Search clinical trials for: Programmed Death Receptor

Total 20153 results

US Department of Veterans Affairs

Completed

Hyporeactivity and Gulf War Illness

Gulf War Syndrome | Chronic Fatigue Syndrome | Post-Traumatic Stress Disorder

United States
Teva GTC

Completed

Study of Nighttime Dosing of Sublingual Tizanidine (12 mg) in Multiple Sclerosis (MS) Patients With Significant Spasticity

Muscle Spasticity

Israel
US Department of Veterans Affairs

Completed

Guanfacine for the Treatment of Post Traumatic Stress Disorder (PTSD)

Post-Traumatic Stress Disorder

United States
US Department of Veterans Affairs

Completed

New Pharmacological Treatment for Obstructive Sleep Apnea

Obstructive Sleep Apnea

United States
Sanofi

Completed

Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH Safety)

Hyponatremia | Inappropriate ADH Syndrome

United States, France, Brazil, Russian Federation, Australia, Germany, Switzerland, Belgium, Hungary, Hong Kong, Canada
US Department of Veterans Affairs

Completed

Estrogen Alternatives Study

Healthy

United States
Herlev Hospital

Unknown

Pulse Wave Velocity, Pulse Wave Morphology and Blocking of the Reninangiotensin System in Patients With Chronic Kidney Disease

Cardiovascular Diseases | Kidney Failure, Chronic

Denmark
Allergan

Completed

Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Canada
Bp Consulting, Inc
Allergan

Completed

Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Canada
National Cancer Institute (NCI)

Completed

Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Harrison Clinical Research
Merck KGaA, Darmstadt, Germany; AstraZeneca

Completed

Pharmocokinetic/Pharmacodynamic (PK/PD) Study of the Combination Cetuximab/Gefitinib

Head and Neck Cancer | Colorectal Cancer | Non Small Cell Lung Cancer (NSCLC)

Spain, Belgium
Sanofi

Completed

Satavaptan Dose-Ranging Study in Hyponatraemic Patients With Cirrhotic Ascites (Hypo~CAT)

Liver Cirrhosis | Ascites

United States, France, Romania, Germany, Italy, Spain, Belgium, Czech Republic, Argentina, Croatia, Hungary, Canada, Australia
Sanofi

Completed

Satavaptan Dose-Ranging Study in the Prevention of Ascites (SPA)

Liver Cirrhosis | Ascites

France, Germany, Italy, Spain, Taiwan, Belgium, Czech Republic, Argentina, Croatia, Canada, Australia
Akron Children's Hospital

Completed

The Use of Nasal Phenylephrine in Infants With Bronchiolitis

Bronchiolitis
Biogen

Completed

Dose-Finding Safety Study of BIIB014 in Early-Stage Parkinson's Disease (MOBILE)

Parkinson's Disease

Poland, Israel, Serbia
University of Edinburgh
Encysive Pharmaceuticals

Unknown

Sitaxsentan in Proteinuric Chronic Kidney Disease

Proteinuria | Chronic Kidney Disease | Blood Pressure

United Kingdom
University of Vigo
Novartis; Hospital Clinico Universitario de Santiago

Completed

Comparison of the Antihypertensive Efficacy of Valsartan and Enalapril After Missing One Dose

Hypertension

Spain
Aarhus University Hospital
Hoffmann-La Roche; University of Aarhus; The Ministry of Science, Technology...

Unknown

Mutations in the Epidermal Growth Factor Receptor(EGFR) Gene in Non-Small Cell Lung Carcinoma (NSCLC) and the Relation to Response of Treatment With Erlotinib

Non-Small Cell Lung Cancer

Denmark
Assaf-Harofeh Medical Center

Unknown

CYP2D6 Genotyping by AmpliChipTM CYP450 for Tamoxifen-Treated Breast Cancer Patients

Breast Cancer

Israel
Arena Pharmaceuticals

Completed

Single-Dose Safety Study of APD791 in Healthy Volunteers

Healthy

United States
Shaddy, Robert, M.D.
GlaxoSmithKline

Completed

Study to Evaluate the Safety of Twice Daily Oral Carvedilol

Congestive Heart Failure

United States
Shaddy, Robert, M.D.
University of Utah

Completed

Safety and Efficacy Study of Carvedilol to Treat Children With Congestive Heart Failure

Congestive Heart Failure

United States
Karolinska Institutet

Completed

Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT) (SWEFOT)

Rheumatoid Arthritis
Medical University of Vienna

Completed

The Effect of an α2-Adrenoceptor Antagonist (Yohimbine) on Dynamic Autoregulation in the Human Middle Cerebral Artery and Ophthalmic Artery

Ocular Physiology | Autoregulation | Blood Flow Velocity

Austria
University of Sao Paulo

Unknown

Effect of Active Telephone Calls in the Compliance of Hypertensive Patients With Treatment

Blood Pressure

Brazil
Sanofi

Completed

Mixed Antagonist of Serotonin for Claudication Optimal Therapy (MASCOT)

Intermittent Claudication

United States, Canada, Russian Federation, Ukraine, Germany, Sweden, Belgium, Czech Republic, Mexico
Schering-Plough

Completed

Assessment of the Effectiveness of OLMETEC® and OLMETEC PLUS® for Treatment of Hypertension in Stage I and II Patients (Study P05254)(COMPLETED)

Hypertension
University of Pittsburgh
Enzon Pharmaceuticals, Inc.

