Search clinical trials for: preservative

Total 198 results

Case Comprehensive Cancer Center

Withdrawn

Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction

Breast Cancer
Alexandria University

Completed

Preservative-free Tafluprost Eye Drops in Newly Diagnosed Patients With Glaucoma

Glaucoma

Egypt
Peregrine Eye and Laser Institute

Completed

Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin

Cataract Senile | Endophthalmitis | Antibiotic Side Effect | Safety Issues

Philippines
Tanta University

Unknown

Hydroxychloroquine and Nitazoxanide Combination Therapy for COVID-19

COVID-19
Laboratorios Sophia S.A de C.V.

Completed

Safety and Tolerability of the Preservative-free Ophthalmic Solution PRO-122 Compared With Krytantek Ofteno® (PRO-122/I)

Glaucoma

Mexico
Hospital for Special Surgery, New York

Completed

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery. (LMA vs Spinal)

Pain | Spinal Anesthesia | Postoperative Nausea and Vomiting | General Anesthesia | Nerve Block

United States
Laboratorios Sophia S.A de C.V.

Completed

Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV) (087LATAMFIV)

Dry Eye Syndrome

Mexico
Chang Gung Memorial Hospital

Unknown

Effect of Preservative-free Low-dose Hyaluronic Acid-containing Salt Solution on Dry Eye Disease

Dry Eye

Taiwan
Laboratorios Sophia S.A de C.V.

Completed

Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects (PRO-087/I)

Dry Eye Syndromes | Lubricant Allergy | Tear Disorder

Mexico
Novo Nordisk A/S

Completed

Comparing Efficacy and Safety of Thrice Daily Versus Twice Daily NovoMix® 30 (Biphasic Insulin Aspart 30) in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin

Diabetes | Type 2 Diabetes Mellitus

Taiwan, Turkey, India, Algeria, Hong Kong, China, Ukraine
GlaxoSmithKline

Completed

Immuno & Safety Study of GSK Biologicals' Thio or Preservative Free Hepatitis B Vaccine in Subjects Aged 11-15 Yrs

Hepatitis B

Belgium, Ukraine, Australia
Allergan

Completed

Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease

Dry Eye Syndromes

United States
Wills Eye
University of Medicine and Dentistry of New Jersey

Terminated

Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol

Sturge Weber Syndrome | Port-wine Mark

United States
University of Saskatchewan

Completed

Ropivacaine vs Lidocaine in the Endotracheal Tube Cuff on Post-Operative Sore Throat

Pharyngitis | Intubation, Intratracheal | Lidocaine | Ropivacaine | Post-operative Sore Throat

Canada
Alcon Research

Completed

Clinical Evaluation of the Safety and Efficacy of FID 120947A

Refractive Error

Japan
University of Alabama at Birmingham
Oculus Innovative Sciences, Inc.

Completed

Pressure Ulcer Healing With Microcyn

Spinal Cord Injuries | Pressure Ulcer

United States
Merck Sharp & Dohme LLC

Completed

Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

Ocular Hypertension | Glaucoma
Wake Forest University
EKR Therapeutics, Inc

Terminated

Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing

Hip Arthroplasty

United States
Wake Forest University
National Institute of General Medical Sciences (NIGMS)

Terminated

Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement

Hip Arthroplasty

United States
GlaxoSmithKline

Completed

A Study to Compare the Immunogenicity of GSK Biologicals' 10Pn-PD-DiT 4-dose Presentation to the Licensed 1-dose Synflorix™ (10Pn-PD-DiT) Vaccine When Co-administered With DTPw-combination Vaccine in Healthy Infants

Infections, Streptococcal

Bangladesh
Peter A Knight

Completed

Parasternal Nerve Block in Cardiac Patients

Coronary Artery Disease | Pain, Postoperative

United States
Santen Oy

Completed

A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United Kingdom, United States
Icahn School of Medicine at Mount Sinai

Completed

Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?

