Clinical Trials Sponsored by McGuire Research Institute

Total 17013 results

University of Virginia
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Diagnostics and Pharmacotherapy for Severe Forms of TB (DMID 15-0100)

Tuberculosis
Institute of Agrochemistry and Food Technology,...
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la... and other collaborators

Completed

The Impact of Maternal Microbes on Infant Health Programming (MAMI)

Healthy

Spain
UMC Utrecht
German Cancer Research Center (DKFZ), Heidelberg, Germany; German Sport University... and other collaborators

Not yet recruiting

Personalized Live-remote Exercise Training for Cancer Survivors (LION)

Neoplasms

Netherlands
Erasmus Medical Center
Radboud University Medical Center; National Institute for Public Health and... and other collaborators

Not yet recruiting

Quinolone Resistance Profiles and Mechanisms of Staphylococcus Aureus and Escherichia Coli From Humans, Chicken and Catfish Farms in Indonesia (QUINDO)

Drug Resistance, Microbial
Instituto Nacional de Investigacao em Saude, Angola
FUNDAÇAO CALOUSTE GULBENKIAN; FUNDACIÓN BANCARIA CAIXA D'ESTALVIS I PENSIONS... and other collaborators

Recruiting

LEARNER- Low dosE AspiRiN prEterm tRial (Angola) (LEARNER)

Pregnancy Complications | Pregnancy Related | Sickle Cell Disease | Pre-Eclampsia

Angola
Columbia University
Universitat Autonoma de Barcelona; Instituto de Salud Carlos III; University... and other collaborators

Active, not recruiting

Treatment of TK2 Deficiency With Thymidine and Deoxycytidine

Thymidine Kinase 2 Deficiency | Mitochondrial DNA Depletion Syndrome 2 Myopathic Type

United States
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
National Health Research Institutes, Taiwan
National Taiwan University Hospital; China Medical University Hospital; Chang... and other collaborators

Unknown

SLOG vs mFOLFIRINOX as the First-line Treatment in Locally Advanced Uncresectable or Metastatic Pancreatic Cancer (Pancreas)

Locally Advanced or Metastatic Pancreatic Cancer

Taiwan
PHAC/CIHR Influenza Research Network
University of British Columbia; GlaxoSmithKline; CHU de Quebec-Universite Laval; Centre de recherche du Centre hospitalier universitaire de Sherbrooke and other collaborators

Completed

Surveillance for Adverse Events Following Influenza Immunization

Influenza | Vaccines Adverse Reaction

Canada
New York City Department of Health and Mental Hygiene
Public Health Solutions; The New York Academy of Medicine; New York City Health... and other collaborators

Active, not recruiting

ActionHealthNYC Research Study

Health Services Accessibility

United States
University of British Columbia
University of Manitoba; The Hospital for Sick Children; McGill University Health... and other collaborators

Active, not recruiting

The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis (OPT-JIA)

Juvenile Idiopathic Arthritis

Canada
Shepherd Center, Atlanta GA
Patient-Centered Outcomes Research Institute; University of Colorado, Denver; Massachusetts General Hospital and other collaborators

Completed

Comparative Effectiveness Study Telerehab Versus Conventional

Multiple Sclerosis

United States
Radboud University Medical Center
Amsterdam UMC, location VUmc; ZonMw: The Netherlands Organisation for Health... and other collaborators

Recruiting

Effectiveness of Focal Therapy in Men With Prostate Cancer (ENFORCE)

Prostate Cancer | Prostate Neoplasm

Netherlands
Tan Tock Seng Hospital
Melbourne Health; National University Hospital, Singapore; Samsung Medical Center and other collaborators

Recruiting

Early Oral Step-down Antibiotic Therapy for Uncomplicated Gram-negative Bacteraemia

Gram-negative Bacteraemia

Singapore
University Institute of Maia
University of Connecticut; Aveiro University; Hospital Infante D. Pedro, Centro... and other collaborators

Completed

The Hypotensive Effects of Home-Based Isometric Handgrip Training in Older Adults With Pre-Hypertension and Hypertension - The HoldAge Trial

Hypertension | Pre-Hypertension

United States, Portugal
University of Manchester
University of Nottingham; Queen Mary University of London; Manchester University... and other collaborators

Completed

What Are the Benefits and Harms of Risk Stratified Screening in the NHS Breast Screening Programme: Study Protocol

