Search clinical trials for: human challenge study

Total 135885 results

M.D. Anderson Cancer Center

Not yet recruiting

Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)

Hormone Receptor-positive Human Epidermal Growth Factor 2-negative | Metastatic Invasive LObular Carcinoma

United States
Huashan Hospital
Chinese Academy of Sciences

Not yet recruiting

A Study of the Higher Cognitive Functions of the Human Brain With Single-neuron Activity Recording

Cognition

China
Oregon Health and Science University

Not yet recruiting

DBS TaT in Peer-assisted Telemedicine for Hepatitis C

Hepatitis C
Innovation Research & Training
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Study of an Online Program to Help Parents Talk With Their Tween Children About Health, Gender, Body-Image, and Relationships

Communication | Parent-Child Relations | Parenting

United States
CDR-Life AG

Recruiting

First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

Select Advanced Solid Tumors

United States, Denmark
Signati Medical Inc

Recruiting

A Safety Study in Human Subjects Evaluating the Use of the Signati System for Vasectomy

Vasectomy

United States
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Celgene
Bristol-Myers Squibb

Recruiting

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation (KarMMa-9)

Multiple Myeloma

Austria, United States, Spain, Australia, Japan, France, Israel, Italy, Canada, Greece, Belgium, Norway, Romania, Czechia, Denmark, Germany, Korea, Republic of, United Kingdom, Poland
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
Eli Lilly and Company

Not yet recruiting

A First-In-Human Study of LY3985297 in Healthy Participants

Healthy

United States
University of Kansas Medical Center

Not yet recruiting

Dry Needling in Multiple Sclerosis

Multiple Sclerosis | Spasticity

United States
The University of Texas Health Science Center,...
Brighter Bites and Humana Foundation

Not yet recruiting

Brighter Bites & University of Texas Physicians Produce Rx Extension: Evaluating the Effectiveness of a Prospective Clinical Nutrition Study With Produce Prescriptions

Obesity, Childhood

United States
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B
BioMarin Pharmaceutical

Not yet recruiting

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Idiopathic Short Stature
GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
HealthPartners Institute

Not yet recruiting

Hepatitis C Lab Testing Comparison Study

Hepatitis C
University Hospitals Cleveland Medical Center

Not yet recruiting

eHealth for Breastfeeding Support - the HOTSPOT Trial

Breast Feeding

United States
King Chulalongkorn Memorial Hospital
Health Systems Research Institute,Thailand

Recruiting

Investigating Neurocognitive Disorders Epidemiology (INDE)

Dementia | Alzheimer Disease | Cognitive Decline

Thailand
G.ST Antivirals GmbH

Recruiting

A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults

Acute Nasopharyngitis

Netherlands
EdiGene Inc.
The First Affiliated Hospital of Henan University of Science and Technology; Changping Laboratory

Recruiting

A Study to Evaluate the Safety and Efficacy of ATHENA CAR-T in Subjects With Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic

China
Memorial Sloan Kettering Cancer Center
Hookipa Biotech GmbH; Naveris

Recruiting

A Study of HB-202/HB-201 in People With Human Papilloma Virus 16-Positive Head and Neck Squamous Cell Cancer (HPV 16+ HNSCC)

HPV16+ Squamous Cell Carcinoma

United States
Wageningen University

Recruiting

The EXPLAIN Study: Exploring Plant-Based Meat Analogues for Their Impact on Health (EXPLAIN)

Blood Pressure | Cardiometabolic Health

Netherlands
bioLytical Laboratories

Not yet recruiting

A Study to Evaluate the Performance, Usability, and Result Interpretation of INSTI® HIV Self-Test

Human Immunodeficiency Virus I Infection | Human Immunodeficiency Virus II Infection
bioLytical Laboratories
St Vincent's Hospital Melbourne

Not yet recruiting

A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites

Hepatitis B | Hepatitis B Infection

Australia
Versa Vascular, Inc

Not yet recruiting

A First in Human Study for the Versa Device for Tricuspid Regurgitation

Tricuspid Regurgitation

New Zealand
Puma Biotechnology, Inc.

