Search clinical trials for: Potential drug-drug interaction

Total 4908 results

GlaxoSmithKline

Completed

The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in Subjects

Nausea and Vomiting, Chemotherapy-Induced

United States
GlaxoSmithKline

Completed

To Estimate the Potential Effects of Repeat Doses of Darapladib on the Pharmacokinetics (PK) of Rosuvastatin as Well as Evaluating Safety and Tolerability in Healthy Volunteers

Atherosclerosis

United States
GlaxoSmithKline

Completed

GSK239512 DDI Study

Multiple Sclerosis

Australia
Bayer

Completed

Drug-drug Interaction Study Between Orally Administered Rifampicin and Vilaprisan

Endometriosis

Germany
GlaxoSmithKline

Terminated

GSK2647544 RD, DDI in Healthy Young and Elderly Volunteers

Alzheimer's Disease

United Kingdom
University Hospital, Clermont-Ferrand
Neuromed IRCCS; Centre de Recherche en Nutrition Humaine d'Auvergne; Mediterranean...

Unknown

Diet Interactions With Human Gut Microbiota. The Potential Role of Mediterranean Diet Adherence. DIAGRAM, a Pilot Study (DIAGRAM)

Human Gut Microbiota

France
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
F2G Biotech GmbH
Celerion Ltd

Completed

Study of Potential for Interaction of Fluconazole With F901318

Invasive Aspergillosis

United Kingdom
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1

Cocaine-Related Disorders

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Safety Assessment of Potential Interactions Between IV Methamphetamine and Osmotic-Release Methylphenidate (OROS-MPH)

Methamphetamine Dependence | Methamphetamine Abuse

United States, Canada
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between Cocaine and Tolcapone - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1

Amphetamine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between GBR 12909 and Cocaine - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin

Cocaine Abuse

United States
National Institute on Drug Abuse (NIDA)
University of California, Los Angeles

Unknown

Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1

Amphetamine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1

Cocaine-Related Disorders

United States
Hoffmann-La Roche

Completed

A Study of Potential Drug-Drug Interaction Between Efavirenz and Danoprevir With Low Dose Ritonavir in Healthy Volunteers

Healthy Volunteer

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects

Type 2 Diabetes Mellitus

United States
Actelion

Completed

Potential Pharmacokinetic Interaction Between Selexipag and Midazolam in Healthy Male Subjects

Healthy Subjects

France
Johnson & Johnson Pharmaceutical Research & Development...

Withdrawn

A Study to Evaluate the Pharmacokinetic Drug Interaction Between Multiple Doses of JNJ-31001074 and a Single Dose of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Women

Healthy | Pharmacokinetics | Drug Interactions
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Drug -Drug Interaction of SP2086 and Glyburide

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Drug-drug Interaction of SP2086 and Simvastatin

Type 2 Diabetes

China
Boehringer Ingelheim

Completed

Investigation of Potential Drug-drug Interactions Between Faldaprevir and the Immunosuppressant Drugs Cyclosporine or Tacrolimus

Healthy

Germany
Eisai Inc.

Completed

A 2-Part Study to Assess Potential Metabolism-Based Drug-Drug Interactions of E2006 When Coadministered With Itraconazole, Rifampin, Midazolam, or Bupropion

Healthy Subjects

United States
Pfizer

Completed

Drug Interaction Study To Investigate The Potential Effect Of Proton Pump Inhibitor On The Pharmacokinetics Of Palbociclib (PD-0332991)

Healthy

United States
Pfizer

Completed

A Study To Determine If Coadministration Of Tamoxifen Alters The Extent Or Rate Of Palbociclib (PD-0332991) Absorption Or Elimination In Healthy Male Volunteers

Healthy

United States
Pfizer

Completed

A Drug-Drug Interaction Study To Investigate The Potential For Multiple Doses Of Palbociclib (PD-0332991) To Alter The Pharmacokinetics Of Oral Midazolam In Adult Healthy Women of Non-Childbearing Potential.

Healthy

United States
Vantia Ltd

Completed

Study in Healthy Male Subjects to Evaluate the Effect of Itraconazole and Rifampicin on the PK of Fedovapagon

Nocturia

Germany
University of Zurich

Completed

Vestibular Pain Interactions (VPI)

Healthy

Switzerland
Genzyme, a Sanofi Company

Completed

A Study to Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy Volunteers

Healthy

Netherlands
Leumit Health Services

Completed

Clinical and Economic Impact of an Electronic Medical Record Interfaced Decision Support System Reinforced With Patient Specific Pharmacogenetic Data for Minimizing Severe Drug-Drug Interactions (DDI+)

Healthcare

Israel
Leumit Health Services

Completed

Clinical and Economic Impact of an Electronic Medical Record Interfaced Decision Support System for Minimizing Severe Drug-Drug Interactions (DDI+)

Healthcare

Israel
Boehringer Ingelheim

Terminated

Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine, Abacavir and Amprenavir in HIV-1 Infected Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Naive Adults

HIV Infections
Boehringer Ingelheim

Completed

Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine (VIRAMUNE) and Ethinyl Estradiol/Norethindrone in HIV-1 Infected Women

HIV Infections
Bayer
GlaxoSmithKline; Merck Sharp & Dohme LLC

Completed

Vardenafil ODT (Orally Disintegrating Tablet) - Nifedipine Interaction Study

Erectile Dysfunction

United States
Ventrus Biosciences, Inc
TKL Research, Inc.

Completed

Study to Evaluate the Interaction Potential of Clarithromycin XL on Diltiazem Hydrochloride Cream 2% in Healthy Subjects

CLARITHROMYCIN/DILTIAZEM [VA Drug Interaction]

United States
Tibotec BVBA

Completed

TMC207-TiDP13-C117: Interaction Study in Human Immunodeficiency Virus-type 1 (HIV-1) Infected Patients With Nevirapine (NVP)

HIV Infections

South Africa
Janssen Infectious Diseases BVBA

Completed

A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and Telaprevir

Healthy Participants

Netherlands
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Investigate the Potential Pharmacokinetic Interaction Between TMC435 and Methadone

Hepatitis C

Canada
Boehringer Ingelheim

Completed

Investigation of Pharmacodynamic Effects of Dabigatran and Ticagrelor and Assessment of Ticagrelor Interaction Potential With Dabigatran

Healthy

Germany
University of Colorado, Denver

Completed

Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers

Hepatitis C | HIV

United States
Eisai Inc.

Completed

A Study to Investigate the Potential Pharmacokinetic Interaction of Perampanel With Oral Contraceptives in Healthy Female Subjects

Partial Onset Epilepsy

United Kingdom
The University Clinic of Pulmonary and Allergic...

Unknown

The Role of Clinical Pharmacist in Management of DDIs in CHF Patients

Chronic Heart Failure

Slovenia
HanAll BioPharma Co., Ltd.

Completed

A Study to Evaluate Pharmacokinetics and Potential Drug Interactions of a Fixed-dose Combination Tablet, HL-040XC, in Healthy Male Subjects

Hypertension | Hyperlipidemia

United States
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in Healthy Subjects

Rheumatoid Arthritis | Healthy Subjects

United Kingdom
Tibotec BVBA
Vertex Pharmaceuticals Incorporated

Completed

A Study to Investigate the Potential Interaction Between Telaprevir and Methadone, at Steady-State

Healthy Participants
Pfizer

Completed

Study To Investigate The Potential Drug Drug Interaction (DDI) Between PF-00299804 And Paroxetine In Healthy Subjects

Healthy Volunteers

United States
GlaxoSmithKline

Completed

A Study Investigating Blood Concentrations Of Rosuvastatin When Co-administered With GW856553 In Healthy Men

Cardiovascular Disease | Atherosclerosis

United States
NEMA Research, Inc.

Completed

Exposure to Potential Cytochrome P450 Pharmacokinetic Drug-Drug Interactions Among Osteoarthritis Patients: Incremental Risk of Multiple Prescriptions

Chronic Low Back Pain

3

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