Search clinical trials for: Mucopolysaccharidosis (mps) ii

Total 31676 results

REGENXBIO Inc.

Active, not recruiting

CAMPSIITE™ RGX-121 Gene Therapy in Subjects With MPS II (Hunter Syndrome)

Mucopolysaccharidosis Type II (MPS II)

United States, Brazil
Allievex Corporation

Completed

A Treatment Study of Mucopolysaccharidosis Type IIIB (MPS IIIB)

Mucopolysaccharidosis Type IIIB | MPS III B

United States, Taiwan, Spain, Colombia, Germany, United Kingdom, Turkey
AO GENERIUM

Recruiting

A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II

Metabolic Diseases | Mucopolysaccharidosis Type II

Russian Federation
Pfizer

Completed

Long-Term Open-Label Extension Trial for Subjects Completing the Phase 3 Trial of Fesoterodine (SP583) for the Treatment of Overactive Bladder Syndrome

Overactive Bladder Syndrome

Germany
Pfizer

Completed

A Multicenter Trial to Investigate Fesoterodine Sustained Release in Overactive Bladder Syndrome

Overactive Bladder Syndrome

Germany
Genzyme, a Sanofi Company
BioMarin/Genzyme LLC

Completed

Immune Tolerance Study With Aldurazyme® (Laronidase)

Mucopolysaccharidosis I

Brazil, Russian Federation
Pfizer

Completed

Long-Term Open-Label Extension Trial for Subjects Completing the Phase 3 Trial of Fesoterodine (SP584) for the Treatment of Overactive Bladder Syndrome

Overactive Bladder Syndrome

United States
Pfizer

Completed

Trial to Investigate the Efficacy, Tolerability and Safety of Fesoterodine Sustained Release in Subjects With Overactive Bladder Syndrome

Overactive Bladder
Mustafa Kemal University

Recruiting

Myofascial Pain Syndrome and Dextrose Prolotherapy

Efficacy of Dextrose Prolotherapy in Myofascial Pain Syndrome

Turkey
Vilnius University
University of Cagliari

Completed

Factors Influencing the Composition of Human Milk

Breast Milk Collection

Lithuania
University of Minnesota
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Longitudinal Studies of Brain Structure and Function in MPS Disorders

Mucopolysaccharidosis Type I | Mucopolysaccharidosis Type II | Mucopolysaccharidosis Type VI | Mucopolysaccharidosis Type IV | Mucopolysaccharidosis Type VII

United States, Canada
Green Cross Corporation

Completed

A Study of GC1111 in Hunter Syndrom Patients

Hunter Syndrome

Korea, Republic of
Bausch & Lomb Incorporated

Completed

A Safety and Effectiveness Study of a New Contact Lens Cleaning and Disinfecting Solution

Contact Lens Wear

United States
Pfizer

Completed

Two Phase Extension Trial of SP668 to Investigate the Safety and Tolerability of Sustained Release Fesoterodine in Subjects With Overactive Bladder: a Double-Blind Phase Followed by an Open-Label Extension Phase

Overactive Bladder

United States
Medinova AG

Completed

Efficacy and Tolerability of Hirudoid Cream in Prophylaxis and Treatment Infusion Phlebitis

Phlebitis | Thrombophlebitis

Thailand
Alcon Research

Completed

Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium

Contact Lens Wear

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma

Immune System Diseases | Multiple Myeloma

United States
Masonic Cancer Center, University of Minnesota
BioMarin Pharmaceutical

Terminated

Naglazyme After Allo Transplant for Maroteaux-Lamy Syndrome

Maroteaux-Lamy Syndrome

United States
Becton, Dickinson and Company

Completed

Evaluation of the Antimicrobial Effectiveness of CHG/IPA

Microbial Colonization

Romania
Becton, Dickinson and Company

Completed

Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation

Preoperative Skin Preparation

United States
Hospital de Clinicas de Porto Alegre

Unknown

Paraspinal Stimulation in Treating MPS (DIMMST)

Clinical Study - RCT

Brazil
Queen Mary University of London
Metagenics, Inc.

Unknown

SPM Regulation by Fish Oil Supplements in Healthy Volunteers

Healthy Volunteers

United Kingdom
Phoenix Nest
Aparito Ltd.; Vaincres Les Maladies Lysosomales; Association Sanfilippo Sud

Not yet recruiting

Natural History Study of Participants With Sanfilippo Syndrome Type IIIC (MPSIIIC)

Sanfilippo Syndrome Type C

United States, France
Shire

Completed

A Study of Patients With Sanfilippo Syndrome Type A (MPS IIIA)

Sanfilippo Syndrome Type A

United States
Shire

Completed

Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)

Mucopolysaccharidosis II

United States, United Kingdom, Brazil, Germany
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Sly Disease (MPS VII) (BioSly) (BioSly)

Developmental Delay | Splenomegaly | Hepatomegaly | Skeletal Abnormalities

Germany, India, Sri Lanka, Egypt
Otsuka Pharmaceutical Co., Ltd.

