Search clinical trials for: Peptic ulcer rebleeding, double dose of esomeprazole

Total 432904 results

Eisai Inc.

Completed

Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

Chile, Canada, United States, Estonia, India, Hungary, Bulgaria, Croatia, Australia, Lithuania, Latvia, Argentina, France, Germany
Kaohsiung Veterans General Hospital.
Baylor College of Medicine

Completed

Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection (960025)

Helicobacter Infection

Taiwan
Kaohsiung Veterans General Hospital.

Completed

Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcer

Peptic Ulcer

Taiwan
Xijing Hospital of Digestive Diseases

Completed

Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis | Dyspepsia | Peptic Ulcer

China
AstraZeneca

Completed

Compare D961H 20 mg Bid and 20 mg qd in Patients With Refractory Reflux Esophagitis (Inflammation of Lower Esophagus)

Refractory Reflux Esophagitis

Japan
Chinese University of Hong Kong

Completed

Effect of IV and Oral Esomeprazole in Prevention of Recurrent Bleeding From Peptic Ulcers After Endoscopic Therapy (IOE)

Bleeding | Peptic Ulcer

China
Eurofarma Laboratorios S.A.

Withdrawn

Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC

Gastroesophageal Reflux Disease

Brazil
isRed Pharma & Biotech Research Corporation
Yung Shin Pharmaceutical Ind. Co., Ltd.

Unknown

A Pharmacokinetic Study to Evaluate the Bioequivalence of a Test Formulation Compared to an Equivalent Dose of a Reference Drug Product

Healthy Adult Subjects

Taiwan
Lotung Poh-Ai Hospital
Tomorrow Medical Foundation

Withdrawn

Esomeprazole Versus Pantoprazole to Prevent Peptic Ulcer Rebleeding

Peptic Ulcer
Fudan University
Istituto Superiore di Sanità

Completed

Docetaxel and Cisplatin Chemotherapy With or Without High Dose Proton Pump Inhibitor in Metastatic Breast Cancer

Breast Cancer | Metastasis, Neoplasm

China
AstraZeneca

Completed

Local Phase IV, Gastroesophageal Reflux Disease (GERD) Sleep Study US

Gastroesophageal Reflux Disease

United States
Eisai Co., Ltd.

Completed

Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)

Gastric or Duodenal Ulcers Caused by Low-dose Aspirin

Japan
Boehringer Ingelheim

Completed

Influence of Pantoprazole on the Pharmacokinetics of Fradafiban After Multiple Oral Doses of Lefradafiban in Healthy Subjects

Healthy
Boehringer Ingelheim

Completed

Influence of Pantoprazole on the Pharmacokinetics of Fradafiban After Multiple Oral Doses of Lefradafiban Over 5 Days in Healthy Subjects

Healthy
US Department of Veterans Affairs

Completed

Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPI

Gastroesophageal Reflux Disease

United States
AstraZeneca

Completed

Risk of Uncomplicated Peptic Ulcer in the General Population

Peptic Ulcer [Iowa Type (107680.0010)]

Spain
Yuhan Corporation

Completed

Study to Investigate the Safety, Tolerability and Efficacy of YH4808 in Patients With Reflux Esophagitis

Reflux Esophagitis

Korea, Republic of
Yuhan Corporation

Completed

Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Ocera Therapeutics

Terminated

Safety and Efficacy of AST-120 in Patients With GERD Who Continue to be Symptomatic on a Standard Dose of PPI

Gastroesophageal Reflux Disease (GERD)

United States
Mansoura University

Completed

Single Versus Double Dose Intra-vaginal Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy

Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy
AstraZeneca

Completed

Phase 3/Safety & Efficacy of Esomeprazole in Infants

Gastroesophageal Reflux Disease (GERD)

United States, France, Poland, Germany
Takeda
Richmond Pharmacology Limited

Completed

Safety, Tolerability, and Pharmacokinetics of TAK-438 in Healthy Western Male Subjects, Preliminary Food Effect Analysis, and an Ethnic Comparison With Japanese Subjects

Dose Finding Study
Asbjørn Mohr Drewes

Completed

A Study of Local Effect and Safety of a Single PPC-5650 Dose on Reflux Pain During Pain Stimulation in the Esophagus

