Search clinical trials for: AMG 531

Total 1939 results

SCRI Development Innovations, LLC
Amgen

Completed

Carboplatin, Pemetrexed, and Panitumumab in Patients With Advanced Non-Squamous K-ras Wild Type NSCLC

Non-Small-Cell Lung Cancer

United States
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Research Study To Test How Filgrastim Hospira Works In The Body Of Healthy Study Subjects When Given By Subcutaneous Injection (Shot) Compared To An Already U.S.-Approved Drug Neupogen® (Amgen)

Neutropenia (Low White Blood Cell Count)

United States
Ohio State University Comprehensive Cancer Center
Amgen

Completed

Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL)

Hematopoietic/Lymphoid Cancer | Recurrent Small Lymphocytic Lymphoma | B-cell Chronic Lymphocytic Leukemia | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia

United States
Amgen

Terminated

Study to Evaluate the Safety, Tolerability, and Action of AMG 357 in Females With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Novartis
Amgen

Terminated

A Study Conducted in Subjects With Relapsed/Refractory Multiple Myeloma (MM); to Determine Dose of Afuresertib in Combination With Carfilzomib (Part 1) and to Investigate the Safety, Pharmacokinetic and Clinical Activity of the Combination Compared With Carfilzomib Alone (Part 2)

Cancer

United States
Pharmaxis

Completed

Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis

Bronchiectasis

United States, United Kingdom, Australia, New Zealand, Argentina, Belgium, Chile, Germany, Netherlands
Technical University of Munich

Completed

Comparison of AMG and EMG to Avoid Residual Paralysis After General Anesthesia (CAMEM)

Anaesthesia | Respiratory Paralysis | Observation of Neuromuscular Block

Germany
Amgen

Completed

AMG 595 First-in-Human in Recurrent Gliomas

Glioblastoma Multiforme | Advanced Malignant Glioma | Anaplastic Astrocytomas

United States, Australia
Amgen

Completed

Effect of Panitumumab on the Pharmacokinetics of Irinotecan

Metastatic Colorectal Cancer

Canada, United States
Amgen

Completed

A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer

Advanced Hepatocellular Carcinoma | Inoperable Hepatocellular Carcinoma
Amgen

Terminated

A Phase 3 Study of Rilotumumab (AMG 102) With Cisplatin and Capecitabine (CX) as First-line Therapy in Gastric Cancer (RILOMET-2)

Gastric Cancer

Korea, Republic of, Japan
Amgen

Completed

AMG 172 First in Human Study in Patients With Kidney Cancer

Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | Clear Cell Renal Carcinoma | Renal Cell Adenocarcinoma

France, United States, Germany
Amgen

Completed

Study to Evaluate Motesanib With or Without Carboplatin/Paclitaxel or Panitumumab in the Treatment of Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | Lung Cancer
Amgen

Completed

AMG 853 Phase 2 Study in Subjects With Inadequately Controlled Asthma

Asthma
Amgen

Completed

AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib

Advanced Renal Cell Carcinoma
Amgen

Completed

Phase II Study to Evaluate the Efficacy of AMG 317

Asthma
Bayer
Amgen

Completed

Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006)

Carcinoma

United States
The Methodist Hospital Research Institute
Bayer; Amgen

Completed

Safety and Toxicity Study of Sorafenib in Patients With Kidney Cancer

Carcinoma, Renal Cell

United States
Amgen

Completed

Study to Assess Fixed Dosing of AMG 223 in Subjects With Chronic Kidney Disease on Hemodialysis With Hyperphosphatemia

End Stage Renal Disease | Chronic Kidney Disease | Kidney Disease | Hyperphosphatemic
Midnight Pharma, LLC

Completed

Almorexant (ACT 078573) in Adult Subjects With Chronic Primary Insomnia (RESTORA 1)

Primary Insomnia

Spain, Germany, Belgium, France, United Kingdom, Australia, Austria, Bulgaria, Czech Republic, Denmark, Finland, Hungary, Israel, Italy, Poland, Slovakia, South Africa, Sweden, Switzerland, Ukraine
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Amgen

Completed

Panitumumab, Docetaxel, Cisplatin, Radiation Therapy, and Surgery in Treating Patients With Newly Diagnosed, Locally Advanced Esophageal Cancer or Cancer of the Gastroesophageal Junction

Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Amgen

Completed

Observational Study of Correction of Anaemia With Darbepoetin Alfa at QM Dosing Interval in Patients With CKD Not on Dialysis (ADAPTATION)

Anaemia | Chronic Kidney Disease (CKD)

Austria, Hungary, Spain, Bulgaria, Poland, Greece, Czech Republic, Italy
Amgen

Completed

Multiple Ascending Dose Study on Safety, Tolerability, and Pharmacokinetics of AMG 581 in Healthy Subjects or Subjects With Schizophrenia or Schizoaffective (MAD)

Schizophrenia or Schizoaffective Disorder

United States
Amgen

No longer available

Expanded Access Protocol of Talimogene Laherparepvec for Subjects With Unresected, Stage lllB to IVM1c Melanoma

Unresected Stage IIIb to IVM1c Melanoma

United States
Amgen

Completed

Phase 1/1b Study of Rilotumumab in Japanese Subjects With Advanced Solid Tumors or Advanced or Metastatic Gastric or GEJ

