Search clinical trials for: Single Gene Polymorphism

Total 275131 results

Children's Mercy Hospital Kansas City
University of Kansas

Completed

Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology

Brain Injury | Respiratory Failure | Necrotizing Enterocolitis | Lung Disease

United States
University of Sao Paulo

Unknown

Genetic Association Study Between Single Nucleotide Polymorphisms (SNPs) and Cognitive Performance in Young Bipolar Type I Patients: LICAVALGENE (Licavalgene)

Bipolar

Brazil
Samsung Medical Center

Unknown

Genetic Predictive Model Based on Single Nucleotide Polymorphisms in the DNA Repair Pathway and Drug Metabolis/Transport Pharmacogenetics in the Prediction of Response and Treatment Outcomes in Acute Myeloid Leukemia

Patients With Acute Myeloid Leukemia | Patients Receiving Induction/Consolidation Chemotherapy

Korea, Republic of
China Medical University Hospital

Unknown

The Relationship Between Single Nucleotide Polymorphisms of Chitinase 3-like 1 Gene,YKL-40 Serum Levels and Adult Asthma (CHI3L1)

Asthma

Taiwan
National Taiwan University Hospital

Unknown

Association of Genetic Polymorphisms With Lipid Lowering Effects of Statin Therapy

Single Nucleotide Polymorphism | Statins, HMG-CoA

Taiwan
University of Brasilia

Completed

Low-dose Pentavalent Antimony Treatment of Cutaneous Leishmaniasis in Old Age Patients (Sbold)

Localized Cutaneous Leishmaniasis

Brazil
UConn Health
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Completed

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

Alcoholism | Alcohol Related Disorders | Alcohol Abuse

United States
Sociedad Española de Neumología y Cirugía Torácica
Spanish Research Center for Respiratory Diseases

Unknown

NADPH Oxidase Polymorphisms in Obstructive Sleep Apnea Syndrome (OSAS)

Oxidative Stress | Single Nucleotide Polymorphism | Sleep Apnea Syndrome

Spain
Chang Gung Memorial Hospital

Unknown

Immunological Change and the Single Nucleotide Polymorphism (SNP) in Children With Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome | Children

Taiwan
Samsung Medical Center

Unknown

Genome-wide Pharmacogenetic Candidate Gene Single Nucleotide Polymorphism (SNP) Array-based Approach to Predict Chemoresponse and Survival in Patients With Acute Myeloid Leukemia With Normal Karyotype

Myeloid Leukemia

Korea, Republic of
Chungnam National University
Korea Healthcare Technology R&D Project; Korea Advanced Institute of Science...

Completed

Investigation of Genetic Disease Marker Associated With Korean Glaucoma Patients

Single-nucleotide Polymorphism (SNP) for Glaucoma

Korea, Republic of
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

To Study the Effects of Host Genetic Factors on Liver Cirrhosis and Hepatocellular Carcinoma (HCC)

Liver Cirrhosis

Taiwan
Seoul National University Hospital
Korea Health Industry Development Institute

Unknown

Methylphenidate Treatment Response Study of Genetic Polymorphism in Attention Deficit Hyperactivity Disorder(ADHD)

Attention Deficit Hyperactivity Disorder

Korea, Republic of
Min-Sheng General Hospital
National Taiwan University Hospital

Unknown

Use Cord Blood Single Nucleotide Polymorphism to Predict the Later Development of Atopy and Allergy

Atopy | Allergic Disease

Taiwan
Interleukin Genetics, Inc.

Unknown

A to Z Study Follow-up: Collection of DNA Data From Buccal Swabs

Obesity | Weight Management | Dietary Recommendations | Diet Conditions | Overweight Management

United States
National Cancer Institute (NCI)
Multicenter AIDS Cohort Study (MACS)

Completed

Genetics of Progressive Multifocal Leukoencephalopathy and Acquired Immunodeficiency Syndrome

AIDS | PML

United States
Genomas, Inc
University of Kentucky; Hartford Hospital

Unknown

DNA Diagnostics for Minimizing Metabolic Side-Effects of Antipsychotics (DIMS)

Psychoses

United States
Maaynei Hayesha Medical Center

Unknown

Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Hyperandrogenism | Single Nucleotide Polymorphism | Anovulation

Israel
BioNTech SE

Not yet recruiting

A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial Vaginosis

Bacterial Vaginosis

United States
Xin-Hua Xu

Recruiting

A Prospective, Open-label, Single-center, Single-arm Phase II Clinical Study of Cadonilimab (AK104) Combined With Monotherapy Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer With Negative Driver Genes and Failed Immunotherapy

Non-small Cell Lung Cancer

China
Peking University People's Hospital

Not yet recruiting

Fertility Sparing Therapy for Patients With Stage IA G2 Endometrial Cancer

Carcinoma, Endometrioid | Fertility Preservation
Marmara University

Recruiting

Evaluation of Inflammasome Gene Polymorphisms in Periodontitis Patients

Periodontitis | Periodontal Diseases

Turkey
Assiut University

Not yet recruiting

Osteopontin Gene Polymorphism in Stroke Patients in Egypt

Ischemic Stroke
European Organisation for Research and Treatment...

