Search clinical trials for: Nucleoside analogues

Total 454 results

National Cancer Institute (NCI)

Recruiting

Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

Neoplasms | Myelodysplastic Syndromes | Lymphomas

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection

Puerto Rico, United States, Argentina, Brazil, South Africa, Uganda, Zambia, Haiti, Kenya, Malawi, Tanzania, Thailand, Zimbabwe
Medical College of Wisconsin

Recruiting

Genetic Variants and Susceptibility to Diseases of Prematurity in Very Low Birth-Weight Infants (CLD)

Chronic Lung Disease

United States
Mansoura University

Active, not recruiting

Amino Acids Supplementation and Exercise Intervention in Hemodialysis Patients

Malnutrition | Hemodialysis Complication

Egypt
National Institute of Diabetes and Digestive and...

Completed

Withdrawal of Therapy After Long-Term Antiviral Treatment for Chronic Hepatitis B

Chronic Hepatitis B e Antigen Positive | Chronic Hepatitis B e Antigen Negative

United States
National Cancer Institute (NCI)

Suspended

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

Neoplasms | Solid Tumors

United States
Gilead Sciences

Active, not recruiting

Study To Evaluate Emtricitabine/Tenofovir Alafenamide (F/TAF) in Human Immunodeficiency Virus 1 (HIV-1) Infected Children and Adolescents Virologically Suppressed on a 2- Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (2-NRTI)-Containing Regimen

HIV-1

United States, Panama, South Africa
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Completed

Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1

HIV Infections

United States, Puerto Rico
Mayo Clinic

Enrolling by invitation

Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics

Pancreatic Diseases

United States
Imperial College London
Nucana

Completed

NUC-1031 in Patients With Advanced Solid Tumours (ProGem1)

Cancer

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI); SpringWorks Therapeutics, Inc.

Active, not recruiting

A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery

Desmoid Fibromatosis | Recurrent Desmoid Fibromatosis | Unresectable Desmoid Fibromatosis

United States, Canada, Puerto Rico, Australia, New Zealand
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

A Phase IIb Study to Evaluate a Long-Acting Intramuscular Regimen for Maintenance of Virologic Suppression (Following Induction With an Oral Regimen of GSK1265744 and Abacavir/Lamivudine) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected, Antiretroviral Therapy-Naive Adult Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

Germany, Spain, France, United States, Canada
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Active, not recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants

HIV Infections

United States, Germany, Netherlands, Spain, France, Canada, United Kingdom, Italy, South Africa, Russian Federation, Japan
Castagna Antonella
Bristol-Myers Squibb; ViiV Healthcare

Completed

A Study of a Nucleoside Sparing Regimen in HIV-1 Infected Patients With Detectable Viremia (Dolatav)

HIV-1 Infection

Italy
Jagiellonian University
Medical University of Warsaw

Completed

Clinical Application of the Prototype J-PET Device (JPETClinic)

Neurodegenerative Diseases | Brain Neoplasms | Neuroendocrine Tumors

Poland
SCRI Development Innovations, LLC
Ipsen

Terminated

Study of Lanreotide in Patients With Metastatic Gastrointestinal Neuroendocrine Tumors Who Are Undergoing Liver-directed Radioembolization With Yttrium-90 Microspheres

Gastrointestinal Neoplasms | Neuroendocrine Tumors | Carcinoid Tumors

United States
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

Regimen Switch to Dolutegravir + Rilpivirine From Current Antiretroviral Regimen in Human Immunodeficiency Virus Type 1 Infected and Virologically Suppressed Adults (SWORD-1)

HIV Infections

Germany, Taiwan, France, United States, Canada, Belgium, Australia, Netherlands, Spain, United Kingdom, Italy, Argentina, Russian Federation
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

Regimen Switch to Dolutegravir + Rilpivirine From Current Antiretroviral Regimen in Human Immunodeficiency Virus Type 1 Infected and Virologically Suppressed Adults (SWORD-2)

HIV Infections

Germany, Spain, United States, Canada, Taiwan, France, Italy, Argentina, United Kingdom, Russian Federation, Australia
UCB BIOSCIENCES, Inc.
Zogenix, Inc.

Active, not recruiting

An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency (Continuation)

Thymidine Kinase 2 Deficiency

United States, Israel, Spain
ViiV Healthcare

Terminated

A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults (DOMINO)

HIV Infections

Spain, France, United States, Canada, Portugal, Germany, Italy, South Africa, Argentina, Russian Federation, Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Quadrivalent High-Dose Influenza Vaccine and a Moderna COVID-19 Vaccine Administered Either Concomitantly or Singly in Participants 65 Years of Age and Older Previously Vaccinated With a 2-dose Schedule of Moderna COVID-19 Vaccine

Healthy Volunteers | Influenza Immunization

United States
Huahui Health

Active, not recruiting

A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia

Chronic HBV Infection

China
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of a Switch to Doravirine, Tenofovir, Lamivudine (MK-1439A) in Human Immunodeficiency Virus (HIV-1)-Infected Participants Virologically Suppressed on an Anti-retroviral Regimen in Combination With Two Nucleoside Reverse Transcriptase Inhibitors (MK-1439A-024) (DRIVE-SHIFT)

HIV-1 Infection
Alonso Vera Torres

Withdrawn

Cri Analog PG1 Effectiveness and Safety in Covid-19 (PGE1-COVID19)

