Search clinical trials for: TKI-258,

Total 557 results

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase II Trial of Camrelizumab in Combination With Apatinib for Neoadjuvant Treatment of Early-stage TNBC With a High Proportion of TILs

Breast Cancer | Triple-Negative Breast Cancer

China
Hanmi Pharmaceutical Company Limited

Completed

Phase I/II Trial to Evaluate Safety, Tolerability and Pharmacokinetic Profile of HM61713 in NSCLC Patients

Non Small Cell Lung Cancer

Korea, Republic of
University of Florida

Withdrawn

Explore the Synergy of Combination TKI Therapy

Healthy Volunteers
Peking University Third Hospital

Unknown

Endostar Combination With Chemotherapy and EGFR-TKI in Lung Cancer Rechallenging Treatment After Acquired Resistance.

Lung Cancer

China
Beta Pharma Shanghai

Active, not recruiting

A Study of BPI-7711 Capsule in Non-small Cell Lung Cancer Patients

NSCLC

China
Peking University Cancer Hospital & Institute

Recruiting

A Study of Ensartinib as Neoadjuvant Therapy for Patients With ALK Positive Resectable Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

China
Guangdong Association of Clinical Trials

Unknown

Pemetrexed vs Pemetrexed Plus Cisplatin in EGFR-mutant NSCLC Patients After First Line EGFR-TKIs Failure

Non-small Cell Lung Cancer

China
Tongji University
Sun Yat-sen University; Peking Union Medical College Hospital; RenJi Hospital; Guangdong... and other collaborators

Completed

Erlotinib Versus Gemcitabine/Carboplatin in Chemo-naive Stage IIIB/IV Non-Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Exon 19 or 21 Mutation (ML20981)

Non-small Cell Lung Cancer

China
University of Manitoba
Manitoba Health

Recruiting

Supporting Healthcare Improvement Through Facilitation & Training (SHIFT)

Frontline Staff Working Within Personal Care Home Facilities

Canada
Mayo Clinic

Enrolling by invitation

The Effect of Ablation Therapy on Barrett's Esophagus (ablation IN BE)

Barrett's Esophagus | Early Esophageal Adenocarcinoma

United States
Massachusetts General Hospital

Completed

Improving Care After Chemotherapy (IMPACT)

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of a Live Attenuated Human Parainfluenza Virus Type 2 (HPIV2) Vaccine for Adults, Children, and Infants

Human Parainfluenza Virus 2

United States
Sunnybrook Health Sciences Centre

Completed

Early Prevention of Post Traumatic Stress Disorder

Post Traumatic Stress Disorder

Canada
Erasmus Medical Center

Recruiting

ProSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors (START-TKI) (START-TKI)

Non Small Cell Lung Cancer | Liquid Biopsy | Tyrosine Kinase Inhibitor

Netherlands
The University of Hong Kong

Completed

Afatinib vs Erlotinib as 2nd TKI After Failure to 1st TKI and Chemotherapy for Metastatic NSCLC

Lung Cancer

Hong Kong
The Fourth Affiliated Hospital of Zhejiang University...

Completed

Efficacy of Targeted Therapy Combined Chemotherapy in Advanced EGFR Positive NSCLC Patients

NSCLC | EGFR Gene Mutation | Non-small-lung-cell Cancer

China
Hunan Province Tumor Hospital

Recruiting

Erlotinib Combined With Chemotherapy in TKI Resistant Non-Small Cell Lung Cancers

Carcinoma, Non-Small Cell Lung | EGFR Gene Mutation

China
Novartis Pharmaceuticals

Completed

Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) Inhibitor

Gastrointestinal Stromal Tumors (GIST)

Israel
Hellenic Oncology Research Group
University Hospital of Crete

Terminated

Combination of Erlotinib and Bevacizumab as Second-line Treatment in Patients With Non-small Cell Lung Cancer

Non-small-cell Lung Cancer

Greece
Thomas Jefferson University
Rutgers University; West Chester University of Pennsylvania

Active, not recruiting

Project MiNT: Assessing the Impact of Food & Video-Based Nutrition Education on Patients With Poorly Controlled Diabetes

Diabetes Mellitus, Type 2

United States
Gulhane Training and Research Hospital

Completed

COVID-19 Pandemic and General Surgery Emergencies

Emergencies

Turkey
AbbVie

Withdrawn

A Blood and Tissue Sample Collection Study of Patients Who Have Inflammatory Bowel Disease, Who Have Been Treated With Adalimumab and Who Developed Hepatosplenic T-Cell Lymphoma (HSTCL)

Crohn's Disease | Hepatosplenic T-Cell Lymphoma | Ulcerative Colitis (UC)

Italy
Masaryk Hospital Krajská zdravotní a.s.

