Search clinical trials for: Randomized controlled trail

Total 16490 results

Universita degli Studi di Catania

Completed

Antibiotic Therapy is Not Necessary to Implant Totally Implantable Venous Access Devices: Randomized Prospective Study (TIVAD)

Infections
Hospital de Clinicas de Porto Alegre
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Changes in Oral Vitamin K Intake for Optimization of Chronic Oral Anticoagulation: A Randomized Trial

Blood Coagulation Disorders

Brazil
University of California, San Francisco

Completed

Pilot Study on the Effect of Oral Controlled-Release Alpha-Lipoic Acid on Oxidative Stress in Adolescents With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
Pfizer

Completed

A Multi-Center, Randomized, Double-Blind, Parallel Group Study To Compare The Efficacy And Tolerability Of Valdecoxib And Diclofenac In Patients With A Sprained Ankle

Pain | Sprains and Strains | Sprain

Chile, Mexico, Argentina, Colombia, Peru
Universidade do Sul de Santa Catarina
ICSC

Completed

Pre- and Postoperative Cardiopulmonary Rehabilitation Reduces Complications After Coronary Artery Bypass Surgery: A Randomized Trial

Coronary Artery Bypass Surgery
Immutep S.A.S.
SGS Aster-Cephac (CRO)

Completed

A Randomized Phase I Study of a Hepatitis B Antigen Combined With IMP321

Healthy

France
Royal Berkshire NHS Foundation Trust

Completed

Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study

Pain, Postoperative

United Kingdom
Pfizer

Completed

A Randomized, Double-Blind Study of the Efficacy and Safety of Valdecoxib Compared to Placebo for Treatment of Post- Cholecystectomy Surgery Pain

Pain | Laparoscopic Cholecystectomy

United States
Aktion Bronchialkarzinom e.V.

Completed

Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy.

Non-Small-Cell Lung Carcinoma

Germany
POZEN

Completed

An Open-Label, Randomized, Comparative 3-Way Cross-Over Study to Evaluate the Effect of Food on the 24-Hour Intragastric pH at Day 5 After Twice Daily Oral Administration of PN 200 (Omeprazole/Naproxen) in Healthy Volunteers

Healthy

United States
Nanjing Medical University
HRSA/Maternal and Child Health Bureau

Completed

Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy (DTMPCA)

Postoperative Pain | Post Operative Analgesia | Patient-Controlled Analgesia | Abdominal Surgeries

China
Soroka University Medical Center

Completed

Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants

Iron Deficiency Anemia | Infectious Diseases | Undernutrition

Israel
Pfizer

Completed

Randomized, Double Blind, Multicenter Study of the Safety and Efficacy of Valdecoxib 40 mg Once Daily Compared With Diclofenac 75 mg Twice Daily in Acute Low Back Pain

Low Back Pain

Chile, Venezuela, Ecuador, Colombia, Brazil, Mexico, Argentina, Peru, Costa Rica
University of Oulu
Finnish Cultural Foundation; Juho Vainio Foundation; Ministry of Education; Oulu... and other collaborators

Completed

Exercise and Prevention of Hip Fractures

Osteoporosis | Bone Mineral Density | Fractures | Balance | Strength

Finland
Pfizer

Completed

Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee

Osteoarthritis | Knee

Korea, Republic of
Critical Therapeutics

Terminated

Zileuton CR vs Placebo in Poorly Controlled Asthma Patients on Moderate Dose ICS

Asthma

United States
Pfizer

Completed

An Open, Prospective, Randomized, Multicenter Study of the Efficacy and Safety of Intravenous Followed by Oral Azithromycin Versus Cefuroxime Alone or With Oral Erythromycin for the Treatment of Chinese Patients Who Were Hospitalized for Pneumonia

Pneumonia

China
University of Campania "Luigi Vanvitelli"

Completed

Bedtime Insulins and Oral Antihyperglycemic Drugs in Type 2 Diabetes

Hypoglycemia | Type 2 Diabetes Mellitus

Italy
Sanofi

Completed

Continuous Glucose Monitoring System (CGMS) in Type 2 Diabetic Patients Inadequately Controlled by Metformine Monotherapy; Analyze of Glycemic Profile Before and After Association of Glimepiride

Diabetes Mellitus

France
Icagen
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Terminated

A Stratified Sickle Event Randomized Trial (ASSERT) (ASSERT)

Sickle Cell Disease

United States, France, United Kingdom, Brazil, Jamaica, Trinidad and Tobago
Pfizer

Completed

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Clarithromycin Extended Release for the Treatment of Pneumonia in Adult Patients

Pneumonia

United States, Canada, Russian Federation, India, Argentina, Estonia, Lithuania
Dafra Pharma

Completed

Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria

Plasmodium Falciparum Malaria

Cameroon, Mali, Rwanda, Sudan
Shen-Zhen City Maternity and Child Healthcare Hospital

Completed

Ovarian Laser Treatment in Women With Polycystic Ovarian Syndrome: A Randomized Study on the Laser Dose

