survivors | Cancer Surgery

China
Qinying Ma

Recruiting

Study on the Therapeutic Effect and Mechanism of Transcranial Plasma Stimulation in the Treatment of Chronic Insomnia

Chronic Insomnia Disorder

China
Patient Organization Veronica

Recruiting

HPV DNA Self-sampling in a General Practitioner's Office. (ASTRA)

Cervical Cancer | HPV Infection | Precancerous Lesion

Czechia
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Comparison of the Application of Robot-assisted Laparoscopic Pathways in Radical Cystectomy

Bladder Cancer

China
Guangdong Raynovent Biotech Co., Ltd

Recruiting

Pharmacokinetics of ZSP1273 in Participants With Severe Kidney Disease

Kidney Impairment

China
Suzhou Municipal Hospital
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

The Effect of LIPUS on the Maturation of Newly Constructed Autogenous AVF

Uremia; Chronic

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Chinese Medicine Treatment of Adolescent Sleep Disorders and Sleeping Pills Withdrawal

Sleep Disorder | Traditional Chinese Medicine

China
Huashan Hospital
China Alliance for Rare Diseases; National Center for Neurological Disorders... and other collaborators

Recruiting

Myasthenia Gravis Registry in China

Myasthenia Gravis

China
Peking University First Hospital

Recruiting

The Effect of Potassium Lowering Drugs on Cardiac Electrical Stability in Hemodialysis Patients (ART Study)

Cardiac Arrhythmia | Potassium Imbalance | Dialysis; Complications

China
The First Hospital of Jilin University

Recruiting

Effect of ICCAUT Strategy on Postoperative Urinary Dysfunction After Radical Rectal Cancer Surgery (ICCAUT-1)

Rectal Cancer | Urinary Dysfunction | Urinary Retention Postoperative | Urinary Catheterization

China
MediLink Therapeutics (Suzhou) Co., Ltd.

Recruiting

A Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Patients With mCRPC

Metastatic Castration-resistant Prostate Cancer (mCRPC)

China
Shanghai Changzheng Hospital
Shanghai Zhongshan Hospital; The First Affiliated Hospital of Guangzhou Medical... and other collaborators

Recruiting

Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)

Prostate Adenocarcinoma | Localized Prostate Carcinoma

China
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis (TRuE-AD4)

Atopic Dermatitis

Germany, Poland, United States, Spain, United Kingdom, Italy, Belgium, Canada, Netherlands, Australia, Bulgaria, France, Switzerland, Hungary, Korea, Republic of
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Australia, France, Taiwan, Hungary, Korea, Republic of, Spain, Switzerland, China, Japan, Belgium, Canada, Germany, Italy, Poland, Romania, United Kingdom, Czechia, Denmark, Greece, Norway, Slovakia, Netherlands
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China

BPPV | Vertigo | Vertigo, Peripheral

China
RemeGen Co., Ltd.

Recruiting

Disitamab Vedotin in the Treatment With HER2- Expression, Subjects With Locally Advanced or Metastatic Castration-resistant Prostate Cancer

Castration-resistant Prostate Cancer

China
University of Manitoba
Boehringer Ingelheim; Research Manitoba; First Nations Health and Social Secretariat... and other collaborators

Not yet recruiting

Virtual Kidney Check and Follow-up

Kidney Disease, Chronic
First Affiliated Hospital, Sun Yat-Sen University
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

The Characteristics, Treatment Patterns and Prognosis of Chinese Male Breast Cancer: A Real-world Study

Breast Cancer

China
Hospital of South West Jutland
Novo Nordisk A/S

Recruiting

Recovering From Bariatric Surgery: the Effects of Early Initiated and Supervised Mobilization

Physical Activity | Postoperative Pain, Acute | Postoperative Pain, Chronic | Bariatric Surgery | Mobilization

Denmark
Mclean Hospital
Baszucki Family Foundation

Recruiting

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

Schizoaffective Disorder | Psychosis | Bipolar I Disorder

United States
Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography

Chronic Kidney Diseases | Left Ventricular Systolic Dysfunction

China
Jemincare

Recruiting

Evaluate the Efficacy and Safety of JMKX000623 in Participants With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

China
Bayer

Recruiting

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC) (PAnTHA)

Advanced Metastatic Castration-resistant Prostate Cancer | Prostate Specific Membrane Antigen (PSMA) Expression