Not yet recruiting

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer (ALISCA-Breast1)

Metastatic Breast Cancer | Recurrent Breast Cancer | Hormone Receptor Positive HER-2 Negative Breast Cancer

United States
Chinese University of Hong Kong

Recruiting

SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus

Chronic Hepatitis B

Hong Kong
Wake Forest University Health Sciences
InnoTech Precision Medicine

Not yet recruiting

Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer

Oropharyngeal Squamous Cell Carcinoma | Human Papillomavirus Infection

United States
Octapharma

Recruiting

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema

Romania
Sanofi Pasteur, a Sanofi Company

Recruiting

A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above

Influenza Immunization

United States, Puerto Rico
Sengkang General Hospital
Singapore General Hospital; Duke-NUS Graduate Medical School; Lee Kong Chian...

Recruiting

Pilot Study of the Human Metagenome in Metabolic Diseases

Obesity | Metabolic Syndrome | Sarcopenia | Chronic Inflammation | Sarcopenic Obesity

Singapore
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Pavol Jozef Safarik University
University of Roma La Sapienza; Western University; L Pasteur University Hospital and other collaborators

Not yet recruiting

Complex Exploratory Study of Alcohol-Associated Hepatitis (CESAH)

Alcoholic Hepatitis

Slovakia
Beijing Friendship Hospital

Not yet recruiting

A Study on Factors of Biochemical Response in Autoimmune Hepatitis

Autoimmune Hepatitis

China
Divoluci

Not yet recruiting

Study Human Digital Support Transitional Care (SUNH-ST)

Aging

France
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study for Assessing the Efficacy and Safety ParActin® in Individuals With Upper Respiratory Tract Infections

Upper Respiratory Tract Infections

India
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute Ltd

Not yet recruiting

Covid-19 and Influenza Oral Vaccine Study

Influenza, Human | covid19 Infection

Australia
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Megalabs
Azidus Laboratories

Not yet recruiting

Comparative Study of Two Recombinant Human Erythropoietin Products on Chronic Kidney Disease Patients (ENCASE)

Anemia of Chronic Kidney Disease

Uruguay
Bayer

Recruiting

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Yale University
Department of Health and Human Services

Not yet recruiting

Project Women's Insomnia Sleep Health Equity Study (WISHES) (Project WISHES)

Insomnia | Cardiometabolic Health | Sleep Health

United States
University of Parma
Foundation for Liver Research; Azienda Ospedaliero-Universitaria di Parma; National... and other collaborators

Recruiting

Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols (PRE-CARE-DIET)

Obesity | Cardiometabolic Health | Individual Variability in (Poly)Phenol Metabolism | Personalized Dietary Intervention

Italy
UNC Lineberger Comprehensive Cancer Center
Bellicum Pharmaceuticals

Not yet recruiting

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

Breast Cancer | Triple Negative Breast Cancer | Relapse | Resistant Cancer

United States
Hyalex Orthopaedics, Inc.

Recruiting

The Hyalex First-in-Human Study

Cartilage Injury

Poland
Bayer

Not yet recruiting

A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer

Hepatocellular Carcinoma (HCC)

United States
NeuShen Therapeutics

Recruiting

First-into-human Study of NS-136 in Healthy Subjects

Healthy Subjects

Australia
IRCCS San Raffaele
Istituto Auxologico Italiano; Fondazione Policlinico Universitario Campus Bio-Medico

Recruiting

Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess. Cross-sectional and Prospective Study

Acromegaly | Bone Fracture

Italy
Synergia Medical

Not yet recruiting

A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl (AURORA)

Drug Resistant Epilepsy
IRCCS Multimedica

Recruiting

FAiling HearT in the Elderly (FATE) Study (FATE)

Heart Failure | Frailty

Italy
Guangdong Ruishun Biotech Co., Ltd
Changhai Hospital; Peking University People's Hospital; RenJi Hospital; The Affiliated...

Not yet recruiting

A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

China

Search clinical trials for: human challenge study

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