Clinical Trials Sponsored by AOTI Ltd

Total 17156 results

Hrain Biotechnology Co., Ltd.
First Affiliated Hospital of Wenzhou Medical University; Shanghai Changzheng... and other collaborators

Recruiting

Human BCMA Targeted T Cells Injection Therapy for BCMA-positive Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

China
Actelion
Chiltern International Ltd.; Medidata Solutions; Frontier Science & Technology... and other collaborators

Terminated

A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease (SERENADE OL)

Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

United States, United Kingdom, Israel, Austria, Russian Federation, Germany, Poland, Denmark, Argentina, Brazil, Bulgaria, France, Hungary, Romania, Sweden
UKK Institute
University of Oxford; University of Graz; Tampere University of Technology; Department... and other collaborators

Completed

Socio-ecological Intervention to Promote Active Commuting to Work (KÄPY)

Active Travel

Finland
Peking University First Hospital
Ministry of Science and Technology of the People´s Republic of China; Southern... and other collaborators

Unknown

Levamlodipine Maleate or Amlodipine Besylate for Treatment of Hypertension: A Comparative Effectiveness Research (LEADER)

Primary Hypertension

China
Hospital de Clinicas de Porto Alegre
Guedes da Luz Médicos Associados Sociedade Simples LTDA

Completed

Evaluation of Different Culture Media for in Vitro Fertilization

Infertility, Female

Brazil
Dr. Sabrina Overhagen
Scitech Produtos Medicos Ltda; FCRE (Foundation for Cardiovascular Research...

Active, not recruiting

SOLARIS Peripheral PMCF Trial

Peripheral Arterial Disease | Iliac Artery Stenosis | Common Femoral Artery Stenosis

Netherlands, Germany, Italy
Spanish Cooperative Group for the Treatment of...
Sanofi; Roche Pharma AG

Completed

Study of Bevacizumab Alone or Combined With Capecitabine and Oxaliplatin as Support Therapy in Metastatic Colorectal Cancer Patients

Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Combination Therapy With Cetuximab and FOLFOX4 in Patients With Colorectal Cancer

Colorectal Cancer

Spain
University of Sao Paulo
Hospital Alemão Oswaldo Cruz; Traumec Tecnologia e Implantes Ortopedicos Ltda

Recruiting

Evaluation of Chest Wall Motility After MIRPE

Funnel Chest

Brazil
Centre Oscar Lambret
Bristol-Myers Squibb; Anticancer Fund, Belgium; CTD-CNO; ECS-Progastrin SA

Active, not recruiting

Nivolumab in Combination With Metronomic Chemotherapy in Paediatrics Refractory / Relapsing Solid Tumors

Childhood Solid Tumor

France, Belgium
Spanish Cooperative Group for the Treatment of...
Merck Sharp & Dohme LLC

Terminated

Phase II Study to Evaluate Safety and Efficacy of Cetuximab in Combination With XELOX for 12 Weeks Followed by Maintenance Treatment With Cetuximab Plus Capecitabine as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer.

Metastatic Colorectal Cancer

Spain
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
The First Affiliated Hospital of Nanchang University; Chinese PLA General Hospital and other collaborators

Not yet recruiting

Evaluate the Safety and Effectiveness of the Endoscopic Surgical Instrument Control System (SP1000).

Urologic Neoplasms

China
Beijing Konruns Pharmaceutical Co., Ltd.
West China Hospital; Beijing Tongren Hospital; National Cancer Center/Cancer...

Recruiting

A Phase 1 Study of CX1003 (Kanitinib) in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Beijing 302 Hospital
Maternal and Child Health Hospital of Hubei Province; Huoshenshan Hospital; VCANBIO... and other collaborators

Completed

Treatment With Human Umbilical Cord-derived Mesenchymal Stem Cells for Severe Corona Virus Disease 2019 (COVID-19)

Corona Virus Disease 2019(COVID-19)

China
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer... and other collaborators

Completed

Experimental Falciparum Transmission to Anopheles (EFITA)

Malaria

Australia
HeNan Sincere Biotech Co., Ltd
Beijing YouAn Hospital; Beijing Ditan Hospital; Peking Union Medical College... and other collaborators

Completed

A Drug Safety and Dose-exploratory Clinical Study of Azvudine Tablets in Patients Who Have Not Received Anti-HIV Treatment (FNC)

AIDS

China
Abbott Medical Devices
KU Leuven; Thoratec Corporation; Cliniques universitaires Saint-Luc- Université... and other collaborators

Completed

BeneMACS Study:HeartMate 2 (HM2)Left Ventricular Assist Device (LVAD) Survival in Non Transplant Patients is Equal/Better Than Results in Medical Literature (BeneMACs)

