Search clinical trials for: intravitreal

Total 971 results

Kodiak Sciences Inc

Terminated

Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age-related Macular Degeneration

United States
Fondation Ophtalmologique Adolphe de Rothschild
Bayer

Active, not recruiting

Spontaneous Retinal Artery Pulses (SPARs) as a Prognostic Determinant of Central Retinal Vein Occlusions (CRVO) in Patients With or Without Intravitreal Aflibercept Injections (PULSOV)

Central Retinal Vein Occlusion

France
Shanghai Eye Disease Prevention and Treatment Center

Enrolling by invitation

Vitrectomy Combined With Intravitreal Dexamethasone Implant for Idiopathic Epiretinal Membrane With Macular Oedema

Epiretinal Membrane

China
Althaia Xarxa Assistencial Universitària de Manresa
University of Vic - Central University of Catalonia

Completed

Effect of Music Therapy on the Anxiety Level of Patients During the Administration of Ocular Intravitreal Injections

Anxiety and Fear

Spain
Novartis Pharmaceuticals

Completed

A Study of the Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KITE)

Diabetic Macular Edema

Czechia, India, Russian Federation, Taiwan, Turkey, Lebanon, Denmark, Estonia, France, Germany, Hungary, Korea, Republic of, Latvia, Lithuania, Bulgaria, Norway, Belgium, Malaysia, Sweden, Slovakia, Singapore, Poland, Switzerland
ONL Therapeutics

Completed

A Phase 2 Study to Assess the Safety and Efficacy of Intravitreal ONL1204 Ophthalmic Solution in Subjects With Mac-off Retinal Detachment

Rhegmatogenous Retinal Detachment - Macula Off

United States
IVERIC bio, Inc.

Completed

A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)

Macular Degeneration | Geographic Atrophy

United States, Spain, France, Germany, Austria, Belgium, Israel, Poland, Canada, Italy, Estonia, Australia, United Kingdom, Hungary, Argentina, Brazil, Colombia, Croatia, Czechia, Latvia
Ophthotech Corporation

Terminated

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy

Age-Related Macular Degeneration

Israel, United States, Germany, Denmark, France, Turkey, Hungary, Colombia, Australia, Argentina, Spain
Ophthotech Corporation

Terminated

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy

Age-Related Macular Degeneration

Italy, Canada, Switzerland, United States, United Kingdom, Austria, Belgium, Brazil, Czechia, Estonia, Latvia, Poland, Slovakia
Fondation Ophtalmologique Adolphe de Rothschild

Suspended

Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease (COATS-VEGF)

Retinal Telangiectasis | Coats Disease

France
Oxular Limited

Active, not recruiting

Suprachoroidal Sustained-Release OXU-001 Compared to Intravitreal Ozurdex® in the Treatment of Diabetic Macular Edema (OXEYE)

Diabetic Macular Edema

United States, Puerto Rico
Wills Eye

Completed

Pain Reduction With Topical Bromfenac Versus Artificial Tear After Intravitreal Injection.

Pain | Pain, Acute | Intravitreal Injection

United States, Canada
Institut Curie
Fondation Rothschild Paris

Active, not recruiting

Conservative Treatments of Retinoblastoma (RETINO2011)

Children | Retinoblastoma | Retinal Neoplasm

France
Anders Kvanta

Completed

Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy

Proliferative Diabetic Retinopathy

Sweden
GenSight Biologics

Completed

RESCUE and REVERSE Long-term Follow-up (RESTORE)

Leber Hereditary Optic Neuropathy

United States, France, Italy, United Kingdom, Germany
Cairo University

Completed

Intravitreal Infliximab for Proliferative Vitreoretinopathy (FIXER)

Rhegmatogenous Retinal Detachment | Retinal Detachment | Proliferative Vitreoretinopathy

Egypt
GenSight Biologics

No longer available

EAP_GS010_single Patient

Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
Massachusetts General Hospital
Center for Survey Research, University of Massachusetts, Boston

Completed

Online Trial Examining Validity of the Shared Decision Making Process Survey With Video Vignettes

Colorectal Cancer | High Cholesterol

United States
University of Oklahoma

Completed

Aflibercept Injection for Proliferative Diabetic Retinopathy

Vitreous Hemorrhage

United States
RemeGen Co., Ltd.

Completed

Evaluation of RC28-E Injection in Diabetic Macular Edema

Diabetic Macular Edema

China
University of California, Davis

Active, not recruiting

Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy

Diabetic Retinopathy | Retinitis Pigmentosa | Non-exudative Age-related Macular Degeneration | Retina Vein Occlusion | Hereditary Macular Degeneration

United States
Egyptian Biomedical Research Network

Completed

Subfoveal Choroidal Thickness and Visual Acuity After Intravitreal Injection of Ranibizumab in Diabetic Retinopathy

Diabetic Retinopathy | Visual Acuity | Ranibizumab | Subfoveal Choroidal Thickness | Intravitreal

Egypt
Nanoscope Therapeutics Inc.