Terminated

Abelcet Radiotagging Protocol: Inhaled Lipid Complex Abelcet® in Lung Transplant Recipients

Lung Diseases | Lung Transplantation

United States
Novartis Pharmaceuticals

Terminated

A Study in Patients With Diabetes Mellitus Type II of the Effect on Albuminuria of 24 Week Treatment With Valsartan, Benazepril, and Valsartan+Benazepril

Hypertension | Diabetic Nephropathy

Switzerland
University of Pittsburgh

Completed

Prospective Study of Drug Resistant Pathogens Among Liver, Intestinal and Multivisceral Transplant Recipients

Transplantation

United States
University Hospital, Limoges
Hoffmann-La Roche

Unknown

Concentration Controlled Versus Fixed Dose of MMF in Kidney Transplant Recipients

Kidney Transplant Recipients

France
Boryung Pharmaceutical Co., Ltd

Completed

Cilnidipine Effect on High Blood Pressure and Cerebral Perfusion in Ischemic Stroke Patients With Hypertension

Stroke | Hypertension

Korea, Republic of
Sanofi

Completed

Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Hyponatremia | Inappropriate ADH Syndrome

United States, Canada, Brazil, Germany, Netherlands, Portugal, Spain, Belgium, Croatia, Hungary, Hong Kong
Sanofi

Completed

A Multicenter Study to Evaluate the Efficacy and Safety of of Four Doses of SR147778 in Obese Patients

Obesity

France, Spain, Argentina, Finland, Australia
University of Sao Paulo

Completed

Effectiveness of Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis in Intraocular Pressure (IOP) After Bevacizumab

Macular Degeneration | Diabetic Retinopathy | Macular Edema

Brazil
Amgen

Completed

REKinDLE: Registry With Enbrel® or Kineret® in a Database Using Longitudinal Evaluations

Rheumatoid Arthritis
Bp Consulting, Inc

Completed

Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG)

Ocular Hypertension | Open-Angle Glaucoma

United States
National Taiwan University Hospital

Completed

The Combination Effect of Dexmedetomidine and Morphine in Postoperative Patient-Controlled Analgesia

Analgesia, Patient-Controlled | Analgesia, Postoperative
Samsung Medical Center

Completed

Increased Expression of Adiponectin Receptor 2 in the Mononuclear Cells in Children With Prader-Willi Syndrome

Obesity | Prader-Willi Syndrome
Rabin Medical Center

Unknown

Effect of Topical Brimonidine on Post Cataract Surgery Corneal Edema

Corneal Edema | Visual Acuity

Israel
AstraZeneca

Completed

Drug Interaction Study Between AZD3480 and Cytochrome P450 (Cocktail)

Alzheimer's Disease | Metabolism

Sweden
Movetis

Completed

Safety Study of Prucalopride in Healthy Volunteers

Healthy
University of Auckland, New Zealand
Auckland Medical Research Foundation; Mercia Barnes Trust of the Royal Australian...

Completed

PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene (PCOSMIC)

Polycystic Ovary Syndrome

New Zealand
Charite University, Berlin, Germany

Unknown

Effects of Endurance Training on Patients With Reduced Left Ventricular Ejection Fraction (LVEF) and Cardiac Resynchronisation Therapy Especially for Cardiac Arrhythmias

Heart Failure | Sudden Cardiac Death | Cardiac Resynchronisation Therapy

Germany
Jichi Medical University

Completed

The Japan-Combined Treatment With Olmesartan and a Calcium Channel Blocker Versus Olmesartan and Diuretics Randomized Efficacy Study (J-CORE)

Hypertension

Japan
German Breast Group
German Adjuvant Breast Cancer Group

Completed

Neoadjuvant Doxorubicin/Cyclophosphamide Followed by Docetaxel (AC-Doc) Versus Dose-Dense Doxorubicin and Docetaxel (ADoc) in Breast Cancer

Primary Breast Cancer

Germany
AstraZeneca

Completed

Determine the Effect of Multiple Doses of AZD7325, CYP Study (CYP)

Healthy Volunteer
Michael Mauer, MD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Merck... and other collaborators

Completed

Renin Angiotensin System Study (RASS/B-RASS)

Type 1 Diabetes

Canada
Bristol-Myers Squibb

Completed

Drug Interaction Study With a Potential Alzheimer's Disease Compound

Alzheimer Disease

United States
Hadassah Medical Organization

Unknown

Genetic Determinants of the Response to Salbutamol Among Asthma Patients

Asthma

Israel

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