Search clinical trials for: Vigamox, topical antibiotics, Intravitreal injections, macular degeneration, endophthalmitis

Total 6246 results

Bayer
Regeneron Pharmaceuticals

Completed

Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye (ARIES)

Macular Degeneration

Spain, Hungary, United Kingdom, Australia, Italy, Canada, France, Germany
Bayer
Regeneron Pharmaceuticals

Completed

Routine Clinical Practice for Use of Intravitreal Aflibercept Treatment in Patients With Diabetic Macular Edema (APOLLON)

Diabetic Retinopathy

France
Ospedale Santa Croce-Carle Cuneo

Completed

M Charts Versus Amsler Test in Evaluating Metamorphopsia in nAMD (MVAinAMD2022)

Metamorphopsia | Macular Degeneration, Wet

Italy
Assiut University

Active, not recruiting

Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients With Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF Injection

Macular Edema | Retinal Vein Occlusion

Egypt
Larkin Community Hospital

Completed

Role of Intravitreal Aflibercept Injection for the Treatment of Radiation Maculopathy

Adverse Effect of Radiation Therapy
Imperial College London

Withdrawn

Combined Ranibizumab and Iluvien for Diabetic Macular Oedema (CASSIE)

Diabetes | Diabetic Macular Edema
European School of Advanced Studies in Ophthalmology

Completed

Diabetic Macular Edema: Relevance of Staging Progression on Therapeutic Outcome

Diabetic Macular Edema

Switzerland
East Kent Hospitals University NHS Foundation Trust

Completed

Retinal Oximtery Following Treatment for Diabetic Maculopathy

Diabetic Maculopathy
Hoffmann-La Roche

Active, not recruiting

A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm (PAVILION)

Diabetic Retinopathy

United States, Puerto Rico
University of Nebraska
Regeneron Pharmaceuticals

Completed

Pharmacokinetic Study of Intravitreal Aflibercept Injection in Eyes With Wet Age-related Macular Degeneration (DRAW)

Neovascular Macular Degeneration

United States
Universidade Federal de Goias

Completed

Evaluation of Retina in Patients With Glaucoma Using Topical Prostaglandins Undergoing Trabeculectomy Surgery (TRAB)

Glaucoma

Brazil
Greater Houston Retina Research
Regeneron Pharmaceuticals; Clinical Trials Resource Group, LLC

Active, not recruiting

Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial (VOYAGE)

Diabetic Retinopathy

United States, Puerto Rico
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for DME (INFINITY)

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for Wet AMD (OPTIC)

Neovascular Age-related Macular Degeneration | Wet Age-related Macular Degeneration

United States
Innovent Biologics (Suzhou) Co. Ltd.

Suspended

Evaluation of IBI302 Injection in nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

China
JHSPH Center for Clinical Trials
National Eye Institute (NEI)

Completed

Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial (MERIT)

Uveitis | Macular Edema

United States, Australia, Canada, India, United Kingdom
Apellis Pharmaceuticals, Inc.

Completed

A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration

Geographic Atrophy

United States, France, Italy, Netherlands, Israel, Germany, United Kingdom, Spain, Australia, New Zealand, Poland, Brazil, Canada, Czechia
Alimera Sciences

Active, not recruiting

A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME) (NEW DAY)

Diabetic Macular Edema

United States
Apellis Pharmaceuticals, Inc.

Completed

Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration

Geographic Atrophy

Italy, Germany, United States, Israel, United Kingdom, France, Canada, Czechia, Australia, Spain, Argentina, New Zealand, Poland, Brazil, Puerto Rico
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National... and other collaborators

Completed

Anti-VEGF Treatment for Prevention of PDR/DME

Diabetic Retinopathy | Diabetic Macular Edema

United States, Canada
Novartis Pharmaceuticals

Completed

To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema (KINGLET)

Diabetic Macular Edema

China
University of Wisconsin, Madison

Completed

Control of Pain in Intravitreal Injections Using Topical NSAIDs (COPIVIN)

Intravitreal Injections | IVI

United States
SurModics, Inc.

Completed

Safety and Tolerability Study of the Helical Intravitreal Triamcinolone Implant in Diabetic Macular Edema (STRIDE)

Diabetic Macular Edema

United States
Bayer

Completed

Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice

Wet Age-related Macular Degeneration

India
Ribomic USA Inc

Completed

A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration (RAMEN)

Exudative Age-related Macular Degeneration

United States
OcuTerra Therapeutics, Inc.

