Search clinical trials for: Open Label Study

Total 124681 results

Novartis Pharmaceuticals

Recruiting

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC. (PSMA-DC)

Oligometastatic Prostate Cancer (OMPC)

Japan, Singapore, Canada, Israel, Switzerland, Australia, United States
Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
University of Milano Bicocca

Not yet recruiting

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

Malignancies | Glioblastoma, IDH-wildtype | Metformin

Italy
Flare Therapeutics Inc.

Recruiting

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Advanced Solid Tumors Cancer | Advanced Urothelial Carcinoma | Open Label | Oral Drug Administration

United States
AstraZeneca

Recruiting

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) (DAISY)

Systemic Sclerosis | Scleroderma

United States, Italy, Mexico, Hungary, Belgium, Spain, Japan, Poland, Germany, China, India, Korea, Republic of, Vietnam, France, Austria, Israel, Canada, Turkey, Netherlands, United Kingdom, South Africa, Romania
Mayo Clinic

Recruiting

A Study of FRaDCs for Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube Carcinosarcoma | Primary Peritoneal Carcinosarcoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian... and other conditions

United States
University of Derby
University of Exeter; University Hospitals of Derby and Burton NHS Foundation... and other collaborators

Not yet recruiting

An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. (ERASE-LC)

COVID-19 | SARS-CoV-2 Infection

United Kingdom
National Institute of Allergy and Infectious Diseases...

Recruiting

Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults

Malaria

United States
Servier Affaires Médicales

Recruiting

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

Acute Myeloid Leukemia (AML)

Netherlands, Italy, Austria, France
National Taiwan University Hospital

Not yet recruiting

Efficacy of Lenalidomide Maintenance in Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma: a Phase II, Open-label, Single-arm Study

Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma
Novartis Pharmaceuticals

Recruiting

An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinemia (a)

Germany
Erasmus Medical Center

Recruiting

TEIPP Immunotherapy in Patients With NSCLC (TEIPP)

Non Small Cell Lung Cancer

Netherlands
Inhibrx, Inc.

Not yet recruiting

Open Label Extension Study of INBRX-101 in Adults With AATD Emphysema (ELEVAATE OLE)

Emphysema | Alpha 1-Antitrypsin Deficiency
Centre Francois Baclesse
National Cancer Institute, France

Not yet recruiting

Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous Sinus Meningioma: An Open-label Randomized 1:1 Phase III Study (COG-PROTON-01)

Cognitive Impairment | Cavernous Sinus Meningioma | Proton-therapy | Photon Radiotherapy

France
Advanced Integrative Medical Science Institute

Not yet recruiting

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

Major Depression | Post Traumatic Stress Disorder

United States
Yonsei University

Not yet recruiting

An Open Label, Single-arm, Multicenter Phase Ib/II Study to Evaluate the Safety and Efficacy of T-Dxd in Combination With Ramucirumab as a 2nd Line in Patients With HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer | Gastroesophageal Junction (GEJ) Cancer
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

An Open-label Phase 3 Study of Lutetium (177Lu) Oxodotreotide Injection in Subjects With Advanced Gastrointestinal Pancreatic Neuroendocrine Tumors.

Advanced Gastroenteropancreatic Neuroendocrine Tumor

China
River 2 Renal Corp.

Recruiting

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

Acute Kidney Injury | Hepatorenal Syndrome

United States
Akeso

Recruiting

A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
Ichnos Sciences SA

Recruiting

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States, Australia
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Ovarian Epithelial Carcinoma

Ovarian Epithelial Carcinoma
PRG Science & Technology Co., Ltd.

Not yet recruiting

Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin in Werner Syndrome

Werner Syndrome
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Healthy Subjects

United States
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma
Central South University

Recruiting

Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders

Bipolar Disorder | Major Depressive Disorder

China
Pfizer

Recruiting

A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway. (DELINOR)

Non-Small Cell Lung Cancer

Norway
APR Applied Pharma Research s.a.

Recruiting

Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.

