Search clinical trials for: Intravitreal injection

Total 11357 results

University of Wisconsin, Madison

Completed

Control of Pain in Intravitreal Injections Using Topical NSAIDs (COPIVIN)

Intravitreal Injections | IVI

United States
Bayer

Completed

Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice

Wet Age-related Macular Degeneration

India
Ribomic USA Inc

Completed

A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration (RAMEN)

Exudative Age-related Macular Degeneration

United States
Bayer
Regeneron Pharmaceuticals

Completed

Observational Study to Assess Intravitreal Aflibercept Injections Used in a "Treat and Extend" Regimen in Treatment-naïve Wet Age-related Macular Degeneration Patients (ASTERIA)

Wet Age-related Macular Degeneration

Switzerland
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial Kit

Neovascular Age-related Macular Degeneration (nAMD)

United States
Chang Gung Memorial Hospital

Enrolling by invitation

The Analysis of Association of Retinopathy of Prematurity, Gut Microbiome Profile, and Systemic Inflammation

Retinopathy of Prematurity | Microbiome

Taiwan
Damascus University

Completed

Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.

Cataract | Intravitreal Injection | Diabete Type 2 | Triamcinolone Acetonide

Syrian Arab Republic
University of Oklahoma

Completed

The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections

Age-Related Macular Degeneration | Diabetic Macular Edema | Intravitreal Injection | Ocular Rinse | Cystoid Macular Edema

United States
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison

Completed

A Randomized, Double-masked, Multicenter,Sham-controlled, Safety and Efficacy Study of KH902 in Patients With Wet AMD (PHOENIX)

Neovascular Age-related Macular Degeneration

China
Mayo Clinic
Research to Prevent Blindness; VitreoRetinal Surgery, PA

Completed

Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections

Pain, Postoperative | Age-related Macular Degeneration | Diabetic Macular Edema | Injection Site | Injection Site Infection

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Completed

Intravitreal Conbercept Injection in Patients With Myopic Choroidal Neovascularization

Myopic Choroidal Neovascularisation

China
Instituto Universitario de Oftalmobiología Aplicada...
Fondo de Investigacion Sanitaria

Completed

Efficacy and Safety Study of Intravitreal Triamcinolone to Treat Diffuse Diabetic Macular Edema

Diabetes Mellitus | Macular Edema

Spain
Instituto Universitario de Oftalmobiología Aplicada...

Completed

Initial Treatment With Bevacizumab in Choroidal Neovascularization Associated to High Myopia (BENEMCOR)

Choroidal Subfoveal/Juxtafoveal Neovascularization in High Myopia

Spain
Hoffmann-La Roche

Completed

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of RO7303359 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

Geographic Atrophy

United States
Novartis Pharmaceuticals

Terminated

Brolucizumab Treatment Experience Study of Patients With nAMD in UK Routine Clinical Practice (BESRA)

Neovascular Age-related Macular Degeneration

United Kingdom
Retina Vitreous Associates of Florida
Ocular Therapeutix, Inc.

Terminated

Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections (DETeR)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

United States
Bayer

Completed

Study to Gather Information on the Safety and Use of Aflibercept Injections Into the Eye for the Treatment of Eye Disorders in Mexican Routine Clinical Practice (MAIA)

Retinal Disease

Mexico
IRCCS San Raffaele

Completed

Retrospective Observational Comparison Study Between Ustekinumab and Tofacitinib as Third Line Therapy in a Multicenter Cohort of Patients With Refractory Ulcerative Colitis.

Ulcerative Colitis

Italy
Aerie Pharmaceuticals

Completed

A Study Assessing AR-13503 Implant in Subjects With nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Dar El Oyoun Hospital
Cairo University

Completed

Focal Laser Single Intravitreal Ranibizumab Retinal Artery Macroaneurysm. (RAM)

Retinal Artery Macroaneurysm

Egypt
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Zagazig University
Cairo University

Completed

Intravitreal Ranibizumab Injection for Aggressive Versus Type 1 Prethreshold Retinopathy of Prematurity

Retinopathy of Prematurity | Ranibizumab | Retina Disease

Egypt
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections (MERLIN)

Age-Related Macular Degeneration

United States, Puerto Rico
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central...