Gastroesophageal Reflux | Gastroesophageal Reflux Disease

Denmark
Takeda

Completed

Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin

Gastric Ulcers | Duodenal Ulcers

Japan
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

Healthy Subjects | Pharmacokinetics of Isavuconazole

United States
Janssen-Cilag Pty Ltd

Completed

A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg

Gastro-oesophageal Reflux

Australia
Takeda

Completed

A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Low-Dose Aspirin Therapy

Gastric Ulcer | Duodenal Ulcer

Japan
Takeda

Completed

Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin

Gastric Ulcers | Duodenal Ulcers

Japan
Hospital Authority, Hong Kong
The University of Hong Kong

Completed

Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients

Gastroesophageal Reflux | Laryngitis

China
Janssen Research & Development, LLC
Eisai Inc.

Completed

A Study of Single and Multiple Doses of Rabeprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Months Old, Inclusive

Gastroesophageal Reflux Disease (GERD)

United States, Poland, United Kingdom, Belgium, Brazil
HK inno.N Corporation

Completed

Safety, Tolerability, PK, PD of Escalating Single and Multiple Oral Doses of CJ-12420 in Healthy Male Subjects

Healthy

Korea, Republic of
China Medical University Hospital

Unknown

Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

Taiwan
AstraZeneca
Parexel

Completed

To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole

Gastroesophageal Reflux Disease | GERD | Reflux Esophagitis
AstraZeneca

Completed

Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer

Osteoarthritis | Rheumatoid Arthritis | Lumbago | Gastric Ulcer | Duodenal Ulcer

Japan
Chinese University of Hong Kong

Terminated

A Comparison of Gastric pH Control With High Dose Intravenous or Oral Esomeprazole

Gastrointestinal Hemorrhage

China
AstraZeneca

Completed

Esomeprazole (NEXIUM) vs. Surgery (LOTUS)

Gastroesophageal Reflux

Italy, Sweden, Germany, Denmark, Finland, Norway, Netherlands, Austria, Belgium, United Kingdom, France, Iceland
Vecta Ltd.

Completed

Active Control, Double-blind, Double-dummy, Parallel-group, Randomized Study to Assess the Effect of VECAM 40/300, Administered at Bedtime, vs. Esomeprazole 20 mg, Administered 30-60 Min. Before Dinner, on Daytime and Nighttime GERD Symptoms

Gastroesophageal Reflux

United States
Ascopharm Groupe Novasco
Groupe Hospitalier Pitie-Salpetriere; Medco Health Solutions, Inc.

Completed

Double the Dose of Clopidogrel or Switch to Prasugrel to Antagonize Proton Pump Inhibitor Interaction. (DOSAPI)

Anti Platelet Effects

France
AstraZeneca

Completed

Assessment of Pharmacokinetics of a Single Oral Dose of VIMOVO in Healthy Adult Volunteers

Juvenile Idiopathic Arthritis

United States
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Takeda

Completed

Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506)

Gastroesophageal Reflux | GERD | GORD

United Kingdom
Eisai Co., Ltd.

Completed

Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux Esophagitis

Refractory Reflux Esophagitis

Japan
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
AstraZeneca

Terminated

Study Comparing Esomeprazole and ASA Combined Together as One Capsule Versus These Medications Taken Separately

Peptic Ulcer Disease

Canada
Otsuka Pharmaceutical, Inc., Philippines

Completed

Randomized Double-Blind Clinical Trial of Rebamipide vs Esomeprazole in the Treatment of NSAID-induced Gastropathy

NSAID Induced Gastropathy

Philippines
Taiho Pharmaceutical Co., Ltd.
UCB Pharma

Completed

Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine -

Gastroesophageal Reflux

Japan
AstraZeneca

Completed

A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer

Gastrointestinal Hemorrhage

Sweden, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Romania, Finland, Norway, Hong Kong, Austria, Denmark, Netherlands, Greece, France
AstraZeneca

Completed

A Study to Estimate Effect of 4 Different Doses of AZD3355 on Reflux Episodes, Which Patients With Gastroesophageal Reflux Disease (GERD) May Experience

Gastroesophageal Reflux Disease

United States

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