Search clinical trials for: SINGLE DOSE

Total 25931 results

Latigo Biotherapeutics

Recruiting

A Phase 1 Single and Multiple Ascending Dose Study of LTG-001 Administered Orally in Healthy Participants

Healthy

New Zealand
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers

Bladder Cancer

Australia
Sir Run Run Shaw Hospital

Recruiting

Molecular Basis of Loss Aversion

Healthy

China
ViiV Healthcare

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Suspension Injection of Investigational Capsid Inhibitors Compared to Placebo in Healthy Adults

HIV Infections

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Pharmacokinetic Characterization of a Single 200 mg Dose of Doxycycline in Post-exposure Prophylaxis (PEP) of Sexually Transmitted Infections in Different Biological Compartments (DOXY-PK)

Sexually Transmitted Diseases | Post-exposure Prophylaxis | Doxycycline

France
Instituto do Cancer do Estado de São Paulo

Recruiting

Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma

Multiple Myeloma

Brazil
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

The Effect of Low-dose Interleukin-2 on the Immune Landscape of Human Atherosclerotic Plaques at Single Cell Resolution. (ELLIPSE)

Carotid Artery Plaque | Carotid Atherosclerosis | TIA

United Kingdom
Arxx Therapeutics

Recruiting

A First in Human Study of AX-202 in Healthy Subjects and Patients With Psoriasis.

Healthy Volunteers | Mild to Moderate Psoriasis

United Kingdom
Artery Therapeutics, Inc.
National Institute on Aging (NIA)

Recruiting

Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Alzheimer's Disease

Spain
Yuhan Corporation

Recruiting

A Single Dose, Phase 1 Study of YH35324 in Patients With Various Allergic Diseases

Allergic Disease | Chronic Spontaneous Urticaria | Cold Urticaria | Chronic Inducible Urticaria

Korea, Republic of
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (QTc-ZX-7101A)

Influenza, Human

China
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Recruiting

The Study of Single Dose Administration of GR2002 Injection in Chinese Health Volunteers

Asthma

China
The Affiliated Hospital of Qingdao University

Recruiting

Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial

Gastric Cancer

China
Vertex Pharmaceuticals Incorporated

Not yet recruiting

Evaluation of Efficacy and Safety of a Single Dose of Exa-cel in Participants With Severe Sickle Cell Disease, βS/βC Genotype

Sickle Cell Disease
CSL Behring

Recruiting

First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Complement Deficiencies

Australia
Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
Pfizer

Recruiting

A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults

Healthy Participants

United States
Nanjing Ruijie Pharma Co., Ltd.

Recruiting

Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects

Drug Safety

China
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022

Hyperlipemia

China
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Korea University Anam Hospital

Recruiting

A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke

Dyslipidemias | Stroke, Acute Ischemic

Korea, Republic of
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants

Healthy Participants

United States
The Affiliated Hospital of Qingdao University

Recruiting

XKDCT080 in GCC-positive Recurrent or Refractory Solid Tumors With Single Center, Single Arm, and Dose Escalation

Colon Cancer

China
Immunocore Ltd

Recruiting

Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Taiwan, Denmark, United States, Australia, Romania, United Kingdom, Spain
HealthPartners Institute

Recruiting

Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose (INI-CSF)

Healthy

United States
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease (BUSTON-01)

Dry Eye Disease
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease (BUSTON-02)

Dry Eye Disease
Aer Therapeutics

Recruiting

Single and Multiple Ascending Dose Study of AER-01

COPD

Australia
Medical College of Wisconsin
University of Oklahoma

Recruiting

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage (TheoPHyLNNe)

Acute Kidney Injury | HIE

United States
Abdul El-Rabbany

Recruiting

Antibiotics for Prevention of Infection Following Orthognathic Surgery

Orthognathic Surgical Site Infection

Canada
Sirnaomics

Recruiting

Single Ascending Dose of FXI-GalNAc-siRNA in Healthy Subjects

FXI

United States, Canada
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
Federal University of Health Science of Porto Alegre

Not yet recruiting

Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS (L-AmB_phase3)

Fungal Infection | Immunosuppression | AIDS and Infections | Disseminated Histoplasma Capsulatum Infection

Brazil
David D'Andrea

Not yet recruiting

Single-Dose Intravesical Chemotherapy After Diagnostic URS (MINERVA)

Bladder Cancer | Upper Urinary Tract Urothelial Carcinoma

Austria
Peking University Third Hospital

Not yet recruiting

Single Ultra-high Dose Stereotactic Body Radiation Therapy for Early Lung Cancer (USBRT-1)

Stereotactic Body Radiotherapy | Early Lung Cancer

China
Brigham and Women's Hospital
Bill and Melinda Gates Foundation

Not yet recruiting

A Single-Dose, Three-Way, Three-Sequence, Crossover BA Study of Azithromycin Oleogel

Infectious Disease | Drug Effect | Clinical Infection
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Study of HS-10517 in Chinese Adult Participants

COVID-19

China
Ciusss de L'Est de l'Île de Montréal

Recruiting

Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block (DEXBIB)

Shoulder Pain | Anesthesia | Post Operative Pain

Canada
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

Influenza

United States
Biocad

Recruiting

Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL) (BLUEBELL)

Spinal Muscular Atrophy (SMA)

Belarus, Russian Federation
McMaster University
Center for Medicinal Cannabis Research

Recruiting

The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol (POT-GFR-PK)

Chronic Kidney Diseases | Cannabis | Dialysis

Canada
Zuyderland Medisch Centrum
AtriCure, Inc.

Recruiting

Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (ICE)

Funnel Chest | Pectus Excavatum

Netherlands
Nirsum Labs
National Institute on Drug Abuse (NIDA)

Recruiting

Single Ascending Dose Study of NRS 033 in Healthy Volunteers

Healthy Volunteers

United States
First Affiliated Hospital, Sun Yat-Sen University
Baxter Healthcare Corporation

Recruiting

Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis

Peritoneal Dialysis

China
University of Reading
Wild Blueberry Association of North America (WBANA)

Recruiting

Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults

Executive Function | Mood | Affect

United Kingdom
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Escalating Doses of SIM0348 as a Single Agent in Advanced Solid Tumors

Advanced Solid Tumors
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers

Healthy

Korea, Republic of
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy (HYPOGRYPHE)

Melanoma | Renal Cell Carcinoma | NSCLC | SCLC | Breast Carcinoma | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Brain Metastases, Adult

United States

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