Completed

A Dose-finding Study for SPM 962 in Advanced Parkinson's Disease Patients

Parkinson's Disease

Japan
UCB Pharma

Completed

A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy

Diabetic Neuropathy

Germany
Otsuka Pharmaceutical Co., Ltd.

Completed

A Placebo-controlled Study for SPM 962 in Early Parkinson's Disease Patients

Early Parkinson's Disease

Japan
REGENXBIO Inc.

Enrolling by invitation

Long Term Follow-Up for RGX-111

Mucopolysaccharidosis I

United States, Brazil
Shire

Completed

An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment

Hunter Syndrome

United States, United Kingdom, Canada
Novartis Pharmaceuticals

Completed

Study to Evaluate the Combination of Enteric-coated Mycophenolate Sodium (EC-MPS), Basiliximab, and C2-monitored Cyclosporine in de Novo Renal Transplant Recipients at Potential High Risk of Delayed Graft Function (DGF)

Renal Transplantation
Novartis

Completed

Extension Study of Enteric-coated Mycophenolate Sodium With Short-term or no Steroid Use Compared With Enteric-coated Mycophenolate Sodium With Standard Steroid Therapy in de Novo Kidney Recipients

Renal Transplantation
Novartis

Completed

Extension Study on the Safety and Efficacy of Enteric-coated Mycophenolate Sodium in Kidney Transplant Recipients

Renal Transplantation
Shire

Completed

Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment (AIM-IT)

Hunter Syndrome

Spain, United States, Canada, United Kingdom, France, Australia, Mexico
Abbott Medical Optics

Completed

Evaluation of an Investigational Multi-Purpose Solution (MPS)

Study Focus is Healthy Contact Lens Wearers

United States
Emory University
BioMarin Pharmaceutical

Terminated

Discovering New Biomarkers For Monitoring Disease Progression in Patients With Mucopolysaccharidosis IVA

Mucopolysaccharidosis Type IVA

United States
University Hospital, Basel, Switzerland

Completed

Combined Use of a Novel Cardioplegic Formula With MPS® Versus Cardioplexol ® in Urgent Isolated CABG Using MiECC in Patients With Recent Acute Myocardial Infarction

Heart Attack | Coronary Artery Bypass Grafting (CABG) | Cardioplegia Solution Adverse Reaction

Switzerland
Zhishui Chen

Not yet recruiting

Efficacy and Safety of Enteric-Coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients

Kidney Transplant Rejection
Epstein, Arthur B., OD, FAAO
Alcon Research

Completed

Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses

Keratitis

United States
Allievex Corporation

Enrolling by invitation

Safety, Tolerability and Efficacy of ICV AX 250 Treatment in MPS IIIB -OLE

MPS III B

United States, Germany, Turkey, United Kingdom, Colombia
[Redacted]

Withheld

[Trial of device that is not approved or cleared by the U.S. FDA]
Nestlé

Completed

Daily Protein Intake Distribution and MPS (ARCIII)

Overweight
Ultragenyx Pharmaceutical Inc

Completed

Study of UX003 Recombinant Human Beta-Glucuronidase (rhGUS) Enzyme Replacement Treatment in Mucopolysaccharidosis Type 7, Sly Syndrome (MPS 7) Patients Less Than 5 Years of Age

Mucopolysaccharidosis | Sly Syndrome | Mucopolysaccharidosis VII | MPS VII

Spain, United States, Portugal
Novartis

Completed

Measurement of Patient Reported Gastrointestinal (GI) and Health-related Quality of Life (HRQL) Outcomes in Renal Transplant Recipients (MyLife)

Renal Transplantation | Gastrointestinal Problems

Germany, Switzerland
Brown University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Indiana University

Recruiting

Mobile Peer Support for OUD Recovery (MPS)

Opioid Use Disorder

United States
Alexion Pharmaceuticals

Terminated

Natural History Study to Characterise the Course of Disease Progression in Participants With Mucopolysaccharidosis Type IIIB

MPS IIIB (Sanfilippo B Syndrome)

Spain, United States, Brazil, United Kingdom, Portugal, Italy
Patricia I. Dickson, M.D.
The Ryan Foundation

Terminated

Extension Study of Intrathecal Enzyme Replacement Therapy for MPS I

Mucopolysaccharidosis I | Scheie Syndrome | Lysosomal Storage Disease | Spinal Cord Compression | Hurler-Scheie Syndrome

Finland, United States
LYSOGENE

Active, not recruiting

Study of AAVrh10-h.SGSH Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA) (AAVance)

Mucopolysaccharidosis Type IIIA

Germany, United States, United Kingdom, France, Netherlands
Genzyme, a Sanofi Company
BioMarin/Genzyme LLC

Completed

Clinical Study of Aldurazyme in Patients With Mucopolysaccharidosis (MPS) I

Mucopolysaccharidosis I | Hurler-Scheie Syndrome | Hurlers Syndrome

United States, Canada, Germany

Search clinical trials for: Mucopolysaccharidosis (mps) ii

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