Polycystic Ovary Syndrome | Infertility | Anovulation
Pfizer

Completed

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Mild to Moderate Pneumonia in Adult Patients

Pneumonia

Canada, United States, Russian Federation, India, Lithuania, Chile, Mexico, Peru
Pfizer

Completed

Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat

Tonsillitis

France
Erasmus Medical Center

Completed

Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patients (mec-2005-290)

Quality of Life | Acromegaly
Deutsches Herzzentrum Muenchen
Boston Scientific Corporation

Unknown

Randomized Study of Radiofrequency- vs. Cryo-Ablation for Typical Isthmus-Dependent Atrial Flutter

Atrial Flutter

Germany
AstraZeneca

Terminated

GALLEX 4 - Long-Term Extension Study to Evaluate Tesaglitazar Therapy in Patients With Type 2 Diabetes

Type 2 Diabetes

Italy, Poland, South Africa, Malaysia, Hungary, Belgium, Slovakia, Philippines, Thailand, Hong Kong
University Hospital, Grenoble
Etablissement Français du Sang

Terminated

REPI : a Randomized Open Label Trial Evaluating the Use of APC in Pre-Implantation Reconstruction of Maxilla

Tooth Loss | Jaw, Edentulous | Maxillary Diseases

France
Santéclair

Completed

The VEPRO Trial: A Cross-Over Randomised Controlled Trial Comparing 2 Corrective Lenses for Patients With Presbyopia (VEPRO)

Presbyopia

France
Patton Medical Devices
Medstar Health Research Institute; Valeritas, Inc.

Completed

A Prospective, Randomized, Parallel Crossover Study Demonstrating Subject Wearability and Usability of the I-Port Injection Port

Type 1 Diabetes | Type 2 Diabetes

United States
National Center for Complementary and Integrative...

Completed

Acupuncture and Moxa: A Randomized Clinical Trial for Chronic Diarrhea in HIV Patients

HIV Infections

United States
Federal University of São Paulo

Terminated

Sub-Tenon's Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System for Cataract Surgery

Inflammation | Bacterial Infections

Brazil
NeurogesX

Completed

Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia

Pain | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster

United States
Kaohsiung Medical University Chung-Ho Memorial...

Completed

A Randomized Trial of 24-Week Versus 48-Week Courses of Peginterferon Plus Ribavirin for HCV Genotype-1 Patients

Chronic Hepatitis C | Genotype

Taiwan
Ash Access Technology

Unknown

A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis

End Stage Renal Disease

United States
National Institute of Mental Health (NIMH)

Completed

Clinical Trial of Pramipexole in Bipolar Depression

Bipolar Disorder

United States
National Cancer Institute (NCI)

Completed

A Randomized Study of the Effect of Adjuvant Chemotherapy With Doxorubicin and Ifosfamide With Mesna in the Treatment of High-Grade Adult Extremity Soft Tissue Sarcoma

Sarcoma

United States
National Cancer Institute (NCI)

Completed

A Randomized Pilot Study for the Treatment of AIDS or AIDS Related Complex With an Alternating or Simultaneous Combination Regimen of AZT and 2',3'-Dideoxyinosine

Acquired Immunodeficiency Syndrome | AIDS-Related Complex

United States
National Institute of Mental Health (NIMH)

Completed

Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial

Bipolar Disorder | Mood Disorder | Involutional Depression

United States
National Cancer Institute (NCI)

Completed

Phase I Study to Evaluate the Safety and Immunogenicity of HIV-1 Immunogen in Children With HIV-1 Infection

HIV Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Randomized Trial of Recombinant Humanized Anti-IL-2 Receptor Antibody (Daclizumab) Versus Antithymocyte Globulin (ATG) to Treat the Cytopenia of Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes

United States
National Cancer Institute (NCI)

Completed

A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma

Melanoma

United States
National Cancer Institute (NCI)

Completed

A Randomized Phase II Study of Oral Thalidomide in Patients With Hormone-Refractory Prostate Cancer

Prostatic Neoplasm

United States
National Institutes of Health Clinical Center (CC)

Completed

A Randomized Evaluation of the Effect of Routine Normal Saline Flush Versus Heparinized Saline Solution in Groshong and Groshong PICC Catheters

Thrombosis | Catheters, Indwelling

United States
National Institute of Neurological Disorders and...

Completed

Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors

Neoplasms | Kidney Neoplasms | Kidney Diseases | Retinal Diseases | Deafness

United States
National Institute of Neurological Disorders and...

Completed

Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy

Seizures | Partial Epilepsy

United States
National Institute of Arthritis and Musculoskeletal...

Completed

A Controlled Trial of Intermittent Fludarabine for Psoriatic Arthritis

Psoriasis | Arthritis, Psoriatic

United States
National Cancer Institute (NCI)

Completed

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

Sepsis | Hematologic Diseases | Breast Neoplasms | Neutropenia | Fever

United States
National Cancer Institute (NCI)

Completed

Effect of Preoperative Chemotherapy on Axillary Lymph Node Metastases in Stage II Breast Cancer: A Prospective Randomized Trial

Neoplasm Metastasis | Breast Neoplasm

United States

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