Search clinical trials for: Soluble urokinase plasminogen activator receptor

Total 18995 results

Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
Technische Universität Dresden
GWT-TUD GmbH

Recruiting

COMPERA / COMPERA-KIDS (COMPERA)

Pulmonary Arterial Hypertension (PAH) | Pulmonary Hypertension (PH)

Germany, Belgium, Italy, Switzerland
NHS Greater Glasgow and Clyde
University of Edinburgh; Oxford University Hospitals NHS Trust; University of...

Completed

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST2)

Ischemic Stroke

United Kingdom
Rigshospitalet, Denmark
University Hospital Bispebjerg and Frederiksberg; Hillerod Hospital, Denmark; Herlev and Gentofte Hospital and other collaborators

Active, not recruiting

Low Dose Thrombolysis, Ultrasound Assisted Thrombolysis or Heparin for Intermediate High Risk Pulmonary Embolism (STRATIFY)

Pulmonary Embolism

Denmark
Boehringer Ingelheim

Completed

A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 (TRISTARDS)

Acute Respiratory Distress Syndrome

Spain, Germany, Italy, Belgium, Mexico, Netherlands, India, France, Malaysia, Austria, Brazil, Russian Federation, Turkey
Memorial Healthcare System
Genentech, Inc.

Completed

Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis

Pleural Effusion

United States
Memorial Sloan Kettering Cancer Center
NYU Langone Health; National Institutes of Health (NIH); Weill Medical College... and other collaborators

Completed

Combination of Serum Measurements of Molecular Biomarkers and Serum Protein Profiling Can be Used to Predict Which Patients Undergoing Prostatic Biopsy Will be Diagnosed With Cancer

Prostate Cancer | Elevated Prostate Specific Antigen (PSA)

United States
University Hospital, Caen

Suspended

Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Subarachnoid Hemorrhage

France
Angde Biotech Pharmaceutical Co., Ltd.
Beijing Tiantan Hospital

Completed

A Study of r-PA Treating Patients With Acute Ischemic Stroke（RAISE）

Acute Ischemic Stroke

China
University of Florida

Completed

Fibrinolytic Therapy Versus Medical Thoracoscopy

Pleural Diseases

United States
Palobiofarma SL
Ohio State University

Active, not recruiting

PBF-1129 in Patients With NSCLC

Locally Advanced or Metastatic NSCLC

United States
Azienda U.S.L. 1 di Massa e Carrara

Withdrawn

Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary Embolism (MONALYSE)

Pulmonary Embolism
Bayer

Completed

Prospective, Non-interventional, Multi-center, Post-authorization Safety Study of Riociguat for Pulmonary Arterial Hypertension (PAH) (JPMS-PAH)

Hypertension, Pulmonary

Japan
Nantes University Hospital

Completed

A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion (THEIA)

Central Retinal Artery Occlusion

France
Boehringer Ingelheim

Completed

A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity (ORIGINAL)

Stroke

China
Bayer

Completed

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH. (CHEST-1)

Pulmonary Hypertension

Belgium, France, Spain, Turkey, Portugal, Taiwan, Japan, United States, Switzerland, Korea, Republic of, Austria, Canada, China, Denmark, Germany, Russian Federation, Mexico, Argentina, Netherlands, Italy, Poland, United Kingdom, Au... and more
The First Affiliated Hospital of Zhengzhou University
General Hospital of Shenyang Military Region; Beijing Tiantan Hospital; Shanghai...

Completed

Thrombolysis of Urokinase for Minor Stroke (TRUST)

Minor Stroke

China
Centre Hospitalier Sud Francilien

Completed

Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study (DIVArétro)

Acute Ischemic Stroke Due to Medium-vessel-occlusion

France
Bayer

Completed

BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension (CHEST-2)

Pulmonary Hypertension

Belgium, France, Spain, Turkey, Portugal, Taiwan, Japan, United States, Switzerland, Korea, Republic of, Austria, Canada, China, Denmark, Germany, Mexico, Russian Federation, Argentina, Italy, Poland, Australia, Brazil, Czechia, United... and more
Centre Hospitalier Sud Francilien

Completed

Tirofiban Plus Intravenous Thrombolysis in Acute Anterior Choroidal Infarction or Paramedian Pontine Infarction (TITACIPPI)

Acute Anterior Choroidal Infarction (ACI) | Paramedian Pontine Infarction (IPP)

France
University of Michigan
Genentech, Inc.

Completed

Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis (PLATyPuS)

Healthy | Protein-Losing Enteropathies | Plastic Bronchitis

United States
Boehringer Ingelheim

Completed

SITS-IVT in Patients >80 Years Study (SITS_ELDERLY)

Ischaemic Stroke

Sweden
Kafrelsheikh University

Completed

Predictors of AIS Unfavorable Outcomes

Ischemic Stroke | Alteplase Adverse Reaction

Egypt
Indiana Hemophilia &Thrombosis Center, Inc.

Active, not recruiting

Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency

Plasminogen Activator Inhibitor-1 Deficiency | Cardiac Fibrosis

United States
Cellectis S.A.

