Search clinical trials for: Neoplastic Disease

Total 384369 results

Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Neurofibromatosis 1

United States
Cedars-Sinai Medical Center
Jarrow Formulas Inc

Not yet recruiting

SAMe in Prevention of Oxaliplatin-associated Liver Injury

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Liver Injury | Sinusoidal Obstruction Syndrome | 5-Fluorouracil Toxicity | Liver Toxicity, Chemically-Induced

United States
Copenhagen University Hospital at Herlev

Recruiting

High Impact Training to Patients With Prostate Cancer and Bone Metastases (HIP)

Prostate Cancer

Denmark
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Prospective Validation of Pathology-based Artificial Intelligence Diagnostic Model for Lymph Node Metastasis in Prostate Cancer

Prostatic Neoplasms | Lymphatic Metastasis

China
National Cancer Institute (NCI)

Recruiting

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Gastrointestinal Cancer | Genitourinary Cancer | Metastatic Solid Cancers

United States
Gruppo Oncologico del Nord-Ovest

Recruiting

Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease (TRINITY)

Gastric Cancer | HER2-positive Gastric Cancer

Italy
Brigham and Women's Hospital

Not yet recruiting

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

Pathologic Processes | Lung Cancer | Lymph Node Metastasis
Sunnybrook Health Sciences Centre
MOUNT SINAI HOSPITAL; Princess Margaret Hospital, Canada; Trillium Health Partners

Recruiting

MRI Screening for Brain Metastases Among Patients With Triple Negative or HER2+ Stage II or III Breast Cancer

Breast Cancer

Canada
Guangdong Provincial People's Hospital

Not yet recruiting

The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis

Lung Cancer | Surgery | Autologous Blood Transfusion | Spinal Metastases | Blood Transfusion Complication
Hospices Civils de Lyon

Not yet recruiting

Fertility and Pregnancy After Avelumab Treatment (FERTILAVE)

Immune Checkpoint Inhibitors | Gestational Trophoblastic Tumours

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

AI-Based Multimodal Multi-tasks Analysis Reveals Tumor Molecular Heterogeneity, Predicts Preoperative Lymph Node Metastasis and Prognosis in Papillary Thyroid Carcinoma

Papillary Thyroid Carcinoma; Molecular Heterogeneity; Multi-model Analysis; Artificial Intelligence; Lymph Node Metastases; Disease-free Survival

China
Fudan University

Recruiting

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases

Brain Metastases | SCLC,Extensive Stage

China
Instituto Nacional de Cancerologia de Mexico

Recruiting

Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

Non-small Cell Lung Cancer | Brain Metastases | EGFR Gene Mutation

Mexico
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical Trial

Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis

China
British Columbia Cancer Agency

Not yet recruiting

Diagnostic CT Palliative Radiotherapy: Feasibility Study of Treating Bone Metastases Without a CT Simulation (dCT-PRT)

Bone Metastases
Koç University

Not yet recruiting

Feasibility of SOLAR Group Program Among MHPSS Workers After the Earthquake

Depression | Anxiety | Psychological Distress | Secondary Trauma

Turkey
Personalis Inc.

Recruiting

ctDNA Based MRD Testing for NAC Monitoring in TNBC (B-STRONGER-I)

Minimal Residual Disease | TNBC - Triple-Negative Breast Cancer

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Development and Validation of a PSN-AI Prediction Model (PSN-AI)

Colorectal Cancer | Peritoneal Metastases

China
Ruijin Hospital

Recruiting

a Feasibility Study of iHD-SRT for BM

Brain Metastases, Adult | Stereotactic Radiotherapy

China
First Affiliated Hospital of Chengdu Medical College

Recruiting

Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization

Primary Aldosteronism | Resistant Hypertension | Secondary Hypertension | Secondary Hypertension to Endocrine Disorders

China
Fudan University

Recruiting

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

HER2-negative Breast Cancer | Leptomeningeal Metastasis

China
Gene Solutions

Recruiting

Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.

Breast Cancer | Gastric Cancer | Colorectal Cancer | Non Small Cell Lung Cancer | Advanced Cancer | Liver Cancer | Immune Checkpoint Inhibitor

Vietnam
Alethia Biotherapeutics

Recruiting

Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis (EGIA-003)

Metastatic Colorectal Cancer

Canada
Shanghai JMT-Bio Inc.

Not yet recruiting

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors
National Cancer Institute (NCI)

Not yet recruiting

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

Neurofibromatosis 1 | Nerve Sheath Neoplasms

United States
Tampere University Hospital
Tampere University

Recruiting

Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)

Lynch Syndrome | Urothelial Carcinoma

Canada, Finland
Yana Najjar
Replimune Inc.