Part 1- Advanced Solid Tumors | Part 2- Advanced or Metastatic Gastric Cancer | Part 2- Advanced or Metastatic GEJ

Japan
Indiana University School of Medicine
Amgen

Completed

Phase I Study of Gemcitabine, Sorafenib and Radiotherapy in Patients With Unresectable Pancreatic Cancer

Pancreatic Cancer | Adenocarcinoma of the Pancreas

United States
Amgen

Completed

Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy (STEPP)

Metastatic Colorectal Cancer | Colorectal Cancer | Colon Cancer | Skin Rash | Skin Toxicities
Nantes University Hospital

Completed

Multicentric Open-label Study of Switch From Abacavir/Lamivudine Fixed Dose Combination Plus Nevirapine to Abacavir/Lamivudine/Dolutegravir in Virologically Suppressed HIV-1 Infected Adults (SWAD) (SWAD)

HIV-1 Infection

France
Amgen

Completed

Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on Dialysis

Renal Impairment

United States
German Breast Group
Bristol-Myers Squibb; Pharmacia; Amgen

Completed

Preoperative Epirubicin Paclitaxel Aranesp Study (PREPARE)

Breast Cancer
Amgen

Completed

Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment (PRECEPT)

Cancer | Metastatic Colorectal Cancer | Colorectal Cancer | Rectal Cancer | Metastatic Cancer | Colon Cancer | Oncology
Memorial Sloan Kettering Cancer Center
Amgen

Terminated

Study of Gemcitabine, Carboplatin, and Panitumumab (GCaP) as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer

Bladder Cancer

United States
Amgen

Terminated

First-Line Treatment for Locally Advanced or Metastatic Mesenchymal Epithelial Transition Factor (MET) - Positive Gastric, Lower Esophageal, or Gastroesophageal Junction (GEJ) Adenocarcinoma (RILOMET-1)

Gastric Cancer

United States, Italy, Belgium, Hungary, Poland, Romania, Denmark, Switzerland, Canada, France, Germany, Russian Federation, Turkey, United Kingdom, Spain, Austria, Portugal, Australia, Greece, South Africa, Bulgaria, Ukraine, Brazil, ... and more
BioVex Limited
Amgen

Terminated

Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Carcinoma

United States, United Kingdom
Amgen

Completed

Study of Haemodialysis Patients Switching From Aranesp to Biosimilar (SHADE)

Anaemia

Australia, Italy, Poland, Germany, Greece, Bulgaria, Spain
Amgen

Completed

Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab

Metastatic Colorectal Cancer
Amgen

Completed

AMG 714 20060349 Multiple Dose Study in Moderate to Severe Psoriasis Subjects

Psoriasis
Pfizer
Amgen

Completed

Open-Label Study Comparing Etanercept to Conventional Disease Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

Chile, Colombia, Argentina, Mexico, Panama
Amgen

Completed

A Phase 1b/2 Study of AMG 655 in Combination With Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer
Translational Research in Oncology

Terminated

Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer

Ovarian Neoplasms

United States, France, Germany, Israel, Ireland, Spain, Canada, United Kingdom
Translational Research in Oncology

Completed

Study of AMG 479 as Second Line Therapy in Patients With Recurrent Platinum-sensitive Ovarian Cancer

Ovarian Neoplasms

United States, France, Ireland, Germany, Israel, Canada, Spain
University of Pittsburgh
Amgen

Withdrawn

Trial of Radiotherapy and Panitumumab in Salivary Gland Malignancies

Adenoma, Pleomorphic | Mixed Salivary Gland Tumor | Salivary Gland Tumor, Mixed | Syringoma, Chondroid

United States
Memorial Sloan Kettering Cancer Center
Pfizer; Amgen

Completed

Dose-Dense Epirubicin and Cyclophosphamide (EC) Followed by Paclitaxel in Breast Cancer: Feasibility

Breast Cancer | Adenocarcinoma of the Breast

United States
Amgen

Completed

Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk (AMG145)

Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events

Japan
Amgen

Completed

Study of Patients With ITP Estimating the Proportion Administering Romiplostim Correctly After Receiving Home Administration Training

Immune Thrombocytopenic Purpura

Spain, Austria, Belgium, Greece, United Kingdom, France, Germany, Netherlands
Pennington Biomedical Research Center
Amgen

Completed

The Effect of Leptin A-200, Caffeine/Ephedrine and Their Combination Upon Weight Loss and Body Composition in Man

Obesity

United States
University Hospital Inselspital, Berne

Completed

Peg-Granulocyte-Colony Stimulating Factor (GCSF) for Coronary Collateral Growth in Coronary Artery Disease Patients

Coronary Artery Disease

Switzerland
Takeda

Terminated

Study of Motesanib (AMG 706) in Combination With Paclitaxel and Carboplatin for Advanced Non-Squamous Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
Katy Peters
Amgen

Completed

AMG 102 and Avastin for Recurrent Malignant Glioma

Glioblastoma Multiforme | Gliosarcoma

United States
University of Aarhus
Amgen

Terminated

Effect of Darbepoetin Alfa (Aranesp®) on Anemia in Patients With Advanced Hormone Independent Prostate Cancer

Prostatic Neoplasms | Anemia

Denmark

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