Completed

Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration

United States
Centre Hospitalier Intercommunal Creteil
Bayer

Active, not recruiting

CNV in AMD Analyzed by OCT Angiography Under IntravitreaL Eylea (COCTAEyl) (COCTAEyl)

AMD | Exudative Macular Degeneration

France
Bayer
Regeneron Pharmaceuticals

Completed

Observational Study to Assess Intravitreal Aflibercept Injections Used in a "Treat and Extend" Regimen in Treatment-naïve Wet Age-related Macular Degeneration Patients (ASTERIA)

Wet Age-related Macular Degeneration

Switzerland
OcuTerra Therapeutics, Inc.

Completed

Safety and Exploratory Efficacy Study of SF0166 for the Treatment of Diabetic Macular Edema (DME)

Diabetic Macular Edema

United States
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial Kit

Neovascular Age-related Macular Degeneration (nAMD)

United States
Dar El Oyoun Hospital

Completed

Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal Deta Chment in Central Serous Chorioretinopathy (CSCR)

Central Serous Chorioretinopathy

Egypt
Dar El Oyoun Hospital

Completed

Intravitreal Dexamethasone Implant for Refractory Diabetic Macular Edema:

Diabetic Macular Edema

Egypt
Damascus University

Completed

Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.

Cataract | Intravitreal Injection | Diabete Type 2 | Triamcinolone Acetonide

Syrian Arab Republic
University of Oklahoma

Completed

The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections

Age-Related Macular Degeneration | Diabetic Macular Edema | Intravitreal Injection | Ocular Rinse | Cystoid Macular Edema

United States
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison

Completed

A Randomized, Double-masked, Multicenter,Sham-controlled, Safety and Efficacy Study of KH902 in Patients With Wet AMD (PHOENIX)

Neovascular Age-related Macular Degeneration

China
Instituto Universitario de Oftalmobiología Aplicada...
Fondo de Investigacion Sanitaria

Completed

Efficacy and Safety Study of Intravitreal Triamcinolone to Treat Diffuse Diabetic Macular Edema

Diabetes Mellitus | Macular Edema

Spain
Hoffmann-La Roche

Completed

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of RO7303359 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

Geographic Atrophy

United States
AbbVie

Completed

A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina

Macular Edema

United States
Novartis Pharmaceuticals

Terminated

Brolucizumab Treatment Experience Study of Patients With nAMD in UK Routine Clinical Practice (BESRA)

Neovascular Age-related Macular Degeneration

United Kingdom
Retina Vitreous Associates of Florida
Ocular Therapeutix, Inc.

Terminated

Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections (DETeR)

Diabetic Macular Edema | Retinal Vein Occlusion | Neovascular Age-related Macular Degeneration

United States
Asociación para Evitar la Ceguera en México

Completed

Short-term Effect of Intravitreal Dexamethasone Implant in Refractory Diabetic Macular Edema

Diabetic Macular Edema

Mexico
Bayer

Completed

Study to Gather Information on the Safety and Use of Aflibercept Injections Into the Eye for the Treatment of Eye Disorders in Mexican Routine Clinical Practice (MAIA)

Retinal Disease

Mexico
Cairo University

Terminated

Effect of Ranibizumab Versus Bevacizumab on the Macular Perfusion in Diabetic Macular Edema (REBEL)

Diabetic Retinopathy | Diabetic Macular Edema | Vascular Endothelial Growth Factor Overexpression | Macular Ischemia

Egypt
Aerie Pharmaceuticals

Completed

A Study Assessing AR-13503 Implant in Subjects With nAMD or DME

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections (MERLIN)

Age-Related Macular Degeneration

United States, Puerto Rico
Beijing Hospital

Completed

Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME

Diabetic Macular Edema

China
Beijing Hospital

Completed

Combination of Intravitreal Ranibizumab With or Without Macular Laser Photocoagulation for ME Secondary to BRVO

Branch Retinal Vein Occlusion | Ranibizumab | Laser Photocoagulation

China
Genentech, Inc.

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of FCFD4514S in Patients With Geographic Atrophy

Geographic Atrophy
Sandoz

Completed

Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Prefilled Syringe

Neovascular Age-related Macular Degeneration (nAMD)

United States

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