Search clinical trials for: pre-exposure immunization

Total 825 results

University of Alabama at Birmingham
Tesaro, Inc.; Susan G. Komen Breast Cancer Foundation; Translational Breast Cancer... and other collaborators

Recruiting

Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer

Metastatic Breast Cancer | HER2 Positive Breast Carcinoma

United States
Johns Hopkins University

Recruiting

Influenza Immunization in Adults Over Age 75

Influenza | Older Adults | Immunization | Over Age 75

United States
Canadian Paediatric Society

Recruiting

Canadian Rotavirus Surveillance Through the Immunization Monitoring Program Active (IMPACT)

Viral Gastroenteritis Due to Rotavirus

Canada
Sri Edupuganti
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Turnover of Antigen Specific Lymphocytes and Monocytes After Immunization With the 17D Yellow Fever Vaccine

Yellow Fever

United States
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Active, not recruiting

A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor Cells (CHESAT)

Neuroblastoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines

Influenza | Healthy Volunteers

United States
University of California, San Francisco
National Institute of Mental Health (NIMH); Santa Casa Medical School

Active, not recruiting

Reducing Intersectional Stigma Among High-Risk Women in Brazil to Promote Uptake of HIV Testing and PrEP (PRISM Brazil)

HIV Prevention

Brazil
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Durham Connects RCT Evaluation

Unspecified Child Maltreatment, Suspected | Unspecified Child Maltreatment, Confirmed

United States
Columbia University
Yale University; Fogarty International Center of the National Institute of...

Active, not recruiting

Pre-exposure Prophylaxis Implementation in Central-Eastern European Countries

Human Immunodeficiency Virus

United States, Romania
Diskapi Teaching and Research Hospital

Completed

Anterior Cutaneus Nerve and Distal Adductor Canal Block With USG for Total Knee Replacement Analgesia

Knee Replacement Arthroplasty | Nerve Block | Pain Measurement

Turkey
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Xenogeneic HER2/Neu DNA Immunization for Patients With Metastatic and High Risk Breast Cancer: A Phase I Study to Assess Safety and Immunogenicity

Breast Cancer

United States
Sinovac Research and Development Co., Ltd.

Completed

Immunogenicity and Safety of Booster Immunization of COVID-19 Vaccine (Vero Cell), Inactivated (Omicron Variant) in Healthy People Aged 18 Years and Above

COVID-19

China
Sanofi Pasteur, a Sanofi Company

Completed

Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.

Influenza Immunization

United States, Poland, Spain, Czechia
BioNTech SE

Active, not recruiting

Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

Malaria

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older

Influenza Immunization

Australia, United States, Puerto Rico
Sanofi Pasteur, a Sanofi Company

Completed

Substudy 01 - Safety and Immunogenicity of One Monovalent Modified mRNA Vaccine Encoding Influenza Hemagglutinin With LNP, in Adult Participants Aged 18 to 49 Years and 60 Years and Above

Influenza Immunization

Australia, United Kingdom
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older

Respiratory Syncytial Virus Immunization

United States, Australia, Puerto Rico
Galderma R&D

Completed

A Study to Assess Immunization Responses in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Treated With Nemolizumab

Dermatitis, Atopic

United States
University of North Carolina, Chapel Hill
Gilead Sciences

Completed

Study for IFE4PrEP Intervention on PrEP Uptake by Southern African American Women (IFE4PrEP)

HIV Prevention

United States
Aga Khan University

Completed

Community Engagement and Conditional Incentives to Accelerate Polio (GLIDE)

Polio | Incentives | Immunization; Infection

Pakistan
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older

Influenza Immunization

United States, Puerto Rico
Tatyana Zubkova

Completed

Evaluation of RSV/Flu-01E Vaccine for the Prevention of RSV Infection in Volunteers Aged 18 to 59 Years and Over 60 Years

Respiratory Syncytial Virus Infections

Russian Federation
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
Aerospace Center Hospital

Completed

Different Dose of Esketamine Inhibiting Response to Laryngeal Mask Airway Insertion

Anesthesia

China
University of Washington
National Institute on Drug Abuse (NIDA); Makerere University

Active, not recruiting

Uganda PrEP and Harm Reduction Evaluation

HIV-1-infection

Uganda
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5407 in Adult Participants18 Years of Age and Older

Influenza Immunization

Puerto Rico, United States
VA Office of Research and Development
Mayo Clinic

Completed

Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19

Coronavirus Disease 2019 (COVID-19)

United States
Sanofi Pasteur, a Sanofi Company
AstraZeneca

Active, not recruiting

Study of a Single Intramuscular Dose of Nirsevimab in the Prevention of Hospitalizations Due to Respiratory Syncytial Virus (RSV) Infection in Healthy Term and Preterm Infants During the First Year of Life (VAS00006)