Canada, United Kingdom, Belgium
Juno Therapeutics, Inc., a Bristol-Myers Squibb...
Celgene Corporation

Recruiting

A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis or Progressive Forms of Multiple Sclerosis

Multiple Sclerosis

United States, Belgium, France, Germany, Spain, United Kingdom, Italy
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

A Clinical Study of T3011 in Combination With PD-1/PD-L1 Inhibitors in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

China
Fudan University

Recruiting

Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma

Kidney Cancer | Renal Cell Carcinoma | Renal Clear Cell Carcinoma

China
First Affiliated Hospital of Zhejiang University

Recruiting

Transcranial Alternating Current Stimulation in Patients With Disorders of Consciousness

Consciousness Disorders

China
Junhao Zheng

Recruiting

Is Re-examination of Urine Culture Necessary for Patients With Preoperative Positive Results in Predicting Infectious Complications Related to Mini-Percutaneous Nephrolithotomy?

Sepsis | Kidney Calculi | Urinary Tract Infections

China
Janssen Research & Development, LLC

Recruiting

A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG) (SunRISe-5)

Non-Muscle Invasive Bladder Neoplasms

Korea, Republic of, United States, United Kingdom, China, Japan, Brazil, Argentina
Janssen Research & Development, LLC

Recruiting

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide (MonumenTAL-6)

Relapsed or Refractory Multiple Myeloma

Germany, Korea, Republic of, Italy, France, Japan, Israel, Belgium, Denmark, Sweden, China, Spain, Czechia, Poland, Australia, Netherlands, Argentina, Canada, United Kingdom, Greece, Brazil, India
Peking University Cancer Hospital & Institute

Recruiting

Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer

Rectal Cancer

China
Perha Pharmaceuticals
Fondation Jérôme Lejeune; European Innovation Council; France 2030 program

Recruiting

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease (LEUCETTA)

Healthy Volunteers | Down Syndrome | Alzheimer's Disease

France
Yi Han
Qianfoshan Hospital

Recruiting

Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Heart Failure | Efficacy | Safety | Levosimendan | Milrinone

China
Peking University First Hospital

Recruiting

A Clinical Study on the Whole-course Management (BCD-KPD-AutoHSCT) Scheme for Patients With RIMM

Multiple Myeloma | Renal Injury

China
Daiichi Sankyo
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer (IDeate-Lung02)

Small Cell Lung Cancer

United States, Spain, Germany, Hungary, China, Italy, Korea, Republic of, United Kingdom, France, Belgium, Japan, Taiwan, Netherlands, Australia, Portugal, Poland, Turkey, Switzerland, Brazil, Canada, Romania
Jining First People's Hospital

Recruiting

Study on Biomarkers of Postoperative Delirium in Elderly Cardiac Surgery Patients

Delirium

China
Jin Lu, MD

Recruiting

Optimize First-line Treatment for AL Amyloidosis With t (11; 14)

AL Amyloidosis | Amyloidosis; Systemic

China
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin (ACHIEVE-2)

Type 2 Diabetes

Taiwan, United States, China, Mexico, Germany, Poland
AstraZeneca

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors (CYCAD-1)

ER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)

United States, United Kingdom, Korea, Republic of, Australia, Spain
Centre Hospitalier Universitaire de Saint Etienne
Takeda France

Not yet recruiting

Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration. (VEDIAN)

Crohn's Disease

France
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Intermittent Darolutamide Treatment in the Triple Therapy of mHSPC

Metastatic Prostate Cancer | Intermitent Anti-androgen Therapy

China
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Immune Thrombocytopenia

China
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

The Effect of Gastric Emptying on Blood Glucose Profile of Type 1 Diabetes Mellitus and Its Therapeutic Strategies

Diabetes

China
Zhejiang Provincial People's Hospital
Taizhou Hospital; The Fourth Affiliated Hospital of Zhejiang University School... and other collaborators

Recruiting

Steroid Diabetes in Patients With Kidney Disease

Nephrotic Syndrome

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, First-in-human Study of VX-828

Cystic Fibrosis

United States
The First Affiliated Hospital of Xiamen University

Recruiting

Mobile Internet Healthcare and Three Disciplines Co-management Intervention for Overweight/Obese Prediabetic Patients

Prediabetes | Weight Management | Overweight/Obesity

China

Search clinical trials for: First in Man

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