Breast Cancer

United Kingdom
Mazonson & Santas Inc.
University of California, San Diego; University of Wisconsin, Madison; Stanford... and other collaborators

Unknown

Aging With Dignity, Health, Optimism and Community (ADHOC)

HIV

United States
Sunnaas Rehabilitation Hospital
Sahlgrenska University Hospital, Sweden; Sheba Medical Center; China Rehabilitation... and other collaborators

Completed

Sunnaas International Network´s Stroke Study (SINs)

Cerebral Stroke

United States, China, Israel, Norway, Palestinian Territory, occupied, Russian Federation, Sweden
Peking Union Medical College Hospital
Central South University; Zhejiang University; Beijing Children's Hospital; Shenzhen... and other collaborators

Recruiting

Observational Study of Pediatric Rheumatic and Immunologic Diseases in China: The CAPRID Registry

Autoimmune Diseases | Autoinflammatory Diseases

China
Marie Hudson, MD
Assistance Publique - Hôpitaux de Paris; Medical University of South Carolina; Centre hospitalier de l'Université de Montréal (CHUM) and other collaborators

Recruiting

Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis (CARE-SSc)

Mesenchymal Stem Cells | Sclerosis, Systemic

Canada
NICHD Global Network for Women's and Children's...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Global Network Implementation of Helping Babies Breathe (HBB)

Perinatal Mortality

Kenya, India
University of Iowa
Patient-Centered Outcomes Research Institute; Medical University of South Carolina and other collaborators

Enrolling by invitation

Neuroendocrine Tumors - Patient Reported Outcomes (NET-PRO)

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Lung Neuroendocrine Neoplasm | Gastroenteropancreatic Neuroendocrine Tumor

United States
Hospital Universitario 12 de Octubre
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Active, not recruiting

Empirical Treatment Against Cytomegalovirus and Tuberculosis in HIV-infected Infants With Severe Pneumonia (EMPIRICAL)

Pneumonia | HIV/AIDS | Tuberculosis | Cytomegalovirus Infections

Zimbabwe, France, Côte D'Ivoire, Italy, Malawi, Mozambique, Netherlands, Spain, Uganda, United Kingdom, Zambia
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Recruiting

Cabozantinib and Lanreotide as Treatment for Gastroenteropancreatic Neuroendocrine Tumors

Neuroendocrine Tumors,Gastroenteropancreatic

Taiwan
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Completed

A Randomized Study of GEMOX With or Without Cetuximab in Locally Advanced and Metastatic BTC (BTC)

Cholangiocarcinoma | Adenocarcinoma of Gallbladder

Taiwan
Michael Shy
Johns Hopkins University; University of Colorado, Denver; King's College Hospital... and other collaborators

Recruiting

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others (INC-6601)

Charcot Marie Tooth Disease

United States, Australia, Italy, United Kingdom, Canada
International Cancer Research Group, United Arab...
King Saud University Medical City, Riyadh, Saudi Arabia; Max-Planck-Institut... and other collaborators

Recruiting

Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies. (ICRG0201)

Hormonal Receptors Positive, HER2 Negative, Advanced Breast Cancer

Algeria, Jordan, Saudi Arabia
Johannes Gutenberg University Mainz
Sanofi; Bayer; Boehringer Ingelheim; German Federal Ministry of Education and Research and other collaborators

Completed

Evaluation of Oral Anticoagulation With Vitamin K Antagonists - The thrombEVAL Study Programme (thrombEVAL)

Atrial Fibrillation | Venous Thromboembolism | Anticoagulant Antagonists, Vitamin K and Other Coagulants Causing Adverse Effects in Therapeutic Use

Germany
Memorial Sloan Kettering Cancer Center
University of California, Los Angeles; Ferring Pharmaceuticals; Wayne State University and other collaborators

Completed

3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy

Prostate Cancer

United States
Children's Hospital of Philadelphia
Baylor College of Medicine; Washington University School of Medicine; National... and other collaborators

Recruiting

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome (LEOPARDS)

Acute Respiratory Distress Syndrome

United States
Hai-Qiang Mai,MD,PhD
Zhejiang Cancer Hospital; Fudan University; Cancer Institute and Hospital, Chinese... and other collaborators

Not yet recruiting

The Children and Adolescents Nasopharyngeal Carcinoma Survivor Study (CANPCSS)

NPC Patients
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
LanZhou University; Qilu Hospital of Shandong University; Tianjin Medical University... and other collaborators