Covid19
Changhai Hospital

Completed

Effects of T-bet B Cells in Persistent Virus Control After Discontinuance of NAs in CHB Patients

Chronic HBV Infection | Drug Withdrawal

China
ANRS, Emerging Infectious Diseases
ViiV Healthcare

Completed

Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing Dolutegravir and Associated Nucleoside / Nucleotide Reverse Transcriptase Inhibitors Backbone (DOLUVOIR)

HIV-1 Infection

France
Kirby Institute

Active, not recruiting

Body Composition Sub-study of the D2EFT Trial

HIV Infections

Malaysia, Zimbabwe, India, South Africa, Thailand
Radboud University Medical Center
University Medical Center Groningen; Catharina Ziekenhuis Eindhoven; St. Antonius... and other collaborators

Completed

Efficacy of Octreotide on Blood and Iron Requirements in Patients With Anemia Due to Angiodysplasias (OCEAN)

Anemia | Vascular Malformations | Gastrointestinal Hemorrhage | Angiodysplasia

Netherlands
The University of Hong Kong

Active, not recruiting

Stopping Antiviral Treatment in Chronic Hepatitis B

Chronic Hepatitis b

Hong Kong
Assembly Biosciences

Terminated

A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients

Chronic Hepatitis B

United States, Canada, Hong Kong, New Zealand, United Kingdom
Johns Hopkins University

Terminated

Glycemia in Diabetic Elders Trial

Type 2 Diabetes Mellitus

United States
Kirby Institute
National Health and Medical Research Council, Australia; National Institute... and other collaborators

Active, not recruiting

Dolutegravir and Darunavir Evaluation in Adults Failing Therapy (D²EFT)

HIV Infections

Mexico, Thailand, Malaysia, Argentina, Brazil, India, Nigeria, South Africa, Chile, Colombia, Guinea, Indonesia, Mali, Zimbabwe
Elizabeth Glaser Pediatric AIDS Foundation
Janssen, LP

Active, not recruiting

Characteristics and Outcomes of Patients Who Received Etravirine and/or Darunavir (NewHorizon)

HIV/AIDS

Cameroon, Kenya, Lesotho, Swaziland, Uganda
Northwell Health
Cohen Children's Medical Center

Available

A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma

Neuroblastoma | Pheochromocytoma

United States
E-DA Hospital

Active, not recruiting

Finite Versus Continuous Nucleos(t)Ide Analogues for Chronic Hepatitis B

Chronic Hepatitis b

Taiwan
Oslo University Hospital
Karolinska University Hospital; Hvidovre University Hospital; Addis Ababa University and other collaborators

Completed

The Norwegian Nucleoside Analogue Stop Study (Nuc-Stop)

Hepatitis B, Chronic

Norway, Denmark, Ethiopia, Sweden
General Hospital of Shenyang Military Region

Completed

Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis

Liver Cirrhosis | Hemorrhage | Venous Thrombosis | Varicose Veins | Portal Vein

China
Universitaire Ziekenhuizen KU Leuven
Ipsen

Completed

SOMATULINE Autogel 90 mg IN DUMPING SYNDROME

Dumping Syndrome

Belgium
University Hospital, Ghent
Pfizer

Completed

Growth Hormone, IGF-1 and Medical Treatment in Acromegaly: Are There Effects on Gut Hormone Physiology and Postprandial Substrate Metabolism?

Acromegaly

Belgium
Xennials Therapeutics Australia Pty Ltd
Pinotbio, Inc.

Terminated

NTX-301 Monotherapy in Advanced Solid Tumours and in Combination With Platinum-based Chemotherapy in Advanced Ovarian & Bladder Cancer and in Combination With Temozolomide in High-grade Glioma

Advanced Solid Tumor | High-grade Glioma | Platinum-Resistant Ovarian Cancer | Platinum-Resistant Urothelial Carcinoma

Australia
Beijing Friendship Hospital

Active, not recruiting

Carvedilol for Prevention of Esophageal Varices Progression (Carvedilol)

Portal Hypertension | Cirrhosis, Liver

China
Sanofi

Completed

Comparison of Glucose Values and Variability Between TOUJEO and TRESIBA During Continuous Glucose Monitoring in Type 1 Diabetes Patients (inRange)

Type 1 Diabetes Mellitus

Turkey, Netherlands, Brazil, United States, Germany, Hungary, United Kingdom
Clinica de la Mujer Medicina Reproductiva, Chile

Completed

DYG Versus Cetrorelix in Oocyte Donation

Infertility, Female | Fertility Disorders
Montefiore Medical Center

Active, not recruiting

Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer

Prostatic Neoplasms

United States
HIV Prevention Trials Network

Completed

The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP) (ADAPT)

HIV Infections

United States, South Africa, Thailand
University Hospital, Basel, Switzerland

Completed

Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues (SKIP)

Smoking Cessation | Craving | Weight Change, Body | Glucagon-like Peptide-1

Switzerland
University Hospital, Basel, Switzerland
Swiss National Science Foundation; Goldschmidt-Jacobson Foundation

Completed

Effects of Glucagon-Like Peptide-1 Analogs on Sexuality (DESIRE)

Sexual Functioning

Switzerland
M.D. Anderson Cancer Center

Completed

Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8

United States
Lai Wei

Active, not recruiting

Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis B

To Evaluate the Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues in Nucleos(t)Ide-treated Patients With Chronic Hepatitis B

China
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome

Idiopathic Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

United Kingdom

Search clinical trials for: Nucleoside analogues

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