Enrolling by invitation

Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study (REMAIN)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies

United States, Puerto Rico
Kim's Eye Hospital

Completed

Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCV

Age-Related Macular Degeneration | Choroidal Neovascularization | Polypoidal Choroidal Vasculopathy

Korea, Republic of
University of Oklahoma

Completed

The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection

Dry Eye | Dry Eye Syndromes | Ocular Surface Disease

United States
Santen Inc.

Terminated

LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye

Non Infectious Uveitis

United States, India, Italy, Argentina
Bayer
Regeneron Pharmaceuticals

Completed

Intravitreal Aflibercept Injection in Vision Impairment Due to DME (VIVID-DME)

Diabetes Mellitus | Macular Edema

France, Japan, Australia, Austria, Poland, Czechia, Denmark, Germany, Hungary, Italy, Spain
Bo Jia

Completed

Influence of Intravitreal Aqueous Tamponade on Lens Status and Ocular

Cataract | Aqueous Tamponade

China
Nanoscope Therapeutics Inc.

Completed

Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt Disease (STARLIGHT)

Stargardt Disease

United States
Bayer
Regeneron Pharmaceuticals

Completed

Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye (ARIES)

Macular Degeneration

Spain, Hungary, United Kingdom, Australia, Italy, Canada, France, Germany
Bayer
Regeneron Pharmaceuticals

Completed

Routine Clinical Practice for Use of Intravitreal Aflibercept Treatment in Patients With Diabetic Macular Edema (APOLLON)

Diabetic Retinopathy

France
Ospedale Santa Croce-Carle Cuneo

Completed

M Charts Versus Amsler Test in Evaluating Metamorphopsia in nAMD (MVAinAMD2022)

Metamorphopsia | Macular Degeneration, Wet

Italy
Stanford University
Santen Inc.

Withdrawn

Intravitreal Sirolimus as Therapeutic Approach to Uveitis (SAVE-2)

Panuveitis | Uveitis | Posterior Uveitis | Intermediate Uveitis

United States
American Genomics, LLC

Completed

A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population

Anesthesia, Local

United States
Assiut University

Active, not recruiting

Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients With Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF Injection

Macular Edema | Retinal Vein Occlusion

Egypt
Larkin Community Hospital

Completed

Role of Intravitreal Aflibercept Injection for the Treatment of Radiation Maculopathy

Adverse Effect of Radiation Therapy
Imperial College London

Withdrawn

Combined Ranibizumab and Iluvien for Diabetic Macular Oedema (CASSIE)

Diabetes | Diabetic Macular Edema
European School of Advanced Studies in Ophthalmology

Completed

Diabetic Macular Edema: Relevance of Staging Progression on Therapeutic Outcome

Diabetic Macular Edema

Switzerland
jCyte, Inc
California Institute for Regenerative Medicine (CIRM)

Completed

Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa

Retinitis Pigmentosa

United States
East Kent Hospitals University NHS Foundation Trust

Completed

Retinal Oximtery Following Treatment for Diabetic Maculopathy

Diabetic Maculopathy
Hoffmann-La Roche

Active, not recruiting

A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm (PAVILION)

Diabetic Retinopathy

United States, Puerto Rico
David L Rogers, MD

Active, not recruiting

Intravitreal ERT to Prevent Retinal Disease Progression in Children With CLN2

Neuronal Ceroid Lipofuscinosis Type 2

United States
EyePoint Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert (FAI)

Uveitis | Uveitis, Posterior | Uveitis, Intermediate

United States
University of Nebraska
Regeneron Pharmaceuticals

Completed

Pharmacokinetic Study of Intravitreal Aflibercept Injection in Eyes With Wet Age-related Macular Degeneration (DRAW)

Neovascular Macular Degeneration

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Evaluation of Adherent Invasive E. Coli Eradication in Adult Crohn Disease (TEOREM)

Crohn Disease | Adherent-invasive E. Coli

France
Greater Houston Retina Research
Regeneron Pharmaceuticals; Clinical Trials Resource Group, LLC

Active, not recruiting

Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial (VOYAGE)

Diabetic Retinopathy

United States, Puerto Rico
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for DME (INFINITY)

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
Adverum Biotechnologies, Inc.

Completed

ADVM-022 Intravitreal Gene Therapy for Wet AMD (OPTIC)

Neovascular Age-related Macular Degeneration | Wet Age-related Macular Degeneration

United States
Nanoscope Therapeutics Inc.

Enrolling by invitation

A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal Injection (EXTEND)

Retinal Degeneration | Retinitis Pigmentosa | Retinal Disease

India
jCyte, Inc
California Institute for Regenerative Medicine (CIRM)

Completed

Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis Pigmentosa

Retinitis Pigmentosa

United States

Search clinical trials for: intravitreal

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