Not yet recruiting

Laparoscopic Proximal Gastrectomy With Double-flap Technique Versus Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction for Proximal Early Gastric Cancer

Stomach Neoplasms

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
LanZhou University; Qilu Hospital of Shandong University; Tianjin Medical University... and other collaborators

Not yet recruiting

Feasibility and Safety of Robotic Assisted Proximal Gastrectomy With Double-flap Technique for Proximal Early Gastric Cancer

Stomach Neoplasms

China
PHAC/CIHR Influenza Research Network
GlaxoSmithKline; CHU de Quebec-Universite Laval; The Ottawa Hospital; Hamilton... and other collaborators

Completed

Surveillance for Adverse Events Following Pandemic H1N1 Immunization

Novel Influenza A/H1N1
Insel Gruppe AG, University Hospital Bern
The Hospital for Sick Children; Children's Hospital of Philadelphia; Charite... and other collaborators

Recruiting

Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2) (OPTIMISE-2)

Airway Management

Switzerland, Canada, Germany
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Multiple Myeloma Research Consortium
Bristol-Myers Squibb; Memorial Sloan Kettering Cancer Center; Washington University... and other collaborators

Active, not recruiting

Immuno-Oncology Drugs Elotuzumab, Anti-LAG-3 and Anti-TIGIT

Multiple Myeloma | Relapsed Refractory Multiple Myeloma

United States
Queen Mary University of London
National Institute for Health Research, United Kingdom; WBIC), Cambridge. University... and other collaborators

Unknown

IS Metomidate PET-CT Superior to Adrenal Venous Sampling in Predicting Outcome From Adrenalectomy in Patients With Primary Hyperaldosteronism (MATCH)

Primary Aldosteronism | Hyperaldosteronism

United Kingdom
The Hospital for Sick Children
Karolinska University Hospital; Sunnybrook Health Sciences Centre; University... and other collaborators

Recruiting

RIC-NEC Randomized Controlled Trial (RIC-NEC)

Necrotizing Enterocolitis

United States, Canada
Virginia Commonwealth University
Radboud University Medical Center; University of California, Los Angeles; University... and other collaborators

Recruiting

Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

Myotonic Dystrophy 1

United States, Netherlands, United Kingdom, New Zealand, Germany, Italy, Canada, France
Boston Medical Center
University of Pennsylvania; Yale University; University of Florida; University... and other collaborators

Recruiting

Multimodal Outcome CHAracterization in Comatose Cardiac Arrest Patients Registry and Tissue Repository (MOCHA)

Cardiac Arrest

United States
Jiang Jianxin
Second Affiliated Hospital, School of Medicine, Zhejiang University; Huazhong... and other collaborators

Recruiting

Prediction Study of Complications After Severe Trauma (PSCAT)

Sepsis | Trauma | Multiple Organ Dysfunction Syndrome

China
University of Manchester
Northern Care Alliance NHS Foundation Trust; Royal Free Hospital NHS Foundation... and other collaborators

Enrolling by invitation

Early Diagnosis of SSc in the General Rheumatology Clinic - Pilot

Systemic Sclerosis | Raynaud Phenomenon

United Kingdom
University of Wisconsin, Madison
Johns Hopkins University; University of Colorado, Denver; Northwestern University and other collaborators

Active, not recruiting

A Communication Tool to Assist Older Adults Facing Dialysis Choices

Kidney Diseases | Kidney Failure, Chronic | Communication | End-Stage Renal Disease | Palliative Care | End of Life | Dialysis | Renal Dialysis | Decision Making | Decision Aid | Decision Support Techniques | Nephrologists | Late-Stage Renal Disease | Life-Supporting Treatments

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Seoul National University Hospital
Pusan National University Hospital; Chonnam National University Hospital; Seoul... and other collaborators

Not yet recruiting

Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3) (Hi-DoRi-3)

Tuberculosis, Pulmonary

Korea, Republic of
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
Population Health Research Institute
Charles University, Czech Republic; Centre hospitalier de l'Université de Montréal... and other collaborators

Completed

Coronary Artery Bypass Surgery (CABG) Off or On Pump Revascularization Study (CORONARY)

the Efficacy and Safety of Off-pump CABG

Canada, China, Colombia, India, Chile, Argentina, Brazil, Czech Republic, France, Italy, Poland, Turkey, United Kingdom

Clinical Trials Sponsored by McGuire Research Institute

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