Completed

Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Myopia (COAST_UAmCNV)

Pathologic Myopia

Ukraine
ProQR Therapeutics

Terminated

Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, United Kingdom
ProQR Therapeutics

Terminated

An Open-Label Extension Study to Evaluate Safety & Tolerability of QR-421a in Subjects With Retinitis Pigmentosa (HELIA)

Retinitis Pigmentosa | Usher Syndrome Type 2

United States, Canada, France
Genentech, Inc.

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of FCFD4514S in Patients With Geographic Atrophy

Geographic Atrophy
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Prefilled Syringe

Neovascular Age-related Macular Degeneration (nAMD)

United States
Gemini Therapeutics, Inc.

Terminated

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration

Macular Degeneration | Retinal Degeneration | Neovascular Age-related Macular Degeneration | Retinal Disease

United States
Peking Union Medical College Hospital
Beijing Bethune public welfare fund

Terminated

Effects of Conbercept in Refractory Uveitic Macular Edema and VEGF

Uveitis | Macular Edema | Vascular Endothelial Growth Factor | Effect of Drugs

China
Shahid Beheshti University of Medical Sciences

Active, not recruiting

Additional Effect of Subthreshold Micropulse Laser to Intravitreous Injection of Bevacizumab on Diabetic Macular Edema

Diabetic Macular Edema

Iran, Islamic Republic of
ONL Therapeutics

Completed

A Study to Evaluate the Safety and Tolerability of ONL1204 in Patients With Macula-off, Rhegmatogenous Retinal Detachment

Rhegmatogenous Retinal Detachment - Macula Off

Australia
Hoffmann-La Roche

Completed

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration (Archway)

Neovascular Age-Related Macular Degeneration

United States
American Genomics, LLC

Completed

A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution

Anesthesia, Local

United States
Gemini Therapeutics, Inc.

Terminated

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration

Macular Degeneration | Retinal Degeneration | Geographic Atrophy | Dry Age-related Macular Degeneration | Retinal Disease

United States
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
First Affiliated Hospital of Chongqing Medical...

Enrolling by invitation

Efficacy and Safety of Intravitreal Conbercept With Modified Treat-and-Extend Regimens in Exudative AMD (IIT-A)

Exudative Age-Related Macular Degeneration

China
Nantes University Hospital

Completed

Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema (TRIOZ)

Inflammatory Macular Edema

France
Recens Medical, Inc.

Completed

Long Term Safety of Cooling Anesthesia for Intravitreal Injection (COOL-2)

Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Anesthesia, Local | Intravitreal Injection

United States
Yale University

Terminated

Tofacitinib for Treatment of Moderate COVID-19 (I-TOMIC)

COVID-19 Pneumonia

United States
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central...

Completed

Triamcinolone Acetonide in Patients With Serous Pigment Epithelial Detachment (COAST_UA_AMD)

Age-Related Macular Degeneration

Ukraine
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KINGFISHER)

Diabetic Macular Edema

United States, Hungary, Israel, Slovakia, Puerto Rico
GenSight Biologics

Active, not recruiting

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year (REFLECT)

Leber Hereditary Optic Neuropathy

Belgium, Spain, United States, France, United Kingdom, Taiwan, Italy
GenSight Biologics

Completed

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation (RESCUE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, France, Germany, Italy
Peking University People's Hospital
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Completed

The Effect of IVA for Preventing Postvitrectomy Hemorrhage in PDR

Proliferative Diabetic Retinopathy

China
Annexon, Inc.

Active, not recruiting

A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy (ARCHER)

Geographic Atrophy

United States, Australia, New Zealand
Emad Abdel Aal Saliem

Completed

Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract Surgery

Pharmacological Action

Egypt
Opthea Limited

Completed

A Dose Ranging Study of OPT-302 With Aflibercept for Persistent Diabetic Macular Edema

Diabetic Macular Edema

United States, Israel, Australia, Latvia
Peking University People's Hospital

Completed

Efficacy and Safety Comparison of IVR and IVC Before Vitrectomy in Proliferative Diabetic Retinopathy

Proliferative Diabetic Retinopathy

China
Peking University People's Hospital

Completed

Comparison of Surgery Outcome Between Preoperative IVR and Intraoperative IVR in PPV for PDR

Proliferative Diabetic Retinopathy

China

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