Heart Failure

Belgium
Tang-Du Hospital
Changhai Hospital; The First Affiliated Hospital of Guangzhou Medical University and other collaborators

Unknown

Study of Interventional Pulmonologic Treatment of Malignant Central Airway Stricture

Airway Obstruction

China
Boryung Pharmaceutical Co., Ltd
Asan Medical Center; Chonnam National University Hospital; Seoul National University... and other collaborators

Completed

A Valsartan 80 Mg-Referenced, Therapeutic Exploratory Clinical Study to Evaluate the Antihypertensive Efficacy of Fimasartan 30 mg During 24 Hours in Patients With Mild to Moderate Essential Hypertension

Essential Hypertension

Korea, Republic of
University Hospital Southampton NHS Foundation...
Cardiff University; University of Oxford; University of Southampton; Cardiff and... and other collaborators

Recruiting

Cortical Disarray Measurement in Mild Cognitive Impairment and Alzheimer's Disease (CONGA)

Dementia | Alzheimer Disease | Mild Cognitive Impairment

United Kingdom
Qilu Pharmaceutical Co., Ltd.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Chinese... and other collaborators

Not yet recruiting

Gefitinib Combine Radiotherapy as Therapy for Patients With NSCLC Harbouring Sensitive Mutations of EGFR

Lung Cancer

China
Epicentre
Children's Hospital Medical Center, Cincinnati; Medecins Sans Frontieres, Netherlands and other collaborators

Completed

Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Niger (ROSE)

Severe Rotavirus Gastroenteritis

Niger
PT Bio Farma
Sinovac Life Sciences Co., Ltd.; Faculty of Medicine Universitas Padjadjaran; National Intitute of Health Research and Development, Ministry of Health Republic of Indonesia

Completed

Efficacy, Safety and Immunogenicity Study of SARS-CoV-2 Inactivated Vaccine (COVID-19)

SARS-CoV2 Infection

Indonesia
Nazarbayev University Medical Center
Eurasia Invest Ltd.; Ministry of Education and Science, Republic of Kazakhstan and other collaborators

Completed

Effect of Sublimated Mare Milk Supplement on Gut Microbiome in Psoriasis Patients

Psoriasis

Kazakhstan
Anaiah Healthcare Pvt Ltd
The Leeds Teaching Hospitals NHS Trust; Brighton and Sussex University Hospitals... and other collaborators

Unknown

ESj- Powder Complete T&A Study (ESj)

Child Nutrition Disorders | Child Malnutrition

United Kingdom
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer... and other collaborators

Completed

Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent (OZGAM)

Malaria

Australia
Johns Hopkins Bloomberg School of Public Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Enhancing Ugandan HIV-Affected Child Development With Caregiver Training (MISC)

HIV

Uganda
Tang-Du Hospital
Changhai Hospital; The First Affiliated Hospital of Guangzhou Medical University and other collaborators

Unknown

Diagnosis of Individuals With Pulmonary Nodules by Different Bronchoscopy Combination

Lung Neoplasms | Bronchoscopy | Early Diagnosis

China
Tang-Du Hospital
Changhai Hospital; The First Affiliated Hospital of Guangzhou Medical University and other collaborators

Terminated

Role of Bronchoscopy in Early Lung Cancer Screening of High Risk Population

Lung Neoplasms

China
Tang-Du Hospital
Changhai Hospital; The First Affiliated Hospital of Guangzhou Medical University and other collaborators

Unknown

Study of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic Stricture

Obstructive Airway Disease

China
Glycemic Index Laboratories, Inc
University of Toronto; University of Guelph; University of Sydney; Agriculture... and other collaborators

Completed

Effect of the Molecular Weight of Oat β-glucan on Its Ability to Lower Serum Cholesterol (Bluebird)

Hypercholesterolemia

Canada, Australia, United Kingdom
Academisch Medisch Centrum - Universiteit van Amsterdam...
Patient-Led Research Collaborative Long COVID

Recruiting

Skeletal Muscle in PASC and ME/CFS Patients (MUSCLE-PASC)

ME/CFS | LONG-COVID | Post-acute Sequelae of COVID-19

Netherlands
Hospital de Clinicas de Porto Alegre
Guedes da Luz Médicos Associados Sociedade Simples LTDA

Completed

Heated and Non Heated Ovarian Aspiration Needle Protocol

Infertility, Female

Brazil
Vanderbilt University Medical Center
National Center for AIDS/STD Control and Prevention, China CDC

Completed

Multi-component HIV Intervention Packages for Chinese Men Who Have Sex With Men -Test, Link and Care (TLC) (MP3)