Unknown

Duplex Ultrasonography Performed by Nurses

Catheter Related Complication

Czechia
M.D. Anderson Cancer Center

Completed

Temozolomide and SCH66336 for Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Centro de Investigacion Sanitaria
University of Helsinki; International Diabetes Federation

Completed

DEMOJUAN- DEMOnstration Area for Primary Prevention of Type 2 Diabetes, JUAN Mina and Barranquilla, Colombia (DEMOJUAN)

Glucose Metabolism Disorders | Type 2 Diabetes

Colombia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Measurement of Digital Colposcopy for Fluorescence Spectroscopy of Cervical Intraepithelial Neoplasia

Cervical Cancer

United States, Canada, Nigeria
Centre Hospitalier Universitaire de Liege

Recruiting

PROspective Trial on EOsinophilia in Non-Small Cell Lung Cancer (NSCLC). (PROTEON)

Non-small Cell Lung Cancer

Belgium
Memorial Sloan Kettering Cancer Center

Active, not recruiting

PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer

Thyroid Cancer, Follicular | Thyroid Cancer | Papillary Thyroid Cancer | Poorly Differentiated Thyroid Gland Carcinoma | Follicular Thyroid Cancer | Hurthle Cell Tumor | Hurthle Cell Thyroid Neoplasia

United States
Beth Israel Deaconess Medical Center

Active, not recruiting

Cisplatin vs. Doxorubicin/Cyclophosphamide in BrCa

Breast Cancer

United States
Incyte Corporation

Completed

Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF)

MPN (Myeloproliferative Neoplasms)

United States
William Beaumont Hospitals

Withdrawn

Near-Infrared Spectroscopy and Ultrasound Investigation of Coronary Artery Plaque (LUNAR)

Coronary Artery Disease | Atherosclerosis

United States
University of Michigan
University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

A Randomized Trial of GM-CSF in Patients With ALI/ARDS

Respiratory Distress Syndrome, Adult

United States
University of Florida

Completed

Resistance Exercise Effects on Fear Avoidance and Physical Function in Obese Older Adults With Low Back Pain

Obesity | Low Back Pain

United States
Shanghai Pulmonary Hospital, Shanghai, China

Unknown

EGFR-TKI With/Without Chemotherapy in NSCLC Patients With Both EGFR Mutation and BIM Deletion Polymorphism

Nonsmall Cell Lung Cancer | EGFR Gene Mutation
Summit Therapeutics
Department of Health and Human Services

Terminated

Safety, Tolerability and the Pharmacokinetics of Ridinilazole in Adolescent Subjects (Ri-CoDIFy 3)

Clostridioides Difficile Infection

United States
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Phase II Clinical Study of T-DM1 and Pyrotinib Maleate in Patients With HER2-positive Metastatic Breast Cancer Who Had Progressed on TKI Therapy

HER2+ Advanced Breast Cancer Patients Progressing on TKI Therapy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Adebrelimab and a TKI in Combination With GEMOX in First-line Treatment of Advanced Biliary Tract Cancers (BTC)

Biliary Tract Cancer | Gemox Chemotherapy

China
Kanazawa University

Unknown

Phase I of Vorinostat-Iressa Combined Therapy on Resistance by BIM Polymorphysim in EGFR Mutant Lung Cancer (VICTORY-J)

Non-Small-Cell Lung Carcinoma

Japan
Shanghai Cancer Hospital, China

Unknown

Efficacy and Safety of Platinum-based Chemotherapy + Bevacizumab + Durvalumab, and Salvage SBRT for IV Non-Small Cell Lung Cancer Patients With EGFR Mutations After Failure of First Line Osimertinib: A Multicenter, Prospective, Phase II Clinical Study

Lung Cancer Stage IV，EGFR-mutant，TKI，PD-L1，SBRT

China
Betta Pharmaceuticals Co., Ltd.

Unknown

High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases

Non-small Cell Lung Cancer | Brain Metastases

China
Betta Pharmaceuticals Co., Ltd.

Completed

Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation

Non-small Cell Lung Cancer | Brain Metastases

China
University Hospital, Bordeaux

Recruiting

Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors (SPICI)

Metastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score

France
Peking Union Medical College Hospital

Recruiting

Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer

Hepatocellular Carcinoma

China
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Withdrawn

Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma
Di Wu

Not yet recruiting

Study of Anlotinib Hydrochloride and Toripalimab in Subjects With Unresectable or Metastatic Undifferentiated Pleomorphic Sarcoma

Undifferentiated Pleomorphic Sarcoma | Soft Tissue Sarcomas

China
Berry Genomics Co., Ltd.
Shanghai Chest Hospital; Baotou Cancer Hospital

Unknown

cSMART Liquid Biopsy and Dynamic Monitor of NSCLC Patients in Inner-Mongolia China

Adenocarcinoma | Nonsmall Cell Lung Cancer

China
Chongqing University Cancer Hospital

Recruiting

Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC

Non-Small Cell Lung Cancer (NSCLC)

China
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment

Renal Cell Carcinoma
Lady Davis Institute

Recruiting

Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI

Acneiform Eruptions | Cancer, Treatment-Related

Canada
Hangzhou Cancer Hospital

Unknown

RT Plus EGFR-TKI for Wild-type NSCLC

Non-small Cell Lung Cancer | Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI)

China

Search clinical trials for: TKI-258,

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