Recruiting

RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis

Melanoma

United States
Sichuan University

Not yet recruiting

HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis

Gastric Cancer | Peritoneal Metastases
Fudan University

Not yet recruiting

SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases

Brain Metastasis | TNBC

China
Peking University People's Hospital

Recruiting

Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction

Acute Leukemia | MDS | CML | MDS/MPN

China
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

Brain Metastases | Brain Metastases, Adult | High-grade Glioma

United States
Shengjing Hospital

Recruiting

MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases

Metastatic Colorectal Cancer

China
Radiotherapy Oncology Centre "Santa Maria" Hospital
Paola Anselmo,MD; Michelina Casale,PhD; Fabio Trippa,MD

Recruiting

Stereotactic Ablative Radiotherapy in Synchronous and Metachronous Oligo-Metastatic Non Small Cell Lung Cancer (STARTNEWERA-OM)

NSCLC | Non Small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic | NSCLC Stage IV | Oligometastatic Disease | Non-Small Cell Squamous Lung Cancer | Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor | Non-Small Cell Adenocarcinoma and other conditions

Italy
Oslo University Hospital
University of Oslo; Helse Stavanger HF; Haukeland University Hospital; St. Olavs... and other collaborators

Recruiting

Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases (SYLMET)

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Colorectal Neoplasms Malignant

Norway
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Not yet recruiting

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

Hepatocellular Carcinoma | Liposarcoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Malignant Rhabdoid Tumor | Yolk Sac Tumor | Embryonal Sarcoma of Liver

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Machine Learning Predicts Survival and Mutations in Ovarian Metastases of Colorectal Cancer

Ovarian Metastases of Colorectal Cancer

China
University of Alabama at Birmingham
Children's Hospital of Philadelphia; Congressionally Directed Medical Research...

Not yet recruiting

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1 (NF114)

Neurofibromatosis 1 | Plexiform Neurofibroma
Amsterdam UMC, location VUmc
Angiodynamics, Inc.

Not yet recruiting

COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases (COLDFIRE-III)

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Unresectable Solid Tumor
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co....

Not yet recruiting

A Bridging Study of Liposomal Cytarabine-Daunorubicin in Treating Olderly Patients With Treatment-naive High-Risk (Secondary) Acute Myeloid Leukemia

High-risk (Secondary) Acute Myeloid Leukemia

China
Leiden University Medical Center
Philips Healthcare; European Commission

Recruiting

Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors (A-IMAGIO)

Hepatocellular Carcinoma | Liver Metastases | Liver Cancer | Liver Metastasis Colon Cancer

Netherlands
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia (POYANG)

Choroidal Neovascularization Secondary to Pathologic Myopia

Korea, Republic of, China, Australia, Singapore, Poland, France, Germany, Italy, Taiwan, Hong Kong, Spain
AstraZeneca

Recruiting

Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs (PEDIA)

Neurofibroma, Plexiform

China
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

The Psychological Impact of GTN on Women Who Have Completed Chemotherapy Treatment (PI-GTN)

Gestational Trophoblastic Neoplasia

United Kingdom
Melanoma and Skin Cancer Trials Limited

Not yet recruiting

Bevacizumab and ICIs + hSRT in Symptomatic Melanoma Brain Metastases (BETTER)

Melanoma Brain Metastases
Stony Brook University
The University of Texas Health Science Center at San Antonio

Recruiting

Definitive Radiation for High-Risk Spine Metastases

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Spine Metastases | Metastatic Tumor | Metastatic Tumor of Bone | Metastatic Tumor to the Spine

United States
Royal Marsden NHS Foundation Trust

Recruiting

Inherited Cancer Early Diagnosis (ICED) Study (ICED)

Lynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene Mutation

United Kingdom
David M. Ritter

Recruiting

Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)

Tuberous Sclerosis Complex | Lymphangioleiomyomatosis

United States
Johns Hopkins University
Neurofibromatosis Therapeutic Acceleration Program

Recruiting

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF). (Mirda)

Cutaneous Neurofibroma | NF1 | Monotherapy

United States
University of Wisconsin, Madison
Blue Earth Diagnostics

Recruiting

18F-FLUC-CEST PET/MR in Patients With Brain Mets

Brain Metastasis | Radiation Therapy | Immunotherapy, Active

United States
Qilu Hospital of Shandong University
The Affiliated Hospital of Qingdao University; Shandong Provincial Hospital; Jinan... and other collaborators

Recruiting

Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer

Stage II-III Gastric Cancer

China

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