Not yet recruiting

OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT) (SPRINT)

Breast Cancer | Colorectal Cancer | NSCLC | Prostate Cancer | Oligometastatic Disease
Pfizer
AbbVie

Not yet recruiting

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH) (CHERISH)

Gram-negative Bacterial Infection
University of Calgary
University of Toronto; Precisio Biotix Therapeutics, Inc.

Not yet recruiting

Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection (PHAGE-2024-01)

Staphylococcus Aureus Infection | Prosthetic Joint Infections of Hip
University of Monastir

Not yet recruiting

mRNA Expression and Genetic Polymorphisms Affecting DRD3 (rs6280) and HTR2A (rs6313) in Bruxism

Bruxism
Rejukon Biopharm Inc.

Not yet recruiting

An IIT Clinical Study to Evaluate the Safety and Efficacy of a Single Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis
LEO Pharma

Not yet recruiting

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Joint Pain | Gout Flares | Joint Inflammation
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Predictive Determinants of Nephrotic Syndrome Remission in Patients With At-risk Polymorphism of APOL1 (NEPHROL1)

Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | APOL1 Associated Kidney Disease

France
Eli Lilly and Company

Not yet recruiting

Lebrikizumab Pen Ease of Use in Participants With Atopic Dermatitis

Atopic Dermatitis

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial

Carpal Tunnel Syndrome

China
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Brown University
National Institute of Mental Health (NIMH)

Recruiting

Cognitive Control & the Functional Organization of the Frontal Cortex

Healthy Volunteers | Executive Function | Multitasking Behavior and Neural Representations Associated With Multitasking Ability

United States
Sir Run Run Shaw Hospital

Not yet recruiting

A Study of SBRT Combined With Puterizumab in Intrapulmonary Metastasis From NSCLC

Non-Small-Cell Lung Cancer
Hong Kong Baptist University

Not yet recruiting

The Effect of Traditional Chinese Cervical Manipulation for Cervicogenic Headache: a Pilot Randomized, Single-blind, Placebo-controlled Trial

Cervicogenic Headache

Hong Kong
Innovative Molecules GmbH

Recruiting

Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers

Herpes Simplex Virus

Germany
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

A Study of Single and Multiple Doses HRS9531 Tablets in Healthy Subjects

Overweight or Obesity; Type 2 Diabetes

China
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Longitudinal Study of Gene Expression in the Human Placenta During First-trimester and Full-term Pregnancy at the Single Cell Level (VilliRNAseq)

Pregnancy Related

France
Qompium NV

Recruiting

Combining Accelerometer, Gyroscope, Sound, Electrocardiography and Photoplethysmography Data in Cardiac Monitoring (CARDS-pilot)

Atrial Fibrillation

Belgium
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Ospedale San Raffaele

Recruiting

Genetics in the Progression of Nephropathies

Hypertension | AKI | CKD | Hematologic Malignancy | Ckd-Mbd | ADPKD | Bone Marrow Transplant Complications | CKD (Chronic Kidney Disease) Stage 5D

Italy
Tianjin Medical University Cancer Institute and...

Recruiting

The Safety and Effectiveness of NEPA in Preventing Postoperative Nausea and Vomiting After General Anesthesia Gastrointestinal Cancer Surgery: A Single-Center Retrospective Study

General Anesthesia Gastrointestinal Cancer Surgery

China
Beijing Tiantan Hospital

Recruiting

Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅳ(TRACE Ⅳ)

Minor Ischemic Stroke | Tenecteplase

China
University of Calgary

Recruiting

Evaluating the Impacts of a Single Session of Robot Assisted Gait Training With a Trexo

Physical Disability | Developmental Disability | CP (Cerebral Palsy)

Canada
Wave Life Sciences Ltd.

Recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency

Canada
Tianjin Medical University Cancer Institute and...

Recruiting

Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study

Pancreatic Cancer

China
Gazi University

Recruiting

Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects

Gingival Recession, Localized

Turkey
Hospital Nossa Senhora da Conceicao

Not yet recruiting

ARISCAT, ASA and LAS VEGAS Risk Scores and the Incidence of Postoperative Pulmonary Complications in Thoracic Surgery

Postoperative Complications

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