Healthy Volunteer | RSV Immunization

France, Germany, United Kingdom
Harvard Pilgrim Health Care
National Institute of Mental Health (NIMH); Beth Israel Deaconess Medical Center and other collaborators

Active, not recruiting

Clinical Decision Support for PrEP (PrEDICT)

HIV Infections | Preexposure Prophylaxis (PrEP)

United States
GlaxoSmithKline

Completed

A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers

Diphtheria

Spain, Germany, Italy
Assistance Publique - Hôpitaux de Paris

Terminated

Quaternary Ammonium and Immunization in Hairdressers (AQTIFF)

Hypersensitivity | Quaternary Ammonium

France
Michael A. Thompson, MD, PhD
Vince Lombardi Cancer Clinic

Withdrawn

B-Cell Hematologic Malignancy Vaccination Registry (HMvax-Regist)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Waldenstrom Macroglobulinemia | Monoclonal Gammopathy of Undetermined Significance | Hematological Malignancies | B-Cell Chronic Lymphocytic Leukemia | Lymphocytosis

United States
University of Washington
Frankel Family Foundation; Stewardship Foundation

Active, not recruiting

Leading Advancements in the Uptake of Newborn Community Health (LAUNCH)

Breastfeeding, Exclusive | Immunization; Infection | Growth; Stunting, Nutritional

Ethiopia
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

Pharmacy Delivery to Expand the Reach of PrEP in Kenya

HIV Prevention

Kenya
Changchun Zhuoyi Biological Co., Ltd

Completed

Vaccine Prevention of Rabies Adopts 4-shot Immunization Method

Rabies Human | Antibody Titer

China
Changchun Zhuoyi Biological Co., Ltd

Enrolling by invitation

Prevention of Rabies With Four Doses of Rabies Vaccine

Rabies Human | Antibody

China
National Institute of Allergy and Infectious Diseases...

Suspended

Evaluating the Live-Attenuated Human Parainfluenza Virus Type 3 Vectored Vaccine Candidate Expressing Ebolavirus Zaire Glycoprotein as the Sole Envelope Glycoprotein

Ebola Virus Disease

United States
The University of Texas Medical Branch, Galveston
Cancer Prevention Research Institute of Texas

Active, not recruiting

GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose

Efficacy | Human Papilloma Virus | Immunization

United States
Zhuhai Trinomab Pharmaceutical Co., Ltd.

Completed

Study to Compare the Efficacy and Safety of Passive Immunization With TNM002 Injection and Human Tetanus Immunoglobulin as Prophylaxis Against Tetanus

Tetanus

China
University Hospital, Bordeaux

Completed

Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS) (TAAS)

Glanzmann Thrombasthenia

France
University of British Columbia
Canadian Institutes of Health Research (CIHR); University of Calgary; Alberta... and other collaborators

Completed

CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study

Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Canada
Hacettepe University

Completed

Hacettepe University COVID-19 Vaccinated's Health Cohort- Students of Health Sciences (HU-CoVaCS)

SARS-CoV2 Infection | COVID-19 Pandemic | Health | Immunization; Infection

Turkey
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States
Canadian Immunization Research Network
Massachusetts General Hospital; CHU de Quebec-Universite Laval; McGill University... and other collaborators

Active, not recruiting

Mix and Match of the COVID-19 Vaccine for Safety and Immunogenicity (MOSAIC)

COVID-19

Canada
GlaxoSmithKline

Completed

Impact of Boostrix™ Maternal Vaccination on Morbidity and Mortality of Pertussis Disease in Infants ≤6 Weeks of Age, in Bogota, Colombia.

Tetanus | Diphtheria | Acellular Pertussis | Diphtheria-Tetanus-acellular Pertussis Vaccines | Aspergillosis, Allergic Bronchopulmonary

Colombia
Butantan Institute

Completed

Safety and Immunogenicity of the Butantan Institute Influenza Vaccine Compared to Sanofi Pasteur Influenza Vaccine

Influenza

Brazil
Johns Hopkins Bloomberg School of Public Health
United States Department of Defense; Naval Medical Research Center

Active, not recruiting

CampETEC Hyperimmune Bovine Colostrum (HBC)

Healthy Volunteer

United States
Central Hospital, Nancy, France

Completed

Influenza and Pertussis Vaccination Status of Women in Immediate Postpartum and Caregivers (COVAGRIP)

Influenza Viral Infections | Pertussis/Whooping Cough

France
Cecile Tremblay
Merck Sharp & Dohme LLC; Dalhousie University; Université de Montréal; Coalition... and other collaborators

Active, not recruiting

African-Canadian Study of HIV-Infected Adults and a Vaccine for Ebola - ACHIV-Ebola

Ebola

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Prometheus Laboratories; Key Biologics, LLC; Adelson...

Active, not recruiting

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

Melanoma

United States

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