HIV/AIDS
Spanish Cooperative Group for the Treatment of...
Sanofi; Hoffmann-La Roche

Completed

Efficacy and Safety Study of Combination Therapy With Docetaxel-oxaliplatin-capecitabine in Patients With Advanced Gastric Adenocarcinoma and Intermediate General Status

Gastric Cancer

Spain
Xuanwu Hospital, Beijing
H. Lundbeck A/S; Hoffmann-La Roche; Genentech, Inc.; Life Molecular Imaging SA; APRINOIA... and other collaborators

Recruiting

A Direct Comparative Study of Tau Tracer in Patients With Alzheimer's Disease (HTH)

Alzheimer Disease

China
The Behavioural Insights Team
Brac; BRAC Institute of Governance and Development; Unilever U.K. Central Resources... and other collaborators

Completed

The Effect of Behaviour Change Interventions on Use of Public Handwashing Stations in Bangladesh

Covid19 | Hand Washing | Handwashing

Bangladesh
Concordia Dent Srl
Carol Davila University of Medicine and Pharmacy; Romanian National Authority... and other collaborators

Completed

New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin (HAMELDENT)

Chronic Periodontitis

Romania
Starpharma Pty Ltd
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Safety and Acceptability of SPL7013 Gel (VivaGel™) in Sexually Active Women

Healthy

United States, Puerto Rico
Insight Medtech Co., Ltd.
Shanghai Zhongshan Hospital; Guangdong Provincial People's Hospital; Beijing... and other collaborators

Recruiting

Comparison of PFA vs. RFA in Patients With Symptomatic Paroxysmal Atrial Fibrillation.

Arrhythmias, Cardiac | Paroxysmal Atrial Fibrillation

China
ThermoMind Ltd.
M.D. Anderson Cancer Center; Technion, Israel Institute of Technology; Sheba... and other collaborators

Recruiting

ThermoBreast - Non-contact Breast Cancer Imaging Using AI-enhanced Thermography. (ThermoBreast)

Breast Cancer

Germany
SpeeDx Pty Ltd
German Federal Ministry of Education and Research; Wellcome Trust; Biomedical... and other collaborators

Not yet recruiting

Susceptibility Testing In Neisseria Gonorrhoeae (STING) Study, Assessing the Performance of a New Rapid Test for Gonorrhoea Antibiotic Resistance, in a Cohort of 100 Culture Positive Neisseria Gonorrhoeae Infections (STING)

Gonorrhea | Diagnosis | Resistance Bacterial
Beth Israel Deaconess Medical Center
Rabin Medical Center; Assuta Medical Center; Eyefree Assisting Communication Ltd and other collaborators

Recruiting

Eyecontrol coMmunication Platform for dEliRium manaGemEnt in Intensive Care Units (EMERGE) (EMERGE)

Delirium | Critical Illness | Delirium in Old Age | Intensive Care Unit Delirium

United States, Israel
International Centre for Diarrhoeal Disease Research...
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh; University... and other collaborators

Completed

Low-Cost and Reusable Thermal Jacket for Managing Preterm or Low Birth Weight Neonates.

Preterm | Low Birthweight | Hypothermia Neonatal

Bangladesh
Vitaflo International, Ltd
University College London Hospitals; University Medical Center Groningen; University... and other collaborators

Completed

Glycosade v UCCS in the Dietary Management of Hepatic GSD (Glyde)

Glycogen Storage Disease

United States, United Kingdom, France, Netherlands
Philips (China) Investment CO., LTD
Peking University First Hospital; Ruijin Hospital; Beijing Tongren Hospital; Fu... and other collaborators

Unknown

The Efficacy of PAP Therapy on Reducing AF Recurrence in Patients With Morbidity of OSA (AFOSA)

Atrial Fibrillation | Obstructive Sleep Apnea

China
GeneScience Pharmaceuticals Co., Ltd.
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Children's... and other collaborators

Completed

Phase III Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children

Growth Hormone Deficiency

China
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Active, not recruiting

Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men

Chlamydia | Gonorrhea | Syphilis

United States
KU Leuven
Boehringer Ingelheim; Life Sciences Research Partners; Fund for Clinical Cardiovascular...

Active, not recruiting

STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction (STREAM-2)

Myocardial Infarction

Canada, France, Mexico, Australia, Brazil, Chile, Montenegro, Russian Federation, Serbia, Spain
União Química Farmacêutica Nacional S/A
Buranello e Rodrigues Consultoria em Desenvolvimento Farmacêutico Ltda ME

Suspended

Study With Heparin Sodium in Intravenous Administration

Heparin

Brazil

Clinical Trials Sponsored by AOTI Ltd

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Medical Conditions

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CROs by country

CROs in Peru

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