Cesarean Section | Spinal Anesthesia

United States
Ordination Dr. Hommer

Completed

A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thickness

Ocular Hypertension | Glaucoma, Open-Angle

Austria
Novartis

Completed

Efficacy and Tolerability of Carbamazepine CR in Diabetic Neuropathy Pain

Neuropathic Pain

Morocco
Northwestern University

Completed

Ultrasound-guided Adductor Canal Block for Total Knee Replacement

Knee Injuries | Complications; Arthroplasty

United States
Merck Sharp & Dohme LLC

Completed

Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)

Ocular Hypertension | Open-angle Glaucoma
Xiangya Hospital of Central South University

Completed

The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass (ERAS)

Valvular Heart Disease

China
Marc Tewfik

Completed

Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery

Chronic Sinusitis

Canada
Northwestern University

Terminated

Analgesic Benefits of Genicular Nerve Blocks of the Posterior Knee for Patients Undergoing ACL Reconstruction

Rupture of Anterior Cruciate Ligament

United States
Cambridge Health Alliance
Northwestern University

Completed

A Double-Blind, Placebo-Controlled Study of Galantamine to Improve Cognitive Dysfunction in Bipolar Disorder

Bipolar Disorder

United States
Gangnam Severance Hospital

Completed

Efficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma Patients

Primary Open-angle Glaucoma
Gina Rogers

Withdrawn

Tears Substitutions and Their Effects on Higher Order Aberrometery

Dry Eye Syndrome

United States
GlaxoSmithKline

Completed

Investigational Parkinson's Disease In Patients Not Well Controlled On L-dopa

Parkinson Disease

United States, France, Spain, Poland, Belgium, Hungary, Germany, Italy, Czech Republic
Novo Nordisk A/S

Completed

Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin (SIT2MIX)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of, India, Malaysia, Turkey, Argentina, Greece, Australia, Portugal, Thailand, Brazil
SIFI SpA

Completed

Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects

Acanthamoeba Keratitis
Peking University People's Hospital
The First Affiliated Hospital of Anhui Medical University; Guangdong Provincial... and other collaborators

Unknown

A Prospective Multi-Center Research on Bowel Dysfunction After Sphincter Preservative Surgery (PMCRBDSPS)

Rectal Cancer | Bowel Dysfunction
Sanofi Pasteur, a Sanofi Company

Completed

Study of Fluzone® Quadrivalent, Fluzone® Intradermal Quadrivalent, and Fluzone® High-Dose, Influenza Vaccines in Adults

Influenza

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of the 2015-2016 Formulation of Fluzone® Quadrivalent (Influenza Vaccine) Among Healthy Children

Influenza

United States
Beijing Children's Hospital

Unknown

Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism

Kallmann Syndrome | Hypogonadotropic Hypogonadism

China
Epstein, Arthur B., OD, FAAO
Alcon Research

Completed

Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses

Keratitis

United States
University of Colorado, Denver

Completed

Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure

Ocular Hypertension | Open Angle Glaucoma

United States
Universitaire Ziekenhuizen KU Leuven
Allergan

Unknown

Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/ml (SPORTII)

Ocular Hypertension | Glaucoma

Belgium, Austria, Italy, Switzerland, United Kingdom
Niğde State Hospital

Completed

Comparison of Autologous Serum Versus Preservative Free Artificial Tear

Dry Eye

Turkey
Duke University

Completed

Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery

Strabismus

United States
Sanofi Pasteur, a Sanofi Company

Completed

Annual Study for Serum Collection for Immunogenicity and Safety Evaluation in Healthy Children Receiving Fluzone®

Influenza | Orthomyxoviridae Infections

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity Testing of Influenza Vaccine in Healthy Children 2 Months and 6 Months of Age

Influenza

United States
Colgate Palmolive

Completed

Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)

Gingivitis | Dental Plaque

United States
Alcon Research

Completed

Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects

Dry Eye
George Macrinici
Associated Anesthesiologists of Joliet; Statking Consulting, Inc.

Completed

Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA (ACB)

Arthroplasty, Replacement, Knee | Nerve Block

United States

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