Phenylketonurias

Italy
Magnus Medical

Recruiting

Open Label Optimization Study (OLO)

Major Depressive Disorder

United States
Novartis Pharmaceuticals

Recruiting

An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

Spain, Switzerland, Germany, Australia, France, United States
Quoin Pharmaceuticals

Recruiting

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome

United States
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
Sanofi

Recruiting

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis (ATLANTIS)

Dermatitis Atopic

Italy, United Kingdom, Argentina, France, Chile, Czechia, Germany, Japan, Spain, China, Netherlands, Brazil, Canada, Denmark, Korea, Republic of, South Africa, Taiwan, Poland, India, Mexico
University Hospital, Bordeaux

Not yet recruiting

Outpatient Holmium LASER Enucleation of the Prostate: Benefit of MOSES(TM) 2.0 Technology (MOSES)

Benign Prostatic Hypertrophy | Holmium Laser Enucleation of the Prostate
1ST Biotherapeutics, Inc.
Merck Sharp & Dohme LLC

Recruiting

A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849

Advanced Solid Tumor

United States
Alpine Immune Sciences, Inc.

Recruiting

An Open-label Study of Povetacicept in Subjects With Autoimmune Cytopenias (RUBY-4)

Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura | Cold Agglutinin Disease | Warm Autoimmune Hemolytic Anemia

United States, Canada, Australia, Turkey, United Kingdom
Calico Life Sciences LLC
AbbVie

Recruiting

An Open-Label Exploratory Study of ABBV-CLS-7262 Subjects With Vanishing White Matter Disease

Vanishing White Matter Disease

United States, Netherlands
Humanitas Mirasole SpA
KU Leuven; UMC Utrecht; University of Sheffield; Istituto Superiore di Sanità; University... and other collaborators

Recruiting

Open Label Extension of TUDCA-ALS Study (TUDCA-ALS OLE)

Amyotrophic Lateral Sclerosis

Germany, France, Netherlands, Italy, United Kingdom, Belgium, Ireland
Hefei TG ImmunoPharma Co., Ltd.

Recruiting

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

Melanoma | Colorectal Cancer | Ovarian Cancer | Triple Negative Breast Cancer

United States
Incyclix Bio

Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer (INX-315-01)

Breast Cancer | Ovarian Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Breast Cancer Metastatic | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | CCNE1 Amplification

United States, Australia
Alpine Immune Sciences, Inc.

Recruiting

An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney Diseases (RUBY-3)

Lupus Nephritis | Immunoglobulin A Nephropathy | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Membranous Nephropathy

United States, Australia, Korea, Republic of, Austria, Norway, Spain, United Kingdom
Palatin Technologies, Inc

Recruiting

A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease (BREAKOUT)

Kidney Disease

United States
SURGE Therapeutics

Recruiting

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

Non-muscle-invasive Bladder Cancer

United States
AstraZeneca

Recruiting

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations (AVANZAR)

NSCLC

China, United States, United Kingdom, Korea, Republic of, Italy, Hungary, Spain, Vietnam, France, Brazil, Canada, Japan, Taiwan, Germany, Austria, Turkey, India, Peru, Poland, Sweden, Bulgaria, Greece, Mexico, Denmark
First Affiliated Hospital of Shantou University...
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Advanced Triple Negative Breast Cancer

Advanced Triple Negative Breast Cancer

China
M.D. Anderson Cancer Center
Daiichi Sankyo

Recruiting

A Phase 1/2, Open-label Study of Valemetostat in Combination With Rituximab and Lenalidomide in Relapsed or Refractory Follicular Lymphoma

Lymphoma

United States
Beckley Psytech Limited

Recruiting

An Open-Label, Single Dose Study in Patients With Alcohol Use Disorder

Alcohol Use Disorder

United Kingdom
M.D. Anderson Cancer Center
Tvardi Therapeutics, Inc

Not yet recruiting

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Squamous Cell Carcinoma
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

A Multicenter Open-label Clinical Study on the Prevention of Premature Ovarian Failure After HSCT

Hematopoietic Stem Cell Transplantation | Premature Ovarian Failure

China
GC Biopharma Corp

Not yet recruiting

An Open-label, Bridging Study of BARYCELA Inj. in Healthy Vietnamese Children Aged Between 12 Months to 12 Years

Varicella Zoster Virus Infection
Beckley Psytech Limited

Recruiting

An Open-Label, Single Dose Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression

Treatment Resistant Depression

United Kingdom

Search clinical trials for: Open Label Study

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mexico

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations