Search clinical trials for: RAS or RAF oncogenes, Inhibition of MEK pathway, inhibition cancer cell proliferation promising anti
Total 465798 results
-
Merck Sharp & Dohme LLCGOG Foundation; European Network of Gynaecological Oncological Trial Groups...Active, not recruitingUterine Cervical NeoplasmsCanada, United States, Australia, Austria, Belgium, Brazil, Chile, China, Colombia, Czechia, France, Germany, Greece, Guatemala, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic of, Norway, Peru, Russian Federation, Spain, Sweden, ... and more
-
National Cancer Institute (NCI)Active, not recruitingLeiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditionsUnited States, Canada, Puerto Rico
-
Merck Sharp & Dohme LLCAstellas Pharma Inc; Seagen Inc.Active, not recruitingBladder CancerHungary, United States, China, Argentina, Australia, Bulgaria, Canada, Colombia, Croatia, Czechia, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Malaysia, Philippines, Poland, Portugal, Romania, Russian Federation, Singapo... and more
-
Incyte CorporationAstraZenecaActive, not recruitingLung CancerUnited States, Korea, Republic of, Spain, Taiwan
-
New Mexico Cancer Care AllianceActive, not recruitingOvarian Cancer | Fallopian Tube Cancer | Peritoneal CancerUnited States
-
New Mexico Cancer Care AllianceActive, not recruitingPeritoneal Neoplasms | Ovarian Cancer | Fallopian Tube CancerUnited States
-
University of California, San FranciscoNovartis Pharmaceuticals; Pacific Pediatric Neuro-Oncology Consortium; The Pediatric...Active, not recruitingPediatric Recurrent Progressive Low-grade Gliomas | Pediatric Progressive Low-grade GliomasUnited States
-
Janssen Research & Development, LLCTerminatedMultiple MyelomaCanada, United States, Belgium, Poland, Italy, France, Spain, Brazil, Russian Federation, Denmark, Greece, Germany, Netherlands
-
Eastern Cooperative Oncology GroupNational Cancer Institute (NCI)Active, not recruitingLymphoma | Neurotoxicity | Therapy-related ToxicityUnited States, Canada
-
Merck Sharp & Dohme LLCGynecologic Oncology Group; European Network for Gynaecological Oncological...Active, not recruitingEndometrial NeoplasmsUnited States, Argentina, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Finland, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Mexico, Norway, Poland, Russian Federation, Spain, Sweden, Taiwan, T... and more
-
AstraZenecaMerck Sharp & Dohme LLCCompletedMetastatic Castration-resistant Prostate CancerBelgium, France, Italy, Netherlands, Poland, United States, Canada, Czechia, Russian Federation, United Kingdom, Spain
-
NYU Langone HealthMerck Sharp & Dohme LLCActive, not recruitingMuscle-invasive Urothelial Cancer of the BladderUnited States
-
BeiGeneActive, not recruitingChronic Lymphocytic Leukemia | Small Lymphocytic LymphomaUnited States, China, Taiwan, Belgium, France, United Kingdom, Spain, New Zealand, Australia, Czechia, Italy, Poland, Russian Federation, Sweden, Austria
-
National Cancer Institute (NCI)NRG OncologyActive, not recruitingRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Seromucinous Carcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian... and other conditionsUnited States, Puerto Rico
-
TakedaActive, not recruitingPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)United States, China, Spain, Australia, Canada, Argentina, Korea, Republic of, Brazil, Japan, Italy, Mexico, France, Greece, Poland, Russian Federation, Austria, Taiwan, Bulgaria, Finland, Turkey
-
Eisai Inc.Merck Sharp & Dohme LLCActive, not recruitingEndometrial NeoplasmsFrance, Canada, United States, Spain, United Kingdom, Italy, Taiwan, Korea, Republic of, Colombia, Australia, New Zealand, Brazil, Turkey, Poland, Israel, Argentina, Germany, Ireland, Japan, Mexico, Russian Federation
-
Basilea PharmaceuticaCompletedUrothelial CarcinomaUnited Kingdom, Korea, Republic of, Italy, Canada, France, Spain, Germany, United States, Hungary, Australia, Poland, Switzerland, Czechia, Austria
-
University of NebraskaNational Cancer Institute (NCI)Completed
-
Universitaire Ziekenhuizen KU LeuvenEuropean CommissionCompletedOvarian Cancer | Fallopian Tube Cancer | Primary Peritoneal CarcinomaGermany, Belgium, Italy, Austria, France
-
Jonsson Comprehensive Cancer CenterGlaxoSmithKline; Novartis; Astellas Pharma Inc; Prostate Cancer Foundation; Medivation...Active, not recruitingProstate CancerUnited States
-
Children's National Research InstituteBristol-Myers SquibbActive, not recruitingMelanoma | Hepatocellular Carcinoma | Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Relapsed Pediatric Solid Tumor | Refractory Pediatric Solid TumorUnited States
-
Hoffmann-La RocheTerminatedRenal Cell CarcinomaKorea, Republic of, United States, Canada, United Kingdom, Argentina, Australia, Belgium, Brazil, China, Denmark, Ireland, Spain, Japan, Netherlands, Chile, Czechia, Italy, France, Israel, Turkey, Germany, Austria, Taiwan, Serbia, Poland, Thailan... and more
-
University of Michigan Rogel Cancer CenterActive, not recruitingProstate CancerUnited States
-
SWOG Cancer Research NetworkNational Cancer Institute (NCI)CompletedRecurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7United States
-
zr Pharma & GmbHFoundation MedicineTerminatedBladder Cancer | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Muscle Invasive Bladder Cancer | Ureter Carcinoma | Renal Pelvis Carcinoma | Urinary Bladder Carcinoma | Urethra CarcinomaUnited States, Spain, France, Italy, Germany, United Kingdom
-
SWOG Cancer Research NetworkNational Cancer Institute (NCI)CompletedRecurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7United States, Canada
-
SWOG Cancer Research NetworkNational Cancer Institute (NCI)CompletedRecurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7United States
-
University of Texas Southwestern Medical CenterCompletedBreast Cancer | Ovarian CancerUnited States
-
Hoffmann-La RocheCompletedRenal Cell CarcinomaKorea, Republic of, United States, France, Italy, United Kingdom, Canada, Australia, Brazil, Denmark, Spain, Turkey, Japan, Czechia, Singapore, Thailand, Taiwan, Russian Federation, Germany, Bosnia and Herzegovina, Poland, Mexico
-
GOG FoundationNational Cancer Institute (NCI)CompletedCervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Stage IIA Cervical Cancer AJCC v7 | Stage IIB Cervical Cancer AJCC v6 and v7 | Stage IIIB Cervical Cancer AJCC v6 and v7 | Stage IVA Cervical Cancer AJCC v6 and v7 | Stage IB Cervical...United States, Canada, Saudi Arabia, China, Singapore
-
Genocea Biosciences, Inc.TerminatedMelanoma | Renal Cell Carcinoma | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Anal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell CarcinomaUnited States
-
University Hospital Schleswig-HolsteinDeutsche Krebshilfe e.V., Bonn (Germany)CompletedLeukemiaIsrael, Germany, Italy, Australia, Austria, Czechia, Switzerland
-
National Cancer Institute (NCI)NCIC Clinical Trials Group; Southwest Oncology Group; Cancer and Leukemia Group...CompletedClear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage II Renal Cell Cancer AJCC v7 | Stage I Renal Cell Cancer AJCC v6 and v7United States, Canada, Puerto Rico
-
Oxford University Hospitals NHS TrustUniversity of Warwick; University of Birmingham; Janssen-Cilag Ltd.; BloodwiseCompletedMultiple Myeloma | Chronic Kidney DiseaseUnited Kingdom
-
GOG FoundationNational Cancer Institute (NCI)CompletedRecurrent Uterine Corpus Carcinoma | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer AJCC v7 | Stage IIIC Uterine Corpus Cancer AJCC v7 | Stage IVA Uterine Corpus Cancer AJCC v7 | Stage IVB Uterine Corpus Cancer AJCC v7United States, Canada, Japan
-
University of OxfordPfizer; Belfast Health and Social Care Trust; Queen's University, Belfast; Saint... and other collaboratorsCompletedColorectal Cancer | Solid TumorUnited Kingdom
-
David D'Alessio, M.D.Merck Sharp & Dohme LLCCompleted
-
The Clatterbridge Cancer Centre NHS Foundation...Bristol-Myers Squibb; University of LiverpoolActive, not recruitingSquamous Cell Carcinoma of the Oral CavityUnited Kingdom
-
Fred Hutchinson Cancer CenterUniversity of WashingtonCompleted
-
Qianfoshan HospitalJiangsu Hengrui Pharmaceutical Co., Ltd.UnknownImmune Checkpoint InhibitionChina
-
National Cancer Institute (NCI)Eastern Cooperative Oncology Group; Canadian Cancer Trials Group; Southwest Oncology... and other collaboratorsCompletedHER2 Positive Breast Carcinoma | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIA Breast Cancer AJCC v7 | Breast AdenocarcinomaUnited States, Canada, Peru, South Africa
-
Hospices Civils de LyonUnknownMetastatic NRAS MelanomaFrance
-
Dana-Farber Cancer InstituteBristol-Myers SquibbWithdrawnMelanoma Stage IV | Melanoma Stage IIIUnited States
-
Cambridge University Hospitals NHS Foundation TrustAstraZenecaCompletedProstate CancerUnited Kingdom
-
National Cancer Institute (NCI)NRG OncologyCompletedOvarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Fallopian Tube Mucinous... and other conditionsUnited States, Korea, Republic of, Canada, Japan
-
Portland VA Medical CenterNational Cancer Institute (NCI); OHSU Knight Cancer Institute; Oregon State UniversityCompletedProstate Cancer PreventionUnited States
-
The Rogosin InstituteCompleted
-
University of ArizonaCompletedMelanoma | Renal Cell Carcinoma | HCC | Hepatocellular Carcinoma | Metastatic Cancer | Metastatic Melanoma | Colon Cancer | Differentiated Thyroid Cancer | Metastatic Colon CancerUnited States
-
National Cancer Institute (NCI)TerminatedThyroid Neoplasms | Differentiated Thyroid Cancer | Poorly Differentiated and Undifferentiated Thyroid CancerUnited States
-
University of MinnesotaNational Institute of General Medical Sciences (NIGMS)Completed