Terminated

Study Evaluating Safety and Efficacy of UCART Targeting CS1 in Patients With Relapsed/Refractory Multiple Myeloma (MELANI-01)

Relapsed/Refractory Multiple Myeloma

United States
Bayer

Terminated

Study to Find the Highest Safe Dose of Soluble Guanylate Cyclase (sGC) Activator, BAY 1211163 Administered as Multiple Doses by Inhalation to Patients Who Cannot Breathe by Their Own and Suffer From a Type of Lung Failure That Causes Fluid to Build up in the Lungs Making Breathing Difficult (ARDS)

Acute Respiratory Distress Syndrome

Germany
Haukeland University Hospital

Terminated

The Norwegian Tenecteplase Stroke Trial 2 (NOR-TEST 2)

Cerebrovascular Disorders | Ischemic Stroke | Stroke, Acute

Norway
Ge Junbo

Terminated

Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention (RECOVERII)

Acute ST-segment Elevation Myocardial Infarction

China
The University of Texas Health Science Center,...

Completed

Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization (PATCAR)

Myocardial Infarction | Heart Disease | Acute Myocardial Infarction

United States
Texas Tech University Health Sciences Center, El...

Completed

Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED) (VOMIITED)

Nausea | Vomiting

United States
Chiesi Farmaceutici S.p.A.

Terminated

Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality (READY 1)

Thrombosis | Catheter Occlusion

United States, Argentina, Belgium, Czechia, Poland, Romania, Spain
Supergene, LLC

Completed

Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE

Massive Pulmonary Embolism

Russian Federation
Life Recovery Systems
Geisinger Clinic; Tulane University School of Medicine

Terminated

Helping Stroke Patients With ThermoSuit Cooling (SISCO)

Stroke | Brain Ischemia

United States
Northwestern University

Suspended

Study To antagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19

Covid19

United States
University of Calgary

Completed

Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke (AcT)

Stroke, Acute | Thromboses, Intracranial

Canada
Boehringer Ingelheim

Completed

A Study in Healthy Men to Compare 2 Different Formulations of Alteplase

Healthy

Germany
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Surgical Stabilizer Assisted RVC With rtPA for CRVO

Central Retinal Vein Occlusion

Belgium
Northwell Health

Completed

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

Thromboembolism | Pulmonary Hypertension | Pulmonary Embolism | Right Ventricular Dysfunction

United States
Al-Azhar University

Completed

Evaluation Efficacy of Melatonin Gel as Adjunctive Therapy in Chronic Periodontitis

Chronic Periodontitis

Egypt
University Hospital Inselspital, Berne
Medtronic

Completed

Bridging Thrombolysis Versus Direct Mechanical Thrombectomy in Acute Ischemic Stroke (SWIFT DIRECT)

Ischemic Stroke

Spain, France, Germany, Canada, United Kingdom, Austria, Finland, Switzerland
GrandPharma (China) Co., Ltd.

Active, not recruiting

A Study Evaluating the Safety and Efficacy of Tirofiban in Combination With Alteplase in Acute Ischemic Stroke (RESET)

Acute Ischemic Stroke

China
Centre Hospitalier Sud Francilien

Completed

Impact of the Rapid Normalization of Chronic Hyperglycemia and the Practice of Moderate Physical Activity on the "Receptor Activator of Nuclear Factor-kappa B Ligand / Osteoprotégérine (RANKL / OPG) System in Patients Living With Type II Diabetes (RANKL-GLYC)

Type II Diabetes

France
Beijing Tiantan Hospital
Guangzhou Recomgen Biotech Co., Ltd.

Completed

Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-Ⅱ (TRACEⅡ)

Acute Ischemic Stroke

China
General Hospital of Shenyang Military Region

Completed

EXtending the tIme Window of Thrombolysis by ButyphThalide up to 6 Hours After Onset (EXIT-BT)

Stroke, Ischemic

China
Boehringer Ingelheim

Completed

1-year Clinical Outcomes in Recombinant Tissue Plasminogen Activator (Rt-PA) Treated Chinese Acute Ischaemic Stroke (AIS) Patients

Stroke

China
Haseki Training and Research Hospital
Saglik Bilimleri Universitesi

Completed

The Potential Role of sRAGE, KL-6, and SP-D as Prognostic Factors in Children With COVID-19

Pneumonia, Viral | Children | SARS CoV 2 Infection | Alveolar; Injury

Turkey
Assiut University
Aswan University Hospital

Completed

TPA in Acute Stroke With COVID Verus Non-COVID-19 Patients (rTPA)

Acute Ischemic Stroke

Egypt
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States
University of Erlangen-Nürnberg Medical School

Completed

Stroke Research Consortium in Northern Bavaria (STAMINA) (STAMINA)

Ischemic Stroke

Germany
Dokuz Eylul University

Completed

Evaluation of the Intravenous Tissue Plasminogen Activator Treatment Algorithm of Nursing Intern Students

Acute Stroke

Turkey

Search clinical trials for: Soluble urokinase plasminogen activator receptor

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